BR112017007053A2 - compostos neuroativos e métodos de utilização deste composto. - Google Patents
compostos neuroativos e métodos de utilização deste composto.Info
- Publication number
- BR112017007053A2 BR112017007053A2 BR112017007053A BR112017007053A BR112017007053A2 BR 112017007053 A2 BR112017007053 A2 BR 112017007053A2 BR 112017007053 A BR112017007053 A BR 112017007053A BR 112017007053 A BR112017007053 A BR 112017007053A BR 112017007053 A2 BR112017007053 A2 BR 112017007053A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- methods
- neuroactive compounds
- neuroactive
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462060932P | 2014-10-07 | 2014-10-07 | |
| PCT/US2015/054551 WO2016057713A1 (en) | 2014-10-07 | 2015-10-07 | Neuroactive compounds and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017007053A2 true BR112017007053A2 (pt) | 2018-06-19 |
Family
ID=55653736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017007053A BR112017007053A2 (pt) | 2014-10-07 | 2015-10-07 | compostos neuroativos e métodos de utilização deste composto. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20170304321A1 (pt) |
| EP (1) | EP3204011A4 (pt) |
| JP (3) | JP2017530982A (pt) |
| KR (1) | KR20170065637A (pt) |
| CN (2) | CN112121171A (pt) |
| AU (2) | AU2015330906A1 (pt) |
| BR (1) | BR112017007053A2 (pt) |
| CA (1) | CA2963938C (pt) |
| IL (2) | IL292465A (pt) |
| MX (2) | MX2017004684A (pt) |
| MY (1) | MY202135A (pt) |
| PE (1) | PE20170907A1 (pt) |
| PH (1) | PH12017500639A1 (pt) |
| RU (1) | RU2764702C2 (pt) |
| SG (2) | SG11201702799UA (pt) |
| WO (1) | WO2016057713A1 (pt) |
| ZA (1) | ZA201702545B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2753632T1 (sl) | 2011-09-08 | 2023-08-31 | Sage Therapeutics, Inc. | Nevroaktivni steroidi, njihovi sestavki in uporaba |
| CN112375115A (zh) | 2013-03-13 | 2021-02-19 | 萨奇治疗股份有限公司 | 神经活性甾类化合物及其使用方法 |
| PE20161035A1 (es) | 2013-03-15 | 2016-11-13 | Global Blood Therapeutics Inc | Compuestos y usos de estos para la modulacion de la hemoglobina |
| EA202092627A1 (ru) | 2013-11-18 | 2021-09-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| TWI734665B (zh) | 2013-12-24 | 2021-08-01 | 維吉尼亞聯邦大學 | 氧化膽固醇硫酸鹽（ｏｃｓ）之用途 |
| WO2015195967A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| CN108135912B (zh) | 2015-07-06 | 2021-07-02 | 萨奇治疗股份有限公司 | 孕甾醇及其使用方法 |
| WO2017007832A1 (en) * | 2015-07-06 | 2017-01-12 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| PL3319612T3 (pl) | 2015-07-06 | 2021-12-20 | Sage Therapeutics, Inc. | Oksysterole i sposoby ich stosowania |
| PL3436022T3 (pl) | 2016-04-01 | 2022-08-08 | Sage Therapeutics, Inc. | Oksysterole i sposoby ich stosowania |
| WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| LT3481846T (lt) | 2016-07-07 | 2021-08-25 | Sage Therapeutics, Inc. | 11-pakeistieji 24-hidroksisteroliai, skirti naudoti gydant su nmda susijusias būkles |
| TW202426000A (zh) * | 2016-08-02 | 2024-07-01 | 美商杜瑞克公司 | 包含５－膽甾烯－３，２５－二醇３－硫酸酯（２５ｈｃ３ｓ）或其醫藥上可接受之鹽及至少一種環狀寡醣的組成物，以及使用彼等之方法 |
| BR112019006365A2 (pt) | 2016-09-30 | 2019-08-06 | Sage Therapeutics Inc | oxisteróis substituídos c7 e métodos de utilização dos mesmos |
| MX2019004679A (es) | 2016-10-18 | 2019-10-15 | Sage Therapeutics Inc | Oxisteroles y metodos de uso de los mismos. |
| US11149054B2 (en) * | 2016-10-18 | 2021-10-19 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| EP3335730A1 (en) * | 2016-12-15 | 2018-06-20 | Fundació Institut de Recerca Biomédica de Bellvitge (IDIBELL) | Compounds for treating x-linked adrenoleukodystrophy |
| US10857163B1 (en) | 2019-09-30 | 2020-12-08 | Athenen Therapeutics, Inc. | Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| US8604011B2 (en) * | 2004-09-27 | 2013-12-10 | The Regents Of The University Of California | Therapy for treatment of chronic degenerative brain diseases and nervous system injury |
| GB0712494D0 (en) * | 2007-06-27 | 2007-08-08 | Isis Innovation | Substrate reduction therapy |
| MX2010004682A (es) * | 2007-11-06 | 2010-05-19 | Organon Nv | Metodo de supresion de hormonas en humanos. |
| CA2722776A1 (en) * | 2008-05-09 | 2009-11-12 | Emory University | Nmda receptor antagonists for the treatment of neuropsychiatric disorders |
| WO2010065709A2 (en) * | 2008-12-03 | 2010-06-10 | Amin Khan | Hydroxamic acid derivatives, preparation and therapeutic uses thereof |
| US20110319416A1 (en) * | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
| WO2011028794A2 (en) * | 2009-09-01 | 2011-03-10 | Lazarus Therapeutics, Inc. | Treatment of huntington's disease with cycloserine and an nmda receptor antagonist |
| KR101692275B1 (ko) * | 2010-02-11 | 2017-01-04 | 노오쓰웨스턴 유니버시티 | ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도 |
| US20120035156A1 (en) * | 2010-08-09 | 2012-02-09 | Daniela Alberati | Combination of glyt1 compound with antipsychotics |
| SI2753632T1 (sl) * | 2011-09-08 | 2023-08-31 | Sage Therapeutics, Inc. | Nevroaktivni steroidi, njihovi sestavki in uporaba |
| US20150119327A1 (en) * | 2012-04-25 | 2015-04-30 | The Regents Of The University Of California | Drug screening platform for rett syndrome |
| WO2014025942A1 (en) * | 2012-08-09 | 2014-02-13 | Emory University | Nmda receptor modulators and uses related thereto |
| EA031905B1 (ru) * | 2013-01-29 | 2019-03-29 | Аптиникс Инк. | Спиролактамные модуляторы рецептора nmda и их применение |
| CA2905346A1 (en) * | 2013-03-13 | 2014-10-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| CN112375115A (zh) | 2013-03-13 | 2021-02-19 | 萨奇治疗股份有限公司 | 神经活性甾类化合物及其使用方法 |
| WO2015195967A1 (en) * | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| WO2016007762A1 (en) * | 2014-07-09 | 2016-01-14 | Duke University | Compositions and methods for the repair of myelin |
| WO2017007832A1 (en) * | 2015-07-06 | 2017-01-12 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
-
2015
- 2015-10-07 MY MYPI2017000507A patent/MY202135A/en unknown
- 2015-10-07 JP JP2017518329A patent/JP2017530982A/ja not_active Withdrawn
- 2015-10-07 AU AU2015330906A patent/AU2015330906A1/en not_active Abandoned
- 2015-10-07 PE PE2017000579A patent/PE20170907A1/es unknown
- 2015-10-07 MX MX2017004684A patent/MX2017004684A/es unknown
- 2015-10-07 SG SG11201702799UA patent/SG11201702799UA/en unknown
- 2015-10-07 IL IL292465A patent/IL292465A/en unknown
- 2015-10-07 WO PCT/US2015/054551 patent/WO2016057713A1/en active Application Filing
- 2015-10-07 EP EP15849514.3A patent/EP3204011A4/en active Pending
- 2015-10-07 RU RU2017115849A patent/RU2764702C2/ru active
- 2015-10-07 BR BR112017007053A patent/BR112017007053A2/pt not_active Application Discontinuation
- 2015-10-07 CA CA2963938A patent/CA2963938C/en active Active
- 2015-10-07 CN CN202011059273.5A patent/CN112121171A/zh active Pending
- 2015-10-07 US US15/517,886 patent/US20170304321A1/en not_active Abandoned
- 2015-10-07 CN CN201580063540.7A patent/CN107405352A/zh active Pending
- 2015-10-07 KR KR1020177012221A patent/KR20170065637A/ko not_active Application Discontinuation
- 2015-10-07 SG SG10202011773UA patent/SG10202011773UA/en unknown
-
2017
- 2017-04-02 IL IL251505A patent/IL251505B/en unknown
- 2017-04-06 PH PH12017500639A patent/PH12017500639A1/en unknown
- 2017-04-07 MX MX2021011939A patent/MX2021011939A/es unknown
- 2017-04-10 ZA ZA2017/02545A patent/ZA201702545B/en unknown
-
2020
- 2020-09-07 JP JP2020149725A patent/JP2020196759A/ja not_active Withdrawn
-
2021
- 2021-02-04 AU AU2021200721A patent/AU2021200721B2/en active Active
-
2022
- 2022-01-05 JP JP2022000454A patent/JP2022033285A/ja active Pending
- 2022-09-19 US US17/947,844 patent/US20230218638A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021200721A1 (en) | 2021-03-04 |
| CN112121171A (zh) | 2020-12-25 |
| RU2764702C2 (ru) | 2022-01-19 |
| EP3204011A4 (en) | 2018-06-20 |
| MX2021011939A (es) | 2021-11-03 |
| IL292465A (en) | 2022-06-01 |
| PE20170907A1 (es) | 2017-07-12 |
| AU2015330906A1 (en) | 2017-04-27 |
| RU2017115849A (ru) | 2018-11-13 |
| JP2020196759A (ja) | 2020-12-10 |
| CN107405352A (zh) | 2017-11-28 |
| PH12017500639A1 (en) | 2017-09-25 |
| JP2017530982A (ja) | 2017-10-19 |
| SG11201702799UA (en) | 2017-05-30 |
| SG10202011773UA (en) | 2021-01-28 |
| WO2016057713A1 (en) | 2016-04-14 |
| IL251505A0 (en) | 2017-05-29 |
| KR20170065637A (ko) | 2017-06-13 |
| MY202135A (en) | 2024-04-05 |
| ZA201702545B (en) | 2019-06-26 |
| EP3204011A1 (en) | 2017-08-16 |
| US20170304321A1 (en) | 2017-10-26 |
| CA2963938C (en) | 2023-10-24 |
| JP2022033285A (ja) | 2022-02-28 |
| CA2963938A1 (en) | 2016-04-14 |
| NZ730862A (en) | 2024-01-26 |
| US20230218638A1 (en) | 2023-07-13 |
| RU2017115849A3 (pt) | 2019-05-15 |
| MX2017004684A (es) | 2017-06-30 |
| AU2021200721B2 (en) | 2023-06-01 |
| IL251505B (en) | 2022-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |