BG34614A3 - Method for preparing derivatives of penicillanic acid - Google Patents

Method for preparing derivatives of penicillanic acid

Info

Publication number: BG34614A3
Authority: BG; Bulgaria
Prior art keywords: penicillanic acid; preparing derivatives; derivatives; preparing; acid
Prior art date: 1977-06-07

Application number

BG039910A

Other languages

Bulgarian (bg)

English (en)

Inventor

Wayne Barth

Original Assignee

Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-06-07

Filing date

1978-05-30

Publication date

1983-10-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27122691&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG34614(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1978-05-30 Application filed by Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware filed Critical Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware

1983-10-15 Publication of BG34614A3 publication Critical patent/BG34614A3/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BG039910A 1977-06-07 1978-05-30 Method for preparing derivatives of penicillanic acid BG34614A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US80432077A	1977-06-07	1977-06-07
US87938178A	1978-02-21	1978-02-21

Publications (1)

Publication Number	Publication Date
BG34614A3 true BG34614A3 (en)	1983-10-15

Family

ID=27122691

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BG042176A BG34615A3 (en)	1977-06-07	1978-05-30	Method for preparing 1- oxides of penicillanic acid
BG039910A BG34614A3 (en)	1977-06-07	1978-05-30	Method for preparing derivatives of penicillanic acid

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BG042176A BG34615A3 (en)	1977-06-07	1978-05-30	Method for preparing 1- oxides of penicillanic acid

Country Status (35)

Country	Link
AR (1)	AR224111A1 (xx)
AT (2)	AT360649B (xx)
AU (1)	AU513636B2 (xx)
BE (1)	BE867859A (xx)
BG (2)	BG34615A3 (xx)
CH (1)	CH634073A5 (xx)
CS (1)	CS208472B2 (xx)
DD (2)	DD148585A5 (xx)
DE (2)	DE2824535C3 (xx)
DK (1)	DK155740C (xx)
EG (1)	EG13869A (xx)
FI (1)	FI66003C (xx)
FR (2)	FR2393804A1 (xx)
GB (1)	GB2000138B (xx)
GR (1)	GR72255B (xx)
HK (1)	HK13184A (xx)
HU (1)	HU180042B (xx)
IE (1)	IE47079B1 (xx)
IL (2)	IL54867A (xx)
IN (1)	IN149747B (xx)
IT (1)	IT1096381B (xx)
KE (1)	KE3355A (xx)
LU (1)	LU79774A1 (xx)
MY (1)	MY8500092A (xx)
NL (2)	NL180009C (xx)
NO (2)	NO151746C (xx)
NZ (1)	NZ187476A (xx)
OA (1)	OA05964A (xx)
PH (3)	PH26810A (xx)
PL (1)	PL114501B1 (xx)
PT (1)	PT68146A (xx)
SE (2)	SE436206B (xx)
SG (1)	SG65383G (xx)
SU (1)	SU860706A1 (xx)
YU (1)	YU41829B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU77306A1 (xx) *	1977-05-09	1979-01-18
DE2912511C2 (de) *	1977-06-07	1982-06-24	Pfizer Inc., 10017 New York, N.Y.	Pharmazeutische Zusammensetzung, enthaltend Penicillansäure
DK155942C (da) *	1977-12-23	1989-10-23	Pfizer	Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
JPS54126735A (en) *	1978-03-24	1979-10-02	Toyama Chem Co Ltd	Bactericidal composition for medical use
US4241050A (en) *	1978-09-01	1980-12-23	Pfizer Inc.	Penam 1,1-dioxides as beta-lactamase inhibitors
CA1158639A (en) *	1978-12-11	1983-12-13	Eric M. Gordon	6-bromopenicillanic acid sulfone
IE49880B1 (en) *	1979-02-13	1986-01-08	Leo Pharm Prod Ltd	Penicillin derivatives
SE449103B (sv) *	1979-03-05	1987-04-06	Pfizer	Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4714761A (en) *	1979-03-05	1987-12-22	Pfizer Inc.	6,6-dihalopenicillanic acid 1,1-dioxides and process
US4420426A (en)	1979-03-05	1983-12-13	Pfizer Inc.	6-Alpha-halopenicillanic acid 1,1-dioxides
GB2045236A (en) *	1979-03-26	1980-10-29	Hoechst Uk Ltd	Oxapenem derivatives
US4244951A (en)	1979-05-16	1981-01-13	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4309347A (en)	1979-05-16	1982-01-05	Pfizer Inc.	Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
IE49768B1 (en) *	1979-05-21	1985-12-11	Leo Pharm Prod Ltd	6beta-halopenicillanic acid derivatives
DE3051044C2 (xx) *	1979-06-19	1989-03-30	Leo Pharmaceutical Products Ltd. A/S (Loevens Kemiske Fabrik Produktionsaktieselskab), Ballerup, Dk
US4256733A (en) *	1979-09-26	1981-03-17	Pfizer Inc.	Acetoxymethyl penam compounds as β-lactamase inhibitors
US4432970A (en) *	1979-11-23	1984-02-21	Pfizer Inc.	6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
IL61880A (en) *	1980-01-21	1984-11-30	Bristol Myers Co	2beta-chloromethyl-2alpha-methylpenam-3alpha-carboxylic acid sulfone derivatives,their preparation and pharmaceutical compositions containing them
US4488994A (en) *	1980-09-08	1984-12-18	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4432903A (en) *	1980-09-08	1984-02-21	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4474698A (en) *	1980-12-11	1984-10-02	Pfizer Inc.	Process for preparing esters of penicillanic acid sulfone
US4419284A (en) *	1981-03-23	1983-12-06	Pfizer Inc.	Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
EP0069962B1 (en) *	1981-07-15	1985-01-02	Kanebo, Ltd.	Novel ester of 1,1-dioxopenicillanic acid, process for production thereof, and use thereof as beta-lactamase inhibitor
PT76526B (en) *	1982-04-19	1986-01-21	Gist Brocades Nv	Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides
US4502988A (en) *	1983-08-08	1985-03-05	Eli Lilly And Company	Oxidation process
EP0139047A1 (en) *	1983-10-18	1985-05-02	Gist-Brocades N.V.	Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4647457A (en) *	1983-12-16	1987-03-03	Hoffmann-La Roche Inc.	Penicillanic acid derivatives
ATE77821T1 (de) *	1986-04-10	1992-07-15	Leo Pharm Prod Ltd	Verfahren zur herstellung von penicillansaeurederivaten.
GB8808701D0 (en) *	1988-04-13	1988-05-18	Erba Carlo Spa	Beta-lactam derivatives
CN102977120B (zh) *	2012-12-14	2015-05-27	江西富祥药业股份有限公司	一种舒巴坦匹酯制备及结晶方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3197466A (en) *	1961-10-30	1965-07-27	Smith Kline French Lab	Penicillin sulfoxides and process
LU77306A1 (xx) *	1977-05-09	1979-01-18
AU3796278A (en) *	1977-07-13	1980-01-17	Glaxo Group Ltd	Penams and azetidinones

1978
- 1978-05-04 IN IN327/DEL/78A patent/IN149747B/en unknown
- 1978-05-09 PH PH21116A patent/PH26810A/en unknown
- 1978-05-16 YU YU1170/78A patent/YU41829B/xx unknown
- 1978-05-18 OA OA56500A patent/OA05964A/xx unknown
- 1978-05-20 EG EG322/78A patent/EG13869A/xx active
- 1978-05-30 BG BG042176A patent/BG34615A3/xx unknown
- 1978-05-30 BG BG039910A patent/BG34614A3/xx unknown
- 1978-06-01 CS CS783579A patent/CS208472B2/cs unknown
- 1978-06-02 AU AU36838/78A patent/AU513636B2/en not_active Ceased
- 1978-06-02 GB GB7826308A patent/GB2000138B/en not_active Expired
- 1978-06-05 DE DE2824535A patent/DE2824535C3/de not_active Expired
- 1978-06-05 DE DE2857263A patent/DE2857263C3/de not_active Expired
- 1978-06-05 GR GR56439A patent/GR72255B/el unknown
- 1978-06-06 DK DK251478A patent/DK155740C/da not_active IP Right Cessation
- 1978-06-06 BE BE188352A patent/BE867859A/xx not_active IP Right Cessation
- 1978-06-06 CH CH618078A patent/CH634073A5/fr not_active IP Right Cessation
- 1978-06-06 IT IT24270/78A patent/IT1096381B/it active Protection Beyond IP Right Term
- 1978-06-06 SU SU782624408A patent/SU860706A1/ru active
- 1978-06-06 NZ NZ187476A patent/NZ187476A/xx unknown
- 1978-06-06 FR FR787816893A patent/FR2393804A1/fr active Granted
- 1978-06-06 AT AT411278A patent/AT360649B/de active Protection Beyond IP Right Term
- 1978-06-06 PL PL1978207396A patent/PL114501B1/pl unknown
- 1978-06-06 IL IL54867A patent/IL54867A/xx unknown
- 1978-06-06 HU HU78PI630A patent/HU180042B/hu unknown
- 1978-06-06 PT PT68146A patent/PT68146A/pt unknown
- 1978-06-06 FI FI781800A patent/FI66003C/fi not_active IP Right Cessation
- 1978-06-06 IE IE1140/78A patent/IE47079B1/en not_active IP Right Cessation
- 1978-06-06 NL NLAANVRAGE7806126,A patent/NL180009C/xx not_active IP Right Cessation
- 1978-06-06 SE SE7806628A patent/SE436206B/sv not_active IP Right Cessation
- 1978-06-06 LU LU79774A patent/LU79774A1/fr unknown
- 1978-06-06 NO NO781970A patent/NO151746C/no unknown
- 1978-06-07 DD DD78218400A patent/DD148585A5/de unknown
- 1978-06-07 DD DD78205839A patent/DD140888A5/de unknown
- 1978-08-18 AR AR272228A patent/AR224111A1/es active
- 1978-09-08 PH PH21587A patent/PH16465A/en unknown
- 1978-09-08 PH PH21586A patent/PH21116A/en unknown
- 1978-09-19 FR FR787826789A patent/FR2393805A1/fr active Granted
1980
- 1980-03-07 AT AT0128580A patent/AT364084B/de not_active IP Right Cessation
1981
- 1981-02-19 IL IL62168A patent/IL62168A0/xx unknown
1982
- 1982-09-15 NO NO823126A patent/NO152448C/no unknown
1983
- 1983-10-27 SE SE8305916A patent/SE447995B/xx not_active IP Right Cessation
- 1983-11-02 SG SG653/83A patent/SG65383G/en unknown
- 1983-11-22 KE KE3355A patent/KE3355A/xx unknown
1984
- 1984-02-16 HK HK131/84A patent/HK13184A/xx not_active IP Right Cessation
1985
- 1985-12-30 MY MY92/85A patent/MY8500092A/xx unknown
1993
- 1993-06-11 NL NL930064C patent/NL930064I2/nl unknown

Also Published As

Publication number	Publication date
FR2393805B1 (xx)	1984-02-24
DK251478A (da)	1978-12-08
FR2393805A1 (fr)	1979-01-05
FI66003C (fi)	1984-08-10
HU180042B (en)	1983-01-28
DE2824535B2 (de)	1980-05-14
NL180009C (nl)	1986-12-16
YU117078A (en)	1983-01-21
KE3355A (en)	1983-12-16
IL54867A0 (en)	1978-08-31
PL207396A1 (pl)	1979-06-04
PH16465A (en)	1983-10-20
IN149747B (xx)	1982-04-03
AT364084B (de)	1981-09-25
AR224111A1 (es)	1981-10-30
NO152448B (no)	1985-06-24
NO152448C (no)	1985-10-02
IL62168A0 (en)	1981-03-31
DE2857263B2 (de)	1981-04-23
LU79774A1 (fr)	1980-01-22
GR72255B (xx)	1983-10-06
SU860706A1 (ru)	1981-08-30
DD148585A5 (de)	1981-06-03
FR2393804B1 (xx)	1980-11-07
SE8305916L (sv)	1983-10-27
NO823126L (no)	1978-12-08
DK155740B (da)	1989-05-08
DE2824535C3 (de)	1981-01-22
PL114501B1 (en)	1981-02-28
PT68146A (en)	1978-07-01
AU3683878A (en)	1979-12-06
DE2857263C3 (de)	1981-12-17
EG13869A (en)	1983-03-31
NZ187476A (en)	1982-08-17
OA05964A (fr)	1981-06-30
NL7806126A (nl)	1978-12-11
IL54867A (en)	1981-11-30
AU513636B2 (en)	1980-12-11
NL930064I1 (nl)	1993-09-01
ATA411278A (de)	1980-06-15
YU41829B (en)	1988-02-29
SE8305916D0 (sv)	1983-10-27
DD140888A5 (de)	1980-04-02
GB2000138A (en)	1979-01-04
FI66003B (fi)	1984-04-30
IT7824270A0 (it)	1978-06-06
FI781800A (fi)	1978-12-08
CH634073A5 (en)	1983-01-14
AT360649B (de)	1981-01-26
CS208472B2 (en)	1981-09-15
NO151746B (no)	1985-02-18
PH26810A (en)	1992-11-05
DE2824535A1 (de)	1978-12-14
SE436206B (sv)	1984-11-19
MY8500092A (en)	1985-12-31
FR2393804A1 (fr)	1979-01-05
NO151746C (no)	1985-06-05
NO781970L (no)	1978-12-08
SE447995B (sv)	1987-01-12
IT1096381B (it)	1985-08-26
HK13184A (en)	1984-02-24
GB2000138B (en)	1982-03-03
SG65383G (en)	1985-03-29
BE867859A (fr)	1978-12-06
ATA128580A (de)	1981-02-15
DK155740C (da)	1989-10-23
IE47079B1 (en)	1983-12-14
NL930064I2 (nl)	1994-04-18
IE781140L (en)	1978-12-07
BG34615A3 (en)	1983-10-15
SE7806628L (sv)	1978-12-08
PH21116A (en)	1987-07-16

Publication	Publication Date	Title
BG34614A3 (en)	1983-10-15	Method for preparing derivatives of penicillanic acid
BG33286A3 (en)	1983-01-14	Method for obtaining of 4- hydroxy- 2h- 1, 2- benzothiazin- 3- carboxamid- 1, 1- dioxides
BG34336A3 (en)	1983-08-15	Method for obtaining derivates of phtalazine-4-yl-acetic acid
BG31225A3 (en)	1981-11-16	Method for obtaining of acilanilid derivatives
BG28708A3 (en)	1980-06-16	Method of obtaining of imidazole derivatives
BG30015A3 (en)	1981-03-16	Method for obtaining of triphenylalkene derivatives
BG29132A3 (en)	1980-09-15	Method of obtaining of cyclohexan derivatives
BG35189A3 (en)	1984-02-15	Method for preparing derivatives of 6- beta- hydroxyalkylpenicillanic acid
BG34338A3 (en)	1983-08-15	Method for obtaining thiadiazolylcephalosporines
BG33294A3 (en)	1983-01-14	Method for obtaining the derivatives of 4- dezacetyl- vincaledcoblactine c- 3- carboxyhydrazid
BG28262A3 (en)	1980-03-25	Method of obtaining of 2,3- dinydroimidazo (2,1- b) thiazole derivatives
BG28573A3 (bg)	1980-05-15	Метод за получаване на аминоалкоксифенилови производни
BG33278A3 (en)	1983-01-14	Method for making of carbamide derivatives
BG30778A3 (en)	1981-08-14	Method for obtaining of eburnamenine derivatives
BG31073A3 (en)	1981-10-15	Method for obtaining of 1, 5- substituated- 2- pyrolidine
BG30927A3 (en)	1981-09-15	Method for obtaining of trans- 4- alpha- phenyl- octahydro- 1h- 2- pyridine
BG30176A4 (en)	1981-04-15	Method for obtaining of pyridinethion compounds
BG35466A3 (en)	1984-04-15	Method for preparing derivatives of clavulanic acid
BG28574A3 (en)	1980-05-15	Method of obtaining of 4- diphenylmethylene- 1- hydroxybensylpiperidin
BG30021A3 (en)	1981-03-16	Method for obtaining of imidazoisohinolin- dion
BG32116A3 (en)	1982-05-14	Method for obtaining of 4- amino- oleandomicine derivatives
BG28416A4 (en)	1980-04-15	Method of obtaining of benzo (c) hinolines
BG31947A3 (en)	1982-04-15	Method for obtaining of acetidine derivatives
BG35032A3 (en)	1984-01-16	Method for preparing 1, 1, 2- triphenylpropene derivatives
BG33283A3 (en)	1983-01-14	Method for obtaining of pyridazinylhydrazon