BE801006A - Synthese de l'acide n(5)-methyltetrahydrohomofolique et autres derives hydrogenes de l'acide homofolique - Google Patents
Synthese de l'acide n(5)-methyltetrahydrohomofolique et autres derives hydrogenes de l'acide homofoliqueInfo
- Publication number
- BE801006A BE801006A BE132349A BE132349A BE801006A BE 801006 A BE801006 A BE 801006A BE 132349 A BE132349 A BE 132349A BE 132349 A BE132349 A BE 132349A BE 801006 A BE801006 A BE 801006A
- Authority
- BE
- Belgium
- Prior art keywords
- acid
- hydrogenic
- synthesis
- derivatives
- methyltetrahydrohomofolic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US263559A US3870719A (en) | 1972-06-16 | 1972-06-16 | Synthesis of n-5-methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
BE801006A true BE801006A (fr) | 1973-10-01 |
Family
ID=23002269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE132349A BE801006A (fr) | 1972-06-16 | 1973-06-15 | Synthese de l'acide n(5)-methyltetrahydrohomofolique et autres derives hydrogenes de l'acide homofolique |
Country Status (19)
Country | Link |
---|---|
US (2) | US3870719A (xx) |
JP (1) | JPS5541234B2 (xx) |
AT (1) | AT329201B (xx) |
AU (1) | AU476569B2 (xx) |
BE (1) | BE801006A (xx) |
CA (1) | CA1004672A (xx) |
CH (1) | CH582178A5 (xx) |
CS (1) | CS169842B2 (xx) |
DE (1) | DE2330984A1 (xx) |
DK (1) | DK143028C (xx) |
FR (1) | FR2194708B1 (xx) |
GB (1) | GB1403850A (xx) |
HU (1) | HU166235B (xx) |
NL (1) | NL7307992A (xx) |
NO (1) | NO139890C (xx) |
PL (1) | PL89778B1 (xx) |
RO (1) | RO66639A (xx) |
SE (1) | SE404367B (xx) |
YU (1) | YU36958B (xx) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5124452A (en) * | 1978-07-10 | 1992-06-23 | Bioresearch S.P.A. | Process for producing d,1-5-methyltetrahydrofolic acid and its salts |
US5223500A (en) * | 1977-02-22 | 1993-06-29 | Bioresearch S.P.A. | Stable pharmaceutical composition of alkaline or alkaline earth 5-methyl tetrahydrofolate |
US4148999A (en) * | 1977-08-22 | 1979-04-10 | The Government Of The United States Of America | Preparation and purification of citrovorum factor |
US4665176A (en) * | 1984-10-23 | 1987-05-12 | Mitsui Toatsu Chemicals, Incorporated | Process for the preparation of 5,6,7,8-tetrahydrofolic acid |
WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2737515A (en) * | 1951-06-30 | 1956-03-06 | American Cyanamid Co | Salts of substituted tetrahydroformyl pteroyl amino acids |
US2790802A (en) * | 1954-05-06 | 1957-04-30 | American Cyanamid Co | Substituted tetrahydropteridines and method of preparing the same |
US3468886A (en) * | 1967-10-23 | 1969-09-23 | Us Health Education & Welfare | Tetrahydrohomofolic acid sulfate and synthesis thereof |
-
1972
- 1972-06-16 US US263559A patent/US3870719A/en not_active Expired - Lifetime
-
1973
- 1973-06-05 SE SE7307895A patent/SE404367B/xx unknown
- 1973-06-08 NL NL7307992A patent/NL7307992A/xx not_active Application Discontinuation
- 1973-06-08 AU AU56718/73A patent/AU476569B2/en not_active Expired
- 1973-06-12 HU HUHE633A patent/HU166235B/hu unknown
- 1973-06-13 YU YU1580/73A patent/YU36958B/xx unknown
- 1973-06-14 GB GB2840473A patent/GB1403850A/en not_active Expired
- 1973-06-15 FR FR7321806A patent/FR2194708B1/fr not_active Expired
- 1973-06-15 CS CS4336A patent/CS169842B2/cs unknown
- 1973-06-15 RO RO7375149A patent/RO66639A/ro unknown
- 1973-06-15 DK DK334073A patent/DK143028C/da not_active IP Right Cessation
- 1973-06-15 AT AT529073A patent/AT329201B/de not_active IP Right Cessation
- 1973-06-15 BE BE132349A patent/BE801006A/xx not_active IP Right Cessation
- 1973-06-15 CH CH869773A patent/CH582178A5/xx not_active IP Right Cessation
- 1973-06-15 CA CA174,120A patent/CA1004672A/en not_active Expired
- 1973-06-15 NO NO2499/73A patent/NO139890C/no unknown
- 1973-06-16 PL PL1973163402A patent/PL89778B1/pl unknown
- 1973-06-16 JP JP6736473A patent/JPS5541234B2/ja not_active Expired
- 1973-06-18 DE DE2330984A patent/DE2330984A1/de not_active Withdrawn
-
1974
- 1974-08-16 US US05/498,187 patent/US3983118A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATA529073A (de) | 1975-07-15 |
US3983118A (en) | 1976-09-28 |
GB1403850A (en) | 1975-08-28 |
RO66639A (ro) | 1982-05-10 |
NO139890C (no) | 1979-05-30 |
AT329201B (de) | 1976-04-26 |
AU5671873A (en) | 1974-12-12 |
FR2194708B1 (xx) | 1978-05-26 |
NL7307992A (xx) | 1973-12-18 |
US3870719A (en) | 1975-03-11 |
DK143028B (da) | 1981-03-16 |
DK143028C (da) | 1981-11-02 |
CA1004672A (en) | 1977-02-01 |
SE404367B (sv) | 1978-10-02 |
JPS4949992A (xx) | 1974-05-15 |
FR2194708A1 (xx) | 1974-03-01 |
NO139890B (no) | 1979-02-19 |
CS169842B2 (xx) | 1976-07-29 |
PL89778B1 (xx) | 1976-12-31 |
DE2330984A1 (de) | 1974-01-03 |
JPS5541234B2 (xx) | 1980-10-22 |
YU36958B (en) | 1984-08-31 |
HU166235B (xx) | 1975-02-28 |
YU158073A (en) | 1982-06-18 |
CH582178A5 (xx) | 1976-11-30 |
AU476569B2 (en) | 1976-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: GOUVERNEMENT DES ETATS-UNIS D AMERIQUE Effective date: 19840615 |