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NO139890C - Fremgangsmaate ved fremstilling av n5 -methyltetrahydrohomofolinsyre - Google Patents

Fremgangsmaate ved fremstilling av n5 -methyltetrahydrohomofolinsyre

Info

Publication number
NO139890C
NO139890C NO2499/73A NO249973A NO139890C NO 139890 C NO139890 C NO 139890C NO 2499/73 A NO2499/73 A NO 2499/73A NO 249973 A NO249973 A NO 249973A NO 139890 C NO139890 C NO 139890C
Authority
NO
Norway
Prior art keywords
procedure
preparation
methyltetrahydrohomofolic
acid
methyltetrahydrohomofolic acid
Prior art date
Application number
NO2499/73A
Other languages
English (en)
Other versions
NO139890B (no
Inventor
Roger Lyman Knott
Alison Taunton-Rigby
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Publication of NO139890B publication Critical patent/NO139890B/no
Publication of NO139890C publication Critical patent/NO139890C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO2499/73A 1972-06-16 1973-06-15 Fremgangsmaate ved fremstilling av n5 -methyltetrahydrohomofolinsyre NO139890C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US263559A US3870719A (en) 1972-06-16 1972-06-16 Synthesis of n-5-methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid

Publications (2)

Publication Number Publication Date
NO139890B NO139890B (no) 1979-02-19
NO139890C true NO139890C (no) 1979-05-30

Family

ID=23002269

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2499/73A NO139890C (no) 1972-06-16 1973-06-15 Fremgangsmaate ved fremstilling av n5 -methyltetrahydrohomofolinsyre

Country Status (19)

Country Link
US (2) US3870719A (no)
JP (1) JPS5541234B2 (no)
AT (1) AT329201B (no)
AU (1) AU476569B2 (no)
BE (1) BE801006A (no)
CA (1) CA1004672A (no)
CH (1) CH582178A5 (no)
CS (1) CS169842B2 (no)
DE (1) DE2330984A1 (no)
DK (1) DK143028C (no)
FR (1) FR2194708B1 (no)
GB (1) GB1403850A (no)
HU (1) HU166235B (no)
NL (1) NL7307992A (no)
NO (1) NO139890C (no)
PL (1) PL89778B1 (no)
RO (1) RO66639A (no)
SE (1) SE404367B (no)
YU (1) YU36958B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124452A (en) * 1978-07-10 1992-06-23 Bioresearch S.P.A. Process for producing d,1-5-methyltetrahydrofolic acid and its salts
US5223500A (en) * 1977-02-22 1993-06-29 Bioresearch S.P.A. Stable pharmaceutical composition of alkaline or alkaline earth 5-methyl tetrahydrofolate
US4148999A (en) * 1977-08-22 1979-04-10 The Government Of The United States Of America Preparation and purification of citrovorum factor
US4665176A (en) * 1984-10-23 1987-05-12 Mitsui Toatsu Chemicals, Incorporated Process for the preparation of 5,6,7,8-tetrahydrofolic acid
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2737515A (en) * 1951-06-30 1956-03-06 American Cyanamid Co Salts of substituted tetrahydroformyl pteroyl amino acids
US2790802A (en) * 1954-05-06 1957-04-30 American Cyanamid Co Substituted tetrahydropteridines and method of preparing the same
US3468886A (en) * 1967-10-23 1969-09-23 Us Health Education & Welfare Tetrahydrohomofolic acid sulfate and synthesis thereof

Also Published As

Publication number Publication date
ATA529073A (de) 1975-07-15
US3983118A (en) 1976-09-28
GB1403850A (en) 1975-08-28
RO66639A (ro) 1982-05-10
AT329201B (de) 1976-04-26
BE801006A (fr) 1973-10-01
AU5671873A (en) 1974-12-12
FR2194708B1 (no) 1978-05-26
NL7307992A (no) 1973-12-18
US3870719A (en) 1975-03-11
DK143028B (da) 1981-03-16
DK143028C (da) 1981-11-02
CA1004672A (en) 1977-02-01
SE404367B (sv) 1978-10-02
JPS4949992A (no) 1974-05-15
FR2194708A1 (no) 1974-03-01
NO139890B (no) 1979-02-19
CS169842B2 (no) 1976-07-29
PL89778B1 (no) 1976-12-31
DE2330984A1 (de) 1974-01-03
JPS5541234B2 (no) 1980-10-22
YU36958B (en) 1984-08-31
HU166235B (no) 1975-02-28
YU158073A (en) 1982-06-18
CH582178A5 (no) 1976-11-30
AU476569B2 (en) 1976-09-30

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