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BE1002937A5 - USE OF A NUCLEOBASE SOURCE FOR STIMULATION OF IMMUNE FUNCTION AND CORRESPONDING PHARMACEUTICAL AND FOOD COMPOSITIONS. - Google Patents

USE OF A NUCLEOBASE SOURCE FOR STIMULATION OF IMMUNE FUNCTION AND CORRESPONDING PHARMACEUTICAL AND FOOD COMPOSITIONS. Download PDF

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Publication number
BE1002937A5
BE1002937A5 BE8900260A BE8900260A BE1002937A5 BE 1002937 A5 BE1002937 A5 BE 1002937A5 BE 8900260 A BE8900260 A BE 8900260A BE 8900260 A BE8900260 A BE 8900260A BE 1002937 A5 BE1002937 A5 BE 1002937A5
Authority
BE
Belgium
Prior art keywords
stimulation
immune function
nucleobase
food compositions
corresponding pharmaceutical
Prior art date
Application number
BE8900260A
Other languages
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Application granted granted Critical
Publication of BE1002937A5 publication Critical patent/BE1002937A5/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention porte sur l'utilisation d'une source de nucléobase pour la stimulation de la fonction immunitaire dans le corps humain ou animal, ladite source de nucléobase se présentant sous la forme d'une composition alimentaire ou pharmaceutique. Des sources de nucléobase appropriées sont essentiellement constituées par des nucléobases, nucléosides, nucléotides, ARN, ADN naturels, leurs équivalents et/ou des mélanges comprenant un ou plusieurs de ces composés. Le procédé et les compositions de l'invention peuvent être employées dans tous les cas où une stimulation de la fonction immunitaire est souhaitable.The invention relates to the use of a nucleobase source for the stimulation of the immune function in the human or animal body, said nucleobase source being in the form of a food or pharmaceutical composition. Suitable nucleobase sources consist essentially of nucleobases, nucleosides, nucleotides, RNA, natural DNA, their equivalents and / or mixtures comprising one or more of these compounds. The method and compositions of the invention can be used in all cases where stimulation of the immune function is desirable.

BE8900260A 1988-03-11 1989-03-10 USE OF A NUCLEOBASE SOURCE FOR STIMULATION OF IMMUNE FUNCTION AND CORRESPONDING PHARMACEUTICAL AND FOOD COMPOSITIONS. BE1002937A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16686688A 1988-03-11 1988-03-11

Publications (1)

Publication Number Publication Date
BE1002937A5 true BE1002937A5 (en) 1991-09-03

Family

ID=22604997

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8900260A BE1002937A5 (en) 1988-03-11 1989-03-10 USE OF A NUCLEOBASE SOURCE FOR STIMULATION OF IMMUNE FUNCTION AND CORRESPONDING PHARMACEUTICAL AND FOOD COMPOSITIONS.

Country Status (9)

Country Link
JP (1) JPH01279835A (en)
BE (1) BE1002937A5 (en)
CH (1) CH681203A5 (en)
DE (1) DE3907842A1 (en)
FR (1) FR2628320A1 (en)
GB (1) GB2216416B (en)
IT (1) IT1232819B (en)
NL (1) NL8900581A (en)
SE (1) SE8900835L (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2529605B2 (en) * 1989-10-23 1996-08-28 株式会社大塚製薬工場 Immunostimulant
US5492899A (en) * 1994-01-10 1996-02-20 Abbott Laboratories Infant nutritional formula with ribo-nucleotides
US6136858A (en) 1994-01-10 2000-10-24 Abbott Laboratories Infant formula and methods of improving infant stool patterns
US5488039A (en) * 1994-01-10 1996-01-30 Abbott Laboratories Method for the production of an enteral formula containing ribo-nucleotides
US5602109A (en) * 1994-01-10 1997-02-11 Abbott Laboratories Method to enhance the immune system of a human
US5700590A (en) * 1994-01-10 1997-12-23 Abbott Laboratories Nutritional formula with ribo-nucleotides
US20030026782A1 (en) 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6706691B1 (en) 1998-07-15 2004-03-16 Board Of Regents, The University Of Texas System Immunosupportive drug sparing diet
ES2219182B1 (en) * 2003-05-12 2005-10-01 Jose Luis Concellon Martinez PROCEDURE TO COMPENSATE THE NEGATIVE EFFECT ON HEALTH OF FOODS THAT CONTAIN REFINED SUGAR.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154397A1 (en) * 1971-04-08 1973-05-11 Erba Carlo Spa Nutritive milk additive - to simulate mother's milk contains a high content of nucleic acids
EP0107161A2 (en) * 1982-10-26 1984-05-02 CTA Finanz AG Device and process for optimising the tissue mass of organs within the genetic fluctuation range in humans and animals

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
JPS385291B1 (en) * 1960-09-07 1963-05-07
SE302878B (en) * 1960-12-29 1968-08-05 Takeda Chemical Industries Ltd
IL29066A (en) * 1966-12-23 1972-11-28 Merck & Co Inc Pharmaceutical compositions containing multistranded polynucleotides for inducing formation of interferon in persons or animals or in cell cultures
DE1617545C2 (en) * 1967-06-19 1983-11-03 Diether Prof. Dr. Bern Jachertz Use of informational ribonucleic acid as a vaccine
GB1254744A (en) * 1969-06-19 1971-11-24 Beecham Group Ltd Antiviral ribonucleic acid substance
DE1941942A1 (en) * 1969-08-18 1971-03-04 Sylven Bengt Prof Dr New pharmaceutical agent
US3914450A (en) * 1973-04-09 1975-10-21 Anheuser Busch Concentrated extract of yeast and processes of making same
GB1363398A (en) * 1973-03-29 1974-08-14 Yamasa Shoyu Kk Uridine-5.-monophosphate compositions
FR2353293A1 (en) * 1976-06-03 1977-12-30 Beljanski Mirko POLYRIBONUCLEOTIDES WITH AN ACTIVITY IN THE GENESIS OF LEUCOCYTES AND BLOOD PLATELETS
FR2374911A1 (en) * 1976-12-21 1978-07-21 Fabre Sa Pierre NON-SPECIFIC IMMUNITY ADJUVANTS
FR2471785A1 (en) * 1979-12-21 1981-06-26 Fabre Sa Pierre RIBOSOMAL RNA-BASED IMMUNOSTIMULANT PREPARATIONS AND PROCESS FOR THE PREPARATION OF RNA
US4643992A (en) * 1982-11-09 1987-02-17 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
JPS59219235A (en) * 1983-05-30 1984-12-10 Mitsui Toatsu Chem Inc Drug for peptic ulcer
JPS608307A (en) * 1983-06-28 1985-01-17 Ube Ind Ltd Production of reinforced polybutadiene
JPS60126220A (en) * 1983-12-09 1985-07-05 Otsuka Pharmaceut Factory Inc Nucleic acid component composition
EP0196530A3 (en) * 1985-03-26 1989-03-22 CTA Finanz AG Agent and process for increasing growth, for optimizing fertility and for stimulating the immune system in humans and animals
JPH0669953B2 (en) * 1985-08-16 1994-09-07 日産化学工業株式会社 Cerebrospinal system neurotrophic agent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2154397A1 (en) * 1971-04-08 1973-05-11 Erba Carlo Spa Nutritive milk additive - to simulate mother's milk contains a high content of nucleic acids
EP0107161A2 (en) * 1982-10-26 1984-05-02 CTA Finanz AG Device and process for optimising the tissue mass of organs within the genetic fluctuation range in humans and animals

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ADV. EXP. MED. BIOL., vol. 165, partie B, 1984, pages 175-178; F.B. RUDOLPH et al.: "Involvement of dietary nucleotides in T lymphocyte function" *
ADV. EXP. MED. BIOL., vol. 195A, no.: Pyrimidine Metab. Man 5, pt. A, 1986, pages 497-501; F.B. RUDOLPH et al.: "Effect of dietary nucleotides on lymphocyte maturation" *
ARCH. SURG., vol. 121, no. 2, février 1986, pages 169-172; A.D. KULKARNI et al.: "Influence of dietary nucleotide restriction on bacterial sepsis and phagocytic cell function in mice" *
CHEMICAL ABSTRACTS, vol. 104, no. 23, 9 juin 1986, page 645, abrégé no. 206041p, Columbus, Ohio, US; A.D. KULKARNI et al.: "Effect of dietary nucleotides on response to bacterial infections", & J. PARENTER. ENTERAL NUTR. 1986, 10(2), 169-71 *
CHEMICAL ABSTRACTS, vol. 108, no. 9, 29 février 1988, page 530, abrégé no. 73587e, Columbus, Ohio, US; A.D. KULKARNI et al.: "Modulation of delayed hypersensitivity in mice by dietary nucleotide restriction", & TRANSPLANTATION 1987, 44(6), 847-9 *
J.E.F. REYNOLDS: "Martindale, the extra pharmacopoeia", edition 28, 1982, The Pharmaceutical Press, London, GB *
TRANSPLANTATION PROCEEDINGS, vol. XIX, no. 4, suppl. 5 août 1987, pages 57-59; C.T. VAN BUREN et al.: "Nucleotide-free diet and suppression of immune response" *

Also Published As

Publication number Publication date
GB2216416B (en) 1992-06-24
SE8900835L (en) 1989-09-12
GB8905179D0 (en) 1989-04-19
IT1232819B (en) 1992-03-05
DE3907842A1 (en) 1989-09-21
FR2628320A1 (en) 1989-09-15
IT8947733A0 (en) 1989-03-10
NL8900581A (en) 1989-10-02
SE8900835D0 (en) 1989-03-09
JPH01279835A (en) 1989-11-10
CH681203A5 (en) 1993-02-15
GB2216416A (en) 1989-10-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM

Effective date: 19960331