BA98302A - Bis-aza-biciklicna anksioliticka sredstva - Google Patents

Bis-aza-biciklicna anksioliticka sredstva

Info

Publication number: BA98302A
Authority: BA; Bosnia and Herzegovina
Prior art keywords: aza; bis; anxiolytic agents; bicyclic; bicyclic anxiolytic
Prior art date: 1989-01-23

Application number

BA980302A

Other languages

English (en)

Inventor

Gene Michael Bright

Kishor Amratral Desai

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-23

Filing date

1998-03-30

Publication date

2001-09-14

1998-03-30 Application filed by Pfizer filed Critical Pfizer

2001-09-14 Publication of BA98302A publication Critical patent/BA98302A/bs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

BA980302A 1989-01-23 1998-03-30 Bis-aza-biciklicna anksioliticka sredstva BA98302A (bs)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
PCT/US1989/000275 WO1990008148A1 (en)	1989-01-23	1989-01-23	Bis-aza-bicyclic anxiolytic agents
PCT/US1989/003811 WO1990008144A1 (en)	1989-01-23	1989-09-01	Bis-aza-bicyclic anxiolytic agents
YU11190A YU47554B (sh)	1989-01-23	1990-01-22	RACEMSKI I OPTIČKI AKTIVNI DERIVATI PIRIDO (1,2-a) PIRAZINA I NJIHOVI INTERMEDIJERI

Publications (1)

Publication Number	Publication Date
BA98302A true BA98302A (bs)	2001-09-14

Family

ID=22214801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BA980302A BA98302A (bs)	1989-01-23	1998-03-30	Bis-aza-biciklicna anksioliticka sredstva

Country Status (38)

Country	Link
US (1)	US5122525A (bs)
EP (1)	EP0380217B1 (bs)
JP (1)	JPH0643427B2 (bs)
KR (1)	KR910009289B1 (bs)
CN (1)	CN1022186C (bs)
AP (1)	AP128A (bs)
AR (1)	AR246969A1 (bs)
AT (1)	ATE82574T1 (bs)
AU (1)	AU614214B2 (bs)
BA (1)	BA98302A (bs)
BG (1)	BG51046A3 (bs)
CA (1)	CA2008108C (bs)
CZ (1)	CZ277698B6 (bs)
DD (1)	DD291560A5 (bs)
DE (1)	DE69000467T2 (bs)
DK (1)	DK0380217T3 (bs)
EG (1)	EG19306A (bs)
ES (1)	ES2053094T3 (bs)
FI (1)	FI95381C (bs)
GR (1)	GR3006925T3 (bs)
HU (1)	HU215154B (bs)
IE (1)	IE62670B1 (bs)
IL (1)	IL93073A (bs)
IS (1)	IS1667B (bs)
MA (1)	MA21735A1 (bs)
MX (1)	MX19222A (bs)
MY (1)	MY104861A (bs)
NO (1)	NO175978C (bs)
NZ (1)	NZ232168A (bs)
OA (1)	OA10041A (bs)
PL (1)	PL163836B1 (bs)
PT (1)	PT92919B (bs)
RO (1)	RO110142B1 (bs)
RU (1)	RU2015977C1 (bs)
SK (1)	SK279339B6 (bs)
WO (2)	WO1990008148A1 (bs)
YU (1)	YU47554B (bs)
ZA (1)	ZA90430B (bs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX19222A (es) *	1989-01-23	1993-12-01	Pfizer	Agentes ansioliticos bis-aza-biciclicos
WO1992000075A1 (en) *	1990-06-29	1992-01-09	Pfizer Inc.	Pyridopyrazine derivatives for treating substance abuse and addiction
DE69108743T2 (de) *	1991-01-31	1995-08-17	Pfizer	Recematspaltung von trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]-pyrazin.
US5157034A (en) *	1991-02-27	1992-10-20	Pfizer Inc.	Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
DK0573464T3 (da) *	1991-02-27	1997-09-01	Pfizer	Fremgangsmåde til fremstilling af trans-piperidin-2,5-dicarboxylater
US5185449A (en) *	1991-02-27	1993-02-09	Pfizer Inc.	Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
US5311195A (en) *	1991-08-30	1994-05-10	Etak, Inc.	Combined relative and absolute positioning method and apparatus
US5565453A (en) *	1991-09-25	1996-10-15	Pfizer Inc.	Neuroleptic 2-substituted perhydro-1-h-pyrido[1,2-a]pyrazines
WO1993025552A1 (en) *	1992-06-16	1993-12-23	Pfizer Inc.	Process and intermediates for bis-aza-bicyclic anxiolytic agents
WO1994006794A1 (en) *	1992-09-24	1994-03-31	National Institutes Of Health	Aralkyl diazabicycloalkane derivatives for cns disorders
IL104506A (en) *	1993-01-25	1997-11-20	Israel State	Fast changing heating- cooling device and method, particularly for cryogenic and/or surgical use
US5637713A (en) *	1993-08-20	1997-06-10	Pfizer Inc.	Process for preparing trans-piperidine-2,5-dicarboxylates
US5455350A (en) *	1993-10-13	1995-10-03	Pfizer Inc.	Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
IL107460A (en) *	1993-11-01	1999-06-20	Israel State	Controlled cryogenic contact system
US5731307A (en) *	1994-09-30	1998-03-24	Pfizer, Inc.	Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
US6231833B1 (en)	1999-08-05	2001-05-15	Pfizer Inc	2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
PT783503E (pt) *	1994-09-30	2002-03-28	Pfizer	Derivados de octa-hidro-1h-pirido¬1,2-a\|pirazina 2,7-substituida
PL327539A1 (en) *	1995-12-21	1998-12-21	Pfizer	2,7-substituted derivatives of octahydropyrrole[1,2-a]-pyrazine
JPH11512751A (ja) *	1996-07-01	1999-11-02	ファイザー・インク	（７ｓ，トランス）―２―（２―ピリミジニル）―７―（ヒドロキシメチル）オクタヒドロ―２Ｈ―ピリド［１，２―Ａ］ピラジンの製造
PA8469101A1 (es) *	1998-04-09	2000-09-29	Pfizer Prod Inc	Ligandos azabiciclicos de receptores 5ht1
US6251893B1 (en) *	1998-06-15	2001-06-26	Nps Allelix Corp.	Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
HN1999000146A (es) *	1998-09-21	2000-11-11	Pfizer Prod Inc	Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.
US20020016334A1 (en) *	2000-07-31	2002-02-07	Coe Jotham Wadsworth	Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD)
US6670476B2 (en)	2000-11-29	2003-12-30	Pfizer Inc.	Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
EP1608648B1 (en) *	2003-03-12	2012-07-18	Pfizer Products Inc.	Pyridyloxymethyl and benzisoxazole azabicyclic derivatives
ATE418555T1 (de)	2003-04-09	2009-01-15	Biogen Idec Inc	A2a-adenosinrezeptorantagonisten
DK1689721T3 (da) *	2003-11-26	2010-09-20	Pfizer Prod Inc	Aminopyrazolderivater som GSK-3-ihibitorer
CA2566154A1 (en) *	2004-05-27	2005-12-08	Warner-Lambert Company Llc	Combination of atomoxetine and a 5t1a receptor agonist for treating adhd and other disorders
US7658206B2 (en)	2006-12-05	2010-02-09	Kohler Co.	Plumbing valve with stick control handle

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3388128A (en) *	1965-09-03	1968-06-11	Allan R. Day	Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
US4182763A (en) *	1978-05-22	1980-01-08	Mead Johnson & Company	Buspirone anti-anxiety method
US4339579A (en) *	1980-12-29	1982-07-13	American Home Products Corporation	2,6-Bis-(pyrrolopyrazinyl)pyrazines
US4400511A (en) *	1982-05-07	1983-08-23	American Home Products Corporation	2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids
US4414389A (en) *	1982-05-25	1983-11-08	American Home Products Corporation	4-Substituted-piperidino carboxamides
US4517187A (en) *	1982-10-18	1985-05-14	Pennwalt Corporation	1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
DE3321969A1 (de) *	1983-06-18	1984-12-20	Troponwerke GmbH & Co KG, 5000 Köln	2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3409440A1 (de) *	1984-03-15	1985-09-26	Bayer Ag, 5090 Leverkusen	Imidazo(1,5-a)pyridyl-methan- und imidazo(1,5-b)pyridazinylmethan-derivate, ihre herstellung und sie enthaltende aufzeichnungsmaterialien
IT1204803B (it) *	1986-02-17	1989-03-10	Acraf	Composto farmacologicamente attivo e composizioni farmaceutiche che lo contengono,procedimento per prepararlo e intermedio utile in detto procedimento
US4788290A (en) *	1987-12-11	1988-11-29	American Home Products Corporation	Serotonergic pyrazine derivatives
JP2668259B2 (ja) *	1988-02-18	1997-10-27	塩野義製薬株式会社	複素環化合物および抗潰瘍剤
MX19222A (es) *	1989-01-23	1993-12-01	Pfizer	Agentes ansioliticos bis-aza-biciclicos

1989
- 1989-01-23 MX MX1922290A patent/MX19222A/es unknown
- 1989-01-23 WO PCT/US1989/000275 patent/WO1990008148A1/en unknown
- 1989-09-01 HU HU40/90A patent/HU215154B/hu not_active IP Right Cessation
- 1989-09-01 WO PCT/US1989/003811 patent/WO1990008144A1/en active IP Right Grant
- 1989-09-01 RO RO148053A patent/RO110142B1/ro unknown
- 1989-12-13 IS IS3529A patent/IS1667B/is unknown
1990
- 1990-01-12 DE DE9090300362T patent/DE69000467T2/de not_active Expired - Fee Related
- 1990-01-12 DK DK90300362.2T patent/DK0380217T3/da active
- 1990-01-12 EP EP90300362A patent/EP0380217B1/en not_active Expired - Lifetime
- 1990-01-12 ES ES90300362T patent/ES2053094T3/es not_active Expired - Lifetime
- 1990-01-12 AT AT90300362T patent/ATE82574T1/de not_active IP Right Cessation
- 1990-01-16 IL IL9307390A patent/IL93073A/en not_active IP Right Cessation
- 1990-01-18 BG BG090949A patent/BG51046A3/xx unknown
- 1990-01-19 AR AR90315971A patent/AR246969A1/es active
- 1990-01-19 MY MYPI90000101A patent/MY104861A/en unknown
- 1990-01-19 CA CA002008108A patent/CA2008108C/en not_active Expired - Fee Related
- 1990-01-19 NZ NZ232168A patent/NZ232168A/xx unknown
- 1990-01-21 EG EG3290A patent/EG19306A/xx active
- 1990-01-22 SK SK299-90A patent/SK279339B6/sk unknown
- 1990-01-22 YU YU11190A patent/YU47554B/sh unknown
- 1990-01-22 MA MA21996A patent/MA21735A1/fr unknown
- 1990-01-22 CN CN90100291A patent/CN1022186C/zh not_active Expired - Fee Related
- 1990-01-22 CZ CS90299A patent/CZ277698B6/cs not_active IP Right Cessation
- 1990-01-22 PT PT92919A patent/PT92919B/pt not_active IP Right Cessation
- 1990-01-22 AP APAP/P/1990/000158A patent/AP128A/en active
- 1990-01-22 ZA ZA90430A patent/ZA90430B/xx unknown
- 1990-01-22 PL PL90283395A patent/PL163836B1/pl not_active IP Right Cessation
- 1990-01-22 KR KR1019900000701A patent/KR910009289B1/ko not_active IP Right Cessation
- 1990-01-22 AU AU48679/90A patent/AU614214B2/en not_active Ceased
- 1990-01-22 DD DD90337249A patent/DD291560A5/de not_active IP Right Cessation
- 1990-01-22 IE IE22590A patent/IE62670B1/en not_active IP Right Cessation
- 1990-01-23 JP JP2013459A patent/JPH0643427B2/ja not_active Expired - Fee Related
- 1990-01-23 OA OA59727A patent/OA10041A/en unknown
1991
- 1991-07-09 US US07/721,537 patent/US5122525A/en not_active Expired - Lifetime
- 1991-07-22 RU SU915001279A patent/RU2015977C1/ru not_active IP Right Cessation
- 1991-07-22 NO NO912863A patent/NO175978C/no unknown
- 1991-07-22 FI FI913510A patent/FI95381C/fi not_active IP Right Cessation
1993
- 1993-01-28 GR GR930400172T patent/GR3006925T3/el unknown
1998
- 1998-03-30 BA BA980302A patent/BA98302A/bs unknown

Also Published As

Publication number	Publication date
EG19306A (en)	1995-01-31
DE69000467D1 (de)	1992-12-24
IL93073A (en)	1994-05-30
GR3006925T3 (bs)	1993-06-30
FI913510A0 (fi)	1991-07-22
CZ277698B6 (en)	1993-03-17
ATE82574T1 (de)	1992-12-15
YU11190A (sh)	1993-05-28
IE900225L (en)	1990-07-23
PT92919A (pt)	1990-07-31
FI95381B (fi)	1995-10-13
IE62670B1 (en)	1995-03-08
CA2008108C (en)	1995-08-08
RO110142B1 (ro)	1995-10-30
MX19222A (es)	1993-12-01
YU47554B (sh)	1995-10-03
DE69000467T2 (de)	1993-04-01
NZ232168A (en)	1991-08-27
JPH02233681A (ja)	1990-09-17
HUT63163A (en)	1993-07-28
WO1990008148A1 (en)	1990-07-26
AR246969A1 (es)	1994-10-31
MY104861A (en)	1994-06-30
EP0380217A1 (en)	1990-08-01
NO912863D0 (no)	1991-07-22
AU614214B2 (en)	1991-08-22
DD291560A5 (de)	1991-07-04
WO1990008144A1 (en)	1990-07-26
IS1667B (is)	1997-11-14
NO912863L (no)	1991-07-22
EP0380217B1 (en)	1992-11-19
KR900011774A (ko)	1990-08-02
ZA90430B (en)	1991-08-28
US5122525A (en)	1992-06-16
FI95381C (fi)	1996-01-25
OA10041A (en)	1996-10-14
CN1022186C (zh)	1993-09-22
MA21735A1 (fr)	1990-10-01
DK0380217T3 (da)	1992-12-14
CA2008108A1 (en)	1990-07-23
KR910009289B1 (ko)	1991-11-09
CS29990A3 (en)	1992-11-18
NO175978C (no)	1995-01-11
JPH0643427B2 (ja)	1994-06-08
ES2053094T3 (es)	1994-07-16
AP128A (en)	1991-03-20
RU2015977C1 (ru)	1994-07-15
SK279339B6 (sk)	1998-10-07
NO175978B (no)	1994-10-03
AU4867990A (en)	1990-07-26
AP9000158A0 (en)	1990-01-31
HU215154B (hu)	2000-09-28
PL163836B1 (pl)	1994-05-31
PT92919B (pt)	1995-12-29
CN1044464A (zh)	1990-08-08
IS3529A7 (is)	1990-07-24
BG51046A3 (en)	1993-01-15

Publication	Publication Date	Title
BA98302A (bs)	2001-09-14	Bis-aza-biciklicna anksioliticka sredstva
BR9002634A (pt)	1991-08-20	Poli-alfa-olefina
BR9000014A (pt)	1990-10-09	Classificaodr
DD294367A5 (de)	1991-09-26	Farbbildroehre
BR9001818A (pt)	1991-11-12	Girotrom quase-otico
ATA149789A (de)	1992-04-15	Schienenrad
DE59010414D1 (de)	1996-08-14	Fluorphenylpyridine
DD284561A5 (de)	1990-11-14	Chiptraeger
BR9006503A (pt)	1991-10-01	Copolimero agrilamidios
BR8906629A (pt)	1991-06-18	Transgui ii
BR8902801A (pt)	1990-12-26	Vesete
BR8900468A (pt)	1990-05-29	Base-arquivo
BR8906628A (pt)	1991-06-18	Chin-car
BR8906438A (pt)	1991-06-11	Super-domino
BR8906303A (pt)	1991-06-04	Fleximetro
BR8906265A (pt)	1991-06-04	Aspersorio
BR8905416A (pt)	1991-04-23	Continuador
BR8905026A (pt)	1991-04-30	Babadouro multiutilitario
BR8904521A (pt)	1991-03-05	Arquinho
BR8904228A (pt)	1989-11-28	Saia-abajur
BR8904110A (pt)	1991-02-19	Subsolador
BR8903923A (pt)	1991-02-05	Form-facil
BR8902938A (pt)	1990-12-04	Letramatica
DE3991666T1 (de)	1991-04-25	Glaettbohrer
BR8902705A (pt)	1990-12-26	Carrepipa