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AU529328B2 - Alphatic and cycloaliphatic amides and hydrazides - Google Patents

Alphatic and cycloaliphatic amides and hydrazides

Info

Publication number
AU529328B2
AU529328B2 AU43233/79A AU4323379A AU529328B2 AU 529328 B2 AU529328 B2 AU 529328B2 AU 43233/79 A AU43233/79 A AU 43233/79A AU 4323379 A AU4323379 A AU 4323379A AU 529328 B2 AU529328 B2 AU 529328B2
Authority
AU
Australia
Prior art keywords
alphatic
hydrazides
cycloaliphatic
amides
cycloaliphatic amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU43233/79A
Other versions
AU4323379A (en
Inventor
John G. Heider
Faizulla Gulamhusein Kathawala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,780 external-priority patent/US4229463A/en
Priority claimed from US05/891,298 external-priority patent/US4194002A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU4323379A publication Critical patent/AU4323379A/en
Application granted granted Critical
Publication of AU529328B2 publication Critical patent/AU529328B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B22/00Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
    • C04B22/0013Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ceramic Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU43233/79A 1978-01-09 1979-01-09 Alphatic and cycloaliphatic amides and hydrazides Ceased AU529328B2 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US86782478A 1978-01-09 1978-01-09
US86781378A 1978-01-09 1978-01-09
US87283678A 1978-01-27 1978-01-27
US88178178A 1978-02-27 1978-02-27
US881781 1978-02-27
US05/881,780 US4229463A (en) 1978-02-27 1978-02-27 Unsaturated fatty acid hydrazides
US881780 1978-02-27
US05/891,298 US4194002A (en) 1978-03-29 1978-03-29 Cholesterol ester-reducing amides of hexahydroindolinols
US891298 1978-03-29
US867824 1986-05-27
US867813 1992-04-13
US872836 1997-06-11

Publications (2)

Publication Number Publication Date
AU4323379A AU4323379A (en) 1979-07-19
AU529328B2 true AU529328B2 (en) 1983-06-02

Family

ID=27560330

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43233/79A Ceased AU529328B2 (en) 1978-01-09 1979-01-09 Alphatic and cycloaliphatic amides and hydrazides

Country Status (20)

Country Link
JP (1) JPS54109930A (en)
AU (1) AU529328B2 (en)
CA (1) CA1101871A (en)
CH (1) CH644842A5 (en)
CY (1) CY1294A (en)
DE (1) DE2856856A1 (en)
DK (1) DK3079A (en)
FI (1) FI790025A (en)
FR (1) FR2416885A1 (en)
GB (1) GB2012261B (en)
HK (1) HK80985A (en)
IE (1) IE48077B1 (en)
IL (1) IL56393A (en)
IT (1) IT1110603B (en)
KE (1) KE3546A (en)
MY (1) MY8500133A (en)
NZ (1) NZ189331A (en)
PT (1) PT69052A (en)
SE (1) SE446093B (en)
SG (1) SG42985G (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937175A1 (en) * 1978-09-18 1980-03-27 Sandoz Ag SECOND AMIDES OF 2-ALKYNOYL ACIDS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL COMPOSITIONS
US4297349A (en) 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
FR2633617B1 (en) * 1988-07-04 1991-02-08 Adir NOVEL BENZOCYCLOHEPTENE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
AU2009239430B2 (en) * 2008-04-21 2015-01-22 Signum Biosciences, Inc. Compounds, compositions and methods for making the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1814334B2 (en) * 1967-12-21 1973-04-19 Sumitomo Chemical Co Ltd , Osaka (Japan) FATTY ACID AMIDES AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
FR2000945A1 (en) * 1968-01-30 1969-09-19 Sumitomo Chemical Co
JPS5835505B2 (en) * 1976-01-09 1983-08-03 エーザイ株式会社 N-(α-methyl-benzyl)-fatty acid amide

Also Published As

Publication number Publication date
IE790031L (en) 1979-07-09
AU4323379A (en) 1979-07-19
FR2416885B1 (en) 1983-04-22
SG42985G (en) 1985-12-13
NZ189331A (en) 1981-07-13
GB2012261B (en) 1982-12-22
IT7919059A0 (en) 1979-01-04
JPS6323987B2 (en) 1988-05-18
SE7900142L (en) 1979-07-10
JPS54109930A (en) 1979-08-29
CY1294A (en) 1985-10-18
FI790025A (en) 1979-07-10
KE3546A (en) 1985-07-19
MY8500133A (en) 1985-12-31
DE2856856A1 (en) 1979-07-12
DK3079A (en) 1979-07-10
PT69052A (en) 1979-02-01
HK80985A (en) 1985-10-25
IL56393A0 (en) 1979-03-12
CH644842A5 (en) 1984-08-31
IL56393A (en) 1982-08-31
CA1101871A (en) 1981-05-26
GB2012261A (en) 1979-07-25
IE48077B1 (en) 1984-09-19
IT1110603B (en) 1985-12-23
SE446093B (en) 1986-08-11
FR2416885A1 (en) 1979-09-07

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