[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AU2007333737A1 - Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides - Google Patents

Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides Download PDF

Info

Publication number
AU2007333737A1
AU2007333737A1 AU2007333737A AU2007333737A AU2007333737A1 AU 2007333737 A1 AU2007333737 A1 AU 2007333737A1 AU 2007333737 A AU2007333737 A AU 2007333737A AU 2007333737 A AU2007333737 A AU 2007333737A AU 2007333737 A1 AU2007333737 A1 AU 2007333737A1
Authority
AU
Australia
Prior art keywords
substituted
alkylene
alkyl
group
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007333737A
Other languages
English (en)
Inventor
Junjie Liu
Zhenwei Miao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ambrx Inc
Original Assignee
Ambrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc filed Critical Ambrx Inc
Publication of AU2007333737A1 publication Critical patent/AU2007333737A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
AU2007333737A 2006-12-18 2007-12-18 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides Abandoned AU2007333737A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87059406P 2006-12-18 2006-12-18
US60/870,594 2006-12-18
PCT/US2007/088011 WO2008077079A1 (en) 2006-12-18 2007-12-18 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

Publications (1)

Publication Number Publication Date
AU2007333737A1 true AU2007333737A1 (en) 2008-06-26

Family

ID=39536734

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007333737A Abandoned AU2007333737A1 (en) 2006-12-18 2007-12-18 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

Country Status (8)

Country Link
EP (1) EP2079687A1 (ko)
JP (1) JP2010512800A (ko)
KR (1) KR20090100407A (ko)
CN (1) CN101578264A (ko)
AU (1) AU2007333737A1 (ko)
CA (1) CA2672205A1 (ko)
MX (1) MX2009006617A (ko)
WO (2) WO2011028195A2 (ko)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2370473B1 (en) * 2008-12-10 2016-05-11 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
WO2010096394A2 (en) 2009-02-17 2010-08-26 Redwood Biosciences, Inc. Aldehyde-tagged protein-based drug carriers and methods of use
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
NZ607069A (en) 2010-08-17 2014-10-31 Ambrx Inc Modified relaxin polypeptides and their uses
WO2012097333A2 (en) 2011-01-14 2012-07-19 Redwood Bioscience, Inc. Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
EP2820030A4 (en) * 2012-02-29 2015-04-15 Ambrx Inc INTERLEUKIN-3-POLYPEPTIDE CONJUGATES AND ITS USES
CN104244989A (zh) * 2012-02-29 2014-12-24 Ambrx公司 含有新颖前药的分子组合物和其用途
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
SG11201408153YA (en) * 2012-06-07 2015-01-29 Ambrx Inc Prostate-specific membrane antigen antibody drug conjugates
CA2877124A1 (en) * 2012-06-19 2013-12-27 Ambrx, Inc. Anti-cd70 antibody drug conjugates
EP2968552B1 (en) 2013-03-14 2020-03-11 The Scripps Research Institute Targeting agent antibody conjugates and uses thereof
EP2970177A1 (en) 2013-03-15 2016-01-20 Pfizer Inc. Indole compounds that activate ampk
WO2015057834A1 (en) 2013-10-15 2015-04-23 The California Institute For Biomedical Research Peptidic chimeric antigen receptor t cell switches and uses thereof
WO2016154621A1 (en) 2015-03-26 2016-09-29 The California Institute For Biomedical Research SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
US11091546B2 (en) 2015-04-15 2021-08-17 The Scripps Research Institute Optimized PNE-based chimeric receptor T cell switches and uses thereof
JP2019515677A (ja) 2016-04-26 2019-06-13 アール．ピー．シェーラー テクノロジーズ エルエルシー 抗体複合体ならびにそれを作製および使用する方法
AU2017345479B2 (en) 2016-10-19 2024-03-21 The Scripps Research Institute Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
EP3580232B1 (en) 2017-02-08 2023-09-20 Bristol-Myers Squibb Company Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
KR20210057124A (ko) 2018-09-11 2021-05-20 암브룩스, 인코포레이티드 인터류킨-2 폴리펩타이드 접합체 및 그의 용도
EP3970208A4 (en) * 2019-05-13 2023-07-26 Shanghai Polaris Biology Co., Ltd. LABEL FOR MARKING BIOMOLECULES
CN114524934B (zh) * 2020-11-23 2024-01-30 华东理工大学 多肽聚合物或多肽模拟物在骨修复中的应用
EP4368722A1 (en) * 2021-07-07 2024-05-15 Ajinomoto Co., Inc. Method for secretory production of unnatural-amino-acid-containing protein
WO2024077277A1 (en) 2022-10-07 2024-04-11 Ambrx, Inc. Drug linkers and antibody conjugates thereof
WO2024155627A1 (en) 2023-01-16 2024-07-25 Ambrx, Inc. Anti-cd70 antibody-drug conjugates
WO2024178310A1 (en) 2023-02-23 2024-08-29 Ambrx, Inc. Trop2-directed antibody-drug conjugates and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107329A (en) * 1995-06-06 2000-08-22 Pfizer, Inc. Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors
AU3485999A (en) * 1998-04-10 1999-11-01 Mayo Foundation For Medical Education And Research Neo-tryptophan
US6858577B1 (en) * 1999-06-29 2005-02-22 Ortho-Mcneil Pharmaceutical, Inc. Indole peptidomimetics as thrombin receptor antagonists
EP1291341A4 (en) * 2000-05-30 2005-04-27 Chugai Pharmaceutical Co Ltd COMPOUNDS WITH THROMBOPOIETINIC EFFECT
JP4623962B2 (ja) * 2001-10-22 2011-02-02 ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティ・オブ・ニューヨーク タンパク質キナーゼおよびホスファターゼ阻害剤、それらを設計する方法、ならびにそれらを使用する方法

Also Published As

Publication number Publication date
JP2010512800A (ja) 2010-04-30
MX2009006617A (es) 2009-07-24
WO2011028195A3 (en) 2011-06-16
CN101578264A (zh) 2009-11-11
CA2672205A1 (en) 2008-06-26
EP2079687A1 (en) 2009-07-22
WO2008077079A1 (en) 2008-06-26
WO2011028195A2 (en) 2011-03-10
KR20090100407A (ko) 2009-09-23

Similar Documents

Publication Publication Date Title
EP1828224B1 (en) Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
AU2007333737A1 (en) Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
AU2006332809A1 (en) Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
AU2013205042B2 (en) Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
AU2012202615B2 (en) Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted