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AU2003226955A1 - Translocation dependent complementation for drug screening - Google Patents

Translocation dependent complementation for drug screening

Info

Publication number
AU2003226955A1
AU2003226955A1 AU2003226955A AU2003226955A AU2003226955A1 AU 2003226955 A1 AU2003226955 A1 AU 2003226955A1 AU 2003226955 A AU2003226955 A AU 2003226955A AU 2003226955 A AU2003226955 A AU 2003226955A AU 2003226955 A1 AU2003226955 A1 AU 2003226955A1
Authority
AU
Australia
Prior art keywords
drug screening
translocation
dependent complementation
complementation
translocation dependent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003226955A
Inventor
Soren Weis Dahl
Grith Hagel
Soren Jensby Nielsen
Morten Praestegaard
Bernard Robert Terry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioImage AS
Original Assignee
BioImage AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2002/000882 external-priority patent/WO2003089464A1/en
Application filed by BioImage AS filed Critical BioImage AS
Publication of AU2003226955A1 publication Critical patent/AU2003226955A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003226955A 2002-04-19 2003-04-22 Translocation dependent complementation for drug screening Abandoned AU2003226955A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DKPA200200591 2002-04-19
DKPA200200591 2002-04-19
DKPA200200896 2002-06-13
DKPA200200896 2002-06-13
DKPA200201029 2002-07-01
DKPA200201029 2002-07-01
AU2002358466 2002-12-19
PCT/DK2002/000882 WO2003089464A1 (en) 2002-04-19 2002-12-19 Two green fluorescent protein fragments and their use in a method for detecting protein - protein interactions
PCT/DK2003/000266 WO2003089627A1 (en) 2002-04-19 2003-04-22 Translocation dependent complementation for drug screening

Publications (1)

Publication Number Publication Date
AU2003226955A1 true AU2003226955A1 (en) 2003-11-03

Family

ID=29255411

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003226955A Abandoned AU2003226955A1 (en) 2002-04-19 2003-04-22 Translocation dependent complementation for drug screening

Country Status (4)

Country Link
EP (1) EP1509596A1 (en)
JP (1) JP2005527210A (en)
AU (1) AU2003226955A1 (en)
WO (1) WO2003089627A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7166424B2 (en) * 1998-02-02 2007-01-23 Odyssey Thera Inc. Fragments of fluorescent proteins for protein fragment complementation assays
WO2005074436A2 (en) * 2003-10-24 2005-08-18 The Regents Of The University Of California Self-assembling split-fluorescent protein systems
GB0327143D0 (en) * 2003-11-21 2003-12-24 Univ Belfast Assay
EP1766095B1 (en) * 2004-05-18 2013-10-23 The Board of Trustees of the Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
DE05739600T1 (en) * 2004-05-19 2006-12-28 Kobenhavns Universitet ADAM12, A NEW MARKER FOR ABNORMAL CELL FUNCTION
US20060040338A1 (en) * 2004-08-18 2006-02-23 Odyssey Thera, Inc. Pharmacological profiling of drugs with cell-based assays
EP1674478A1 (en) * 2004-12-22 2006-06-28 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Fusion proteins and method for determining protein-protein-interactions in living cells and cell lysates, nucleic acids encoding these fusion proteins, as well as vectors and kits containing these
EP1899479A4 (en) * 2005-06-21 2010-01-20 Discoverx Corp Mitotic index assay
GB201503133D0 (en) 2015-02-24 2015-04-08 Ucl Business Plc And Syncona Partners Llp Chimeric protein
CN112279921A (en) * 2019-07-11 2021-01-29 厦门大学 Complexes for intracellular delivery of molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4906100A (en) * 1999-05-27 2000-12-18 Merck Frosst Canada & Co. Assays for caspase activity using green fluorescent proteins
US6780599B2 (en) * 2000-05-12 2004-08-24 Yale University Methods of detecting interactions between proteins, peptides or libraries thereof using fusion proteins

Also Published As

Publication number Publication date
WO2003089627A1 (en) 2003-10-30
JP2005527210A (en) 2005-09-15
EP1509596A1 (en) 2005-03-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase