ATE90076T1 - Tetrahydrocarbazole ester. - Google Patents
Tetrahydrocarbazole ester.Info
- Publication number
- ATE90076T1 ATE90076T1 AT87302290T AT87302290T ATE90076T1 AT E90076 T1 ATE90076 T1 AT E90076T1 AT 87302290 T AT87302290 T AT 87302290T AT 87302290 T AT87302290 T AT 87302290T AT E90076 T1 ATE90076 T1 AT E90076T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydrocarbazole
- ester
- dysmenorrhea
- prostaglandin
- angina
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA505362 | 1986-03-27 | ||
| EP87302290A EP0239306B1 (de) | 1986-03-27 | 1987-03-18 | Tetrahydrocarbazole Ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE90076T1 true ATE90076T1 (de) | 1993-06-15 |
Family
ID=4132762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87302290T ATE90076T1 (de) | 1986-03-27 | 1987-03-18 | Tetrahydrocarbazole ester. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0239306B1 (de) |
| JP (1) | JPS6317861A (de) |
| AT (1) | ATE90076T1 (de) |
| DE (1) | DE3786030T2 (de) |
| DK (1) | DK153987A (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4940719A (en) * | 1986-03-27 | 1990-07-10 | Merck Frosst Canada, Inc. | Tetrahydrocarbazole esters, pharmaceutical compositions and use |
| DE10164564B4 (de) | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
| AU2002361430B2 (en) * | 2001-12-14 | 2007-09-13 | Zentaris Gmbh | Tetrahydrocarbozole derivatives as ligands for G-protein coupled receptors (GPCR) |
| DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
| EP2095818A1 (de) | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1144905A (en) | 1965-03-25 | 1969-03-12 | Fisons Pharmaceuticals Ltd | Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof |
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3630200A (en) | 1969-06-09 | 1971-12-28 | Alza Corp | Ocular insert |
| US3687969A (en) | 1970-06-02 | 1972-08-29 | Sterling Drug Inc | 9-aroyl-1,2,3,4-tetrahydrocarbazole-3,3-dicarboxylic acids |
| US3868387A (en) | 1971-04-15 | 1975-02-25 | Hoffmann La Roche | 1,2,3,4-tetrahydrocarbazole-2-carboxylic acids and their derivatives |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3896145A (en) * | 1972-07-24 | 1975-07-22 | Hoffmann La Roche | Carbazoles |
| AR205331A1 (es) | 1972-07-24 | 1976-04-30 | Hoffmann La Roche | Procedimiento para la preparacion de carbazoles |
| US4009181A (en) | 1973-01-22 | 1977-02-22 | Hoffmann-La Roche Inc. | Cyclopenta[b]indole-2-carboxylic acids and derivatives thereof |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| DE2337154C2 (de) | 1973-07-18 | 1986-04-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue Carbazolderivate |
| US4057640A (en) | 1973-07-18 | 1977-11-08 | Schering Aktiengesellschaft | 5,6,7,8:Tetrahydrocarbazole-1-carboxylic acid derivatives |
| GB1511169A (en) * | 1975-08-29 | 1978-05-17 | American Home Prod | Trycyclic acetic acid derivatives |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4325961A (en) | 1977-06-01 | 1982-04-20 | Merck & Co., Inc. | Fluorinated amino acids |
| PT68303A (en) | 1977-07-26 | 1978-08-01 | Merck & Co Inc | Process for the preparation of dibenzo/b,f/thiepin |
| DE2960547D1 (en) | 1978-02-24 | 1981-11-05 | Pfizer Ltd | 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| JPS55313A (en) | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
| IL58849A (en) | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
| DK471479A (da) | 1978-12-13 | 1980-06-14 | Pfizer | Fremgangsmaade til fremstilling af imidazolderivater og salte deraf |
| JPS6056143B2 (ja) | 1979-08-02 | 1985-12-09 | 山之内製薬株式会社 | アミジン誘導体ならびにその製造法 |
| PH16099A (en) | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
| DK151884C (da) | 1979-03-07 | 1988-06-13 | Pfizer | Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf |
| GB2058785B (en) | 1979-09-05 | 1983-05-25 | Glaxo Group Ltd | Phenol derivatives |
| US4237160A (en) | 1979-11-27 | 1980-12-02 | Merck Sharp & Dohme (I.A.) Corp. | 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists |
| DE3175201D1 (en) | 1980-04-30 | 1986-10-02 | Merck & Co Inc | Aminothiadiazoles as gastric secretion inhibitors |
| US4394508A (en) | 1980-06-07 | 1983-07-19 | Bristol-Myers Company | Chemical compounds |
| DE3169761D1 (en) | 1981-01-09 | 1985-05-09 | Fisons Plc | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them |
| DE3265715D1 (en) | 1981-03-24 | 1985-10-03 | Fisons Plc | Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them |
| US4444775A (en) | 1981-06-22 | 1984-04-24 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridines |
| US4495357A (en) | 1981-07-01 | 1985-01-22 | The Upjohn Company | Pyridyl-substituted-benzofurans |
| DE3373467D1 (en) | 1982-06-14 | 1987-10-15 | Takeda Chemical Industries Ltd | Vinyl carboxylic acid derivatives, their production and use |
| IL69691A (en) | 1982-09-23 | 1988-01-31 | Merck Frosst Canada Inc | Leukotriene antagonists,their preparation and pharmaceutical compositions containing them |
| DE3366107D1 (en) | 1982-09-30 | 1986-10-16 | Merck Frosst Canada Inc | Leukotriene antagonists, their production, and compositions containing them |
| NZ206795A (en) | 1983-01-21 | 1987-08-31 | Merck Frosst Canada Inc | Phenothiazines, analogues and pharmaceutical compositions |
| EP0138481B1 (de) | 1983-10-05 | 1991-06-26 | Merck Frosst Canada Inc. | Inhibitoren für die Leukotrien-Biosynthese |
| DE3479397D1 (en) | 1983-10-05 | 1989-09-21 | Merck Frosst Canada Inc | Benzoûa¨phenothiazines and hydro-derivatives and pharmaceutical compositions containing them |
| ES8602818A1 (es) | 1983-10-31 | 1985-12-01 | Merck Frosst Canada Inc | Una composicion farmaceutica |
| US4558037A (en) | 1984-06-04 | 1985-12-10 | Merck & Co., Inc. | Cardiovascular composition |
| US4616028A (en) * | 1985-04-22 | 1986-10-07 | American Home Products Corporation | Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, compositions and use |
| DE3768097D1 (de) * | 1986-01-23 | 1991-04-04 | Merck Frosst Canada Inc | Tetrahydrocarbazol-1-alkansaeuren. |
-
1987
- 1987-03-18 AT AT87302290T patent/ATE90076T1/de active
- 1987-03-18 DE DE87302290T patent/DE3786030T2/de not_active Expired - Fee Related
- 1987-03-18 EP EP87302290A patent/EP0239306B1/de not_active Expired - Lifetime
- 1987-03-26 DK DK153987A patent/DK153987A/da not_active IP Right Cessation
- 1987-03-27 JP JP62071951A patent/JPS6317861A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE3786030T2 (de) | 1993-12-02 |
| JPS6317861A (ja) | 1988-01-25 |
| EP0239306A3 (en) | 1989-02-08 |
| DK153987A (da) | 1987-09-28 |
| DE3786030D1 (de) | 1993-07-08 |
| EP0239306B1 (de) | 1993-06-02 |
| EP0239306A2 (de) | 1987-09-30 |
| DK153987D0 (da) | 1987-03-26 |
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