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ATE53995T1 - Tricyclisches derivat, naemlich 5-(3-chloro-6methyl-5,5-dioxo-6,11-dihydro-dibenzo(c,f> (1,2>- thiazepin-11-yl amino)-pentansaeure, verfahren zu seiner herstellung und dieses enthaltende arzneimittel. - Google Patents

Tricyclisches derivat, naemlich 5-(3-chloro-6methyl-5,5-dioxo-6,11-dihydro-dibenzo(c,f> (1,2>- thiazepin-11-yl amino)-pentansaeure, verfahren zu seiner herstellung und dieses enthaltende arzneimittel.

Info

Publication number
ATE53995T1
ATE53995T1 AT87400371T AT87400371T ATE53995T1 AT E53995 T1 ATE53995 T1 AT E53995T1 AT 87400371 T AT87400371 T AT 87400371T AT 87400371 T AT87400371 T AT 87400371T AT E53995 T1 ATE53995 T1 AT E53995T1
Authority
AT
Austria
Prior art keywords
thiazepin
dibenzo
dioxo
dihydro
chloro
Prior art date
Application number
AT87400371T
Other languages
English (en)
Inventor
Charles Malen
Jean-Claude Poignant
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE53995T1 publication Critical patent/ATE53995T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT87400371T 1986-02-21 1987-02-20 Tricyclisches derivat, naemlich 5-(3-chloro-6methyl-5,5-dioxo-6,11-dihydro-dibenzo(c,f> (1,2>- thiazepin-11-yl amino)-pentansaeure, verfahren zu seiner herstellung und dieses enthaltende arzneimittel. ATE53995T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8602399A FR2594827B1 (fr) 1986-02-21 1986-02-21 Nouveau derive tricyclique denomme acide ((chloro-3 methyl-6 dioxo-5,5 dihydro-6, 11 dibenzo (c,f) thiazepine (1,2) yl-11 amino)-5 pentazoique, son procede de preparation et les compositions pharmaceutiques qui le contiennent
EP87400371A EP0239436B1 (de) 1986-02-21 1987-02-20 Tricyclisches Derivat, nämlich 5-(3-Chloro-6-methyl-5,5-dioxo-6,11-dihydro-dibenzo[c,f] [1,2]-thiazepin-11-yl amino)-pentansäure, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE53995T1 true ATE53995T1 (de) 1990-07-15

Family

ID=9332386

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87400371T ATE53995T1 (de) 1986-02-21 1987-02-20 Tricyclisches derivat, naemlich 5-(3-chloro-6methyl-5,5-dioxo-6,11-dihydro-dibenzo(c,f> (1,2>- thiazepin-11-yl amino)-pentansaeure, verfahren zu seiner herstellung und dieses enthaltende arzneimittel.

Country Status (12)

Country Link
US (1) US4766114A (de)
EP (1) EP0239436B1 (de)
JP (1) JPS62198672A (de)
AT (1) ATE53995T1 (de)
CA (1) CA1282781C (de)
DE (1) DE3763311D1 (de)
DK (1) DK88087A (de)
ES (1) ES2004097A6 (de)
FR (1) FR2594827B1 (de)
GR (1) GR870285B (de)
IE (1) IE59468B1 (de)
PT (1) PT84332B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040629B1 (es) * 1991-12-18 1994-06-16 Consejo Superior Investigacion Procedimiento de obtencion de derivados triciclicos de la benzotiazepina farmacologicamente activos.
US5716949A (en) * 1995-04-07 1998-02-10 Novo Nordisk A/S Heterocyclic compounds
US6683072B1 (en) 2003-02-04 2004-01-27 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia
US20050227961A1 (en) * 2004-04-08 2005-10-13 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome
TWI436988B (zh) * 2007-03-05 2014-05-11 Transform Pharmaceuticals Inc ７-〔（３-氯-６，１１-二氫-６-甲基二苯并〔ｃ，ｆ〕〔１，２〕噻氮呯-１１-基）胺〕庚酸ｓ，ｓ二氧化物之多晶型及其製造與使用方法
US9314469B2 (en) 2008-05-05 2016-04-19 Tonix Pharma Holdings Limited Method for treating neurocognitive dysfunction
GB201208315D0 (en) 2012-05-11 2012-06-27 Numedicus Ltd Pharmaceutical methods and compositions
JP6557674B2 (ja) * 2014-03-12 2019-08-07 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 新規クラスのミュー−オピオイド受容体アゴニスト
WO2017049158A1 (en) 2015-09-16 2017-03-23 The Trustees Of Columbia University In The City Of New York Carboxylic diarylthiazepineamines as mu-opioid receptor agonists
WO2022074587A1 (en) * 2020-10-06 2022-04-14 Kures, Inc. Mu-opioid receptor agonists and uses therefor
US20230365519A1 (en) * 2020-10-06 2023-11-16 Kures, Inc. Carboxylic diarylthiazepineamines and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1269551A (en) * 1969-03-27 1972-04-06 Science Union & Cie New tricyclic derivatives and process for their manufacture
US3821249A (en) * 1970-03-13 1974-06-28 En Nom Collectif Science Union Dibenzothiazefin derivatives

Also Published As

Publication number Publication date
US4766114A (en) 1988-08-23
EP0239436A1 (de) 1987-09-30
EP0239436B1 (de) 1990-06-20
PT84332B (pt) 1989-09-14
ES2004097A6 (es) 1988-12-01
FR2594827A1 (fr) 1987-08-28
CA1282781C (fr) 1991-04-09
IE870427L (en) 1987-08-21
GR870285B (en) 1987-06-30
DE3763311D1 (de) 1990-07-26
IE59468B1 (en) 1994-03-09
DK88087D0 (da) 1987-02-20
JPS62198672A (ja) 1987-09-02
FR2594827B1 (fr) 1988-05-20
JPH0378858B2 (de) 1991-12-17
DK88087A (da) 1987-08-22
PT84332A (fr) 1987-03-01

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