ATE53944T1 - Waessrige fluessige zubereitungen. - Google Patents
Waessrige fluessige zubereitungen.Info
- Publication number
- ATE53944T1 ATE53944T1 AT86111306T AT86111306T ATE53944T1 AT E53944 T1 ATE53944 T1 AT E53944T1 AT 86111306 T AT86111306 T AT 86111306T AT 86111306 T AT86111306 T AT 86111306T AT E53944 T1 ATE53944 T1 AT E53944T1
- Authority
- AT
- Austria
- Prior art keywords
- aqueous liquid
- liquid preparations
- irritation
- compound
- heightened
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18238385 | 1985-08-19 | ||
EP86111306A EP0213514B1 (de) | 1985-08-19 | 1986-08-15 | Wässrige flüssige Zubereitungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE53944T1 true ATE53944T1 (de) | 1990-07-15 |
Family
ID=16117350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86111306T ATE53944T1 (de) | 1985-08-19 | 1986-08-15 | Waessrige fluessige zubereitungen. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4728509A (de) |
EP (1) | EP0213514B1 (de) |
JP (1) | JPS62123116A (de) |
AT (1) | ATE53944T1 (de) |
CA (1) | CA1269618A (de) |
DE (1) | DE3672097D1 (de) |
DK (1) | DK166757B1 (de) |
IE (1) | IE59425B1 (de) |
MY (1) | MY102075A (de) |
NO (1) | NO171005C (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8629639D0 (en) * | 1986-12-11 | 1987-01-21 | Beecham Group Plc | Composition & method |
US4940701A (en) * | 1984-01-25 | 1990-07-10 | Beecham Group P.L.C. | Topical drug release system |
GB8629640D0 (en) * | 1986-12-11 | 1987-01-21 | Beecham Group Plc | Composition & method |
US4778810A (en) * | 1987-01-08 | 1988-10-18 | Nastech Pharmaceutical Co., Inc. | Nasal delivery of caffeine |
US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
US5017566A (en) * | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
ES2012532A6 (es) * | 1988-07-15 | 1990-04-01 | Cusi Lab | Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica. |
US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
JPH0714872B2 (ja) * | 1990-02-06 | 1995-02-22 | 昭和薬品化工株式会社 | シロップ剤組成物 |
US20040014695A1 (en) * | 1992-06-19 | 2004-01-22 | Supergen, Inc. | Pharmaceutical formulation |
US5602112A (en) | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
US5472954A (en) * | 1992-07-14 | 1995-12-05 | Cyclops H.F. | Cyclodextrin complexation |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
US5494901A (en) * | 1993-01-05 | 1996-02-27 | Javitt; Jonathan C. | Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent |
EP0621036B1 (de) * | 1993-04-22 | 1999-03-17 | Senju Pharmaceutical Co., Ltd. | Wässrige Arzneizubereitungen enthaltend Argatroban und Cyclodextrin oder Coffein |
US5519030A (en) * | 1993-10-07 | 1996-05-21 | Senju Pharmaceutical Co., Ltd. | Method for prophylaxis and treatment of myopia |
US5897858A (en) | 1994-02-03 | 1999-04-27 | Schering-Plough Healthcare Products, Inc. | Nasal spray compositions exhibiting increased retention in the nasal cavity |
US5824668A (en) * | 1996-11-07 | 1998-10-20 | Supergen, Inc. | Formulation for administration of steroid compounds |
US5952338A (en) * | 1996-07-05 | 1999-09-14 | Takeda Chemical Industries, Ltd. | Agent for prophylaxis and treatment of disturbance of visual function |
JP4439596B2 (ja) * | 1997-06-13 | 2010-03-24 | サイデクス ファーマシューティカルズ、 インク. | 長期の貯蔵寿命を有する、極性薬物又は極性プロドラッグを含有する医薬組成物、及びその製造方法 |
US20040152664A1 (en) * | 1998-09-02 | 2004-08-05 | Allergan, Inc. | Prednisolone compositions |
CA2342797A1 (en) | 1998-09-02 | 2000-03-09 | Allergan Sales, Inc. | Preserved cyclodextrin-containing compositions |
JP2001125052A (ja) * | 1999-10-25 | 2001-05-11 | Lion Corp | コンタクトレンズ装着液 |
EP1312380B1 (de) * | 2000-06-19 | 2006-05-03 | Santen Pharmaceutical Co., Ltd. | Aseptische mittel |
PE20060484A1 (es) * | 2004-07-14 | 2006-07-06 | Ucb Farchim Sa | Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina |
TR201820559T4 (tr) | 2004-11-24 | 2019-01-21 | Meda Pharmaceuticals Inc | Azelastin içeren kompozisyonlar ve bunların kullanım metotları. |
US20070020330A1 (en) * | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
US8758816B2 (en) * | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
WO2006099359A2 (en) | 2005-03-10 | 2006-09-21 | 3M Innovative Properties Company | Methods of reducing microbial contamination |
US20070010487A1 (en) * | 2005-07-06 | 2007-01-11 | Jeff Schwegman | Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins |
US20070009531A1 (en) * | 2005-07-06 | 2007-01-11 | Branimir Sikic | Treatment of patients with cancer using a calicheamicin-antibody conjugate in combination with zosuquidar |
US20070010485A1 (en) * | 2005-07-06 | 2007-01-11 | Jeff Schwegman | Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins |
US20070010466A1 (en) * | 2005-07-06 | 2007-01-11 | Branimir Sikic | Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer |
SI2493474T1 (sl) * | 2009-10-30 | 2019-11-29 | Intratus Inc | Postopki in sestavki za trajno dovajanje zdravil |
CN103140215A (zh) * | 2010-07-21 | 2013-06-05 | 爱尔康研究有限公司 | 具有提高的溶解度特征的药物组合物 |
US10245255B2 (en) | 2011-02-14 | 2019-04-02 | The Regents Of The University Of Michigan | Compositions and methods for the treatment of obesity and related disorders |
CN103998046B (zh) | 2011-11-29 | 2021-04-06 | 优奥斯私人有限公司 | 包含环糊精和疏水性药物的可注射药物组合物的防腐方法 |
US9365581B2 (en) | 2013-05-02 | 2016-06-14 | The Regents Of The University Of Michigan | Deuterated amlexanox |
EP3407974A4 (de) | 2016-01-29 | 2019-08-28 | The Regents Of The University Of Michigan | Amlexanox-analoga |
EP3505154B1 (de) * | 2017-12-26 | 2022-04-06 | Industrial Technology Research Institute | Zusammensetzung zur verbesserung der löslichkeit schwerlöslicher substanzen, ihre verwendung und diese enthaltende komplexe formulierung |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD7498A1 (de) * | 1951-02-20 | 1954-05-31 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung von haltbaren Lösungen in 1,3-Stellung substituierter Xanthine |
JPS5831210B2 (ja) * | 1973-04-09 | 1983-07-05 | 武田薬品工業株式会社 | アンテイナスイセイケンダクエキノセイゾウホウ |
JPS53111096A (en) * | 1977-03-08 | 1978-09-28 | Takeda Chem Ind Ltd | 1-azaxanthone-3-carboxylic acid derivative and its preparation |
US4143042A (en) * | 1977-03-08 | 1979-03-06 | Takeda Chemical Industries, Ltd. | 1-azaxanthone-3-carboxylic acids |
JPS54115398A (en) * | 1978-02-27 | 1979-09-07 | Takeda Chem Ind Ltd | 1-azaxanthone-3-carboxylic acid derivative and its preparation |
JPS6042766B2 (ja) * | 1978-12-09 | 1985-09-25 | 日本化薬株式会社 | 基剤 |
ZA815175B (en) * | 1980-08-01 | 1982-09-29 | Smith & Nephew Ass | Pharmaceutical composition |
JPS57200361A (en) * | 1981-06-03 | 1982-12-08 | Sumitomo Chem Co Ltd | "indomethacin(r)" pharmaceutical with low irritant action |
JPS58126810A (ja) * | 1981-12-24 | 1983-07-28 | Kaken Pharmaceut Co Ltd | 抗炎症眼科用液剤およびその製法 |
JPS58174310A (ja) * | 1982-04-06 | 1983-10-13 | Wakamoto Pharmaceut Co Ltd | 抗炎症点眼剤 |
DE3372705D1 (en) * | 1982-04-30 | 1987-09-03 | Takeda Chemical Industries Ltd | Pharmaceutical composition and its use |
US4539326A (en) * | 1982-08-20 | 1985-09-03 | Takeda Chemical Industries, Ltd. | 5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use as anti-inflammatory agents |
US4559343A (en) * | 1982-09-07 | 1985-12-17 | Alcon Laboratories, Inc. | Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents |
JPS59106424A (ja) * | 1982-12-09 | 1984-06-20 | Kyorin Pharmaceut Co Ltd | 易吸収性キノリンカルボン酸誘導体組成物およびその製剤 |
JPS59152320A (ja) * | 1983-02-17 | 1984-08-31 | Takeda Chem Ind Ltd | 水性製剤 |
KR920010047B1 (ko) * | 1985-01-28 | 1992-11-13 | 다께다야꾸힝고오교 가부시끼가이샤 | 2-아미노-5-옥소-5H-[1]벤조피라노[2,3-b]피리딘-3-카르복실산 유도체의 제조방법 |
-
1986
- 1986-08-05 US US06/893,161 patent/US4728509A/en not_active Expired - Lifetime
- 1986-08-08 DK DK379986A patent/DK166757B1/da not_active IP Right Cessation
- 1986-08-12 NO NO863253A patent/NO171005C/no unknown
- 1986-08-15 EP EP86111306A patent/EP0213514B1/de not_active Expired - Lifetime
- 1986-08-15 AT AT86111306T patent/ATE53944T1/de not_active IP Right Cessation
- 1986-08-15 DE DE8686111306T patent/DE3672097D1/de not_active Expired - Fee Related
- 1986-08-18 JP JP61193834A patent/JPS62123116A/ja active Granted
- 1986-08-18 IE IE221486A patent/IE59425B1/en not_active IP Right Cessation
- 1986-08-18 CA CA000516160A patent/CA1269618A/en not_active Expired - Lifetime
-
1987
- 1987-09-29 MY MYPI87002198A patent/MY102075A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE3672097D1 (de) | 1990-07-26 |
NO863253D0 (no) | 1986-08-12 |
DK166757B1 (da) | 1993-07-12 |
EP0213514A2 (de) | 1987-03-11 |
JPH0478614B2 (de) | 1992-12-11 |
NO863253L (no) | 1987-02-20 |
IE59425B1 (en) | 1994-02-23 |
MY102075A (en) | 1992-03-31 |
NO171005B (no) | 1992-10-05 |
DK379986A (da) | 1987-02-20 |
US4728509A (en) | 1988-03-01 |
DK379986D0 (da) | 1986-08-08 |
JPS62123116A (ja) | 1987-06-04 |
EP0213514A3 (en) | 1987-07-22 |
CA1269618A (en) | 1990-05-29 |
NO171005C (no) | 1993-01-13 |
EP0213514B1 (de) | 1990-06-20 |
IE862214L (en) | 1987-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |