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KR880001651A - 이미다조 [4,5-b] 피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제 - Google Patents

이미다조 [4,5-b] 피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제 Download PDF

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Publication number
KR880001651A
KR880001651A KR1019870008092A KR870008092A KR880001651A KR 880001651 A KR880001651 A KR 880001651A KR 1019870008092 A KR1019870008092 A KR 1019870008092A KR 870008092 A KR870008092 A KR 870008092A KR 880001651 A KR880001651 A KR 880001651A
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South Korea
Prior art keywords
group
imidazo
carbon atoms
hydrogen atom
same
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KR1019870008092A
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English (en)
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KR940002824B1 (ko
Inventor
나오또 마쓰이시
하루끼 다께다
겐이찌 이이즈미
기요까즈 무라까미
아끼라 히사미쯔
Original Assignee
노베고지
도오꾜 다나베세이야꾸 가부시끼 가이샤
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Publication of KR880001651A publication Critical patent/KR880001651A/ko
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Publication of KR940002824B1 publication Critical patent/KR940002824B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

이미다조 〔4,5-b〕피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체.
    (상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)
  2. 하기 일반식(Ⅱ)으로 표시되는 술피드 화합물을 산화시켜 얻어지는 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체의 제조방법.
    (상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)
  3. 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체를 유효성분으로 하는 항궤양제.
    (상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870008092A 1986-07-25 1987-07-24 이미다조[4,5-b]피리딘 유도체 및 그의 제조방법 KR940002824B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP173551 1986-07-25
JP17355186 1986-07-25
JP173551/86 1986-07-25
JP133534 1987-05-30
JP62133534A JPH0643426B2 (ja) 1986-07-25 1987-05-30 イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
JP133534/87 1987-05-30

Publications (2)

Publication Number Publication Date
KR880001651A true KR880001651A (ko) 1988-04-25
KR940002824B1 KR940002824B1 (ko) 1994-04-04

Family

ID=26467860

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870008092A KR940002824B1 (ko) 1986-07-25 1987-07-24 이미다조[4,5-b]피리딘 유도체 및 그의 제조방법

Country Status (14)

Country Link
US (1) US4808596A (ko)
EP (1) EP0254588B1 (ko)
JP (1) JPH0643426B2 (ko)
KR (1) KR940002824B1 (ko)
AR (1) AR245718A1 (ko)
AT (1) ATE71626T1 (ko)
AU (1) AU598564B2 (ko)
CA (1) CA1329204C (ko)
DE (1) DE3776018D1 (ko)
ES (1) ES2038184T3 (ko)
GR (1) GR3003777T3 (ko)
HU (1) HU200458B (ko)
MX (1) MX168756B (ko)
ZA (1) ZA875151B (ko)

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Also Published As

Publication number Publication date
ES2038184T3 (es) 1993-07-16
JPS63146882A (ja) 1988-06-18
KR940002824B1 (ko) 1994-04-04
AR245718A1 (es) 1994-02-28
DE3776018D1 (de) 1992-02-27
ZA875151B (en) 1988-01-21
HU200458B (en) 1990-06-28
CA1329204C (en) 1994-05-03
ATE71626T1 (de) 1992-02-15
US4808596A (en) 1989-02-28
EP0254588B1 (en) 1992-01-15
AU7562887A (en) 1988-01-28
JPH0643426B2 (ja) 1994-06-08
EP0254588A1 (en) 1988-01-27
HUT46000A (en) 1988-09-28
MX168756B (es) 1993-06-07
GR3003777T3 (ko) 1993-03-16
AU598564B2 (en) 1990-06-28

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