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ATE53025T1 - 7-(2-(dialkylamino)ethly>-4-hydroxy-1,3benzimidazol-2-one. - Google Patents

7-(2-(dialkylamino)ethly>-4-hydroxy-1,3benzimidazol-2-one.

Info

Publication number
ATE53025T1
ATE53025T1 AT85306335T AT85306335T ATE53025T1 AT E53025 T1 ATE53025 T1 AT E53025T1 AT 85306335 T AT85306335 T AT 85306335T AT 85306335 T AT85306335 T AT 85306335T AT E53025 T1 ATE53025 T1 AT E53025T1
Authority
AT
Austria
Prior art keywords
ethly
dialkylamino
hydroxy
compounds
methoxyphenethyl
Prior art date
Application number
AT85306335T
Other languages
English (en)
Inventor
Orum David Stringer
Joseph Weinstock
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE53025T1 publication Critical patent/ATE53025T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT85306335T 1984-09-12 1985-09-06 7-(2-(dialkylamino)ethly>-4-hydroxy-1,3benzimidazol-2-one. ATE53025T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/649,465 US4554287A (en) 1984-09-12 1984-09-12 Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones
EP85306335A EP0175525B1 (de) 1984-09-12 1985-09-06 7-[2-(Dialkylamino)ethly]-4-hydroxy-1,3-benzimidazol-2-one

Publications (1)

Publication Number Publication Date
ATE53025T1 true ATE53025T1 (de) 1990-06-15

Family

ID=24604906

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85306335T ATE53025T1 (de) 1984-09-12 1985-09-06 7-(2-(dialkylamino)ethly>-4-hydroxy-1,3benzimidazol-2-one.

Country Status (12)

Country Link
US (1) US4554287A (de)
EP (1) EP0175525B1 (de)
JP (1) JPS6168473A (de)
AT (1) ATE53025T1 (de)
AU (1) AU586187B2 (de)
CA (1) CA1255685A (de)
DE (1) DE3577849D1 (de)
DK (1) DK407885A (de)
ES (1) ES8605491A1 (de)
GR (1) GR852189B (de)
PT (1) PT81109B (de)
ZA (1) ZA856943B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0189473B1 (de) * 1984-08-15 1992-05-27 Schering Aktiengesellschaft Neue dopamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3728695A1 (de) * 1987-08-25 1989-03-09 Schering Ag Neue benzimidazol-derivate
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
EP2303873A4 (de) 2008-06-18 2012-01-04 Astrazeneca Ab Benzoxazinonderivate als beta2-adrenorezeptoragonist zur behandlung von atemwegserkrankungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070478A (en) * 1977-02-17 1978-01-24 Merck & Co., Inc. Benzimidazole substituted alanines
US4179505A (en) * 1977-03-30 1979-12-18 Janssen Pharmaceutica N.V. 5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives
CA1108619A (en) * 1977-08-12 1981-09-08 Carl H. Ross 4-hydroxy-2-benzimidazolinone derivatives and the preparation thereof
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones

Also Published As

Publication number Publication date
DK407885A (da) 1986-03-13
GR852189B (de) 1986-01-10
US4554287A (en) 1985-11-19
ZA856943B (en) 1986-06-25
EP0175525A1 (de) 1986-03-26
AU4714485A (en) 1986-03-20
AU586187B2 (en) 1989-07-06
DK407885D0 (da) 1985-09-06
JPS6168473A (ja) 1986-04-08
ES546884A0 (es) 1986-03-16
EP0175525B1 (de) 1990-05-23
PT81109A (en) 1985-10-01
CA1255685A (en) 1989-06-13
ES8605491A1 (es) 1986-03-16
DE3577849D1 (de) 1990-06-28
PT81109B (en) 1987-07-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee