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ATE431361T1 - Verwendung vom transportergen oatp-c zur screening von testsubstanzen - Google Patents

Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Info

Publication number
ATE431361T1
ATE431361T1 AT04077191T AT04077191T ATE431361T1 AT E431361 T1 ATE431361 T1 AT E431361T1 AT 04077191 T AT04077191 T AT 04077191T AT 04077191 T AT04077191 T AT 04077191T AT E431361 T1 ATE431361 T1 AT E431361T1
Authority
AT
Austria
Prior art keywords
oatp
transporter genes
test substances
screening test
transporter
Prior art date
Application number
AT04077191T
Other languages
English (en)
Inventor
Jun-Ichi Nezu
Asuka Ose
Akira Tsuji
Original Assignee
Chugai Pharmaceutical Co Ltd
Akira Tsuji
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Akira Tsuji filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE431361T1 publication Critical patent/ATE431361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04077191T 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen ATE431361T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26783599 1999-09-21

Publications (1)

Publication Number Publication Date
ATE431361T1 true ATE431361T1 (de) 2009-05-15

Family

ID=17450292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04077191T ATE431361T1 (de) 1999-09-21 2000-09-20 Verwendung vom transportergen oatp-c zur screening von testsubstanzen

Country Status (7)

Country Link
US (3) US7045316B2 (de)
EP (4) EP1223217A4 (de)
JP (2) JP4838961B2 (de)
AT (1) ATE431361T1 (de)
AU (1) AU7317400A (de)
DE (1) DE60042220D1 (de)
WO (1) WO2001021792A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60042220D1 (de) 1999-09-21 2009-06-25 Chugai Pharmaceutical Co Ltd Verwendung vom transportergen oatp-c zur screening von testsubstanzen
AU2002256786A1 (en) * 2001-05-18 2002-12-03 Astrazeneca Ab Methods
US20040171010A1 (en) * 2001-05-24 2004-09-02 Rachael Moore Methods
US20080319795A1 (en) * 2002-11-21 2008-12-25 Cdex, Inc. System and methods for detection and identification of chemical substances
US7723019B2 (en) * 2003-05-20 2010-05-25 University Of Kentucky Research Foundation Organic cation transporter preferentially expressed in hematopoietic cells and leukemias and uses thereof
WO2004113558A1 (ja) * 2003-06-20 2004-12-29 Genomembrane, Inc. 乳癌治療剤のスクリーニング方法
US8110350B2 (en) 2005-11-17 2012-02-07 Karolinska Institutet Innovations Ab Human Bocavirus and methods of diagnosis and treatment
US7435771B2 (en) 2005-11-23 2008-10-14 Arch Chemicals, Inc. Stable antifouling paint composition containing metal salt of pyrithione and cuprous oxide
EP2684963B1 (de) * 2011-03-10 2016-02-03 Eisai R&D Management Co., Ltd. Verfahren zum screening einer verbindung zur verstärkung oder hemmung einer oatp1b1-transportaktivität und verfahren zur bestimmung des expressionslevels von oatp1b1
KR102429794B1 (ko) 2012-09-11 2022-08-08 디스커버리 라이프 사이언시즈, 엘엘씨 약물 트랜스포터 단백질(들) 및/또는 약물대사 효소(들)를 인코딩하는 유전자(들)를 일시적으로 과발현하는 소모성 냉동보존 세포

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WO1993002227A1 (en) 1991-07-15 1993-02-04 Eco-Tec Limited Process and apparatus for treating fluoride containing acid solutions
EP0746609A4 (de) 1991-12-17 1997-12-17 Genpharm Int Heterologe antikörper produzierende transgene nicht-humane tiere
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AU6819494A (en) 1993-04-26 1994-11-21 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
AU2271995A (en) * 1995-03-01 1996-09-18 Human Genome Sciences, Inc. Human amine transporter
JP4312259B2 (ja) 1995-04-27 2009-08-12 アムジェン フレモント インク． 免疫したゼノマウス（ＸｅｎｏＭｏｕｓｅ）に由来するヒト抗体
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US20020090622A1 (en) * 2000-08-23 2002-07-11 Monisola Adeokun Chemical compounds
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Also Published As

Publication number Publication date
DE60042220D1 (de) 2009-06-25
US20060121523A1 (en) 2006-06-08
US20100196960A1 (en) 2010-08-05
US20030022199A1 (en) 2003-01-30
JP4838961B2 (ja) 2011-12-14
EP1486510A1 (de) 2004-12-15
US7045316B2 (en) 2006-05-16
EP1223217A1 (de) 2002-07-17
WO2001021792A1 (fr) 2001-03-29
AU7317400A (en) 2001-04-24
EP2030985A1 (de) 2009-03-04
EP1223217A4 (de) 2003-06-25
JP2011015694A (ja) 2011-01-27
JP5395767B2 (ja) 2014-01-22
EP1486510B1 (de) 2009-05-13
US8748128B2 (en) 2014-06-10
EP2316848A1 (de) 2011-05-04

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