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ATE427743T1 - Auf aussere bedingungen ansprechende polymere hohle partikel - Google Patents

Auf aussere bedingungen ansprechende polymere hohle partikel

Info

Publication number
ATE427743T1
ATE427743T1 AT00992341T AT00992341T ATE427743T1 AT E427743 T1 ATE427743 T1 AT E427743T1 AT 00992341 T AT00992341 T AT 00992341T AT 00992341 T AT00992341 T AT 00992341T AT E427743 T1 ATE427743 T1 AT E427743T1
Authority
AT
Austria
Prior art keywords
particles
stimulus
permeability
polymeric hollow
agent
Prior art date
Application number
AT00992341T
Other languages
English (en)
Inventor
Wolfgang Meier
Marc Sauer
Original Assignee
Biocure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocure Inc filed Critical Biocure Inc
Application granted granted Critical
Publication of ATE427743T1 publication Critical patent/ATE427743T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813—Carrier is a saccharide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/817—Entrapped within the carrier, e.g. gel, hollow fibre

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
AT00992341T 1999-11-15 2000-11-15 Auf aussere bedingungen ansprechende polymere hohle partikel ATE427743T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16549499P 1999-11-15 1999-11-15

Publications (1)

Publication Number Publication Date
ATE427743T1 true ATE427743T1 (de) 2009-04-15

Family

ID=22599135

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00992341T ATE427743T1 (de) 1999-11-15 2000-11-15 Auf aussere bedingungen ansprechende polymere hohle partikel

Country Status (8)

Country Link
US (1) US6616946B1 (de)
EP (1) EP1231905B1 (de)
JP (1) JP2003514650A (de)
AT (1) ATE427743T1 (de)
AU (1) AU4304901A (de)
CA (1) CA2391660C (de)
DE (1) DE60041978D1 (de)
WO (1) WO2001037803A2 (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10042023C2 (de) * 2000-08-08 2003-04-10 Biognostic Ag Kapseln, die feste Teilchen signalerzeugender Substanzen einkapseln, und deren Verwendung bei Bioassays zum Nachweis von Zielmolekülen in einer Probe
US20040013721A1 (en) * 2000-08-28 2004-01-22 Alexei Antipov Controlled and sustained release properties of polyelectrolyte multilayer capsules
US7311722B2 (en) * 2001-01-22 2007-12-25 Eric Larsen Photodynamic stimulation device and methods
JP2003089752A (ja) * 2001-03-23 2003-03-28 Canon Inc 刺激応答性ポリマーを含む組成物、それを含むインク組成物、並びに該インク組成物を用いた画像形成方法および装置
JP3595805B2 (ja) 2001-08-07 2004-12-02 キヤノン株式会社 刺激応答性組成物、並びに該組成物を用いた画像形成方法および装置
US7053034B2 (en) * 2002-04-10 2006-05-30 Salvona, Llc Targeted controlled delivery compositions activated by changes in pH or salt concentration
JP2004176036A (ja) * 2002-04-26 2004-06-24 Canon Inc 重合性化合物、高分子化合物、それらを用いた組成物及び記録方法並びに記録装置
US20040043070A1 (en) * 2002-05-14 2004-03-04 Ayres James W. Hot melt coating by direct blending and coated substrates
US20060182752A1 (en) * 2003-05-15 2006-08-17 Rutgers, The State University Tri-block polymers for nanosphere-based drug or gene delivery
US20040019008A1 (en) * 2002-05-28 2004-01-29 Lewis David L. Compositions and processes using siRNA, amphipathic compounds and polycations
WO2003104307A1 (en) * 2002-06-10 2003-12-18 Rhodia Inc Phase-separated composition comprising two miscible solvents, and use thereof in a process for making capsules
JP3890266B2 (ja) * 2002-07-03 2007-03-07 キヤノン株式会社 ブロックポリマー化合物、インク組成物、分散性組成物及び画像形成方法並びに画像形成装置
US7407768B2 (en) * 2002-09-11 2008-08-05 Synamem Corporation Membrane-based assays
US7153494B2 (en) * 2002-10-21 2006-12-26 L'oreal Dibenzoylmethane sunscreen compositions photostabilized with amphiphilic block copolymers
US20040151691A1 (en) * 2003-01-30 2004-08-05 Oxman Joel D. Hardenable thermally responsive compositions
US20040185013A1 (en) * 2003-01-30 2004-09-23 Burgio Paul A. Dental whitening compositions and methods
US7223826B2 (en) * 2003-01-30 2007-05-29 3M Innovative Properties Company Amide-functional polymers, compositions, and methods
US7682626B2 (en) * 2003-02-07 2010-03-23 Roche Madison Inc. Polyvinylethers for delivery of polynucleotides to mammalian cells
US8071078B2 (en) 2003-02-26 2011-12-06 Basf Se Encapsulated colorants for natural skin appearance
DE10351004A1 (de) * 2003-10-30 2005-05-25 Basf Ag Nanopartikuläre Wirkstoffformulierungen
GB0412631D0 (en) * 2004-06-07 2004-07-07 Cambridge Applied Polymers Ltd Polymer release system
ES2296187T3 (es) * 2004-06-08 2008-04-16 Basf Se Composiciones polimeras anfifilas y su empleo.
JP2006028059A (ja) * 2004-07-14 2006-02-02 Canon Inc Ｄｎａ固定体、この製造方法及びこれを用いた捕集システム
US20060047083A1 (en) * 2004-08-30 2006-03-02 Iskender Yilgor Triblock copolymers and their production methods
US8153706B2 (en) 2004-10-25 2012-04-10 Hewlett-Packard Development Company, L.P. Polymeric colorants having pigment and dye components and corresponding ink compositions
US20080045865A1 (en) * 2004-11-12 2008-02-21 Hanoch Kislev Nanoparticle Mediated Ultrasound Therapy and Diagnostic Imaging
IL165260A0 (en) * 2004-11-16 2005-12-18 Yissum Res Dev Co Polymeric nano-shells
CN101132800A (zh) * 2004-11-24 2008-02-27 席拉坎有限责任公司 一种用于眼内药物释出的植入体
TW200624464A (en) * 2004-12-31 2006-07-16 Ind Tech Res Inst Amphiphilic block copolymer and pharmaceutical formulation comprising the same
JP2006255536A (ja) * 2005-03-15 2006-09-28 Trans Parent:Kk ｐＨ応答性マイクロカプセルの調製方法
US20060224095A1 (en) 2005-04-05 2006-10-05 University Of New Hampshire Biocompatible polymeric vesicles self assembled from triblock copolymers
TWI274059B (en) * 2005-04-13 2007-02-21 Ind Tech Res Inst Novel thermo-responsive water soluble polymers for viscosity switch
WO2007028607A2 (de) * 2005-09-09 2007-03-15 Aesculap Ag & Co. Kg Antimikrobielles medizintechnisches produkt, verfahren zu seiner herstellung und verwendung
EP1945344A2 (de) * 2005-10-28 2008-07-23 Solarbre, Inc. Auf licht reagierende mikrokapselungswerkstoffe, zusammensetzungen daraus und verfahren zu ihrer verwendung
EA200802017A1 (ru) * 2006-03-21 2009-04-28 ДСМ АйПи АССЕТС Б.В. Микрочастицы, содержащие сшитый полимер
US7608646B1 (en) * 2006-04-28 2009-10-27 Hewlett-Packard Development Company, L.P. Polymer-encapsulated pigment with bridging layer
EP1813268A1 (de) * 2006-06-15 2007-08-01 DSMIP Assets B.V. Methode zur Herstellung von Polymermatrices durch Strahlen in Gegenwart empfindlicher pharmazeutischer Wirkstoffe
US7678838B2 (en) * 2006-08-04 2010-03-16 University Of Memphis Research Foundation Nanothin polymer films with selective pores and method of use thereof
US20080107744A1 (en) * 2006-11-06 2008-05-08 Jack Fa-De Chu Injectable hollow tissue filler
WO2008084571A1 (ja) * 2007-01-12 2008-07-17 Japan Science And Technology Agency 核酸応答性ゲルおよびその製造方法ならびにその利用
WO2008130641A1 (en) * 2007-04-20 2008-10-30 Biocure, Inc. Drug delivery vehicle containing vesicles in a hydrogel base
CA2686789C (en) * 2007-05-07 2013-11-19 Japan Science And Technology Agency Molecule-responsive gel fine particles, process for production of the same and use thereof
KR100868724B1 (ko) * 2007-05-30 2008-11-13 한국생산기술연구원 가역적 온도감응성을 가지는 자기집합성 나노운반체의제조방법
US20080305149A1 (en) * 2007-06-11 2008-12-11 Thomas Hirt Mucoadhesive vesicles for drug delivery
US7868059B2 (en) * 2007-07-27 2011-01-11 Hewlett-Packard Development Company, L.P. Polymerizable dye-monomer conjugates for encapsulating pigment particles
US8530244B2 (en) * 2007-10-02 2013-09-10 Terapia Celular, L'N, Inc. Methods and materials for amplification of a signal in an immunoassay
KR100990861B1 (ko) 2008-02-26 2010-11-01 주식회사 제닉 ｐＨ 응답성 폴리에틸렌 옥사이드계 공중합체 및 그 제조방법
US7897546B2 (en) * 2008-04-21 2011-03-01 Nalco Company Composition and method for recovering hydrocarbon fluids from a subterranean reservoir
RU2523714C2 (ru) * 2008-06-26 2014-07-20 Технише Универзитет Мюнхен Полимерные системы доставки действующих веществ
EP2151249A1 (de) * 2008-07-28 2010-02-10 Canon Kabushiki Kaisha PH-Indikator bestehend aus Polymer und Fluoreszenzfarbstoff
WO2010012816A1 (en) * 2008-07-31 2010-02-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Nanoparticles - external field effects
JP5326443B2 (ja) * 2008-09-05 2013-10-30 Ｊｎｃ株式会社 凍結乾燥可能な温度応答性磁性微粒子
CA2737452C (en) 2008-09-25 2018-05-22 Vive Nano Inc. Methods to produce polymer nanoparticles and formulations of active ingredients
US9457034B2 (en) * 2008-11-17 2016-10-04 The Hong Kong University Of Science And Technology Magnetic microsphere and method of forming a microsphere
CA2750815C (en) * 2009-02-09 2018-03-13 Swetree Technologies Ab Polymer shells
GB2470939A (en) 2009-06-10 2010-12-15 Dna Supernova Ltd Signal amplification microspheres
US9469839B2 (en) * 2009-06-29 2016-10-18 General Electric Company Cell culture support and associated method for cell growth and release
GB0922066D0 (en) 2009-12-17 2010-02-03 Univ Belfast Modulator
WO2011078457A2 (ko) * 2009-12-22 2011-06-30 성균관대학교산학협력단 다이온성 복합체 마이셀을 형성하는 피에이치 민감성 블록공중합체 및 이를 이용한 약물 또는 단백질 전달체
US7955301B1 (en) 2010-01-27 2011-06-07 Warsaw Orthopedic, Inc. Injection shut off valve with pressure actuator for delivery of compositions
US9050274B2 (en) * 2010-01-28 2015-06-09 Warsaw Orthopedic, Inc. Compositions and methods for treating an intervertebral disc using bulking agents or sealing agents
US9125902B2 (en) * 2010-01-28 2015-09-08 Warsaw Orthopedic, Inc. Methods for treating an intervertebral disc using local analgesics
US9486500B2 (en) 2010-01-28 2016-11-08 Warsaw Orthopedic, Inc. Osteoimplant and methods for making
EP2550337B1 (de) * 2010-03-24 2018-03-21 Vive Crop Protection Inc. Verfahren zur formulierung neutraler organischer verbindungen mit polymernanopartikeln
WO2012117588A1 (ja) 2011-02-28 2012-09-07 独立行政法人科学技術振興機構 複数物質応答性ゲルおよびその製造方法並びにその利用
WO2012154332A2 (en) * 2011-04-04 2012-11-15 William Marsh Rice University Stable nanoparticles for highly saline conditions
US9511077B2 (en) 2011-04-25 2016-12-06 Warsaw Orthopedic, Inc. Medical devices and methods comprising an anabolic agent for wound healing
US9592243B2 (en) 2011-04-25 2017-03-14 Warsaw Orthopedic, Inc. Medical devices and methods comprising an anabolic agent for treatment of an injury
WO2013009895A1 (en) * 2011-07-12 2013-01-17 Lawrence Livermore National Security, Llc Encapsulated tracers and chemicals for reservoir interrogation and manipulation
US9686979B2 (en) 2011-08-23 2017-06-27 Vive Crop Protection Inc. Pyrethroid formulations
CA2882679C (en) 2011-12-22 2019-10-15 Vive Crop Protection Inc. Strobilurin formulations
CN104023959B (zh) 2011-12-31 2016-08-03 诺华股份有限公司 具有识别标记的接触透镜
US9961900B2 (en) 2012-06-11 2018-05-08 Vive Crop Protection Inc. Herbicide formulations
US9392786B2 (en) 2013-02-05 2016-07-19 Vive Crop Protection, Inc. Mectin and milbemycin polyelectrolyte nanoparticle formulations
GR20130100654A (el) * 2013-11-22 2015-06-18 Χρηστος Γκολφινου Ταπεινος Επιφανειακως τροποποιημενα πολλαπλως αποκρινομενα σε ερεθισματα νανο/μικρο-δοχεια ως φορεις φαρμακων για στοχευμενη θεραπεια διαφορων μορφων καρκινου
US10080877B2 (en) 2014-07-25 2018-09-25 Warsaw Orthopedic, Inc. Drug delivery device and methods having a drug cartridge
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
KR102009969B1 (ko) * 2015-11-25 2019-10-21 주식회사 엘지화학 양친성 고분자
KR102184376B1 (ko) * 2015-11-25 2020-11-30 주식회사 엘지화학 양친성 고분자를 포함하는 미셀
KR101999947B1 (ko) * 2016-06-16 2019-07-15 주식회사 엘지화학 양친성 고분자
USD802755S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
CN107236078B (zh) * 2017-05-17 2019-10-29 南京工业大学 一种柔性软单体胶体光子晶体乳液的制备方法
EP3672411A4 (de) 2017-08-25 2021-05-19 Vive Crop Protection Inc. Mehrkomponentige, auf dem boden anwendbare pestizide zusammensetzungen
CA3152003A1 (en) * 2019-08-05 2021-02-11 University Of Tsukuba Hydrophilic-hydrophobic copolymer carrying short chain fatty acid ester
WO2021178988A1 (en) * 2020-03-04 2021-09-10 Siemens Healthcare Diagnostics Inc. Methods for amplifying immunoassay signals
KR102465931B1 (ko) * 2020-06-03 2022-11-14 한국원자력연구원 고분자-나노 입자 복합체 및 고분자-나노 입자 복합체의 제조 방법
CN114192079B (zh) * 2021-12-13 2022-09-30 广州光驭超材料有限公司 一种磁性中空聚合物微球及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60227826A (ja) * 1984-04-27 1985-11-13 Sogo Yatsukou Kk ｐＨに応答するグラフトカプセル
JPS6128440A (ja) * 1984-07-20 1986-02-08 Lion Corp ｐＨ感応性マイクロカプセルの製造方法
US4548955A (en) * 1985-02-25 1985-10-22 Sogo Pharmaceutical Company Limited Nylon capsule responding to pH
WO1988001213A1 (en) 1986-08-18 1988-02-25 Clinical Technologies Associates, Inc. Delivery systems for pharmacological agents
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
JP2711119B2 (ja) * 1988-12-01 1998-02-10 鐘紡株式会社 電気刺激による体積変化可能なマイクロカプセル
US5874316A (en) 1989-01-27 1999-02-23 Australian Membrane Biotechnology Research Institute Receptor membranes and ionophore gating
US5352461A (en) 1992-03-11 1994-10-04 Pharmaceutical Discovery Corporation Self assembling diketopiperazine drug delivery system
CA2153343A1 (en) 1993-01-11 1994-07-21 Valery Alexandrovich Dyatlov Small diameter nanocapsules, process for their preparation and applications thereof
WO1994017789A1 (en) 1993-02-15 1994-08-18 Shield Research Limited Polyalkylcyanoacrylate nanocapsules
JP3566336B2 (ja) * 1993-04-22 2004-09-15 鈴木油脂工業株式会社 ｐＨ感受溶解性マイクロカプセル及びこれを含有する化粧料
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
JPH11510837A (ja) 1995-07-28 1999-09-21 フォーカル，インコーポレイテッド 薬物送達のための制御された放出薬剤および組織処置薬剤としての使用のためのマルチブロック生分解性ヒドロゲル
DE69620898T2 (de) 1995-09-01 2002-11-07 University Of Washington, Seattle Interaktive molekulare konjugate
JP2000514791A (ja) 1996-06-27 2000-11-07 ジー．ディー．サール アンド カンパニー 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子
US5807944A (en) 1996-06-27 1998-09-15 Ciba Vision Corporation Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom
JP2945966B2 (ja) * 1997-09-08 1999-09-06 工業技術院長 ｐＨ感応性、感熱性マイクロビーズの製造方法
JP3584722B2 (ja) * 1998-02-13 2004-11-04 富士ゼロックス株式会社 高分子ゲル組成物、その製造方法及びそれを用いた光学素子

Also Published As

Publication number Publication date
EP1231905A2 (de) 2002-08-21
AU4304901A (en) 2001-06-04
CA2391660A1 (en) 2001-05-31
CA2391660C (en) 2009-11-24
EP1231905B1 (de) 2009-04-08
WO2001037803A3 (en) 2002-02-07
US6616946B1 (en) 2003-09-09
JP2003514650A (ja) 2003-04-22
DE60041978D1 (de) 2009-05-20
WO2001037803A2 (en) 2001-05-31

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