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ATE481099T1 - Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten - Google Patents

Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten

Info

Publication number
ATE481099T1
ATE481099T1 AT05798470T AT05798470T ATE481099T1 AT E481099 T1 ATE481099 T1 AT E481099T1 AT 05798470 T AT05798470 T AT 05798470T AT 05798470 T AT05798470 T AT 05798470T AT E481099 T1 ATE481099 T1 AT E481099T1
Authority
AT
Austria
Prior art keywords
muscarin
receptor antagonists
quinuclidine derivatives
quinuclidine
derivatives
Prior art date
Application number
AT05798470T
Other languages
German (de)
English (en)
Inventor
Neil Press
Stephen Collingwood
Urs Baettig
Brian Cox
Sudhakar Garad
Hyungchul Kim
Dimitris Papoutsakis
Simon Watson
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33515948&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE481099(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE481099T1 publication Critical patent/ATE481099T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT05798470T 2004-11-02 2005-10-31 Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten ATE481099T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0424284.8A GB0424284D0 (en) 2004-11-02 2004-11-02 Organic compounds
PCT/EP2005/011662 WO2006048225A1 (fr) 2004-11-02 2005-10-31 Derives de la quinuclidine et leur utilisation en tant qu'antagonistes du recepteur m3 muscarinique

Publications (1)

Publication Number Publication Date
ATE481099T1 true ATE481099T1 (de) 2010-10-15

Family

ID=33515948

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05798470T ATE481099T1 (de) 2004-11-02 2005-10-31 Chinuclidinderivate und deren verwendung als muscarin-m3-rezeptor-antagonisten

Country Status (33)

Country Link
US (2) US7723356B2 (fr)
EP (2) EP1811999B1 (fr)
JP (1) JP4950896B2 (fr)
KR (1) KR101252307B1 (fr)
CN (1) CN101056634B (fr)
AR (1) AR054090A1 (fr)
AT (1) ATE481099T1 (fr)
AU (1) AU2005300710B2 (fr)
BR (1) BRPI0517945A (fr)
CA (1) CA2583237C (fr)
CY (1) CY1110952T1 (fr)
DE (1) DE602005023639D1 (fr)
DK (1) DK1811999T3 (fr)
EC (1) ECSP077424A (fr)
ES (1) ES2353142T3 (fr)
GB (1) GB0424284D0 (fr)
HR (1) HRP20100693T1 (fr)
IL (1) IL182695A0 (fr)
JO (1) JO2613B1 (fr)
MA (1) MA29080B1 (fr)
MX (1) MX2007005189A (fr)
MY (1) MY145207A (fr)
NO (1) NO20072371L (fr)
NZ (1) NZ554302A (fr)
PE (1) PE20060609A1 (fr)
PL (1) PL1811999T3 (fr)
PT (1) PT1811999E (fr)
RU (1) RU2399620C2 (fr)
SI (1) SI1811999T1 (fr)
TN (1) TNSN07164A1 (fr)
TW (1) TW200628154A (fr)
WO (1) WO2006048225A1 (fr)
ZA (1) ZA200702772B (fr)

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US8329681B2 (en) 2005-08-11 2012-12-11 University Of Massachusetts Methods and compositions for the efficient delivery of therapeutic agents to cells and animals
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
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UA97492C2 (ru) * 2006-11-14 2012-02-27 Астразенека Аб Хиниклидиновые производные (гетеро) арилциклогептанкарбоксиловой кислоты как антагонисты мускаринового рецептора
TW200825084A (en) * 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
BRPI0721039A2 (pt) * 2006-12-19 2014-07-29 Astrazeneca Ab " derivados de quinuclidinol como antagonistas de receptores muscarínicos ".
BRPI0816219B8 (pt) 2007-09-07 2021-05-25 Theravance Biopharma R&D Ip Llc compostos contendo guanidina úteis como antagonistas de receptor muscarínico, composição farmacêutica e uso
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GB0808708D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New compounds 274
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US20120022127A1 (en) 2009-04-09 2012-01-26 Thomas Allmendinger Process for preparing pyrrolidinium salts
CN102947298B (zh) * 2010-06-22 2016-03-02 奇斯药制品公司 生物碱氨基酯衍生物及其药物组合物
WO2011160920A1 (fr) * 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Formulation de poudre sèche comprenant un médicament antimuscarinique
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (fr) 2010-09-09 2012-03-15 Irm Llc Composés et compositions comme inhibiteurs de trk
JP5959541B2 (ja) 2011-02-25 2016-08-02 ノバルティス アーゲー Ｔｒｋ阻害剤としてのピラゾロ［１，５−ａ］ピリジン
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
US9630945B2 (en) 2012-12-19 2017-04-25 Novartis Ag Autotaxin inhibitors
WO2015162558A1 (fr) 2014-04-24 2015-10-29 Novartis Ag Inhibiteurs de l'autotaxine
EP3139924A4 (fr) * 2014-05-06 2018-03-07 Anthony G. Visco Procédés de traitement ou de prévention du travail prématuré
CN109851615B (zh) * 2019-04-22 2021-06-08 上海旭东海普药业有限公司 纯化戊乙奎醚的方法

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MY145207A (en) 2012-01-13
CA2583237A1 (fr) 2006-05-11
US20100168132A1 (en) 2010-07-01
NZ554302A (en) 2009-12-24
US20090048281A1 (en) 2009-02-19
TW200628154A (en) 2006-08-16
MX2007005189A (es) 2007-05-11
CY1110952T1 (el) 2015-06-11
US8084463B2 (en) 2011-12-27
KR20070073849A (ko) 2007-07-10
EP1811999B1 (fr) 2010-09-15
RU2399620C2 (ru) 2010-09-20
JP4950896B2 (ja) 2012-06-13
KR101252307B1 (ko) 2013-04-08
RU2007120454A (ru) 2008-12-10
US7723356B2 (en) 2010-05-25
ES2353142T3 (es) 2011-02-25
SI1811999T1 (sl) 2011-01-31
PT1811999E (pt) 2010-10-29
CA2583237C (fr) 2013-01-22
IL182695A0 (en) 2007-09-20
PE20060609A1 (es) 2006-08-21
CN101056634A (zh) 2007-10-17
EP2206499A1 (fr) 2010-07-14
JP2008518890A (ja) 2008-06-05
EP1811999A1 (fr) 2007-08-01
ECSP077424A (es) 2007-05-30
JO2613B1 (ar) 2011-11-01
BRPI0517945A (pt) 2008-10-21
AR054090A1 (es) 2007-06-06
CN101056634B (zh) 2011-11-30
MA29080B1 (fr) 2007-12-03
AU2005300710B2 (en) 2009-05-14
ZA200702772B (en) 2008-08-27
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WO2006048225A1 (fr) 2006-05-11
AU2005300710A1 (en) 2006-05-11
NO20072371L (no) 2007-07-12
GB0424284D0 (en) 2004-12-01
TNSN07164A1 (en) 2008-11-21
HRP20100693T1 (hr) 2011-01-31

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