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ATE376596T1 - Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen - Google Patents

Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen

Info

Publication number
ATE376596T1
ATE376596T1 AT03742934T AT03742934T ATE376596T1 AT E376596 T1 ATE376596 T1 AT E376596T1 AT 03742934 T AT03742934 T AT 03742934T AT 03742934 T AT03742934 T AT 03742934T AT E376596 T1 ATE376596 T1 AT E376596T1
Authority
AT
Austria
Prior art keywords
disorders
analyzing
nucleic acids
cell proliferation
colorectal cell
Prior art date
Application number
AT03742934T
Other languages
English (en)
Inventor
Peter Adorjan
Matthias Burger
Sabine Maier
Ralf Lesche
Susan Cottrell
Vos Theo De
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Application granted granted Critical
Publication of ATE376596T1 publication Critical patent/ATE376596T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03742934T 2002-02-27 2003-02-13 Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen ATE376596T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02004551A EP1340818A1 (de) 2002-02-27 2002-02-27 Verfahren und Nukleinsäuren zur Analyse von Kolonkrebszellen

Publications (1)

Publication Number Publication Date
ATE376596T1 true ATE376596T1 (de) 2007-11-15

Family

ID=27675653

Family Applications (3)

Application Number Title Priority Date Filing Date
AT03742934T ATE376596T1 (de) 2002-02-27 2003-02-13 Verfahren und nukleinsäuren zur analyse von störungen der proliferation kolorektaler zellen
AT03742964T ATE491038T1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
AT03714760T ATE431429T1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebszellen

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT03742964T ATE491038T1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
AT03714760T ATE431429T1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebszellen

Country Status (9)

Country Link
US (6) US8691503B2 (de)
EP (4) EP1340818A1 (de)
JP (3) JP2005518218A (de)
AT (3) ATE376596T1 (de)
AU (3) AU2003210265A1 (de)
CA (1) CA2451982A1 (de)
DE (3) DE60317045T2 (de)
ES (2) ES2295607T3 (de)
WO (3) WO2003072812A2 (de)

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US20040029128A1 (en) * 2002-08-08 2004-02-12 Epigenomics, Inc. Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the calcitonin gene
US20080248536A1 (en) * 2004-01-23 2008-10-09 Lingvitae As Polynucleotide Ligation Reactions
US20090023134A1 (en) * 2004-03-17 2009-01-22 The Johns Hopkins University Neoplasia diagnostic compositions and methods of use
EP1778865A1 (de) * 2004-06-23 2007-05-02 Epigenomics AG Verfahren und nukleinsäuren zum nachweis der metastasierung proliferativer kolonzellerkrankungen
KR100617649B1 (ko) 2004-09-24 2006-09-04 (주)지노믹트리 대장암 특이적 발현감소 유전자의 메틸화된 프로모터를 함유하는 암 진단용 조성물 및 그 용도
ES2521115T3 (es) * 2004-09-30 2014-11-12 Epigenomics Ag Método para proveer fragmentos de ADN derivados de una muestra archivada
WO2006088978A1 (en) 2005-02-16 2006-08-24 Epigenomics, Inc. Method for determining the methylation pattern of a polynucleic acid
US7932027B2 (en) 2005-02-16 2011-04-26 Epigenomics Ag Method for determining the methylation pattern of a polynucleic acid
ATE547537T1 (de) 2005-04-15 2012-03-15 Epigenomics Ag Verfahren zur bestimmung der dna-methylierung in blut- oder urinproben
US20100143899A1 (en) * 2005-05-17 2010-06-10 University Of Vermont And State Agricultural College Methods and products for diagnosing cancer
US20080076134A1 (en) * 2006-09-21 2008-03-27 Nuclea Biomarkers, Llc Gene and protein expression profiles associated with the therapeutic efficacy of irinotecan
WO2008134020A1 (en) * 2007-04-26 2008-11-06 University Of Vermont And State Agricultural College Ccl18 and ccl3 methods and compositions for detecting and treating cancer
RU2499599C2 (ru) * 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
KR101622412B1 (ko) * 2007-10-19 2016-05-18 제넨테크, 인크. 시스테인 조작된 항-ｔｅｎｂ２ 항체 및 항체 약물 접합체
US20110098189A1 (en) * 2007-10-23 2011-04-28 Clinical Genomics Pty. Ltd. Method of diagnosing neoplasms - ii
KR100969692B1 (ko) * 2008-01-18 2010-07-14 한국생명공학연구원 대장암 과발현 유전자를 이용한 대장암 진단 마커
US20100112713A1 (en) * 2008-11-05 2010-05-06 The Texas A&M University System Methods For Detecting Colorectal Diseases And Disorders
CN102257161A (zh) * 2008-12-18 2011-11-23 皇家飞利浦电子股份有限公司 用于检测dna甲基化模式的方法
JP2014519310A (ja) 2011-02-02 2014-08-14 エクザクト サイエンシーズ コーポレイション Ｄｎａメチル化のデジタル配列分析
EP2768980B1 (de) 2011-10-17 2018-05-30 King Abdullah University Of Science And Technology Verbundbiomarker für nichtinvasives screening, diagnose und prognose von kolorektalkarzinom
US9598735B2 (en) * 2012-11-14 2017-03-21 JBS Science Inc. Detection of a panel of urine DNA markers for HCC screening and disease management
EP2886659A1 (de) 2013-12-20 2015-06-24 AIT Austrian Institute of Technology GmbH Genmethylierung basierend auf der Diagnose von Kolorektalkrebs

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Also Published As

Publication number Publication date
US20060246433A1 (en) 2006-11-02
CA2451982A1 (en) 2003-09-04
US9988683B2 (en) 2018-06-05
JP2005518220A (ja) 2005-06-23
US20110046005A1 (en) 2011-02-24
DE60335245D1 (de) 2011-01-20
WO2003072812A2 (en) 2003-09-04
AU2003248349B2 (en) 2008-05-01
JP2005518218A (ja) 2005-06-23
EP1340818A1 (de) 2003-09-03
EP1478784B1 (de) 2007-10-24
WO2003072820A3 (en) 2004-04-08
AU2003210265A1 (en) 2003-09-09
EP1481095B1 (de) 2010-12-08
EP1478778A2 (de) 2004-11-24
US20150275312A1 (en) 2015-10-01
US20060234224A1 (en) 2006-10-19
DE60317045T2 (de) 2008-08-07
WO2003072821A2 (en) 2003-09-04
ATE491038T1 (de) 2010-12-15
ES2325363T3 (es) 2009-09-02
JP2005518219A (ja) 2005-06-23
EP1481095A2 (de) 2004-12-01
AU2003248349A1 (en) 2003-09-09
AU2003219002B2 (en) 2008-04-24
WO2003072821A3 (en) 2004-04-01
US8691503B2 (en) 2014-04-08
ES2295607T3 (es) 2008-04-16
US20050003463A1 (en) 2005-01-06
US20140179563A1 (en) 2014-06-26
EP1478778B1 (de) 2009-05-13
WO2003072820A2 (en) 2003-09-04
DE60317045D1 (de) 2007-12-06
ATE431429T1 (de) 2009-05-15
WO2003072812A3 (en) 2003-10-23
DE60327600D1 (de) 2009-06-25
EP1478784A2 (de) 2004-11-24
AU2003219002A1 (en) 2003-09-09

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