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ATE236126T1 - Metalloproteinase inhibitoren - Google Patents

Metalloproteinase inhibitoren

Info

Publication number
ATE236126T1
ATE236126T1 AT97912351T AT97912351T ATE236126T1 AT E236126 T1 ATE236126 T1 AT E236126T1 AT 97912351 T AT97912351 T AT 97912351T AT 97912351 T AT97912351 T AT 97912351T AT E236126 T1 ATE236126 T1 AT E236126T1
Authority
AT
Austria
Prior art keywords
methoxysuccinamide
pyridin
isobutyl
propyl
hydroxy
Prior art date
Application number
AT97912351T
Other languages
English (en)
Inventor
Raymond Paul Beckett
Mark Whittaker
Andrew Miller
Fionna Mitchell Martin
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Application granted granted Critical
Publication of ATE236126T1 publication Critical patent/ATE236126T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97912351T 1997-11-13 1997-11-13 Metalloproteinase inhibitoren ATE236126T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1997/003132 WO1999025693A1 (en) 1997-11-13 1997-11-13 Metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
ATE236126T1 true ATE236126T1 (de) 2003-04-15

Family

ID=10807699

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97912351T ATE236126T1 (de) 1997-11-13 1997-11-13 Metalloproteinase inhibitoren

Country Status (21)

Country Link
EP (1) EP1030842B1 (de)
JP (1) JP2001523666A (de)
KR (1) KR100485479B1 (de)
AT (1) ATE236126T1 (de)
AU (1) AU740420B2 (de)
BR (1) BR9714934A (de)
CA (1) CA2310593C (de)
DE (1) DE69720554T2 (de)
DK (1) DK1030842T3 (de)
ES (1) ES2195122T3 (de)
GB (1) GB2333524A (de)
HU (1) HUP0002811A3 (de)
IL (1) IL135210A0 (de)
NO (1) NO315702B1 (de)
NZ (1) NZ503642A (de)
PL (1) PL189542B1 (de)
PT (1) PT1030842E (de)
RU (1) RU2198164C2 (de)
TR (1) TR200001353T2 (de)
TW (1) TW474919B (de)
WO (1) WO1999025693A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69515702T2 (de) * 1994-01-20 2000-08-10 British Biotech Pharmaceuticals Ltd., Cowley L-Tertiär-leucin-2-pyridylamid
AU2986295A (en) * 1995-07-19 1997-02-18 British Biotech Pharmaceuticals Limited N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors

Also Published As

Publication number Publication date
WO1999025693A1 (en) 1999-05-27
NZ503642A (en) 2001-10-26
CA2310593A1 (en) 1999-05-27
HUP0002811A3 (en) 2002-11-28
HUP0002811A2 (hu) 2001-01-29
EP1030842A1 (de) 2000-08-30
GB9816317D0 (en) 1998-09-23
IL135210A0 (en) 2001-05-20
PT1030842E (pt) 2003-07-31
CA2310593C (en) 2007-05-08
NO315702B1 (no) 2003-10-13
PL189542B1 (pl) 2005-08-31
AU4958497A (en) 1999-06-07
EP1030842B1 (de) 2003-04-02
TR200001353T2 (tr) 2000-10-23
BR9714934A (pt) 2000-10-03
DE69720554T2 (de) 2004-01-08
ES2195122T3 (es) 2003-12-01
KR100485479B1 (ko) 2005-04-27
GB2333524A (en) 1999-07-28
KR20010031879A (ko) 2001-04-16
NO20002480D0 (no) 2000-05-12
PL340494A1 (en) 2001-02-12
RU2198164C2 (ru) 2003-02-10
JP2001523666A (ja) 2001-11-27
TW474919B (en) 2002-02-01
NO20002480L (no) 2000-05-12
AU740420B2 (en) 2001-11-01
DK1030842T3 (da) 2003-07-28
DE69720554D1 (de) 2003-05-08

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