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ATE295847T1 - Aktivsauerstoffaufnehmer enthaltende pterinderivate - Google Patents

Aktivsauerstoffaufnehmer enthaltende pterinderivate

Info

Publication number
ATE295847T1
ATE295847T1 AT97933848T AT97933848T ATE295847T1 AT E295847 T1 ATE295847 T1 AT E295847T1 AT 97933848 T AT97933848 T AT 97933848T AT 97933848 T AT97933848 T AT 97933848T AT E295847 T1 ATE295847 T1 AT E295847T1
Authority
AT
Austria
Prior art keywords
group
active oxygen
pterine
supporters
containing active
Prior art date
Application number
AT97933848T
Other languages
English (en)
Inventor
Toshiyuki Arai
Keisuke Makino
Kenjiro Mori
Original Assignee
Cmic Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cmic Co Ltd filed Critical Cmic Co Ltd
Application granted granted Critical
Publication of ATE295847T1 publication Critical patent/ATE295847T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97933848T 1996-07-31 1997-07-30 Aktivsauerstoffaufnehmer enthaltende pterinderivate ATE295847T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21804396 1996-07-31
PCT/JP1997/002649 WO1998004558A1 (fr) 1996-07-31 1997-07-30 Piegeurs d'oxygene actifs a base de derives de pterine

Publications (1)

Publication Number Publication Date
ATE295847T1 true ATE295847T1 (de) 2005-06-15

Family

ID=16713759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97933848T ATE295847T1 (de) 1996-07-31 1997-07-30 Aktivsauerstoffaufnehmer enthaltende pterinderivate

Country Status (10)

Country Link
US (1) US6162806A (de)
EP (1) EP0884317B1 (de)
KR (1) KR19990063880A (de)
CN (1) CN1084332C (de)
AT (1) ATE295847T1 (de)
AU (1) AU739069B2 (de)
DE (1) DE69733308D1 (de)
IL (1) IL123884A (de)
NZ (1) NZ330078A (de)
WO (1) WO1998004558A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
WO2000039129A1 (en) * 1998-12-28 2000-07-06 K.U. Leuven Research & Development Immunosuppressive effects of pteridine derivatives
JP2007511536A (ja) 2003-11-17 2007-05-10 バイオマリン ファーマシューティカル インコーポレイテッド 代謝障害の処置のための方法及び組成物
CN101132776A (zh) 2004-11-17 2008-02-27 生物马林药物股份有限公司 稳定的四氢生物喋呤片剂制剂
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
WO2008009078A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
CA2675134A1 (en) * 2007-01-12 2008-07-24 Biomarin Pharmaceutical Inc. Pterin analogs
KR100882340B1 (ko) * 2007-03-30 2009-02-11 주식회사 래디안 테리딘이 유효성분으로 포함된 나노리포좀 함유 화장료 조성물 및 그 제조방법
RU2470642C2 (ru) * 2008-01-03 2012-12-27 Байомарин Фармасьютикл Инк. Аналоги птерина для лечения состояния, чувствительного к вн4
WO2011159471A2 (en) * 2010-06-18 2011-12-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Linked purine pterin hppk inhibitors useful as antibacterial agents
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
US10316167B2 (en) 2014-09-19 2019-06-11 Plastipak Packaging Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
HUE050029T2 (hu) 2015-03-04 2020-11-30 Gilead Sciences Inc 4,6-Diamino-pirido[3,2-d]pirimidin-származékok és alkalmazásuk toll-szerû receptorok modulátoraként
EP3507288B1 (de) 2016-09-02 2020-08-26 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidinderivate als toll-like-rezeptor modulatoren
MA46093A (fr) 2016-09-02 2021-05-19 Gilead Sciences Inc Composés modulateurs du recepteur de type toll
CA3039997A1 (en) 2016-10-11 2018-04-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hppk inhibitors useful as antibacterial agents
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994303A (en) * 1988-03-21 1991-02-19 Garlock, Inc. Fiber impregnation process
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
DE4418096A1 (de) * 1994-05-24 1995-11-30 Cassella Ag Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase
WO1996003989A1 (fr) * 1994-08-05 1996-02-15 Suntory Limited Remede contre la degenerescence spino-cerebelleuse
ES2210562T5 (es) * 1996-08-30 2007-11-16 Asubio Pharma Co., Ltd Preparaciones que sirven para la prevencion y el tratamiento de enfermedades provocadas por una hipofuncion del oxido nitrico sintasa.

Also Published As

Publication number Publication date
DE69733308D1 (de) 2005-06-23
NZ330078A (en) 2000-01-28
CN1198161A (zh) 1998-11-04
KR19990063880A (ko) 1999-07-26
CN1084332C (zh) 2002-05-08
IL123884A0 (en) 1998-10-30
US6162806A (en) 2000-12-19
EP0884317A2 (de) 1998-12-16
EP0884317A4 (de) 1999-04-14
IL123884A (en) 2002-04-21
EP0884317B1 (de) 2005-05-18
AU3707197A (en) 1998-02-20
WO1998004558A1 (fr) 1998-02-05
AU739069B2 (en) 2001-10-04

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