ATE258T1 - Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte. - Google Patents

Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte.

Info

Publication number: ATE258T1
Authority: AT; Austria
Prior art keywords: tetrahydroisochinoline; dichloro; manufacture; intermediate products; products
Prior art date: 1978-08-10

Application number

AT79102847T

Other languages

English (en)

Inventor

Bing Lun Lam

Wilford Lee Mendelson

Charles Barton Spainhour Jr

Original Assignee

Smithkline Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-08-10

Filing date

1979-08-07

Publication date

1981-10-15

1979-08-07 Application filed by Smithkline Corporation filed Critical Smithkline Corporation

1981-10-15 Application granted granted Critical

1981-10-15 Publication of ATE258T1 publication Critical patent/ATE258T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Obesity (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT79102847T 1978-08-10 1979-08-07 Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte. ATE258T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/932,586 US4251660A (en)	1978-08-10	1978-08-10	Method for preparing tetrahydroisoquinolines
EP79102847A EP0008405B1 (de)	1978-08-10	1979-08-07	Verfahren zur Herstellung von 7,8-Dichlor-1,2,3,4-tetrahydroisochinolin und Zwischenprodukte

Publications (1)

Publication Number	Publication Date
ATE258T1 true ATE258T1 (de)	1981-10-15

Family

ID=25462546

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT79102847T ATE258T1 (de)	1978-08-10	1979-08-07	Verfahren zur herstellung von 7,8-dichlor-1,2,3,4-tetrahydroisochinolin und zwischenprodukte.

Country Status (29)

Country	Link
US (1)	US4251660A (de)
EP (1)	EP0008405B1 (de)
JP (1)	JPS5524196A (de)
AR (1)	AR220218A1 (de)
AT (1)	ATE258T1 (de)
AU (1)	AU522843B2 (de)
BG (1)	BG32714A3 (de)
CA (1)	CA1130290A (de)
CS (1)	CS226006B2 (de)
DD (1)	DD145532A5 (de)
DE (1)	DE2961141D1 (de)
DK (1)	DK330579A (de)
ES (1)	ES483151A1 (de)
FI (1)	FI65062C (de)
GR (1)	GR69853B (de)
HU (1)	HU178110B (de)
IE (1)	IE48618B1 (de)
IL (1)	IL57980A (de)
IN (1)	IN152421B (de)
IT (1)	IT1227791B (de)
MX (1)	MX5581E (de)
NO (1)	NO153807C (de)
NZ (1)	NZ191227A (de)
PH (1)	PH24441A (de)
PL (1)	PL217684A1 (de)
PT (1)	PT70029A (de)
RO (1)	RO78160A (de)
SU (1)	SU860698A3 (de)
ZA (1)	ZA793308B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3272044D1 (de) *	1981-11-27	1986-08-21	Smithkline Beckman Corp	3-benzazepines as alpha-2 antagonists
US4541954A (en) *	1984-09-05	1985-09-17	Smithkline Beckman Corporation	Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2771468A (en) *	1954-02-19	1956-11-20	Sterling Drug Inc	4-aralkyl-3-morpholones, 4-aralkyl-3-homomorpholones and their preparation
US3947456A (en) *	1970-01-06	1976-03-30	Hoffman-La Roche Inc.	Substituted 4-phenyl isoquinolines
US3752892A (en) *	1970-03-11	1973-08-14	Ciba Geigy Corp	Anorexigenic tetrahydrobenzazepine derivative method and composition thereof

1978
- 1978-08-10 US US05/932,586 patent/US4251660A/en not_active Expired - Lifetime
1979
- 1979-06-27 IN IN470/DEL/79A patent/IN152421B/en unknown
- 1979-07-03 ZA ZA793308A patent/ZA793308B/xx unknown
- 1979-08-02 IT IT7924894A patent/IT1227791B/it active
- 1979-08-03 AR AR277592A patent/AR220218A1/es active
- 1979-08-03 CA CA333,200A patent/CA1130290A/en not_active Expired
- 1979-08-03 PH PH22859A patent/PH24441A/en unknown
- 1979-08-03 AU AU49547/79A patent/AU522843B2/en not_active Ceased
- 1979-08-06 IL IL57980A patent/IL57980A/xx unknown
- 1979-08-06 PT PT70029A patent/PT70029A/pt unknown
- 1979-08-06 GR GR59778A patent/GR69853B/el unknown
- 1979-08-06 ES ES483151A patent/ES483151A1/es not_active Expired
- 1979-08-06 NZ NZ191227A patent/NZ191227A/xx unknown
- 1979-08-06 FI FI792436A patent/FI65062C/fi not_active IP Right Cessation
- 1979-08-07 DE DE7979102847T patent/DE2961141D1/de not_active Expired
- 1979-08-07 AT AT79102847T patent/ATE258T1/de not_active IP Right Cessation
- 1979-08-07 DK DK330579A patent/DK330579A/da not_active Application Discontinuation
- 1979-08-07 JP JP10115279A patent/JPS5524196A/ja active Pending
- 1979-08-07 EP EP79102847A patent/EP0008405B1/de not_active Expired
- 1979-08-08 RO RO7998406A patent/RO78160A/ro unknown
- 1979-08-09 CS CS795460A patent/CS226006B2/cs unknown
- 1979-08-09 DD DD79214893A patent/DD145532A5/de unknown
- 1979-08-09 IE IE1534/79A patent/IE48618B1/en unknown
- 1979-08-09 HU HU79SI1715A patent/HU178110B/hu unknown
- 1979-08-09 NO NO792601A patent/NO153807C/no unknown
- 1979-08-10 SU SU792798064A patent/SU860698A3/ru active
- 1979-08-10 MX MX798312U patent/MX5581E/es unknown
- 1979-08-10 PL PL21768479A patent/PL217684A1/xx unknown
- 1979-08-10 BG BG044609A patent/BG32714A3/xx unknown

Also Published As

Publication number	Publication date
GR69853B (de)	1982-07-19
IN152421B (de)	1984-01-07
PL217684A1 (de)	1980-06-16
AR220218A1 (es)	1980-10-15
ZA793308B (en)	1980-09-24
FI792436A (fi)	1980-02-11
AU522843B2 (en)	1982-07-01
PH24441A (en)	1990-06-25
IT1227791B (it)	1991-05-07
EP0008405B1 (de)	1981-09-30
FI65062B (fi)	1983-11-30
DD145532A5 (de)	1980-12-17
CA1130290A (en)	1982-08-24
IL57980A0 (en)	1979-12-30
FI65062C (fi)	1984-03-12
DK330579A (da)	1980-02-11
NZ191227A (en)	1981-10-19
EP0008405A3 (en)	1980-04-30
CS226006B2 (en)	1984-03-19
NO153807B (no)	1986-02-17
JPS5524196A (en)	1980-02-21
NO153807C (no)	1986-05-28
SU860698A3 (ru)	1981-08-30
DE2961141D1 (en)	1981-12-10
IE791534L (en)	1980-02-10
HU178110B (en)	1982-03-28
PT70029A (en)	1979-09-01
RO78160A (ro)	1982-02-01
IL57980A (en)	1984-08-31
ES483151A1 (es)	1980-04-16
BG32714A3 (en)	1982-09-15
AU4954779A (en)	1980-02-14
NO792601L (no)	1980-02-12
IT7924894A0 (it)	1979-08-02
US4251660A (en)	1981-02-17
IE48618B1 (en)	1985-03-20
EP0008405A2 (de)	1980-03-05
MX5581E (es)	1983-10-26

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Legal Events

Date	Code	Title	Description
1982-05-15	UEP	Publication of translation of european patent specification
1986-05-15	REN	Ceased due to non-payment of the annual fee