[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ATE256661T1 - Bispiperidine mit antithrombotischer wirkung - Google Patents

Bispiperidine mit antithrombotischer wirkung

Info

Publication number
ATE256661T1
ATE256661T1 AT99929495T AT99929495T ATE256661T1 AT E256661 T1 ATE256661 T1 AT E256661T1 AT 99929495 T AT99929495 T AT 99929495T AT 99929495 T AT99929495 T AT 99929495T AT E256661 T1 ATE256661 T1 AT E256661T1
Authority
AT
Austria
Prior art keywords
bispiperidine
antithrombotic effect
antithrombotic
therepeutically
fibrinogen
Prior art date
Application number
AT99929495T
Other languages
English (en)
Inventor
Christophe Yue
Marguerite Henry
Thierry Giboulot
Brigitte Lesur
Original Assignee
Cephalon France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon France filed Critical Cephalon France
Application granted granted Critical
Publication of ATE256661T1 publication Critical patent/ATE256661T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT99929495T 1998-07-17 1999-07-16 Bispiperidine mit antithrombotischer wirkung ATE256661T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9809166A FR2781223B1 (fr) 1998-07-17 1998-07-17 Bispiperidines et leurs applications therapeutiques
PCT/FR1999/001745 WO2000003986A1 (fr) 1998-07-17 1999-07-16 Bispiperidines comme agents antithrombotiques

Publications (1)

Publication Number Publication Date
ATE256661T1 true ATE256661T1 (de) 2004-01-15

Family

ID=9528732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99929495T ATE256661T1 (de) 1998-07-17 1999-07-16 Bispiperidine mit antithrombotischer wirkung

Country Status (25)

Country Link
US (1) US6333338B1 (de)
EP (1) EP1098878B1 (de)
JP (1) JP2002520393A (de)
KR (1) KR100584032B1 (de)
CN (1) CN1286812C (de)
AT (1) ATE256661T1 (de)
AU (1) AU761655B2 (de)
BR (1) BR9912835A (de)
CA (1) CA2337776A1 (de)
DE (1) DE69913701T2 (de)
DK (1) DK1098878T3 (de)
EA (1) EA003674B1 (de)
ES (1) ES2212576T3 (de)
FR (1) FR2781223B1 (de)
HU (1) HUP0103623A3 (de)
IL (2) IL140581A0 (de)
NO (1) NO318963B1 (de)
NZ (1) NZ509170A (de)
PL (1) PL193804B1 (de)
PT (1) PT1098878E (de)
SK (1) SK152001A3 (de)
TR (1) TR200100159T2 (de)
UA (1) UA65631C2 (de)
WO (1) WO2000003986A1 (de)
ZA (1) ZA200100238B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001047874A1 (en) * 1999-12-24 2001-07-05 Smithkline Beecham P.L.C. (hetero)bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives
CA2529486A1 (en) * 2003-06-18 2004-12-23 Nst Neurosurvival Technologies Ltd. Method for selective targeting of apoptotic cells and small molecule ligands used thereof
BR112021026410A2 (pt) 2019-07-01 2022-02-08 Tonix Pharma Ltd Anticorpos anti-cd154 e usos dos mesmos
CA3207098A1 (en) 2021-01-06 2022-07-14 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ239876A (en) * 1990-09-27 1993-12-23 Merck & Co Inc Glycyl-b-alanine derivatives and pharmaceutical compositions thereof.

Also Published As

Publication number Publication date
NO20010252L (no) 2001-03-19
EP1098878B1 (de) 2003-12-17
TR200100159T2 (tr) 2001-06-21
IL140581A0 (en) 2002-02-10
HUP0103623A3 (en) 2003-01-28
DE69913701D1 (de) 2004-01-29
FR2781223B1 (fr) 2000-10-13
EA003674B1 (ru) 2003-08-28
PT1098878E (pt) 2004-04-30
SK152001A3 (en) 2001-11-06
US6333338B1 (en) 2001-12-25
CA2337776A1 (en) 2000-01-27
KR100584032B1 (ko) 2006-05-29
EP1098878A1 (de) 2001-05-16
ZA200100238B (en) 2001-11-21
ES2212576T3 (es) 2004-07-16
BR9912835A (pt) 2001-10-09
PL193804B1 (pl) 2007-03-30
NZ509170A (en) 2004-01-30
NO318963B1 (no) 2005-05-30
DE69913701T2 (de) 2004-10-21
AU761655B2 (en) 2003-06-05
EA200100150A1 (ru) 2001-08-27
NO20010252D0 (no) 2001-01-15
FR2781223A1 (fr) 2000-01-21
PL345418A1 (en) 2001-12-17
DK1098878T3 (da) 2004-02-16
CN1312799A (zh) 2001-09-12
WO2000003986A1 (fr) 2000-01-27
UA65631C2 (en) 2004-04-15
JP2002520393A (ja) 2002-07-09
CN1286812C (zh) 2006-11-29
AU4629099A (en) 2000-02-07
KR20010071925A (ko) 2001-07-31
IL140581A (en) 2006-12-31
HUP0103623A2 (hu) 2002-02-28

Similar Documents

Publication Publication Date Title
PT892780E (pt) Analogos de m-amidino fenilo como inibidores do factor xa
TR199701356A2 (xx) L�kozit adhasyonu inhibit�rleri ve VLA-4-antagonistleri olarak heterosiklenler.
EA200300171A1 (ru) Циклопентаноиндолы, композиции, содержащие данные соединения, и способы лечения
ES2160408T3 (es) Trifluorfenil-triazolpirimidinas fungicidas.
NO20034291D0 (no) 2-aminopropanolderivater
CR8193A (es) Piperazina con o sustituida de grupos feniles y su uso como inhibidores de glyt 1
ES2146774T3 (es) Polimeros de ioneno que contienen aniones biologicamente activos.
EA199900381A1 (ru) Арил(тио)эфиры галогенпиримидина в качестве пестицидов
DE69328072D1 (de) Umweltfreundliche Zusammensetzungen zur Verbesserung des Viskositätsindexes
ME00562B (me) Novi oblik soli pantoprazola
BG103558A (en) Sulphonic acid or sulphonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
FI954556A (fi) Syklisiä yhdisteitä, jotka ovat käyttökelpoisia verihiutaleen glykoproteiinin IIb/IIIa inhibiittoreina
SE9801494D0 (sv) Novel use
SE9903290D0 (sv) Novel compounds
ATE256661T1 (de) Bispiperidine mit antithrombotischer wirkung
DE60139770D1 (de) Hydantoin derivate mit affinität für somatostatin rezeptoren
EA200200798A1 (ru) Кальцилитические соединения
EA200100853A1 (ru) Резорциновая композиция
EA200100152A1 (ru) Замещенные пиперазиноны и их терапевтическое применение
EA200100151A1 (ru) Производные пиперазинона и их применение
DE60043228D1 (de) Herstellungsverfahren von 2-cyanopyridinen
ATE213236T1 (de) Substituierte benzyloxyimino-verbindungen
ATE135586T1 (de) Verwendung von transferrin zur bekämpfung der toxischen wirkung des endotoxins bei der endotoxinämie
EA200100299A1 (ru) Уреидопиперидиновые производные как селективные антагонисты nk3 - рецепторов человека
BR0114872A (pt) 3-nitroisoxazol e seu emprego na proteção de materiais

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1098878

Country of ref document: EP

REN Ceased due to non-payment of the annual fee