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ATE174796T1 - Neue verfahren zur progesteronabgabe - Google Patents

Neue verfahren zur progesteronabgabe

Info

Publication number
ATE174796T1
ATE174796T1 AT94928089T AT94928089T ATE174796T1 AT E174796 T1 ATE174796 T1 AT E174796T1 AT 94928089 T AT94928089 T AT 94928089T AT 94928089 T AT94928089 T AT 94928089T AT E174796 T1 ATE174796 T1 AT E174796T1
Authority
AT
Austria
Prior art keywords
progesterone
serum
low levels
new methods
serum progesterone
Prior art date
Application number
AT94928089T
Other languages
English (en)
Inventor
William Joseph Bologna
Howard Leslie Levine
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402302&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE174796(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Application granted granted Critical
Publication of ATE174796T1 publication Critical patent/ATE174796T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94928089T 1993-09-15 1994-09-13 Neue verfahren zur progesteronabgabe ATE174796T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/122,371 US5543150A (en) 1993-09-15 1993-09-15 Method of progesterone delivery and affect thereof

Publications (1)

Publication Number Publication Date
ATE174796T1 true ATE174796T1 (de) 1999-01-15

Family

ID=22402302

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94928089T ATE174796T1 (de) 1993-09-15 1994-09-13 Neue verfahren zur progesteronabgabe

Country Status (27)

Country Link
US (1) US5543150A (de)
EP (1) EP0719146B1 (de)
JP (1) JP3143474B2 (de)
KR (1) KR100278553B1 (de)
AT (1) ATE174796T1 (de)
BR (1) BR9407475A (de)
CA (1) CA2171939C (de)
CO (1) CO4290332A1 (de)
DE (1) DE69415543T2 (de)
DK (1) DK0719146T3 (de)
ES (1) ES2126783T3 (de)
FI (1) FI115444B (de)
GR (1) GR3029314T3 (de)
HU (1) HU221583B (de)
IL (1) IL110972A (de)
LT (1) LT4072B (de)
LV (1) LV11527B (de)
MA (1) MA23329A1 (de)
MY (1) MY111484A (de)
NO (1) NO308585B1 (de)
NZ (1) NZ273816A (de)
PE (1) PE50795A1 (de)
PH (1) PH30813A (de)
RU (1) RU2148393C1 (de)
UA (1) UA37244C2 (de)
WO (1) WO1995007699A1 (de)
ZA (1) ZA947073B (de)

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US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
EP1356806A1 (de) * 1997-09-12 2003-10-29 Columbia Laboratories (Bermuda) Limited Arzneimittel zur Behandlung von Dysmenorrhöe und verfrühten Wehen
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
AU9449398A (en) * 1997-10-10 1999-05-03 Imperial College Innovations Ltd. Use of csaidtm compounds for the management of uterine contractions
US6306914B1 (en) * 1997-10-21 2001-10-23 Columbia Laboratories, Inc. Progestin therapy for maintaining amenorrhea
WO1999059595A1 (en) * 1998-05-20 1999-11-25 Wiley Teresa S Progesterone treatment of cancer
US20070178139A1 (en) * 1998-11-18 2007-08-02 Yankov Vladimir I Vaginally administratable progesterone-containing tablets and method for preparing same
IL127129A (en) * 1998-11-18 2004-06-01 Ferring Bv Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
US6544553B1 (en) * 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
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US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
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CN1845723B (zh) * 2003-09-03 2010-07-21 迷斯康贸易有限公司 子宫内膜异位症的治疗方法
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CN101237851B (zh) * 2005-06-16 2013-09-18 沃纳奇尔科特有限责任公司 用于阴道给药的雌激素组合物
EP1898880A2 (de) * 2005-06-16 2008-03-19 Warner Chilcott Company Inc. Gelzusammensetzungen zur topischen verabreichung
CA2654152A1 (en) * 2006-06-02 2007-12-13 Pear Tree Women's Health Care Method of treating atrophic vaginitis
US8828981B2 (en) * 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
ES2310968B1 (es) 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
US8003621B2 (en) * 2007-09-14 2011-08-23 Nitto Denko Corporation Drug carriers
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
GB0723882D0 (en) * 2007-12-07 2008-01-23 Univ Leicester Methods for the detection of a threatened miscarriage
KR20100133969A (ko) 2008-02-04 2010-12-22 테바 위민즈 헬스 인코포레이티드 프로게스테론 함유 단일형 질내 링 및 그의 제조방법과 용도
US9107696B2 (en) 2008-08-06 2015-08-18 Emory University Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
US8421747B2 (en) 2008-09-24 2013-04-16 Microsoft Corporation Object detection and user settings
ES2344675B1 (es) 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
KR20130009990A (ko) * 2010-03-22 2013-01-24 레프로스 쎄라피우틱스 아이엔씨. 항프로게스틴의 비독성 전달을 위한 조성물들과 그 방법들
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8435972B2 (en) 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
WO2013010915A1 (en) * 2011-07-15 2013-01-24 Universiteit Gent Intravaginal delivery system
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
EP2806742B1 (de) * 2012-01-26 2019-03-27 TherapeuticsMD, Inc. Transdermale hormonersatztherapien
CN104334158B (zh) 2012-05-31 2018-08-10 利普生物药剂公司 经阴道递送抗孕素的调配物和方法
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
WO2014070517A1 (en) 2012-11-02 2014-05-08 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103239389A (zh) * 2013-06-03 2013-08-14 南京泽恒医药技术开发有限公司 一种治疗先兆性流产的黄体酮缓释凝胶的制备方法
US10206932B2 (en) 2014-05-22 2019-02-19 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3174542A4 (de) 2014-07-29 2018-01-03 TherapeuticsMD, Inc. Transdermale creme
WO2016210003A2 (en) 2015-06-22 2016-12-29 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
MX2018011705A (es) 2016-04-01 2019-06-10 Therapeuticsmd Inc Composicion farmaceutica de hormona esteroide.
GB2581876B (en) * 2017-06-22 2023-05-31 Viramal Ltd Compositions for use in the treatment of endometrial disorder
EP3659583B1 (de) 2018-11-30 2023-06-07 Viramal Limited Verfahren zur herstellung eines geliermittels, das dadurch erhaltene geliermittel und verwendung dieses geliermittels
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Also Published As

Publication number Publication date
DK0719146T3 (da) 1999-08-23
FI115444B (fi) 2005-05-13
FI961221A0 (fi) 1996-03-15
AU689133B2 (en) 1998-03-26
JP3143474B2 (ja) 2001-03-07
KR100278553B1 (ko) 2001-01-15
MY111484A (en) 2000-06-30
HUT76824A (en) 1997-11-28
MA23329A1 (fr) 1995-04-01
US5543150A (en) 1996-08-06
AU7726194A (en) 1995-04-03
DE69415543D1 (de) 1999-02-04
IL110972A (en) 1998-03-10
EP0719146B1 (de) 1998-12-23
LV11527A (lv) 1996-10-20
WO1995007699A1 (en) 1995-03-23
FI961221A (fi) 1996-05-14
LT4072B (en) 1996-11-25
ES2126783T3 (es) 1999-04-01
LT96027A (en) 1996-07-25
NO308585B1 (no) 2000-10-02
UA37244C2 (uk) 2001-05-15
ZA947073B (en) 1995-05-02
EP0719146A1 (de) 1996-07-03
CA2171939A1 (en) 1995-03-23
GR3029314T3 (en) 1999-05-28
IL110972A0 (en) 1994-11-28
NO961044L (no) 1996-05-14
DE69415543T2 (de) 1999-06-17
CA2171939C (en) 2002-01-01
CO4290332A1 (es) 1996-04-17
LV11527B (en) 1997-02-20
JPH09502724A (ja) 1997-03-18
PE50795A1 (es) 1996-01-19
NZ273816A (en) 2007-09-28
NO961044D0 (no) 1996-03-14
BR9407475A (pt) 1996-11-12
HU221583B (hu) 2002-11-28
HU9600669D0 (en) 1996-05-28
RU2148393C1 (ru) 2000-05-10
PH30813A (en) 1997-10-17

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