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ATE150087T1 - Esterase-gene, esterase, rekombinante plasmide und diese enthaltende transformanten, und verfahren zur herstellung von optisch aktiver karbonsäure und ihrer enantiomeren ester durch diese transformanten - Google Patents

Esterase-gene, esterase, rekombinante plasmide und diese enthaltende transformanten, und verfahren zur herstellung von optisch aktiver karbonsäure und ihrer enantiomeren ester durch diese transformanten

Info

Publication number
ATE150087T1
ATE150087T1 AT92108205T AT92108205T ATE150087T1 AT E150087 T1 ATE150087 T1 AT E150087T1 AT 92108205 T AT92108205 T AT 92108205T AT 92108205 T AT92108205 T AT 92108205T AT E150087 T1 ATE150087 T1 AT E150087T1
Authority
AT
Austria
Prior art keywords
esterase
transformants
optically active
carboxylic acid
producing optically
Prior art date
Application number
AT92108205T
Other languages
English (en)
Inventor
Eiji Ozaki
Sakimae Akihiro
Numazawa Ryozo
Original Assignee
Mitsubishi Rayon Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP24992391A external-priority patent/JP2763213B2/ja
Application filed by Mitsubishi Rayon Co filed Critical Mitsubishi Rayon Co
Application granted granted Critical
Publication of ATE150087T1 publication Critical patent/ATE150087T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92108205T 1991-05-15 1992-05-15 Esterase-gene, esterase, rekombinante plasmide und diese enthaltende transformanten, und verfahren zur herstellung von optisch aktiver karbonsäure und ihrer enantiomeren ester durch diese transformanten ATE150087T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP11062891 1991-05-15
JP11062991 1991-05-15
JP24992391A JP2763213B2 (ja) 1991-05-15 1991-09-27 光学活性カルボン酸及びその対掌体エステルの製造法
JP26613691 1991-10-15

Publications (1)

Publication Number Publication Date
ATE150087T1 true ATE150087T1 (de) 1997-03-15

Family

ID=27469836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92108205T ATE150087T1 (de) 1991-05-15 1992-05-15 Esterase-gene, esterase, rekombinante plasmide und diese enthaltende transformanten, und verfahren zur herstellung von optisch aktiver karbonsäure und ihrer enantiomeren ester durch diese transformanten

Country Status (6)

Country Link
US (2) US5308765A (de)
EP (1) EP0513806B1 (de)
KR (1) KR100232552B1 (de)
AT (1) ATE150087T1 (de)
CA (1) CA2068614C (de)
DE (1) DE69218034T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0765857B1 (de) * 1994-06-13 1999-12-08 Mitsubishi Rayon Co., Ltd. Verfahren zur herstellung von optisch aktiven alpha-substituierten carbonsäurederivaten
ATE169866T1 (de) * 1995-02-15 1998-09-15 Schablonentechnik Kufstein Ag Verfahren zur herstellung einer siebdruckschablone
US6218163B1 (en) 1995-08-07 2001-04-17 Thermogen, Inc. Stable biocatalysts for ester hydrolysis
EP0952847A4 (de) * 1996-01-11 2003-09-03 Thermogen Inc Stabile biokatalysatoren für die esterhydrolyse
DE60044276D1 (de) * 1999-06-04 2010-06-10 Sumitomo Chemical Co Esterase Gene und Verwendungen davon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0130752B1 (de) * 1983-07-04 1991-02-27 Mitsubishi Rayon Co., Ltd. Verfahren zur Herstellung von optisch aktiven Carbonsäuren und von Antipodenestern
JPS6012993A (ja) * 1983-07-04 1985-01-23 Mitsubishi Rayon Co Ltd 光学活性カルボン酸の製造法
JPH0632633B2 (ja) * 1983-07-04 1994-05-02 三菱レイヨン株式会社 光学活性カルボン酸の製造法
GB8600245D0 (en) * 1986-01-07 1986-02-12 Shell Int Research Preparation of 2-arylpropionic acids
US5030240A (en) * 1986-06-09 1991-07-09 The Clorox Company Enzymatic peracid bleaching system
AU621813B2 (en) * 1986-11-19 1992-03-26 Genencor Inc. Novel hydrolase and method
JP2516777B2 (ja) * 1987-09-09 1996-07-24 日東化学工業株式会社 カルボン酸エステルを不斉加水分解する酵素の遺伝子を有する組換え体プラスミド、それにより形質転換された微生物および該微生物による光学活性カルボン酸の製造法
JP2638853B2 (ja) * 1987-11-05 1997-08-06 スズキ株式会社 船外機の排気装置
JPH0632635B2 (ja) * 1988-02-29 1994-05-02 三菱レイヨン株式会社 光学活性カルボン酸及びその対掌体エステルの製造法
CA2023892A1 (en) * 1989-08-24 1991-02-25 Hardy W. Chan Cloning, expression and sequencing of an ester hydrolase gene in escherichia coli
JPH0714342B2 (ja) * 1990-08-10 1995-02-22 田辺製薬株式会社 エステラーゼの製法

Also Published As

Publication number Publication date
DE69218034D1 (de) 1997-04-17
CA2068614C (en) 2003-12-16
KR100232552B1 (ko) 1999-12-01
EP0513806A1 (de) 1992-11-19
KR920021710A (ko) 1992-12-18
CA2068614A1 (en) 1992-11-16
EP0513806B1 (de) 1997-03-12
US5308765A (en) 1994-05-03
US5482847A (en) 1996-01-09
DE69218034T2 (de) 1997-06-19

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