AT350748B - Verfahren zur herstellung von neuen d-17alpha- aethinyl-17beta-acyloxy-19-nortestosteron-3- oximen - Google Patents

Verfahren zur herstellung von neuen d-17alpha- aethinyl-17beta-acyloxy-19-nortestosteron-3- oximen

Info

Publication number: AT350748B
Authority: AT; Austria
Prior art keywords: aethinyl; oximen; nortestosterone; 17alpha; 17beta
Prior art date: 1975-07-24

Application number

AT543976A

Other languages

English (en)

Other versions

ATA543976A (de

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-07-24

Filing date

1976-07-23

Publication date

1979-06-11

1976-07-23 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1978-11-15 Publication of ATA543976A publication Critical patent/ATA543976A/de

1979-06-11 Application granted granted Critical

1979-06-11 Publication of AT350748B publication Critical patent/AT350748B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Fertilizers (AREA)

AT543976A 1975-07-24 1976-07-23 Verfahren zur herstellung von neuen d-17alpha- aethinyl-17beta-acyloxy-19-nortestosteron-3- oximen AT350748B (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59896675A	1975-07-24	1975-07-24
US05/652,000 US4027019A (en)	1975-07-24	1976-01-23	3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method

Publications (2)

Publication Number	Publication Date
ATA543976A ATA543976A (de)	1978-11-15
AT350748B true AT350748B (de)	1979-06-11

Family

ID=27083202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT543976A AT350748B (de)	1975-07-24	1976-07-23	Verfahren zur herstellung von neuen d-17alpha- aethinyl-17beta-acyloxy-19-nortestosteron-3- oximen

Country Status (22)

Country	Link
US (1)	US4027019A (de)
JP (1)	JPS5214760A (de)
AT (1)	AT350748B (de)
AU (1)	AU501808B2 (de)
CA (1)	CA1072948A (de)
CH (1)	CH599249A5 (de)
DE (2)	DE2633210C2 (de)
DK (1)	DK145610C (de)
ES (1)	ES450108A1 (de)
FI (1)	FI55036C (de)
FR (1)	FR2318645A1 (de)
GB (1)	GB1557197A (de)
IE (1)	IE43581B1 (de)
IL (1)	IL50103A (de)
MX (1)	MX3417E (de)
NL (1)	NL192206C (de)
NO (1)	NO143350C (de)
NZ (1)	NZ181130A (de)
PH (1)	PH12003A (de)
PT (1)	PT65402B (de)
SE (2)	SE421800B (de)
YU (1)	YU39968B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4507290A (en) *	1981-04-07	1985-03-26	World Health Organization	Esters of 17 α-ethynyl 19-nor-testosterone and 17 α-ethynyl-18-homo-19-nor-testosterone and pharmaceutical compositions containing the same
GB8313921D0 (en) *	1983-05-19	1983-06-22	World Health Org	Contraceptive compositions
WO1993013122A1 (de) *	1991-12-22	1993-07-08	Schering Aktiengesellschaft	3-methylsulfonylhydrazono- und 3-oxyimino-steroide, ein verfahren zu deren herstellung, diese steroide enthaltende pharmazeutische präparate sowie ihre verwendung zur herstellung von arzneimitteln
US7989436B2 (en)	2003-07-23	2011-08-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and pharmaceutical formulations comprising the same
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7459445B2 (en) *	2000-03-10	2008-12-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and topical pharmaceutical formulations of the same
US6660726B2 (en)	2000-03-10	2003-12-09	Endeavor Pharmaceuticals	Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US20050143360A1 (en) *	2001-02-02	2005-06-30	Joel Krasnow	Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
MXPA05010871A (es) *	2003-04-11	2005-11-25	Barr Lab Inc	Metodos para administrar estrogenos y progestinas.
AR039733A1 (es) *	2003-06-25	2005-03-09	Gador Sa	Proceso para la obtencion de norelgestromin en distintas relaciones de los isomeros e y z
HUP0301981A2 (hu) *	2003-06-30	2005-04-28	Richter Gedeon Vegyészeti Gyár Rt.	Tiszta d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-3E- és 3Z-oxim izomerek, valamint eljárás az izomer keverékek és a tiszta izomerek előállítására
US7816546B2 (en) *	2003-06-30	2010-10-19	Richter Gedeon Vegyeszeti Gyar Rt.	Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
HUP0301982A2 (hu) *	2003-06-30	2005-04-28	Richter Gedeon Vegyészeti Gyár Rt.	Eljárás nagy tisztaságú d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-oxim előállítására
EP1778716A1 (de) *	2004-08-12	2007-05-02	Sicor Inc.	Verfahren zur herstellung von 3-oximino-steroiden
EP1853272A1 (de) *	2005-02-03	2007-11-14	Duramed Pharmaceuticals, Inc.	Zusammensetzungen aus unkonjugierten östrogenen und anwendungsverfahren dafür

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1493161B2 (de) *	1951-01-28	1973-08-30		17alpha-aethinyl-18-methyl-19nortestosteronester, verfahren zu ihrer herstellung und diese enthaltendes mittel
US3780073A (en) *	1966-07-06	1973-12-18	Ortho Pharma Corp	3-oximes of 19-nortestosterone esters
US3532689A (en) *	1967-04-20	1970-10-06	Ortho Pharma Corp	3-oxime and 3-oxime esters of 19-nortestosterone
NL7306609A (de) *	1972-05-26	1973-11-28
US3912768A (en) *	1972-09-26	1975-10-14	Warner Lambert Co	Norethindrone O-alkyloximes

1976
- 1976-01-23 US US05/652,000 patent/US4027019A/en not_active Expired - Lifetime
- 1976-06-11 NZ NZ181130A patent/NZ181130A/en unknown
- 1976-06-14 PH PH18572A patent/PH12003A/en unknown
- 1976-06-14 FR FR7617973A patent/FR2318645A1/fr active Granted
- 1976-06-15 GB GB24769/76A patent/GB1557197A/en not_active Expired
- 1976-06-28 AU AU15357/76A patent/AU501808B2/en not_active Expired
- 1976-07-06 CA CA256,343A patent/CA1072948A/en not_active Expired
- 1976-07-13 YU YU1733/76A patent/YU39968B/xx unknown
- 1976-07-22 CH CH940376A patent/CH599249A5/xx not_active IP Right Cessation
- 1976-07-22 IL IL50103A patent/IL50103A/xx unknown
- 1976-07-22 JP JP51086661A patent/JPS5214760A/ja active Granted
- 1976-07-22 MX MX001792U patent/MX3417E/es unknown
- 1976-07-23 NL NL7608210A patent/NL192206C/nl not_active IP Right Cessation
- 1976-07-23 AT AT543976A patent/AT350748B/de not_active IP Right Cessation
- 1976-07-23 ES ES450108A patent/ES450108A1/es not_active Expired
- 1976-07-23 DE DE2633210A patent/DE2633210C2/de not_active Expired
- 1976-07-23 IE IE1636/76A patent/IE43581B1/en unknown
- 1976-07-23 SE SE7608407A patent/SE421800B/xx not_active IP Right Cessation
- 1976-07-23 FI FI762116A patent/FI55036C/fi not_active IP Right Cessation
- 1976-07-23 DK DK335876A patent/DK145610C/da not_active IP Right Cessation
- 1976-07-23 PT PT65402A patent/PT65402B/pt unknown
- 1976-07-23 NO NO762583A patent/NO143350C/no unknown
- 1976-07-23 DE DE2661002A patent/DE2661002C2/de not_active Expired
1979
- 1979-12-14 SE SE7910336A patent/SE445458B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE43581B1 (en)	1981-04-08
PT65402A (en)	1976-08-01
FI55036C (fi)	1979-05-10
ES450108A1 (es)	1977-11-16
IE43581L (en)	1977-01-24
CA1072948A (en)	1980-03-04
DK145610C (da)	1983-08-01
SE7608407L (sv)	1977-01-25
NO143350C (no)	1981-01-28
DK335876A (da)	1977-01-25
DE2661002C2 (de)	1988-03-17
NL7608210A (nl)	1977-01-26
IL50103A0 (en)	1976-09-30
US4027019A (en)	1977-05-31
JPS5214760A (en)	1977-02-03
DE2633210A1 (de)	1977-02-17
DK145610B (da)	1982-12-27
PH12003A (en)	1978-10-06
IL50103A (en)	1979-11-30
CH599249A5 (de)	1978-05-31
AU1535776A (en)	1978-01-05
NZ181130A (en)	1984-07-06
NO762583L (de)	1977-01-25
SE445458B (sv)	1986-06-23
PT65402B (en)	1979-06-09
YU39968B (en)	1985-06-30
NL192206C (nl)	1997-03-04
DE2633210C2 (de)	1987-04-09
FI55036B (fi)	1979-01-31
NL192206B (nl)	1996-11-01
NO143350B (no)	1980-10-13
FR2318645A1 (fr)	1977-02-18
JPS624400B2 (de)	1987-01-30
YU173376A (en)	1982-08-31
SE7910336L (sv)	1979-12-14
DE2661002A1 (de)	1985-05-02
FR2318645B1 (de)	1978-11-17
SE421800B (sv)	1982-02-01
MX3417E (es)	1980-11-13
FI762116A (de)	1977-01-25
AU501808B2 (en)	1979-06-28
ATA543976A (de)	1978-11-15
GB1557197A (en)	1979-12-05

Publication	Publication Date	Title
ATA162876A (de)	1977-12-15	Verfahren zur herstellung von neuen piperazinyliminorifamycinen
DD132663A5 (de)	1978-10-18	Verfahren zur herstellung von neuen penicillansaeurederivaten
AT350748B (de)	1979-06-11	Verfahren zur herstellung von neuen d-17alpha- aethinyl-17beta-acyloxy-19-nortestosteron-3- oximen
DD128782A5 (de)	1977-12-07	Verfahren zur herstellung von n-alkyldiphenylaminen
AT344147B (de)	1978-07-10	Verfahren zur herstellung von acylcyaniden
ATA314576A (de)	1979-01-15	Verfahren zur herstellung von 4-nideralkyl-5- cyano-oxazolen
AT349032B (de)	1979-03-12	Verfahren zur herstellung von 4-alkyl-thiosemicarbaziden
AT333749B (de)	1976-12-10	Verfahren zur herstellung von neuen 2-arylamino-2-imidazolinderivaten
DD132435A5 (de)	1978-09-27	Verfahren zur herstellung von indolochinolizinen
AT342078B (de)	1978-03-10	Verfahren zur herstellung von neuen vinylthionophosphorsaureestern
AT354441B (de)	1979-01-10	Verfahren zur herstellung von neuen 1- benzthiazolyl-imidazolidinonen
AT354442B (de)	1979-01-10	Verfahren zur herstellung von neuen 1- thiazolyl-imidazolidinonen
AT347452B (de)	1978-12-27	Verfahren zur herstellung von neuen 1- thiadiazolyl-5-acyloxy-imidazolidin-2-onen
AT343682B (de)	1978-06-12	Verfahren zur herstellung von neuen o-pyrazolopyrimidinthionothiolphosphorsaureestern
AT352714B (de)	1979-10-10	Verfahren zur herstellung von neuen nitroimi- dazolylvinylthiadiazolen
ATA976775A (de)	1977-09-15	Verfahren zur herstellung von neuen n-benzoyl-n-phenyl-sulfensaureamiden
AT339920B (de)	1977-11-10	Verfahren zur herstellung von neuen bis-triarylphosphoniumsalzen
AT345782B (de)	1978-10-10	Verfahren zur herstellung von n-phenyl-5-chlor- 2-nitranilin
AT337673B (de)	1977-07-11	Verfahren zur herstellung von neuen 1-aminoalkyl-2-ary-cyclohexanolen
AT342555B (de)	1978-04-10	Verfahren zur herstellung von neuen 2-methyl-3-buten-3-halogen-2-olen
AT349476B (de)	1979-04-10	Verfahren zur herstellung von neuen phenoxy- alkancarbonsaeurederivaten von 1-cinnamyl-4- diphenylmethylpiperazin
ATA517075A (de)	1979-07-15	Verfahren zur herstellung von neuen 3- acylamino-2-azetidinonderivaten
ATA846777A (de)	1978-03-15	Verfahren zur herstellung von neuen oxadiazin-derivaten
AT343137B (de)	1978-05-10	Verfahren zur herstellung von neuen n-acyl-n-alkylaminomethandiphosphonsauren
ATA911976A (de)	1977-03-15	Verfahren zur herstellung von neuen bis-triarylphosphoniumsalzen

Legal Events

Date	Code	Title	Description
1997-09-15	ELA	Expired due to lapse of time