AR222309A1 - Procedimiento para la elaboracion de 1,3-diaza-ciclo-pent-2-eno(2,1-b)-(1-tia-3-aza-cicloalcanos) - Google Patents

Procedimiento para la elaboracion de 1,3-diaza-ciclo-pent-2-eno(2,1-b)-(1-tia-3-aza-cicloalcanos)

Info

Publication number: AR222309A1
Authority: AR; Argentina
Prior art keywords: cicloalcanos; ciclo; eno; diaza; tia
Prior art date: 1977-07-07

Application number

AR272843A

Other languages

English (en)

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-07

Filing date

1978-07-05

Publication date

1981-05-15

1978-07-05 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1981-05-15 Application granted granted Critical

1981-05-15 Publication of AR222309A1 publication Critical patent/AR222309A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AR272843A 1977-07-07 1978-07-05 Procedimiento para la elaboracion de 1,3-diaza-ciclo-pent-2-eno(2,1-b)-(1-tia-3-aza-cicloalcanos) AR222309A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
LU77703A LU77703A1 (de)	1977-07-07	1977-07-07	Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen

Publications (1)

Publication Number	Publication Date
AR222309A1 true AR222309A1 (es)	1981-05-15

Family

ID=19728633

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AR272843A AR222309A1 (es)	1977-07-07	1978-07-05	Procedimiento para la elaboracion de 1,3-diaza-ciclo-pent-2-eno(2,1-b)-(1-tia-3-aza-cicloalcanos)
AR279136A AR224381A1 (es)	1977-07-07	1979-12-03	Procedimiento para la elaboracion de 1,3-diazaciclopent-2-eno(2,1-b)(1-tia-3-aza-cicloalcanos)

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AR279136A AR224381A1 (es)	1977-07-07	1979-12-03	Procedimiento para la elaboracion de 1,3-diazaciclopent-2-eno(2,1-b)(1-tia-3-aza-cicloalcanos)

Country Status (18)

Country	Link
EP (3)	EP0020858A1 (es)
JP (1)	JPS5416470A (es)
AR (2)	AR222309A1 (es)
AU (1)	AU3778878A (es)
DD (2)	DD145538A5 (es)
DK (1)	DK305578A (es)
ES (4)	ES471458A1 (es)
FI (1)	FI782132A (es)
GR (1)	GR64978B (es)
IL (1)	IL55086A0 (es)
IT (1)	IT8149647A0 (es)
LU (1)	LU77703A1 (es)
NO (1)	NO782357L (es)
NZ (1)	NZ187789A (es)
PL (1)	PL116596B1 (es)
PT (1)	PT68246A (es)
SU (4)	SU873886A3 (es)
ZA (1)	ZA783898B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0004648B1 (de) *	1978-04-11	1982-08-25	Ciba-Geigy Ag	Neue Mercaptoimidazolderivate, Verfahren zu deren Herstellung, Mercaptoimidazolderivate zur Behandlung entzündlicher Erkrankungen und diese enthaltende pharmazeutische Präparate
DE2823197A1 (de) *	1978-05-24	1979-11-29	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4175127A (en) *	1978-09-27	1979-11-20	Smithkline Corporation	Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
PL221188A1 (es) *	1979-01-05	1980-12-01	Ciba Geigy Ag
US4636516A (en) *	1981-02-19	1987-01-13	Yamanouchi Pharmaceutical Co., Ltd.	3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds
IL78834A (en) *	1985-05-23	1992-07-15	Smithkline Beckman Corp	2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines
US4803279A (en) *	1985-05-23	1989-02-07	Smithkline Beckman Corporation	1.4-dihydro-4-pyridyl-substituted imidazo (2,1-b) thiazoles and the corresponding thiazines.
US5008390A (en) *	1985-05-23	1991-04-16	Smithkline Beckman Corporation	Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines
ZW24186A1 (en) *	1985-12-12	1987-07-08	Smithkline Beckman Corp	Inhibition of the 5-lipoxygenase pathway
US4719218A (en) *	1985-12-12	1988-01-12	Smithkline Beckman Corporation	Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor
WO1991000092A1 (en) *	1989-06-13	1991-01-10	Smithkline Beecham Corporation	Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages
GB9005966D0 (en) *	1990-03-16	1990-05-09	May & Baker Ltd	New compositions of matter
GB9019838D0 (en) *	1990-09-11	1990-10-24	Smith Kline French Lab	Compounds
CA2063865A1 (en) *	1992-03-24	1993-09-25	Karoly Lempert	2-(substituted imino)-thiazolidines and process for the preparation thereof
US5552422A (en) *	1995-01-11	1996-09-03	Merck Frosst Canada, Inc.	Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2981739A (en) *	1958-01-27	1961-04-25	Diamond Alkali Co	Certain alpha-haloaldehyde addition products of ethylenethioureas and process
NL131034C (es) *	1964-05-11
US3297708A (en) *	1965-10-06	1967-01-10	American Cyanamid Co	Method of preparing thiazolidines
US3455924A (en) *	1967-02-08	1969-07-15	Upjohn Co	Dianisylimidazoles
NL164285C (nl) *	1968-01-09	1980-12-15	Rhone Poulenc Sa	Werkwijze ter bereiding van een farmaceutisch preparaat, dat een imidazoÿ2.1-bÿthiazoolderivaat bevat, de gevormde farmaceutische preparaten, alsmede werkwijze voor het bereiden van dit imidazoÿ2.1-bÿthiazoolderivaat.
BE788792A (fr) *	1971-09-30	1973-03-13	Ici Ltd	Procedes et compositions a usage anti-bacterien
US3842097A (en) *	1973-01-22	1974-10-15	Searle & Co	2-(phenoxyalkylthio)imidazoles and congeners
SE428686B (sv) *	1975-08-11	1983-07-18	Du Pont	Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler
GB1541321A (en) *	1976-03-10	1979-02-28	Metabio	2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
US4064260A (en) *	1976-07-29	1977-12-20	E. I. Du Pont De Nemours And Company	Anti-inflammatory diarylimidazothiazoles and their corresponding S-oxides
US4263311A (en) *	1976-09-27	1981-04-21	Smithkline Corporation	5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles

1977
- 1977-07-07 LU LU77703A patent/LU77703A1/de unknown
1978
- 1978-06-29 EP EP80101322A patent/EP0020858A1/de not_active Withdrawn
- 1978-06-29 EP EP78100272A patent/EP0000353A3/xx not_active Withdrawn
- 1978-06-29 EP EP80101323A patent/EP0019688A1/de not_active Ceased
- 1978-07-03 PT PT68246A patent/PT68246A/pt unknown
- 1978-07-03 FI FI782132A patent/FI782132A/fi not_active Application Discontinuation
- 1978-07-05 AU AU37788/78A patent/AU3778878A/en active Pending
- 1978-07-05 IL IL55086A patent/IL55086A0/xx unknown
- 1978-07-05 AR AR272843A patent/AR222309A1/es active
- 1978-07-05 GR GR56695A patent/GR64978B/el unknown
- 1978-07-05 ES ES471458A patent/ES471458A1/es not_active Expired
- 1978-07-06 NO NO782357A patent/NO782357L/no unknown
- 1978-07-06 DK DK783055A patent/DK305578A/da unknown
- 1978-07-06 NZ NZ187789A patent/NZ187789A/xx unknown
- 1978-07-06 SU SU782632647A patent/SU873886A3/ru active
- 1978-07-06 DD DD78214990A patent/DD145538A5/de unknown
- 1978-07-06 ZA ZA00783898A patent/ZA783898B/xx unknown
- 1978-07-06 DD DD78206565A patent/DD138212A5/xx unknown
- 1978-07-06 JP JP8153378A patent/JPS5416470A/ja active Pending
- 1978-07-07 PL PL1978208253A patent/PL116596B1/pl unknown
1979
- 1979-03-05 ES ES478296A patent/ES478296A1/es not_active Expired
- 1979-05-18 SU SU792763599A patent/SU893134A3/ru active
- 1979-09-10 ES ES484033A patent/ES484033A1/es not_active Expired
- 1979-09-20 ES ES484327A patent/ES484327A1/es not_active Expired
- 1979-10-23 SU SU792831085A patent/SU850007A3/ru active
- 1979-12-03 AR AR279136A patent/AR224381A1/es active
- 1979-12-20 SU SU792855458A patent/SU873887A3/ru active
1981
- 1981-11-06 IT IT8149647A patent/IT8149647A0/it unknown

Also Published As

Publication number	Publication date
FI782132A (fi)	1979-01-08
NZ187789A (en)	1981-03-16
ES484327A1 (es)	1980-05-16
AR224381A1 (es)	1981-11-30
AU3778878A (en)	1980-01-10
DD138212A5 (de)	1979-10-17
EP0020858A1 (de)	1981-01-07
NO782357L (no)	1979-01-09
JPS5416470A (en)	1979-02-07
ES484033A1 (es)	1980-04-16
ES471458A1 (es)	1979-10-01
PL116596B1 (en)	1981-06-30
IT8149647A0 (it)	1981-11-06
DK305578A (da)	1979-01-08
SU873886A3 (ru)	1981-10-15
SU873887A3 (ru)	1981-10-15
EP0019688A1 (de)	1980-12-10
IL55086A0 (en)	1978-09-29
EP0000353A3 (en)	1979-06-13
SU893134A3 (ru)	1981-12-23
EP0000353A2 (de)	1979-01-24
PL208253A1 (pl)	1979-06-04
GR64978B (en)	1980-06-11
DD145538A5 (de)	1980-12-17
PT68246A (en)	1978-08-01
LU77703A1 (de)	1979-03-26
ES478296A1 (es)	1979-05-16
ZA783898B (en)	1979-07-25
SU850007A3 (ru)	1981-07-23

Publication	Publication Date	Title
AR219560A1 (es)	1980-08-29	Procedimiento para la preparacion de derivados de 5,5-dimetil-hidantoina
ES493330A0 (es)	1981-11-16	Procedimiento para la obtencion de nikkomicinas de efecto pesticida
AR222309A1 (es)	1981-05-15	Procedimiento para la elaboracion de 1,3-diaza-ciclo-pent-2-eno(2,1-b)-(1-tia-3-aza-cicloalcanos)
AR216937A1 (es)	1980-02-15	Procedimiento para la preparacion de 1,1,1,2-tetrafluoretano
AR227527A1 (es)	1982-11-15	Procedimiento para la elaboracion de nuevos compuestos n-oxaciclilalquil-piperidil-diazoicos
MX5529E (es)	1983-09-23	Procedimiento para la preparacion de indolo-(2,3-a)-quinolizidinas
AR229175A1 (es)	1983-06-30	Procedimiento para la elaboracion de 2,3-dicloro-5-triclorometilpiridina
ES493650A0 (es)	1981-07-01	Procedimiento para la fabricacion de 2(3,4,5-trimetoxifenil)tiazoles,4,5-disubstituidos
MX5256E (es)	1983-05-23	Procedimiento para la preparacion de derivados de 20,21-dinoreburnamenina
AR220120A1 (es)	1980-10-15	Procedimiento para la fabricacion de derivados de 1-alquil-4-(n-acetil)amino-tetrahidro-1,3,5-triazol-2,6-diona
AR225889A1 (es)	1982-05-14	Procedimiento para la elaboracion de acidos heterociclilcarboxilicos acilados
ES490988A0 (es)	1980-12-16	Procedimiento para la obtencion de butirolactona
ES490475A0 (es)	1981-08-16	Procedimiento para la obtencion de metilolaminotriazinas eteradas
MX7052E (es)	1987-04-08	Procedimiento para la preparacion de 2-metoxi-4-amino-5-alquilsulfonil-n-(3-beta-8-azabiciclo-(3,2,1)octil)-benzamidas
AR225415A1 (es)	1982-03-31	Procedimiento para la obtencion de nuevos derivados de pirido(2,1-b)quinazolina
AR223319A1 (es)	1981-08-14	Procedimiento para la elaboracion de compuestos de 6-amino-penam
MX6009E (es)	1984-09-24	Procedimiento para la preparacion de tetrahidro-1,3,5-tiadiazin-4-onas
MX5933E (es)	1984-08-30	Procedimiento para la preparacion de 4,5-diciclo-2-(tiosubstituidos)-imidazoles
ES488810A0 (es)	1981-02-16	Procedimiento para la obtencion de diazatriciclos
AR230835A1 (es)	1984-07-31	Procedimiento para la obtencion de derivados de 2,1,3-tiadiazin-4-ona-2,2-dioxido
MX147950A (es)	1983-02-10	Procedimiento mejorado para la preparacion de tiofenoles
ES513169A0 (es)	1984-07-01	Procedimiento para la obtencion de nuevos derivados de benzazol.
ES507983A0 (es)	1982-10-01	Procedimiento para la obtencion de derivados de 2-amino-etanol.
ES493649A0 (es)	1981-06-01	Procedimiento para la fabricacion de 4-tiazolidonas,2-subs- tituidas
MX4991E (es)	1983-01-31	Procedimiento para la preparacion de 2,4,diamino-5-tiobencilpirimidinas