ZA783898B - Bicyclic thiadiaza compounds and process for their production - Google Patents

Bicyclic thiadiaza compounds and process for their production

Info

Publication number: ZA783898B
Authority: ZA; South Africa
Prior art keywords: thiadiaza; bicyclic; compounds; production; thiadiaza compounds
Prior art date: 1977-07-07

Application number

ZA00783898A

Inventor

P Ferrini

R Goeschke

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-07

Filing date

1978-07-06

Publication date

1979-07-25

1978-07-06 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1979-07-25 Publication of ZA783898B publication Critical patent/ZA783898B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA00783898A 1977-07-07 1978-07-06 Bicyclic thiadiaza compounds and process for their production ZA783898B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
LU77703A LU77703A1 (en)	1977-07-07	1977-07-07	METHOD FOR PRODUCING BICYCLIC THIA-DIAZA COMPOUNDS

Publications (1)

Publication Number	Publication Date
ZA783898B true ZA783898B (en)	1979-07-25

Family

ID=19728633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00783898A ZA783898B (en)	1977-07-07	1978-07-06	Bicyclic thiadiaza compounds and process for their production

Country Status (18)

Country	Link
EP (3)	EP0020858A1 (en)
JP (1)	JPS5416470A (en)
AR (2)	AR222309A1 (en)
AU (1)	AU3778878A (en)
DD (2)	DD138212A5 (en)
DK (1)	DK305578A (en)
ES (4)	ES471458A1 (en)
FI (1)	FI782132A (en)
GR (1)	GR64978B (en)
IL (1)	IL55086A0 (en)
IT (1)	IT8149647A0 (en)
LU (1)	LU77703A1 (en)
NO (1)	NO782357L (en)
NZ (1)	NZ187789A (en)
PL (1)	PL116596B1 (en)
PT (1)	PT68246A (en)
SU (4)	SU873886A3 (en)
ZA (1)	ZA783898B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0004648B1 (en) *	1978-04-11	1982-08-25	Ciba-Geigy Ag	Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
DE2823197A1 (en) *	1978-05-24	1979-11-29	Schering Ag	NEW IMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
US4175127A (en) *	1978-09-27	1979-11-20	Smithkline Corporation	Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
FI800005A (en) *	1979-01-05	1980-07-06	Ciba Geigy Ag	FRAMEWORK FOR BICYCLING THREAD SALES
US4636516A (en) *	1981-02-19	1987-01-13	Yamanouchi Pharmaceutical Co., Ltd.	3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds
US5008390A (en) *	1985-05-23	1991-04-16	Smithkline Beckman Corporation	Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines
US4803279A (en) *	1985-05-23	1989-02-07	Smithkline Beckman Corporation	1.4-dihydro-4-pyridyl-substituted imidazo (2,1-b) thiazoles and the corresponding thiazines.
IL78834A (en) *	1985-05-23	1992-07-15	Smithkline Beckman Corp	2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines
US4719218A (en) *	1985-12-12	1988-01-12	Smithkline Beckman Corporation	Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor
ZW24186A1 (en) *	1985-12-12	1987-07-08	Smithkline Beckman Corp	Inhibition of the 5-lipoxygenase pathway
AU6355190A (en) *	1989-06-13	1991-01-17	Smithkline Beecham Corporation	Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages
GB9005966D0 (en) *	1990-03-16	1990-05-09	May & Baker Ltd	New compositions of matter
GB9019838D0 (en) *	1990-09-11	1990-10-24	Smith Kline French Lab	Compounds
US5240918A (en) *	1992-03-24	1993-08-31	Egis Gyogyszergyar	2-(substituted imino)-thiazolidines and process for the preparation thereof
US5552422A (en) *	1995-01-11	1996-09-03	Merck Frosst Canada, Inc.	Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2981739A (en) *	1958-01-27	1961-04-25	Diamond Alkali Co	Certain alpha-haloaldehyde addition products of ethylenethioureas and process
NL131034C (en) *	1964-05-11
US3297708A (en) *	1965-10-06	1967-01-10	American Cyanamid Co	Method of preparing thiazolidines
US3455924A (en) *	1967-02-08	1969-07-15	Upjohn Co	Dianisylimidazoles
NL164285C (en) *	1968-01-09	1980-12-15	Rhone Poulenc Sa	PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION CONTAINING AN IMIDAZOŸ2.1-BŸTHIAZOLE DERIVATIVE, THE PREPARED PHARMACEUTICAL PREPARATIONS AND A METHOD FOR PREPARING THIS IMIDAZOŸ2.1-BŸTHIAZOLDER
BE788792A (en) *	1971-09-30	1973-03-13	Ici Ltd	METHODS AND COMPOSITIONS FOR ANTI-BACTERIAL USE
US3842097A (en) *	1973-01-22	1974-10-15	Searle & Co	2-(phenoxyalkylthio)imidazoles and congeners
SE428686B (en) *	1975-08-11	1983-07-18	Du Pont	PROCEDURE FOR PREPARING ANTI-INFLAMMATORALLY ACTIVE IMIDAZOLS
GB1541321A (en) *	1976-03-10	1979-02-28	Metabio	2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
US4064260A (en) *	1976-07-29	1977-12-20	E. I. Du Pont De Nemours And Company	Anti-inflammatory diarylimidazothiazoles and their corresponding S-oxides
US4263311A (en) *	1976-09-27	1981-04-21	Smithkline Corporation	5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles

1977
- 1977-07-07 LU LU77703A patent/LU77703A1/en unknown
1978
- 1978-06-29 EP EP80101322A patent/EP0020858A1/en not_active Withdrawn
- 1978-06-29 EP EP80101323A patent/EP0019688A1/en not_active Ceased
- 1978-06-29 EP EP78100272A patent/EP0000353A3/en not_active Withdrawn
- 1978-07-03 FI FI782132A patent/FI782132A/en not_active Application Discontinuation
- 1978-07-03 PT PT68246A patent/PT68246A/en unknown
- 1978-07-05 AR AR272843A patent/AR222309A1/en active
- 1978-07-05 AU AU37788/78A patent/AU3778878A/en active Pending
- 1978-07-05 GR GR56695A patent/GR64978B/en unknown
- 1978-07-05 IL IL55086A patent/IL55086A0/en unknown
- 1978-07-05 ES ES471458A patent/ES471458A1/en not_active Expired
- 1978-07-06 DD DD78206565A patent/DD138212A5/en unknown
- 1978-07-06 JP JP8153378A patent/JPS5416470A/en active Pending
- 1978-07-06 NZ NZ187789A patent/NZ187789A/en unknown
- 1978-07-06 SU SU782632647A patent/SU873886A3/en active
- 1978-07-06 DD DD78214990A patent/DD145538A5/en unknown
- 1978-07-06 ZA ZA00783898A patent/ZA783898B/en unknown
- 1978-07-06 NO NO782357A patent/NO782357L/en unknown
- 1978-07-06 DK DK783055A patent/DK305578A/en unknown
- 1978-07-07 PL PL1978208253A patent/PL116596B1/en unknown
1979
- 1979-03-05 ES ES478296A patent/ES478296A1/en not_active Expired
- 1979-05-18 SU SU792763599A patent/SU893134A3/en active
- 1979-09-10 ES ES484033A patent/ES484033A1/en not_active Expired
- 1979-09-20 ES ES484327A patent/ES484327A1/en not_active Expired
- 1979-10-23 SU SU792831085A patent/SU850007A3/en active
- 1979-12-03 AR AR279136A patent/AR224381A1/en active
- 1979-12-20 SU SU792855458A patent/SU873887A3/en active
1981
- 1981-11-06 IT IT8149647A patent/IT8149647A0/en unknown

Also Published As

Publication number	Publication date
PT68246A (en)	1978-08-01
FI782132A (en)	1979-01-08
LU77703A1 (en)	1979-03-26
AR222309A1 (en)	1981-05-15
IL55086A0 (en)	1978-09-29
ES484327A1 (en)	1980-05-16
SU873886A3 (en)	1981-10-15
NZ187789A (en)	1981-03-16
SU893134A3 (en)	1981-12-23
ES484033A1 (en)	1980-04-16
ES478296A1 (en)	1979-05-16
SU873887A3 (en)	1981-10-15
EP0000353A3 (en)	1979-06-13
ES471458A1 (en)	1979-10-01
SU850007A3 (en)	1981-07-23
GR64978B (en)	1980-06-11
AU3778878A (en)	1980-01-10
NO782357L (en)	1979-01-09
JPS5416470A (en)	1979-02-07
DK305578A (en)	1979-01-08
PL208253A1 (en)	1979-06-04
EP0019688A1 (en)	1980-12-10
PL116596B1 (en)	1981-06-30
EP0020858A1 (en)	1981-01-07
AR224381A1 (en)	1981-11-30
DD145538A5 (en)	1980-12-17
DD138212A5 (en)	1979-10-17
EP0000353A2 (en)	1979-01-24
IT8149647A0 (en)	1981-11-06

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