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AR211097A1 - Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida. - Google Patents

Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida.

Info

Publication number
AR211097A1
AR211097A1 AR258409A AR25840975A AR211097A1 AR 211097 A1 AR211097 A1 AR 211097A1 AR 258409 A AR258409 A AR 258409A AR 25840975 A AR25840975 A AR 25840975A AR 211097 A1 AR211097 A1 AR 211097A1
Authority
AR
Argentina
Prior art keywords
carbamil
pyridina
sulfamido
thiocarbamyl
substituted
Prior art date
Application number
AR258409A
Other languages
English (en)
Original Assignee
Christiaens Sa A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christiaens Sa A filed Critical Christiaens Sa A
Application granted granted Critical
Publication of AR211097A1 publication Critical patent/AR211097A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AR258409A 1974-04-17 1975-04-17 Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida. AR211097A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1683674A GB1477664A (en) 1974-04-17 1974-04-17 Pyridine derivatives
YU1507/81A YU42409B (en) 1974-04-17 1981-06-15 Process for obtaining new pyridine derivatives

Publications (1)

Publication Number Publication Date
AR211097A1 true AR211097A1 (es) 1977-10-31

Family

ID=26252269

Family Applications (4)

Application Number Title Priority Date Filing Date
AR258409A AR211097A1 (es) 1974-04-17 1975-04-17 Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida.
AR262626A AR208769A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 3-sulfonamido-piridina
AR262627A AR208770A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 3(acilsulfonamido)-piridina-4-sustituida
AR262625A AR208768A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 4-amino-3-sulfonamido-piridina

Family Applications After (3)

Application Number Title Priority Date Filing Date
AR262626A AR208769A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 3-sulfonamido-piridina
AR262627A AR208770A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 3(acilsulfonamido)-piridina-4-sustituida
AR262625A AR208768A1 (es) 1974-04-17 1976-03-19 Un procedimiento para preparar nuevos derivados de la 4-amino-3-sulfonamido-piridina

Country Status (19)

Country Link
US (2) US4018929A (es)
JP (1) JPS5951536B2 (es)
AR (4) AR211097A1 (es)
AT (1) AT344170B (es)
BE (1) BE827844A (es)
CA (1) CA1070313A (es)
CH (3) CH609045A5 (es)
DD (2) DD126887A5 (es)
DE (1) DE2516025A1 (es)
ES (4) ES436581A1 (es)
FR (1) FR2267775B1 (es)
GB (1) GB1477664A (es)
HU (1) HU171420B (es)
IL (1) IL47084A (es)
LU (2) LU72284A1 (es)
NL (2) NL183580C (es)
SE (2) SE424320B (es)
YU (1) YU42409B (es)
ZA (1) ZA752243B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
US4776878A (en) * 1978-12-04 1988-10-11 E. I. Du Pont De Nemours And Company Agricultural pyridinesulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
US4853389A (en) * 1987-07-24 1989-08-01 American Home Products Corporation Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas
US4914203A (en) * 1987-07-24 1990-04-03 American Home Products Corporation 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas
FR2659080B1 (fr) * 1990-03-02 1994-07-08 Adir Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
US5486530A (en) * 1991-04-27 1996-01-23 Boehringer Mannheim Gmbh Use of torasemide for the treatment of brain oedemas
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
HRP980532B1 (en) * 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) * 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
AU781461C (en) * 1999-08-11 2006-02-23 Teva Pharmaceutical Industries Ltd. Torsemide polymorphs
IL157539A0 (en) * 2000-02-17 2004-03-28 Teva Pharma A stable pharmaceutical formulation comprising torsemide modification ii
HRP20000162B1 (en) * 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
EP1741429A3 (en) * 2000-03-20 2007-01-17 Teva Pharmaceutical Industries Ltd. Processes for preparing torsemide
AU4759201A (en) 2000-03-20 2001-10-03 Teva Pharma Novel processes for preparing torsemide intermediate
HRP20000328A2 (en) * 2000-05-19 2002-02-28 Pliva Farmaceutska Ind Dionik Novel polymorph v of torasemide
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (es) 2001-08-03 2004-03-06 Ranbaxy Lab
IL149771A0 (en) * 2002-05-21 2002-11-10 Fintech Lab Ltd Process for preparation of torsemide
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
CA2495962A1 (en) 2002-08-19 2004-03-04 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
CA2401546C (en) * 2002-09-06 2006-09-19 Brantford Chemicals Inc. Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine
ITMI20022749A1 (it) * 2002-12-23 2004-06-24 Cosma S P A Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20050215600A1 (en) * 2003-10-27 2005-09-29 Arie Gutman Polymorphs of torsemide hydrochloride and process for production thereof
US7378527B2 (en) * 2004-03-16 2008-05-27 Daqing Che Process for the preparation of torsemide and related intermediates
JP2009511629A (ja) * 2005-10-17 2009-03-19 ニューロセラピューティクス ファーマ， インコーポレイテッド 中枢神経系疾患の調節に有用な利尿薬様化合物類似体
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US7939532B2 (en) * 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN101675033A (zh) * 2007-05-16 2010-03-17 霍夫曼-拉罗奇有限公司 芳基吡啶基磺酰胺衍生物，它们的制备和作为药剂的应用
NL2006622C2 (en) 2011-04-18 2012-10-22 Eurovet Animal Health B V Use of a composition comprising torasemide.
US9616075B2 (en) 2012-07-20 2017-04-11 University Of Rochester Method of treating and preventing brain impairment using Na+-K+-2Cl-cotransporter isoform 1 inhibitors
BR112015026513A2 (pt) 2013-04-17 2017-07-25 Pfizer derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
AU2016222278B2 (en) 2015-02-16 2020-07-09 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Sulfonylureas and related compounds and use of same
IL271716B2 (en) 2017-07-07 2024-09-01 Inflazome Ltd Sulfonamide Carboxamide Compounds as NLRP3 Inhibitors, Pharmaceutical Preparations and Their Uses
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine

Also Published As

Publication number Publication date
LU72284A1 (es) 1975-08-20
NL183580C (nl) 1988-12-01
DD121936A5 (es) 1976-09-05
AU8001675A (en) 1976-10-14
DE2516025C2 (es) 1988-11-03
FR2267775B1 (es) 1978-11-10
YU42409B (en) 1988-08-31
BE827844A (fr) 1975-10-13
US4018929A (en) 1977-04-19
NL7504521A (nl) 1975-10-21
CH609045A5 (es) 1979-02-15
ES453327A1 (es) 1977-11-16
AR208768A1 (es) 1977-02-28
ES453329A1 (es) 1977-11-16
CH612424A5 (es) 1979-07-31
AR208770A1 (es) 1977-02-28
CA1070313A (en) 1980-01-22
YU150781A (en) 1984-02-29
IL47084A (en) 1979-01-31
ES436581A1 (es) 1977-04-01
ATA288275A (de) 1977-11-15
ES453328A1 (es) 1977-11-01
JPS50142571A (es) 1975-11-17
SE7907618L (sv) 1979-09-13
DE2516025A1 (de) 1975-11-06
IL47084A0 (en) 1975-06-25
SE7504409L (sv) 1975-10-20
AT344170B (de) 1978-07-10
USRE30633E (en) 1981-06-02
NL940014I1 (nl) 1994-09-16
DD126887A5 (es) 1977-08-17
FR2267775A1 (es) 1975-11-14
LU88346I2 (fr) 1994-05-04
JPS5951536B2 (ja) 1984-12-14
GB1477664A (en) 1977-06-22
SE424320B (sv) 1982-07-12
CH610890A5 (es) 1979-05-15
ZA752243B (en) 1976-03-31
NL183580B (nl) 1988-07-01
HU171420B (hu) 1978-01-28
AR208769A1 (es) 1977-02-28
NL940014I2 (nl) 1997-04-01

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