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AR215930A1 - Procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno - Google Patents

Procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno

Info

Publication number
AR215930A1
AR215930A1 AR272154A AR27215478A AR215930A1 AR 215930 A1 AR215930 A1 AR 215930A1 AR 272154 A AR272154 A AR 272154A AR 27215478 A AR27215478 A AR 27215478A AR 215930 A1 AR215930 A1 AR 215930A1
Authority
AR
Argentina
Prior art keywords
benzothiophene
benzoyl
phenyl
compounds
procedure
Prior art date
Application number
AR272154A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR215930A1 publication Critical patent/AR215930A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AR272154A 1975-10-28 1978-05-12 Procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno AR215930A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62601075A 1975-10-28 1975-10-28

Publications (1)

Publication Number Publication Date
AR215930A1 true AR215930A1 (es) 1979-11-15

Family

ID=24508581

Family Applications (3)

Application Number Title Priority Date Filing Date
AR265277A AR222959A1 (es) 1975-10-28 1976-10-28 Un procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno,los 6-hidroxi o 6-alcoxi(c1-c5)derivados de los mismos y los correspondientes 1-oxidos
AR272154A AR215930A1 (es) 1975-10-28 1978-05-12 Procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno
AR272153A AR222796A1 (es) 1975-10-28 1978-05-12 Un procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AR265277A AR222959A1 (es) 1975-10-28 1976-10-28 Un procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno,los 6-hidroxi o 6-alcoxi(c1-c5)derivados de los mismos y los correspondientes 1-oxidos

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR272153A AR222796A1 (es) 1975-10-28 1978-05-12 Un procedimiento para la preparacion de compuestos 2-fenil-3-benzoil-benzotiofeno

Country Status (31)

Country Link
US (1) US4133814A (es)
JP (1) JPS5253851A (es)
AR (3) AR222959A1 (es)
AT (1) AT357520B (es)
AU (1) AU505360B2 (es)
BE (1) BE847719A (es)
BG (2) BG28065A4 (es)
CA (1) CA1090795A (es)
CH (3) CH635336A5 (es)
CS (2) CS205047B2 (es)
DD (1) DD127461A5 (es)
DE (1) DE2647907C2 (es)
DK (1) DK152045C (es)
ES (2) ES452694A1 (es)
FR (1) FR2329271A1 (es)
GB (1) GB1570610A (es)
GR (1) GR61776B (es)
HU (1) HU179012B (es)
IE (1) IE44392B1 (es)
IL (1) IL50773A (es)
MX (1) MX4584E (es)
NL (1) NL7611975A (es)
NZ (1) NZ182429A (es)
PH (1) PH14219A (es)
PL (2) PL114190B1 (es)
PT (1) PT65755B (es)
RO (1) RO70769A (es)
SE (1) SE426945B (es)
SU (2) SU701539A3 (es)
YU (1) YU262076A (es)
ZA (1) ZA766440B (es)

Families Citing this family (301)

* Cited by examiner, † Cited by third party
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US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5391557A (en) * 1993-10-15 1995-02-21 Eli Lilly And Company Methods for the treatment of peri-menopausal syndrome
UA32427C2 (uk) * 1993-10-15 2000-12-15 Елі Ліллі Енд Компані Застосування бензотіофенів або їх фармацевтично прийнятних солей або сольватів для інгібування ангіогенезу і/або ангіогенних захворювань
US5457113A (en) * 1993-10-15 1995-10-10 Eli Lilly And Company Methods for inhibiting vascular smooth muscle cell proliferation and restinosis
US5457116A (en) * 1993-10-15 1995-10-10 Eli Lilly And Company Methods of inhibiting uterine fibrosis
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US5441964A (en) * 1993-10-15 1995-08-15 Eli Lilly And Company Methods for inhibiting bone loss using substituted benzothiophene
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DE2647907A1 (de) 1977-05-12
US4133814A (en) 1979-01-09
NZ182429A (en) 1978-11-13
NL7611975A (nl) 1977-05-02
CH635582A5 (de) 1983-04-15
FR2329271A1 (fr) 1977-05-27
PT65755B (en) 1978-04-27
HU179012B (en) 1982-08-28
BE847719A (fr) 1977-04-28
ES452694A1 (es) 1977-11-16
PH14219A (en) 1981-04-02
DK484876A (da) 1977-04-29
YU262076A (en) 1983-01-21
SU764610A3 (ru) 1980-09-15
PL193308A1 (pl) 1978-03-28
PL107979B1 (pl) 1980-03-31
AU1900576A (en) 1978-05-04
DK152045B (da) 1988-01-25
DK152045C (da) 1988-06-20
ES452695A1 (es) 1977-11-16
IE44392B1 (en) 1981-11-18
SE7611955L (sv) 1977-04-29
DE2647907C2 (de) 1985-01-24
AR222796A1 (es) 1981-06-30
AT357520B (de) 1980-07-10
GB1570610A (en) 1980-07-02
ZA766440B (en) 1978-06-28
RO70769A (ro) 1982-10-26
JPS5253851A (en) 1977-04-30
ATA800876A (de) 1979-12-15
CH634316A5 (de) 1983-01-31
BG28065A4 (en) 1980-02-25
MX4584E (es) 1982-06-25
SU701539A3 (ru) 1979-11-30
AR222959A1 (es) 1981-07-15
SE426945B (sv) 1983-02-21
IL50773A (en) 1980-03-31
FR2329271B1 (es) 1979-07-27
CS205046B2 (en) 1981-04-30
JPS61343B2 (es) 1986-01-08
DD127461A5 (es) 1977-09-28

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