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AR074166A1 - Procedimiento para la preparacion de aminobifenilos y compuestos derivados de los mismos - Google Patents

Procedimiento para la preparacion de aminobifenilos y compuestos derivados de los mismos

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Publication number
AR074166A1
AR074166A1 ARP090102516A ARP090102516A AR074166A1 AR 074166 A1 AR074166 A1 AR 074166A1 AR P090102516 A ARP090102516 A AR P090102516A AR P090102516 A ARP090102516 A AR P090102516A AR 074166 A1 AR074166 A1 AR 074166A1
Authority
AR
Argentina
Prior art keywords
alkyl
haloalkyl
aryl
haloalkoxy
alkoxy
Prior art date
Application number
ARP090102516A
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English (en)
Original Assignee
Univ Muenchen Tech
Basf Se
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Filing date
Publication date
Application filed by Univ Muenchen Tech, Basf Se filed Critical Univ Muenchen Tech
Publication of AR074166A1 publication Critical patent/AR074166A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/80Preparation of compounds containing amino groups bound to a carbon skeleton by photochemical reactions; by using free radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/75Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

Un procedimiento para la preparacion de aminobifenilos sustituidos, en particular 2-aminobifenilos así como un procedimiento para la preparacion de amidas de ácidos (hetero)acrílicos de tales aminobifenilos en particular 2-aminobifenilos, en donde dicho procedimiento para la preparacion de aminobifenilos de formula (1), en la que m representa 0, 1, 2 o 3; cada R1, respectivamente de forma independiente, representa halogeno, alquilo C1-4, haloalquilo C1-4, hidroxialquilo C1-4, alquenilo C2-4, alquinilo C2-4. cicloalquilo C3-6, alcoxi C1-4, haloalcoxi C1-4, alquil C1-4-tio, haloalquil C1-4-tio, nitro, ciano SO3R3, SO2R3, SO2NR10R11, COOR2, COR4, OCOR4, CONR10R11, NR10COR4, R10SO2R3, alquil C1-4-imino, arilo, ariloxi, arilcarbonilo, arilalquilo C1-4, arilmetoxicarbonilo, arilalquilimino o hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo, en donde el grupo arilo y el grupo hetarilo en los ultimos 7 radicales mencionados lleva eventualmente 1, 2, 3, 4 o 5 sustituyentes, que están seleccionados de entre halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; A representa hidrogeno, NR5R6, (NR7R8R9)+V-, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4, haloalcoxi C1-4, alquil C1-4-carbonilo, haloalquil C1-4-carbonilo, nitro, hidroxilo, SO3R3, COOR2, CONR10R11, COR4, arilo o ariloxi, portando el grupo arilo en los dos radicales nombrados en ultimo término, dado el caso 1, 2, 3 o 4 sustituyentes, que están seleccionados de entre halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; y E representa hidrogeno, halogeno, alquilo C1-4, haloalquilo C1-4, hidroxialquilo C1-4, cicloalquilo C3-6, arilo o hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo, en donde el grupo arilo y el grupo hetarilo llevan eventualmente 1, 2, 3, 4 o 5 sustituyentes, que están seleccionados de halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; en los que cada R2 representa en cada caso, de modo independiente, hidrogeno, alquilo C1-4, haloalquilo C1-4, hidroxialquilo C1-4, alquenilo C2-4, alquinilo C2-4, cicloalquilo C3-6, arilo, hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo o un equivalente cationico; R3 representa hidrogeno, alquilo C1-4, haloalquilo C1-4, hidroxialquilo C1-4, alquenilo C2-4, alquinilo C2-4, cicloalquilo C3-6, arilo, hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo; R4 representa hidrogeno, alquilo C1-4, haloalquilo C1-4, hidroxialquilo C1-4, alquenilo C2-4, alquinilo C2-4, cicloalquilo C3-6, arilo, hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo; R5 y R6, independientemente el uno del otro, representan hidrogeno, alquilo C1-10, alquenilo C3-4, cicloalquilo C3-10, alquil C1-4-carbonilo, haloalquil C1-4-carbonilo, alquenil C3-4-carbonilo, alcoxi C1-4-carbonilo, haloalcoxi C1-4-carbonilo, alqueniloxi C3-4-carbonilo, alquil C1-4-aminocarbonilo, di-(alquilo C1-4)-aminocarbonilo, alquil C1-4-sulfonilo, haloalquil-C1-4-sulfonilo, arilo, arilalquilo C1-4, arilcarbonilo, ariloxicarbonilo o arilmetoxicarbonilo, portando los grupos arilo de los cinco sustituyentes nombrados en ultimo término, dado el caso, respectivamente 1, 2, 3 o 4 sustituyentes que están seleccionados de entre halogeno, nitro, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; o R5 y R6 juntos forman un grupo =CR12-NR13R14 o juntos con el átomo de nitrogeno al que están unidos forman un grupo alquil C1-4-imino o un grupo arilalquil C1-4-imino; R7, R8 y R9, independientemente unos de otros, representan alquilo C1-10; R10 y R11, en cada caso, independientemente, representan hidrogeno, alquilo C1-10, haloalquilo C1-10, hidroxialquilo C1-10, alquenilo C2-4, alquinilo C2-4, cicloalquilo C3-10, alquil C1-4-carbonilo, haloalquil C1-4-carbonilo, alquenil C3-4-carbonilo, alcoxi C1-4-carbonilo, haloalcoxi C1-4-carbonilo, alqueniloxi C3-4-carbonilo, alquil C1-4-sulfonilo, haloalquil C1-4-sulfonilo, arilo, arilalquilo C1-4, arilcarbonilo, ariloxicarbonilo, arilmetoxicarbonilo o hetarilo de 5 o 6 miembros con 1, 2 o 3 heteroátomos, que están seleccionados de N, O y S, como miembros del anillo, portando los grupos arilo y hetarilo de los 6 sustituyentes nombrados en ultimo término, dado el caso, respectivamente 1, 2, 3 o 4 sustituyentes, que están seleccionados de entre halogeno, nitro, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; R12, R13 y R14, independientemente unos de otros, representan hidrogeno, alquilo C1-10 o arilo; y V- denomina un anion monovalente o una parte equivalente a un anion monovalente de un anion polivalente; comprende los siguientes pasos: (i) reaccion de una sal de diazonio de formula (2) con un derivado de anilina de formula (3), en las que A' posee uno de los significados indicados para A, con la condicion de que A' no represente hidrogeno; X- denomina un anion monovalente o una parte equivalente a un anion monovalente de un anion polivalente, y m, E y R1 tienen los significados nombrados anteriormente, en condiciones de reaccion que pueden generar una descomposicion de la sal de diazonio de formula (2) en nitrogeno y un radical arilo, obteniéndose un aminobifenilo de formula (4), y (ii) dado el caso, transformacion del aminobifenilo de formula (4) obtenido en el paso (i) en un aminobifenilo de formula (1), en la que A representa hidrogeno. Reivindicacion 40: Compuestos caracterizados porque tienen la formula (5), en la que: A representa nitro, R1a representa H, R1b representa Cl y R1c representa H; A representa Cl, R1a representa H, R1b representa Cl y R1c representa H; A representa Br, R1a representa H, R1b representa Cl y R1c representa H; A representa NH2, R1a representa H, R1b representa Cl y R1c representa Cl; A representa Br, R1a representa H, R1b representa Cl y R1c representa Cl; A representa NH2, R1a representa F, R1b representa F y R1c representa F; A representa nitro, R1a representa F, R1b representa F y R1c representa F; A representa Cl, R1a representa F, R1b representa F y R1c representa F; A representa Br, R1a representa F, R1b representa F y R1c representa F; A representa F, R1a representa F, R1b representa F y R1c representa F.
ARP090102516A 2008-07-03 2009-07-03 Procedimiento para la preparacion de aminobifenilos y compuestos derivados de los mismos AR074166A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08159632 2008-07-03
EP08166713 2008-10-15

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AR074166A1 true AR074166A1 (es) 2010-12-29

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US (1) US8637707B2 (es)
EP (1) EP2310353A1 (es)
JP (1) JP2011526604A (es)
KR (1) KR20110027834A (es)
CN (1) CN102143935B (es)
AR (1) AR074166A1 (es)
BR (1) BRPI0914924A2 (es)
CA (1) CA2728223A1 (es)
IL (1) IL210051A0 (es)
MX (1) MX2010014132A (es)
WO (1) WO2010000856A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8492558B2 (en) 2009-02-19 2013-07-23 Basf Se Method for producing 2-aminobiphenylene
CN103517893A (zh) * 2011-03-07 2014-01-15 巴斯夫欧洲公司 合成氨基联苯的方法
EP2546229A1 (de) 2011-07-15 2013-01-16 Friedrich-Alexander-Universität Erlangen-Nürnberg Verfahren zur Synthese von Aminobiphenylen
EP2822924B1 (de) * 2012-03-07 2019-12-04 Basf Se Verfahren zur synthese von aminobiphenylen unter verwendung von arylhydrazinen
CN103603007B (zh) * 2013-11-12 2015-12-02 北京工业大学 2-n-取代苯并噁唑类化合物的电化学催化合成方法
CN115261896B (zh) * 2022-08-16 2024-08-30 深圳职业技术学院 一种4’-烷胺基苯甲基-3-咪唑并[1,2-a]吡啶类衍生物的合成方法
CN118048636B (zh) * 2024-03-12 2024-09-13 平顶山学院 一种n-芳基酰胺电催化合成方法

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US8492558B2 (en) 2009-02-19 2013-07-23 Basf Se Method for producing 2-aminobiphenylene

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MX2010014132A (es) 2011-07-28
CA2728223A1 (en) 2010-01-07
KR20110027834A (ko) 2011-03-16
EP2310353A1 (de) 2011-04-20
BRPI0914924A2 (pt) 2015-10-20
US8637707B2 (en) 2014-01-28
CN102143935B (zh) 2014-10-22
US20110105760A1 (en) 2011-05-05
IL210051A0 (en) 2011-02-28
WO2010000856A1 (de) 2010-01-07
CN102143935A (zh) 2011-08-03
JP2011526604A (ja) 2011-10-13

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