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AR064012A2 - Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol el uso de dichas composiciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares diabetes obesidad o reduccion de - Google Patents

Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol el uso de dichas composiciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares diabetes obesidad o reduccion de

Info

Publication number
AR064012A2
AR064012A2 ARP070105283A ARP070105283A AR064012A2 AR 064012 A2 AR064012 A2 AR 064012A2 AR P070105283 A ARP070105283 A AR P070105283A AR P070105283 A ARP070105283 A AR P070105283A AR 064012 A2 AR064012 A2 AR 064012A2
Authority
AR
Argentina
Prior art keywords
compositions
objective
combinations
manufacture
absorption inhibitor
Prior art date
Application number
ARP070105283A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26950511&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR064012(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR064012A2 publication Critical patent/AR064012A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/055—Phenols the aromatic ring being substituted by halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proveen composiciones y combinaciones terapéuticas que incluyen: (a) al menos un activador del receptor de activacion de proliferacion peroxisomal; y (b) al menos un inhibidor de absorcion de esterol de beta-lactama sustituido o azetidinona sustituida. Una composicion que comprende: (a) un compuesto representado por la formula (2) o una sal o solvato farmacéuticamente aceptable del mismo; (b) monohidrato de lactosa; (c) celulosa microcristalina; (d) povidona; (e) croscarmelosa sádica; (f) lauril sulfato sodico; y (g) estearato de magnesio, con la condicion de que la composicion no comprende: Ingrediente Porcentual en Peso de Ingrediente Compuesto de formula (2) 10 Monohidrato de lactosa 55 Celulosa microcristalina 20 Povidona 4 Croscarmelosa sádica 8 Lauril sulfato sodico 2 Estearato de magnesio 1 Total 100 También se describe el uso de dichas composiciones y combinaciones para la manufactura de un medicamento utiles para el tratamiento de enfermedades vasculares, diabetes, obesidad y reduccion de los niveles de plasma de esteroles.
ARP070105283A 2001-01-26 2007-11-28 Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol el uso de dichas composiciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares diabetes obesidad o reduccion de AR064012A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26439601P 2001-01-26 2001-01-26
US32383901P 2001-09-21 2001-09-21

Publications (1)

Publication Number Publication Date
AR064012A2 true AR064012A2 (es) 2009-03-04

Family

ID=26950511

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP020100269A AR033855A1 (es) 2001-01-26 2002-01-25 Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxis0mal (ppar) e inhibidor(es) de absorcion de esterol, el uso de dichas composiciones o combinaciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares, diabetes, obes
ARP070105283A AR064012A2 (es) 2001-01-26 2007-11-28 Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol el uso de dichas composiciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares diabetes obesidad o reduccion de

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP020100269A AR033855A1 (es) 2001-01-26 2002-01-25 Composiciones y combinaciones de activador(es) del receptor de activacion de proliferacion peroxis0mal (ppar) e inhibidor(es) de absorcion de esterol, el uso de dichas composiciones o combinaciones para la manufactura de un medicamento para el tratamiento para indicaciones vasculares, diabetes, obes

Country Status (33)

Country Link
US (5) US20020151536A1 (es)
EP (2) EP1353696B1 (es)
JP (4) JP4777602B2 (es)
KR (1) KR100596257B1 (es)
CN (1) CN100509058C (es)
AR (2) AR033855A1 (es)
AT (2) ATE374641T1 (es)
AU (1) AU2002247019C1 (es)
BR (1) BR0206654A (es)
CA (3) CA2563051A1 (es)
CL (1) CL2004001174A1 (es)
CY (2) CY1108000T1 (es)
CZ (2) CZ301871B6 (es)
DE (2) DE60222773T2 (es)
DK (2) DK1413331T3 (es)
EC (1) ECSP11004702A (es)
ES (2) ES2290562T3 (es)
HK (2) HK1063607A1 (es)
HU (2) HUP0303915A3 (es)
IL (3) IL156445A0 (es)
ME (1) MEP27808A (es)
MX (1) MXPA03006725A (es)
NO (1) NO331512B1 (es)
NZ (1) NZ525921A (es)
PL (1) PL208110B1 (es)
PT (2) PT1413331E (es)
RS (2) RS20100015A (es)
RU (1) RU2356550C2 (es)
SI (2) SI1413331T1 (es)
SK (2) SK287988B6 (es)
TW (1) TWI337083B (es)
WO (1) WO2002058732A2 (es)
ZA (1) ZA200305693B (es)

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