[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

AR059376A1 - Procedimiento para la produccion de acidos grasos poliinsaturados - Google Patents

Procedimiento para la produccion de acidos grasos poliinsaturados

Info

Publication number
AR059376A1
AR059376A1 ARP070100533A ARP070100533A AR059376A1 AR 059376 A1 AR059376 A1 AR 059376A1 AR P070100533 A ARP070100533 A AR P070100533A AR P070100533 A ARP070100533 A AR P070100533A AR 059376 A1 AR059376 A1 AR 059376A1
Authority
AR
Argentina
Prior art keywords
nucleic acid
polypeptide
acid sequence
sequence encoding
production
Prior art date
Application number
ARP070100533A
Other languages
English (en)
Inventor
Bifang Cheng
Martin Truksa
Tom Wetjen
Petra Cirpus
Jorg Bauer
Xiao Qiu
Guohai Wu
Original Assignee
Basf Plant Science Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38137303&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR059376(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102006008030A external-priority patent/DE102006008030A1/de
Application filed by Basf Plant Science Gmbh filed Critical Basf Plant Science Gmbh
Publication of AR059376A1 publication Critical patent/AR059376A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fats And Perfumes (AREA)

Abstract

La presente se refiere a un procedimiento para la produccion de ácido eicosapentaenoico, ácido docosapentaenoico y/o ácido docosahexaenoico en plantas transgénicas, por medio del cual se proveen en la planta por lo menos una secuencia de ácidos nucleicos que codifica para un polipéptido con una actividad delta6-desaturasa; por lo menos una secuencia de ácidos nucleicos que codifica para un polipéptido con una actividad delta6-elongasa; por lo menos una secuencia de ácidos nucleicos que codifica para un polipéptido con una actividad delta5-desaturasa; y por lo menos una secuencia de ácidos nucleicos que codifica para un polipéptido con una actividad delta5-elongasa, en donde la secuencia de ácidos nucleicos que codifica para un polipéptido con una actividad delta5-elongasa, está modificada con respecto a la secuencia de ácidos nucleicos en el organismo del cual procede la secuencia de tal manera que está adaptada al uso del codon en una o más especies de plantas. Para la produccion de ácido docosahexaenoico se introducen en la planta una o más secuencias de ácidos nucleicos, que codifican para un polipéptido con una actividad delta4-desaturasa.
ARP070100533A 2006-02-21 2007-02-08 Procedimiento para la produccion de acidos grasos poliinsaturados AR059376A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006008030A DE102006008030A1 (de) 2006-02-21 2006-02-21 Verfahren zur Herstellung von mehrfach ungesättigten Fettsäuren
EP06120309 2006-09-07

Publications (1)

Publication Number Publication Date
AR059376A1 true AR059376A1 (es) 2008-03-26

Family

ID=38137303

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070100533A AR059376A1 (es) 2006-02-21 2007-02-08 Procedimiento para la produccion de acidos grasos poliinsaturados

Country Status (7)

Country Link
US (7) US10190131B2 (es)
EP (1) EP1991684B1 (es)
AR (1) AR059376A1 (es)
AU (2) AU2007217554A1 (es)
BR (1) BRPI0708082A2 (es)
CA (2) CA2642929C (es)
WO (1) WO2007096387A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
PT2166069T (pt) 2003-08-01 2016-09-13 Basf Plant Science Gmbh Método de produção de ácidos gordos polinsaturados em organismos transgénicos
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
ES2715640T3 (es) 2004-04-22 2019-06-05 Commw Scient Ind Res Org Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
AU2013202498B2 (en) * 2006-08-24 2015-04-30 Basf Plant Science Gmbh Isolation and characterization of a novel Pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
EP2059588A4 (en) 2006-08-29 2010-07-28 Commw Scient Ind Res Org FATTY ACID SYNTHESIS
US8119784B2 (en) 2008-04-02 2012-02-21 E. I. Du Pont De Nemours And Company Delta-4 desaturase and its use in making polyunsaturated fatty acids
DE112009002048T5 (de) * 2008-08-26 2012-01-26 Basf Plant Science Gmbh Nukleinsäure, die Desaturasen kodieren, und modifiziertes Planzenöl
AU2013204254B8 (en) * 2008-11-18 2015-10-08 Commonwealth Scientific And Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
AU2015224521B2 (en) * 2008-11-18 2017-09-14 Commonwealth Scientific And Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
JP6068800B2 (ja) * 2008-11-18 2017-01-25 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション オメガ−３脂肪酸を産生するための酵素および方法
PL2376638T3 (pl) * 2008-12-12 2014-01-31 Basf Plant Science Gmbh Desaturazy oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych w organizmach transgenicznych
CA3037072C (en) * 2009-07-17 2022-07-26 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
DK2496091T3 (da) * 2009-11-03 2019-11-04 Dsm Ip Assets Bv Vegetabilsk olie, der omfatter en flerumættet fedtsyre med mindst 20 carbonatomer
EP2800563B1 (en) 2012-01-06 2018-07-11 Omthera Pharmaceuticals Inc. Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
EP2846779A4 (en) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
CN104853596B (zh) 2012-06-15 2018-10-09 联邦科学技术研究组织 在植物细胞中产生长链多不饱和脂肪酸
DK2970926T3 (en) 2013-03-13 2018-04-16 Dsm Nutritional Products Ag GENMANIPULATION OF MICROorganisms
AU2014285720B2 (en) 2013-07-05 2020-10-15 Basf Plant Science Company Gmbh Gene expression or activity enhancing elements
US11718577B2 (en) 2013-12-18 2023-08-08 Commonwealth Scientific And Industrial Research Organisation Lipid compositions comprising triacylglycerol with long-chain polyunsaturated fatty acids
KR102386838B1 (ko) 2013-12-18 2022-04-15 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 장쇄 다중불포화 지방산을 포함하는 지질
CN105219789B (zh) 2014-06-27 2023-04-07 联邦科学技术研究组织 包含二十二碳五烯酸的提取的植物脂质
EA037184B1 (ru) * 2014-06-27 2021-02-16 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Липид, содержащий докозапентаеновую кислоту
SG10201909391QA (en) * 2014-06-27 2019-11-28 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
AU2015345049B2 (en) 2014-11-14 2021-12-23 Basf Plant Science Company Gmbh Brassica events LBFLFK and LBFDAU and methods for detection thereof
AR109245A1 (es) * 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
CA3129494A1 (en) 2019-02-14 2020-08-20 Cargill, Incorporated Brassica plants producing elevated levels of polyunsaturated fatty acids
EP4240144A1 (en) 2020-11-04 2023-09-13 BASF Plant Science Company GmbH Harvest management
CN117042596A (zh) 2021-03-25 2023-11-10 巴斯夫植物科学有限公司 肥料管理

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077896C (en) 1990-03-16 2008-02-19 Gregory A. Thompson Plant desaturases - compositions and uses
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
DK0616644T3 (da) 1991-12-04 2003-10-27 Du Pont Fedtsyredesaturase-gener fra planter
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
JP3818540B2 (ja) 1992-11-17 2006-09-06 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 植物由来のミクロソームデルタ−１２脂肪酸デサチュラーゼおよび関連酵素の遺伝子
WO1994018337A1 (en) 1993-02-05 1994-08-18 Monsanto Company Altered linolenic and linoleic acid content in plants
EP0736598B1 (en) 1993-12-28 2004-08-11 Kirin Beer Kabushiki Kaisha Gene for fatty acid desaturase, vector containing said gene, plant containing said gene transferred thereinto, and process for creating said plant
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
AU1293297A (en) 1995-12-14 1997-07-03 Cargill Incorporated Plants having mutant sequences that confer altered fatty acid profiles
EP0794250A1 (en) 1996-03-04 1997-09-10 Soremartec S.A. Isolation and sequencing of the hazel FAd2-N gene
US6194167B1 (en) 1997-02-18 2001-02-27 Washington State University Research Foundation ω-3 fatty acid desaturase
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
AU720677B2 (en) 1997-04-11 2000-06-08 Abbott Laboratories Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
WO1999064616A2 (en) 1998-06-12 1999-12-16 Abbott Laboratories Polyunsaturated fatty acids in plants
EP1895009A1 (en) 1998-06-12 2008-03-05 Calgene LLC Polyunsaturated fatty acids in plants
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US20030163845A1 (en) 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
CA2346006A1 (en) 1998-10-09 2000-04-20 Merck & Co., Inc. Delta 6 fatty acid desaturase
NZ512656A (en) 1998-12-07 2003-09-26 Univ Washington Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
CN1247784C (zh) 2000-02-09 2006-03-29 巴斯福股份公司 新延伸酶基因以及制备多不饱和脂肪酸的方法
AU2001264161A1 (en) 2000-05-09 2001-11-20 Bioriginal Food And Science Corp. Production of conjugated linoleic and linolenic acids in plants
JP4071622B2 (ja) 2000-09-28 2008-04-02 バイオリジナル フード アンド サイエンス コーポレーション 脂肪酸不飽和化酵素ファミリーのメンバーであるｆａｄ４、ｆａｄ５、ｆａｄ５−２およびｆａｄ６、ならびにそれらの使用方法
US7297523B2 (en) 2000-11-29 2007-11-20 Xenon Pharmaceuticals Inc. Human elongase genes and uses thereof
US20020067845A1 (en) 2000-12-05 2002-06-06 Griffis Andrew J. Sensor apparatus and method for use in imaging features of an object
DE10102337A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
DE10102338A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
AU2002309482B2 (en) 2001-01-25 2007-08-30 Abbott Laboratories Desaturase genes and uses thereof
AU2002258505A1 (en) 2001-03-12 2002-09-24 The General Hospital Corporation Compositions and methods for modifying the content of polyunsaturated fatty acids in mammalian cells
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
US7045683B2 (en) 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
EP2255668A3 (en) 2001-05-14 2012-04-04 Martek Biosciences Corporation Production and Use of a Polar Lipid-Rich Fraction Containing Omega-3 and/or Omega-6 Highly Unsaturated Fatty Acids from Microbes, Genetically Modified Plant Seeds and Marine Organisms
US7211656B2 (en) 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
AU2003258496A1 (en) 2002-07-03 2004-01-23 Basf Plant Science Gmbh Method for the production of conjugated polyunsaturated fatty acids comprising at least two double bonds in plants
ES2525212T3 (es) 2002-12-19 2014-12-19 University Of Bristol Procedimiento novedoso de producción de ácidos grasos poliinsaturados
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
ATE517984T1 (de) 2003-02-27 2011-08-15 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren
CA2868312A1 (en) 2003-03-31 2004-10-14 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
EP1613744B1 (de) 2003-04-08 2015-09-09 BASF Plant Science GmbH Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
PT2166069T (pt) * 2003-08-01 2016-09-13 Basf Plant Science Gmbh Método de produção de ácidos gordos polinsaturados em organismos transgénicos
JP4567047B2 (ja) * 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
CA3045858C (en) 2004-02-27 2023-02-21 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic plants
WO2005083053A2 (de) 2004-02-27 2005-09-09 Basf Plant Science Gmbh Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
ES2715640T3 (es) 2004-04-22 2019-06-05 Commw Scient Ind Res Org Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
DE102005013779A1 (de) * 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
DE102006008030A1 (de) 2006-02-21 2007-08-23 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten Fettsäuren
AR059376A1 (es) * 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
JP2011519552A (ja) * 2008-04-25 2011-07-14 ビーエーエスエフ プラント サイエンス ゲーエムベーハー 植物種子油
EP2281051B1 (en) * 2008-04-30 2015-03-11 Rothamsted Research Limited Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
JP6068800B2 (ja) 2008-11-18 2017-01-25 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション オメガ−３脂肪酸を産生するための酵素および方法
DE112010002353T5 (de) * 2009-06-08 2012-08-09 Basf Plant Science Company Gmbh Neue fettsäure-elongations-komponenten und anwenduingen davon
CA3037072C (en) * 2009-07-17 2022-07-26 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
MX2016003737A (es) 2013-09-25 2017-01-12 Basf Se Microorganismo recombinante para la mejora de produccion de productos quimicos finos.
KR102321146B1 (ko) 2013-12-13 2021-11-03 바스프 에스이 정밀 화학물질의 개선된 생산을 위한 재조합 미생물
WO2015140226A1 (en) 2014-03-19 2015-09-24 Basf Se The use of glycerol with limited feed of carbohydrates for fermentation
MX2017011976A (es) 2015-03-18 2018-02-09 Basf Se Microorganismo recombinante para la produccion mejorada de quimicos finos.
MX2017015668A (es) 2015-06-04 2018-08-15 Basf Se Microorganismos recombinante para la produccion mejorada de quimicos finos.
EP3307902A1 (en) 2015-06-12 2018-04-18 Basf Se Recombinant microorganism for improved production of alanine

Also Published As

Publication number Publication date
BRPI0708082A2 (pt) 2011-05-17
EP1991684B1 (de) 2013-04-10
US20160369290A1 (en) 2016-12-22
US20210163975A1 (en) 2021-06-03
CA2985908A1 (en) 2007-08-30
US10533182B2 (en) 2020-01-14
US20190390215A1 (en) 2019-12-26
CA2642929C (en) 2018-06-05
US20190218568A1 (en) 2019-07-18
WO2007096387A1 (de) 2007-08-30
US20220213497A1 (en) 2022-07-07
US10533183B2 (en) 2020-01-14
US20190218567A1 (en) 2019-07-18
US10190131B2 (en) 2019-01-29
US10301638B2 (en) 2019-05-28
EP1991684A1 (de) 2008-11-19
AU2007217554A1 (en) 2007-08-30
AU2013260698B2 (en) 2016-05-19
CA2642929A1 (en) 2007-08-30
US20100227924A1 (en) 2010-09-09
CA2985908C (en) 2019-11-26

Similar Documents

Publication Publication Date Title
AR059376A1 (es) Procedimiento para la produccion de acidos grasos poliinsaturados
WO2010023202A3 (en) Nucleic acids encoding desaturases and modified plant oil
AR092778A1 (es) Produccion de dha (acido docosahexaenoico) y otros acidos grasos poli insaturados de cadena larga en plantas
AR110075A1 (es) Un método para edición basal en plantas
ES2568803T3 (es) Reducción del contenido de ácidos grasos saturados en semillas de plantas
ES2531391T3 (es) Delta-5 desaturasas y procedimiento para la preparación de ácidos grasos poliinsaturados en organismos transgénicos no humanos
AR062001A1 (es) Desaturasas de acido graso de tetraselmis suecica
SG10201810439SA (en) Production of long chain polyunsaturated fatty acids in plant cells
AR077809A1 (es) Organismos homocigotas para una modificacion dirigida
CO6960508A2 (es) Composiciones y métodos para incrementar la resistencia a nematodos en plantas
CL2012003412A1 (es) Molécula de adn definida por secuencias especificas que derivan del evento mon 88302 de brassica napus, microorganismo que la comprende, método para detectar dicha molécula de adn; y procedimiento para controlar malezas en las vencindades de las plantas que comprenden el evento mon 88302.
BRPI0510132A (pt) sìntese de ácidos graxos poliinsaturados de cadeia longa por células recombinantes
CO6592070A2 (es) Remoción de transgenes en organismos geneticamente modificados
AR081201A1 (es) Produccion de dha (acido docosahexanoico ) y otros lc-pufas( acidos grasos poliinsaturados de cadena larga ) en plantas
AR111157A2 (es) Secuencia reguladora de plantas
BRPI0709317A2 (pt) àleos vegetais que contÉm Ácidos graxos poliinsaturados
AR074783A1 (es) Metodos y composiciones para expresar uno o mas productos de un acido nucleico exogeno integrado al locus zp15 de una celula vegetal
BR112014032741A2 (pt) lipase em esterificação de ácidos graxos de cadeia curta
AR065241A1 (es) Promotores de gen vegetal inducibles por nematodos y metodos para su uso
UY36909A (es) Promotor y 3’ utr de plantas para la expresión del transgén
AR087432A1 (es) Procedimiento de preparacion de amino-acidos o esteres que comprende una etapa de metatesis
CL2017001519A1 (es) Supresión de arni parental de gen hunchback para el control de las plagas de hemípteros
AR068542A1 (es) Plantas que tienen biomasa aumentada
AR072157A1 (es) Metodos y medios para aumentar la eficacia en el uso de agua en plantas
BR112016026171A2 (pt) método para produzir produtos químicos com 6 carbonos a partir de ácidos graxos de cadeia longa por meio de clivagem oxidativa

Legal Events

Date Code Title Description
FC Refusal