OA08235A - Composés intermediaires de carbapénem et leur procédé de préparation. - Google Patents

Composés intermediaires de carbapénem et leur procédé de préparation.

Info

Publication number: OA08235A
Authority: OA; OAPI
Prior art keywords: carbapenem; preparation process; intermediate compounds; compounds; preparation
Prior art date: 1985-04-22

Application number

OA58839A

Other languages

English (en)

Inventor

Guy Roberge

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-22

Filing date

1986-04-18

Publication date

1987-10-30

1986-04-18 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-10-30 Publication of OA08235A publication Critical patent/OA08235A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
- C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
- C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
- C07C245/18—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/12—Organo silicon halides
- C07F7/16—Preparation thereof from silicon and halogenated hydrocarbons direct synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

OA58839A 1985-04-22 1986-04-18 Composés intermediaires de carbapénem et leur procédé de préparation. OA08235A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/725,594 US4683296A (en)	1983-03-07	1985-04-22	Carbapenem intermediates

Publications (1)

Publication Number	Publication Date
OA08235A true OA08235A (fr)	1987-10-30

Family

ID=24915191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA58839A OA08235A (fr)	1985-04-22	1986-04-18	Composés intermediaires de carbapénem et leur procédé de préparation.

Country Status (35)

Country	Link
US (1)	US4683296A (fr)
JP (1)	JPS61275284A (fr)
KR (1)	KR890004347B1 (fr)
CN (1)	CN86102077A (fr)
AR (1)	AR244236A1 (fr)
AT (1)	AT386208B (fr)
AU (1)	AU599022B2 (fr)
BE (1)	BE904645A (fr)
CA (1)	CA1302426C (fr)
CH (1)	CH667273A5 (fr)
CS (1)	CS266585B2 (fr)
DD (1)	DD251352A5 (fr)
DE (1)	DE3613366A1 (fr)
DK (1)	DK182386A (fr)
ES (1)	ES8708234A1 (fr)
FI (1)	FI861633A (fr)
FR (1)	FR2580653B1 (fr)
GB (1)	GB2173801B (fr)
GR (1)	GR861064B (fr)
HU (1)	HU195824B (fr)
IE (1)	IE59042B1 (fr)
IL (1)	IL78533A (fr)
IT (1)	IT1213061B (fr)
LU (1)	LU86401A1 (fr)
MY (1)	MY102926A (fr)
NL (1)	NL8601010A (fr)
NO (1)	NO861558L (fr)
NZ (1)	NZ215263A (fr)
OA (1)	OA08235A (fr)
PT (1)	PT82435B (fr)
SE (1)	SE8601824L (fr)
YU (1)	YU43696B (fr)
ZA (1)	ZA862987B (fr)
ZM (1)	ZM6286A1 (fr)
ZW (1)	ZW8986A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4772683A (en) *	1986-02-24	1988-09-20	Bristol-Myers Company	High percentage beta-yield synthesis of carbapenem intermediates
JP2675625B2 (ja) *	1989-01-12	1997-11-12	鐘淵化学工業株式会社	エノールシリルエーテル化合物の製造方法
NZ234411A (en) *	1989-07-18	1991-05-28	Merck & Co Inc	Preparation of 2-diazo-3-silyloxy-3-butenoate esters
US5340927A (en) *	1989-07-18	1994-08-23	Merck & Co., Inc.	Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates
DE4014649A1 (de) *	1990-05-08	1991-11-14	Hoechst Ag	Neue mehrfunktionelle verbindungen mit (alpha)-diazo-ss-ketoester- und sulfonsaeureester-einheiten, verfahren zu ihrer herstellung und deren verwendung
JP2000166962A (ja) *	1998-12-08	2000-06-20	Tatsu Ifukube	触覚刺激装置及び方法
ES2335889T3 (es)	2003-08-28	2010-04-06	Ranbaxy Laboratories Limited	Proceso para la preparacion de esteres de acido 2-diazo-3-trimetilsililoxi-3-butenoico.
US20070037971A1 (en) *	2005-07-29	2007-02-15	Meeran Hashim Nizar P N	Process for desilylation of carbapenem intermediates
ES2391713T3 (es) *	2008-07-30	2012-11-29	Ranbaxy Laboratories Limited	Proceso para la preparación de compuestos de carbapenem
WO2011048583A1 (fr)	2009-10-23	2011-04-28	Ranbaxy Laboratories Limited	Procédé pour la préparation de composés de carbapénème
CN102690282A (zh) *	2011-07-07	2012-09-26	深圳市海滨制药有限公司	晶体形式的1β甲基碳青霉烯类抗生素中间体及其制备方法
CN102643211A (zh) *	2012-04-10	2012-08-22	平顶山佳瑞高科实业有限公司	一种2-重氮乙酰乙酸对硝基苄酯的制备方法
WO2017132321A1 (fr)	2016-01-29	2017-08-03	The Johns Hopkins University	Nouveaux inhibiteurs de la croissance bactérienne
CN106565535B (zh) *	2016-11-15	2018-07-17	山西师范大学	2-重氮-1-芳基酮类化合物的制备方法
CN107556212B (zh) *	2017-09-14	2020-03-24	台州昌霖化工科技有限公司	一种制备2-重氮乙酰乙酸对硝基苄酯的方法
CN114516820A (zh) *	2022-02-25	2022-05-20	山东艾孚特科技有限公司	一种制备2-重氮乙酰乙酸对硝基苄酯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3274758D1 (en) *	1981-04-03	1987-01-29	Matsushita Electric Ind Co Ltd	Method of cooking
US4444685A (en) *	1981-04-27	1984-04-24	Merck & Co., Inc.	Stereospecific synthesis of thienamycin from penicillin
CA1190236A (fr) *	1981-10-23	1985-07-09	Edward J.J. Grabowski	Synthese d'un antibiotique
US4525582A (en) *	1982-06-22	1985-06-25	Merck & Co., Inc.	Silyl, benzyl, p-nitrobenyl, or methyl esters of diazoacetate, a synthon used in the conversion of penicillin to thienamycin
NZ205626A (en) *	1982-09-28	1986-12-05	Bristol Myers Co	Carbapenem antibiotics
CA1220215A (fr) *	1983-03-07	1987-04-07	Yasutsugu Ueda	Intermediaires du carbapenem

1985
- 1985-04-22 US US06/725,594 patent/US4683296A/en not_active Expired - Fee Related
1986
- 1986-02-21 NZ NZ215263A patent/NZ215263A/xx unknown
- 1986-03-28 CN CN198686102077A patent/CN86102077A/zh active Pending
- 1986-04-16 AU AU56167/86A patent/AU599022B2/en not_active Ceased
- 1986-04-17 FI FI861633A patent/FI861633A/fi not_active Application Discontinuation
- 1986-04-18 AR AR86303698A patent/AR244236A1/es active
- 1986-04-18 IL IL78533A patent/IL78533A/xx not_active IP Right Cessation
- 1986-04-18 OA OA58839A patent/OA08235A/fr unknown
- 1986-04-18 FR FR868605640A patent/FR2580653B1/fr not_active Expired
- 1986-04-21 SE SE8601824A patent/SE8601824L/ unknown
- 1986-04-21 ZW ZW89/86A patent/ZW8986A1/xx unknown
- 1986-04-21 ZM ZM62/86A patent/ZM6286A1/xx unknown
- 1986-04-21 GB GB8609662A patent/GB2173801B/en not_active Expired
- 1986-04-21 KR KR1019860003078A patent/KR890004347B1/ko not_active IP Right Cessation
- 1986-04-21 LU LU86401A patent/LU86401A1/fr unknown
- 1986-04-21 CH CH1600/86A patent/CH667273A5/de not_active IP Right Cessation
- 1986-04-21 IT IT8620164A patent/IT1213061B/it active
- 1986-04-21 IE IE104786A patent/IE59042B1/en not_active IP Right Cessation
- 1986-04-21 PT PT82435A patent/PT82435B/pt not_active IP Right Cessation
- 1986-04-21 DD DD86289445A patent/DD251352A5/de not_active IP Right Cessation
- 1986-04-21 BE BE0/216571A patent/BE904645A/fr not_active IP Right Cessation
- 1986-04-21 DK DK182386A patent/DK182386A/da not_active Application Discontinuation
- 1986-04-21 NO NO861558A patent/NO861558L/no unknown
- 1986-04-21 ES ES554217A patent/ES8708234A1/es not_active Expired
- 1986-04-21 NL NL8601010A patent/NL8601010A/nl not_active Application Discontinuation
- 1986-04-21 CS CS862873A patent/CS266585B2/cs unknown
- 1986-04-21 ZA ZA862987A patent/ZA862987B/xx unknown
- 1986-04-21 DE DE19863613366 patent/DE3613366A1/de not_active Ceased
- 1986-04-22 GR GR861064A patent/GR861064B/el unknown
- 1986-04-22 AT AT0106886A patent/AT386208B/de not_active IP Right Cessation
- 1986-04-22 HU HU861677A patent/HU195824B/hu not_active IP Right Cessation
- 1986-04-22 CA CA000507256A patent/CA1302426C/fr not_active Expired - Fee Related
- 1986-04-22 JP JP61091418A patent/JPS61275284A/ja active Granted
- 1986-04-22 YU YU658/86A patent/YU43696B/xx unknown
1987
- 1987-09-29 MY MYPI87002268A patent/MY102926A/en unknown

Also Published As

Publication number	Publication date
ZW8986A1 (en)	1986-12-03
AT386208B (de)	1988-07-25
IE861047L (en)	1986-10-22
GR861064B (en)	1986-09-01
ZM6286A1 (en)	1987-04-30
CS287386A2 (en)	1989-04-14
MY102926A (en)	1993-03-31
JPS61275284A (ja)	1986-12-05
IL78533A0 (en)	1986-08-31
FI861633A (fi)	1986-10-23
AU5616786A (en)	1986-11-06
YU43696B (en)	1989-10-31
FI861633A0 (fi)	1986-04-17
IT8620164A0 (it)	1986-04-21
ZA862987B (en)	1987-12-30
GB2173801A (en)	1986-10-22
ATA106886A (de)	1987-12-15
DE3613366A1 (de)	1986-11-20
NZ215263A (en)	1989-03-29
IE59042B1 (en)	1993-12-15
ES554217A0 (es)	1987-10-01
BE904645A (fr)	1986-10-21
IT1213061B (it)	1989-12-07
DK182386A (da)	1986-10-23
HU195824B (en)	1988-07-28
AR244236A1 (es)	1993-10-29
CS266585B2 (en)	1990-01-12
NO861558L (no)	1986-10-23
PT82435A (en)	1986-05-01
YU65886A (en)	1988-04-30
GB8609662D0 (en)	1986-05-29
SE8601824L (sv)	1986-10-23
LU86401A1 (fr)	1986-11-05
JPS6358836B2 (fr)	1988-11-17
DD251352A5 (de)	1987-11-11
GB2173801B (en)	1989-08-23
CN86102077A (zh)	1987-01-28
ES8708234A1 (es)	1987-10-01
DK182386D0 (da)	1986-04-21
PT82435B (pt)	1988-08-17
FR2580653B1 (fr)	1989-06-16
SE8601824D0 (sv)	1986-04-21
CA1302426C (fr)	1992-06-02
KR860008191A (ko)	1986-11-12
HUT41040A (en)	1987-03-30
FR2580653A1 (fr)	1986-10-24
NL8601010A (nl)	1986-11-17
US4683296A (en)	1987-07-28
KR890004347B1 (ko)	1989-10-31
IL78533A (en)	1992-05-25
AU599022B2 (en)	1990-07-12
CH667273A5 (de)	1988-09-30

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OA08235A (fr)	1987-10-30	Composés intermediaires de carbapénem et leur procédé de préparation.
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PT83643B (pt)	1988-10-14	Processo de preparacao de derivados de quinoleina
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GB8527809D0 (en)	1985-12-18	Process for preparation of silibinin
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OA06951A (fr)	1983-07-31	Dérivés de la thiéno-pyridinone, leur procédé de préparation et leur application thérapeutique.
OA06201A (fr)	1981-06-30	Procédé de préparation de nouveaux composés d'urée et amido .
OA07984A (fr)	1987-01-31	Procédé stéréocontrolé de préparation d'acetoxyazetidione.
OA07674A (fr)	1985-05-23	Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.
FR2355020A1 (fr)	1978-01-13	Antibiotiques de b-lactames et leur procede de preparation
FI885045A (fi)	1989-05-03	Menetelmä polynukleotidien valmistamiseksi
PT84624B (pt)	1989-11-30	Processo de preparacao de imidazois substituidos
FI863282A0 (fi)	1986-08-13	Uusi menetelmä valmistaa metyleenidioksifenantreeniyhdisteitä
OA06451A (fr)	1981-07-31	Procédé de préparation de composés B-lactame.
DZ851A1 (fr)	2004-09-13	Nouveaux dérivés de la pyridine et leur procédé depréparation.
FR2566776B1 (fr)	1986-12-26	Procede de preparation de metalloporphyrines
DZ779A1 (fr)	2004-09-13	Nouveaux dérivés de la quinoléine ainse que leur procédé de préparation.
FR2557877B1 (fr)	1989-06-16	Procede de preparation d'alcaloides dimeres