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NO981609D0 - Fusjonerte tropanderivater som inhiberer for neurotransmitteropptak - Google Patents

Fusjonerte tropanderivater som inhiberer for neurotransmitteropptak

Info

Publication number
NO981609D0
NO981609D0 NO981609A NO981609A NO981609D0 NO 981609 D0 NO981609 D0 NO 981609D0 NO 981609 A NO981609 A NO 981609A NO 981609 A NO981609 A NO 981609A NO 981609 D0 NO981609 D0 NO 981609D0
Authority
NO
Norway
Prior art keywords
alkyl
alkynyl
alkenyl
aryl
arylalkyl
Prior art date
Application number
NO981609A
Other languages
English (en)
Other versions
NO981609L (no
NO309569B1 (no
Inventor
Jaergen Scheel-Krueger
Gunnar M Olsen
Bjarne Hugo Dahl
Leif Helth Jensen
Elsebeth Istergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of NO981609D0 publication Critical patent/NO981609D0/no
Publication of NO981609L publication Critical patent/NO981609L/no
Publication of NO309569B1 publication Critical patent/NO309569B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO981609A 1995-11-02 1998-04-07 Fusjonerte tropanderivater som inhiberer for neurotransmitteropptak NO309569B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK122395 1995-11-02
DK14696 1996-02-13
PCT/EP1996/004793 WO1997016451A1 (en) 1995-11-02 1996-11-04 Fused tropane-derivatives as neurotransmitter reuptake inhibitors

Publications (3)

Publication Number Publication Date
NO981609D0 true NO981609D0 (no) 1998-04-07
NO981609L NO981609L (no) 1998-06-26
NO309569B1 NO309569B1 (no) 2001-02-19

Family

ID=26063395

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981609A NO309569B1 (no) 1995-11-02 1998-04-07 Fusjonerte tropanderivater som inhiberer for neurotransmitteropptak

Country Status (25)

Country Link
US (1) US5998405A (no)
EP (1) EP0858461B1 (no)
JP (1) JP3157839B2 (no)
KR (1) KR100277482B1 (no)
CN (1) CN1060775C (no)
AT (1) ATE224392T1 (no)
AU (1) AU702720B2 (no)
BR (1) BR9611300A (no)
CA (1) CA2236707C (no)
CZ (1) CZ285571B6 (no)
DE (1) DE69623799T2 (no)
DK (1) DK0858461T3 (no)
EE (1) EE03566B1 (no)
HK (1) HK1016984A1 (no)
HU (1) HUP9802534A3 (no)
IL (1) IL123898A (no)
IS (1) IS4708A (no)
NO (1) NO309569B1 (no)
NZ (1) NZ321970A (no)
PL (1) PL184843B1 (no)
RU (1) RU2162469C2 (no)
SK (1) SK282944B6 (no)
TR (1) TR199800780T2 (no)
UA (1) UA47442C2 (no)
WO (1) WO1997016451A1 (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706880B2 (en) 1990-08-09 2004-03-16 Research Triangle Institute Cocaine receptor binding ligands
US6329520B1 (en) * 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
US6150376A (en) * 1998-08-05 2000-11-21 Georgetown University Bi- and tri-cyclic aza compounds and their uses
US6093724A (en) 1998-08-18 2000-07-25 Ucb, S.A. Muscarinic agonists and antagonists
EP1220854A2 (en) 1999-09-27 2002-07-10 University Georgetown Novel tropane analogs
US6479509B1 (en) 2000-05-22 2002-11-12 Research Triangle Institute Method of promoting smoking cessation
AU2001265820A1 (en) * 2000-07-04 2002-01-14 Neurosearch A/S Steric isomers of fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US7160899B2 (en) 2001-04-09 2007-01-09 Neurosearch A/S Adenosine A2A receptor antangonists combined with neurotrophic activity compounds in the treatment of Parkinson's disease
WO2002094827A1 (en) * 2001-05-23 2002-11-28 Neurosearch A/S Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
AR035898A1 (es) 2001-05-25 2004-07-21 Wyeth Corp Aril-8-azabiciclo[3.2.1]octanos, un proceso para su preparacion, una formulacion y el uso de dichos compuestos para la manufactura de un medicamento para el tratamiento de la depresion
ATE345135T1 (de) 2001-11-30 2006-12-15 Neurosearch As Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungen
CA2515584A1 (en) 2003-02-12 2004-08-26 Neurosearch A/S 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2004072075A1 (en) 2003-02-12 2004-08-26 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP2272847A1 (en) 2005-04-08 2011-01-12 NeuroSearch A/S Enantiomers and their use as monoamine neurotransmitter re-uptake inhibitors
ATE481386T1 (de) 2005-06-28 2010-10-15 Neurosearch As Neue 3-aza-spiroä5.5üundec-8-en derivate und deren verwendung als inhibitoren der wiederaufnahme von monoaminneurotransmittern
JP2008546826A (ja) 2005-06-28 2008-12-25 ノイロサーチ アクティーゼルスカブ 新規な３，９−ジアザ−スピロ［５．５］ウンデカン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用
TW200800980A (en) 2006-02-17 2008-01-01 Neurosearch As Novel compounds
MX2011011904A (es) 2009-05-15 2011-12-08 Neurosearch As Derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.
BRPI1015043A2 (pt) * 2009-06-19 2019-07-09 Abbott Lab derivados de diazahomoadamantano e métodos de uso dos mesmos
WO2011032903A1 (en) 2009-09-21 2011-03-24 Neurosearch A/S Piperazinyl-alkyl-benzoimidazol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2011092061A1 (en) 2010-01-29 2011-08-04 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2011117289A1 (en) 2010-03-25 2011-09-29 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neuro-transmitter re-uptake inhibitors
WO2012000881A1 (en) 2010-07-02 2012-01-05 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP6052524B1 (ja) * 2015-07-30 2016-12-27 秋夫 湯田 持ち運び設置が容易な手提げハンドルの付いた薪ストーブ。
TW202409027A (zh) 2022-07-08 2024-03-01 丹麥商創始人製藥股份有限公司 用於女性性功能障礙的治療之化合物
WO2024089247A1 (en) 2022-10-28 2024-05-02 Initiator Pharma A/S Compound for treatment of pain
WO2024146892A1 (en) 2023-01-03 2024-07-11 Initiator Pharma A/S Compound for treatment of erectile dysfunction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
CA2187309C (en) * 1994-04-19 2000-11-21 Peter Moldt Tropane-2-aldoxime derivatives as neurotransmitter reuptake inhibitors

Also Published As

Publication number Publication date
HUP9802534A3 (en) 1999-06-28
SK282944B6 (sk) 2003-01-09
AU7563196A (en) 1997-05-22
EP0858461A1 (en) 1998-08-19
SK42298A3 (en) 1998-10-07
CZ285571B6 (cs) 1999-09-15
US5998405A (en) 1999-12-07
EP0858461B1 (en) 2002-09-18
NO981609L (no) 1998-06-26
BR9611300A (pt) 1999-06-15
AU702720B2 (en) 1999-03-04
JPH11514638A (ja) 1999-12-14
HK1016984A1 (en) 1999-11-12
ATE224392T1 (de) 2002-10-15
MX9803554A (es) 1998-09-30
KR100277482B1 (ko) 2001-01-15
KR19990064111A (ko) 1999-07-26
IS4708A (is) 1998-03-31
CN1201461A (zh) 1998-12-09
IL123898A (en) 2001-08-08
CZ113898A3 (cs) 1998-07-15
CN1060775C (zh) 2001-01-17
PL184843B1 (pl) 2002-12-31
HUP9802534A2 (hu) 1999-04-28
NO309569B1 (no) 2001-02-19
EE03566B1 (et) 2001-12-17
TR199800780T2 (xx) 1998-07-21
DE69623799T2 (de) 2003-01-30
CA2236707A1 (en) 1997-05-09
WO1997016451A1 (en) 1997-05-09
RU2162469C2 (ru) 2001-01-27
IL123898A0 (en) 1998-10-30
EE9800100A (et) 1998-10-15
DK0858461T3 (da) 2003-01-27
PL326448A1 (en) 1998-09-28
JP3157839B2 (ja) 2001-04-16
UA47442C2 (uk) 2002-07-15
CA2236707C (en) 2002-08-06
DE69623799D1 (de) 2002-10-24
NZ321970A (en) 2000-02-28

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