[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

NO901247L - Monoklonale antistoffer som reagerer med kakektin. - Google Patents

Monoklonale antistoffer som reagerer med kakektin.

Info

Publication number
NO901247L
NO901247L NO90901247A NO901247A NO901247L NO 901247 L NO901247 L NO 901247L NO 90901247 A NO90901247 A NO 90901247A NO 901247 A NO901247 A NO 901247A NO 901247 L NO901247 L NO 901247L
Authority
NO
Norway
Prior art keywords
monoclonal antibodies
cocketin
reactivated
antibodies
cell lines
Prior art date
Application number
NO90901247A
Other languages
English (en)
Other versions
NO179615C (no
NO179615B (no
NO901247D0 (no
Inventor
George Kuo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of NO901247L publication Critical patent/NO901247L/no
Publication of NO901247D0 publication Critical patent/NO901247D0/no
Priority to NO952509A priority Critical patent/NO180637C/no
Publication of NO179615B publication Critical patent/NO179615B/no
Publication of NO179615C publication Critical patent/NO179615C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO901247A 1988-07-18 1990-03-16 Monoklonale antistoffer eller fragmenter derav som reagerer med kakektin, cellelinjer som produserer dem, prövesett som omfatter dem, samt anvendelse derav in vitro NO179615C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO952509A NO180637C (no) 1988-07-18 1995-06-22 Fremgangsmåte for fremstilling av monoklonale antistoffer eller fragmenter derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22020688A 1988-07-18 1988-07-18
PCT/US1989/003025 WO1990000902A1 (en) 1988-07-18 1989-07-12 Monoclonal antibodies reactive with cachectin

Publications (4)

Publication Number Publication Date
NO901247L true NO901247L (no) 1990-03-16
NO901247D0 NO901247D0 (no) 1990-03-16
NO179615B NO179615B (no) 1996-08-05
NO179615C NO179615C (no) 1996-11-13

Family

ID=22822529

Family Applications (1)

Application Number Title Priority Date Filing Date
NO901247A NO179615C (no) 1988-07-18 1990-03-16 Monoklonale antistoffer eller fragmenter derav som reagerer med kakektin, cellelinjer som produserer dem, prövesett som omfatter dem, samt anvendelse derav in vitro

Country Status (16)

Country Link
US (1) US5658803A (no)
EP (1) EP0351789B1 (no)
JP (1) JP2638652B2 (no)
AT (1) ATE173766T1 (no)
AU (1) AU626572B2 (no)
CA (1) CA1340018C (no)
DE (1) DE68928857T2 (no)
DK (1) DK69890A (no)
ES (1) ES2124209T3 (no)
FI (1) FI101937B1 (no)
IL (1) IL90990A (no)
NO (1) NO179615C (no)
NZ (1) NZ229922A (no)
PT (1) PT91201B (no)
WO (1) WO1990000902A1 (no)
ZA (1) ZA895372B (no)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225254A1 (en) * 1989-08-07 2003-12-04 Rathjen Deborah Ann Tumour necrosis factor binding ligands
US6448380B2 (en) 1989-08-07 2002-09-10 Peptech Limited Tumor necrosis factor antibodies
WO1991002078A1 (en) * 1989-08-07 1991-02-21 Peptide Technology Ltd Tumour necrosis factor binding ligands
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
GB8918232D0 (en) * 1989-08-10 1989-09-20 Opal Stephen M Pharmaceutical product for the treatment of septic shock
WO1991002756A1 (en) * 1989-08-16 1991-03-07 Cetus Corporation Prohormone cleavage site blocking antibody
DE4037604A1 (de) * 1990-04-25 1991-10-31 Bayer Ag Verwendung von anti-tnf-antikoerpern als arzneimittel bei der behandlung von ischaemien und deren folgen
WO1992002822A1 (en) * 1990-08-06 1992-02-20 Cetus Corporation Methods for the identification of cytokine convertase inhibitors
US5958413A (en) * 1990-11-01 1999-09-28 Celltech Limited Use of antibodies to TNF or fragments derived thereof and xanthine derivatives for combination therapy and compositions therefor
GB9028123D0 (en) * 1990-12-28 1991-02-13 Erba Carlo Spa Monoclonal antibodies against human tumor necrosis factor alpha
CA2100084A1 (en) * 1991-01-11 1992-07-12 James R. Rusche Method of preventing inflammatory damage
EP1905782A1 (en) * 1991-03-18 2008-04-02 New York University Monoclonal and chimeric antibodies specific for human tumor necrosis factor
US7192584B2 (en) 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
US5919452A (en) * 1991-03-18 1999-07-06 New York University Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
US5698195A (en) * 1991-03-18 1997-12-16 New York University Medical Center Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
US6277969B1 (en) 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US5656272A (en) * 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
US6284471B1 (en) 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
EP0525570A3 (en) * 1991-07-31 1993-10-06 Miles Inc. Anti-idiotypic antibodies that mimic tnf
DK0585705T3 (da) * 1992-08-28 1999-07-26 Bayer Ag Anvendelse af monoklone anti-TNF-antistoffer til behandling af bakteriel meningitis
ES2108460T3 (es) * 1993-06-03 1997-12-16 Therapeutic Antibodies Inc Fragmentos de anticuerpos en terapeutica.
NZ278607A (en) * 1994-02-07 1999-05-28 Knoll Ag Use of tnf antagonists for treating disorders involving elevated serum levels of il-6 wherein the serum levels are 500pg/ml or above
WO1996008516A1 (en) * 1994-09-15 1996-03-21 Verigen, Inc. PORCINE ANTIBODIES TO TNF-α(ALPHA)
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
NZ512006A (en) 1996-02-09 2005-05-27 Abbott Biotech Ltd Medical treatment with human TNF-alpha antibodies
DE19746868A1 (de) * 1997-10-23 1999-04-29 Knoll Ag Verwendung von TNF-Antagonisten als Arzneimittel zur Behandlung von septischen Erkrankungen
UA81743C2 (uk) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
CA2385745C (en) 2001-06-08 2015-02-17 Abbott Laboratories (Bermuda) Ltd. Methods of administering anti-tnf.alpha. antibodies
TWI334439B (en) 2001-08-01 2010-12-11 Centocor Inc Anti-tnf antibodies, compositions, methods and uses
MY150740A (en) 2002-10-24 2014-02-28 Abbvie Biotechnology Ltd Low dose methods for treating disorders in which tnf? activity is detrimental
CN100434440C (zh) 2002-12-02 2008-11-19 阿布格尼克斯公司 针对肿瘤坏死因子的抗体及其用途
US20050045635A1 (en) * 2003-09-03 2005-03-03 Jane Dong Containers for storing articles
TWI556829B (zh) 2004-04-09 2016-11-11 艾伯維生物技術有限責任公司 用於治療ＴＮＦα相關失調症之多重可變劑量療法
CA2608728A1 (en) 2005-05-16 2006-11-23 Abbott Biotechnology Ltd. Use of tnfa inhibitor for treatment of erosive polyarthritis
WO2007075283A2 (en) * 2005-12-06 2007-07-05 Amgen Inc. Polishing steps used in multi-step protein purification processes
NZ571479A (en) 2006-04-05 2012-10-26 Abbott Biotech Ltd Antibody purification
EP2007426A4 (en) 2006-04-10 2010-06-16 Abbott Biotech Ltd COMPOSITIONS FOR THE TREATMENT OF PSORIASTIC POLYARTHRITIS AND THEIR APPLICATIONS
US9605064B2 (en) 2006-04-10 2017-03-28 Abbvie Biotechnology Ltd Methods and compositions for treatment of skin disorders
EP2010214A4 (en) 2006-04-10 2010-06-16 Abbott Biotech Ltd USES AND COMPOSITIONS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS
EP2171451A4 (en) 2007-06-11 2011-12-07 Abbott Biotech Ltd METHOD FOR TREATING JUVENILIAN IDIOPATHIC ARTHRITIS
AU2009204863B2 (en) 2008-01-15 2015-07-16 AbbVie Deutschland GmbH & Co. KG Powdered protein compositions and methods of making same
US8415291B2 (en) 2008-10-31 2013-04-09 Centocor Ortho Biotech Inc. Anti-TNF alpha fibronectin type III domain based scaffold compositions, methods and uses
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
SG11201504249XA (en) 2012-09-02 2015-07-30 Abbvie Inc Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
AU2014215639B2 (en) 2013-01-25 2017-03-23 Thymon, Llc Compositions for selective reduction of circulating bioactive soluble TNF and methods for treating TNF-mediated disease
CA2905010A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
US10465003B2 (en) 2016-02-05 2019-11-05 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
CN110234351A (zh) 2017-01-30 2019-09-13 詹森生物科技公司 用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法
AU2017398101A1 (en) 2017-02-07 2019-08-01 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, and methods for the treatment of active Ankylosing Spondylitis
CN113874073A (zh) 2019-05-23 2021-12-31 詹森生物科技公司 用针对IL-23和TNFα的抗体的联合疗法治疗炎性肠病的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603106A (en) * 1982-02-22 1986-07-29 The Rockefeller University Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
US4684623A (en) * 1985-05-02 1987-08-04 The Board Of Trustees Of The Cetus Corporation Use of tumor necrosis factor as a weight regulator
US4870163A (en) * 1985-08-29 1989-09-26 New York Blood Center, Inc. Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor
JPS63501724A (ja) * 1985-12-05 1988-07-14 バイオジェン インコーポレイテッド 腫瘍壊死因子及び抗生物質及び腫瘍処理方法の組合せ
US4834976A (en) * 1986-07-03 1989-05-30 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
DE3631229A1 (de) * 1986-09-13 1988-03-24 Basf Ag Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung

Also Published As

Publication number Publication date
ES2124209T3 (es) 1999-02-01
NO179615C (no) 1996-11-13
CA1340018C (en) 1998-09-01
US5658803A (en) 1997-08-19
ZA895372B (en) 1990-04-25
DK69890A (da) 1990-05-15
EP0351789A3 (en) 1990-08-01
EP0351789B1 (en) 1998-11-25
IL90990A0 (en) 1990-02-09
EP0351789A2 (en) 1990-01-24
DE68928857T2 (de) 1999-08-05
NZ229922A (en) 1992-04-28
IL90990A (en) 1994-10-21
JP2638652B2 (ja) 1997-08-06
FI101937B (fi) 1998-09-30
NO179615B (no) 1996-08-05
PT91201B (pt) 1996-12-31
ATE173766T1 (de) 1998-12-15
JPH03501330A (ja) 1991-03-28
NO901247D0 (no) 1990-03-16
FI901344A0 (fi) 1990-03-16
FI101937B1 (fi) 1998-09-30
DK69890D0 (da) 1990-03-16
DE68928857D1 (de) 1999-01-07
PT91201A (pt) 1990-02-08
AU626572B2 (en) 1992-08-06
WO1990000902A1 (en) 1990-02-08
AU3970389A (en) 1990-02-19

Similar Documents

Publication Publication Date Title
NO901247D0 (no) Monoklonale antistoffer som reagerer med kakektin.
AU4472793A (en) Methods for diagnosis and therapy using defined regions of the T cell antigen receptor
DE69514342D1 (de) Modifizierte polypeptide mit erhoehter biologischer aktivitaet
DE68924477D1 (de) Gleitkommaeinheit mit gleichzeitiger Multiplikation und Addition.
DE3481035D1 (de) Ibuprofen, flurbiprofen und deren therapeutische verwendung.
DE68905667D1 (de) Ultraschall-diagnostisches geraet.
FR2631239B1 (fr) Anticorps monoclonal humain et hybridome le produisant
AU2456888A (en) Monoclonal antibodies specific for HIV and hybridomas for their production
ES546701A0 (es) Procedimiento para preparar un agente terapeutico a base de celulas tumorales humanas y eventualmente, neuraminidasa.
NO981454D0 (no) Anti-FAS-antistoffer
ZA849576B (en) 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases
NO894187D0 (no) Terapeutiske forbindelser.
EP0274847A3 (en) A-associated h-antigens, monoclonal antibodies specific thereto and methods for employing the same in blood typing
IL91649A0 (en) Hybrid monoclonal antibodies,their production and use
NO894090L (no) Ribbeplate med styreskinnestol.
DE68910151D1 (de) Pilzkultur.
EP0272113A3 (en) Anti-human cancer monoclonal antibodies
ATE99332T1 (de) Monoklonale antikoerper gegen menschliche interleukin-4 und die sie erzeugenden hybridomen.
ATE84069T1 (de) Murin-hybridoma lym-2 und diagnostikantikoerper, der dadurch hergestellt ist.
DE3582664D1 (de) Stuetzvorrichtung fuer den menschlichen koerper.
FI880188A0 (fi) Wobbler med flere funktioner.
IT8215234V0 (it) Schermo riflettente per l abbronzatura solare completa ed omogenea del corpo
ES1006440Y (es) Plantilla terapeutica.
DK147986D0 (da) Den flexible figur
ATE96270T1 (de) Pilzkultur.

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2003