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NO900831L - Fremgangsmaate for fremstilling av piperidinforbindelser. - Google Patents

Fremgangsmaate for fremstilling av piperidinforbindelser.

Info

Publication number
NO900831L
NO900831L NO90900831A NO900831A NO900831L NO 900831 L NO900831 L NO 900831L NO 90900831 A NO90900831 A NO 90900831A NO 900831 A NO900831 A NO 900831A NO 900831 L NO900831 L NO 900831L
Authority
NO
Norway
Prior art keywords
piperide
compounds
procedure
preparation
alkynyl
Prior art date
Application number
NO90900831A
Other languages
English (en)
Other versions
NO900831D0 (no
Inventor
Per Sauerberg
Preben H Olesen
Charles H Mitch
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK82589A external-priority patent/DK82589A/da
Priority claimed from DK231589A external-priority patent/DK231589D0/da
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of NO900831D0 publication Critical patent/NO900831D0/no
Publication of NO900831L publication Critical patent/NO900831L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Forbindelse med formel I. hvor Z er oxygen eller svovel,. R er H,_-alkyl,_-cykloalkyl,_-alkenyl eller C_-alkynyl,. og er uavhengig av hverandre calky1c-10alkeny1-10" alkynyl, C_-aikoxy, C_-cyklo-alkyl, Cj^_^Q-alkylamino,_io~ alkylaminomethyl, C_-alkoxymethyl, io, C_-alkoxyimino-methyl, halogen eller amino, eller et salt derav med en farmasøytisk aksep-tabel syre. Forbindelsene kan anvendes ved stimulering av ce kognitive funk-sjoner i forhjernen og hippocampus hos pattedyr, inkludert mennesker, og ved behandling avlzheimers sykdom.Fremstilling av forbindelsene er beskrevet.
NO90900831A 1989-02-22 1990-02-21 Fremgangsmaate for fremstilling av piperidinforbindelser. NO900831L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK82589A DK82589A (da) 1989-02-22 1989-02-22 Piperidinforbindelser, deres fremstilling og anvendelse
DK231589A DK231589D0 (da) 1989-05-12 1989-05-12 Piperidinforbindelser og deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
NO900831D0 NO900831D0 (no) 1990-02-21
NO900831L true NO900831L (no) 1990-08-23

Family

ID=26064725

Family Applications (2)

Application Number Title Priority Date Filing Date
NO90900831A NO900831L (no) 1989-02-22 1990-02-21 Fremgangsmaate for fremstilling av piperidinforbindelser.
NO900830A NO179639C (no) 1989-02-22 1990-02-21 Analogifremgangsmåte for fremstilling av terapeutisk aktive, substituerte piperidinforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO900830A NO179639C (no) 1989-02-22 1990-02-21 Analogifremgangsmåte for fremstilling av terapeutisk aktive, substituerte piperidinforbindelser

Country Status (22)

Country Link
US (5) US5043345A (no)
EP (2) EP0384285A3 (no)
JP (2) JPH02255680A (no)
KR (1) KR0163763B1 (no)
CN (1) CN1028105C (no)
AR (1) AR247565A1 (no)
AT (1) ATE123030T1 (no)
AU (2) AU4999690A (no)
CA (2) CA2010579A1 (no)
DE (1) DE69019550T2 (no)
DK (1) DK0384288T3 (no)
ES (1) ES2072323T3 (no)
FI (2) FI95704C (no)
GR (1) GR3017062T3 (no)
HU (2) HU221623B1 (no)
IE (1) IE69672B1 (no)
IL (2) IL93352A (no)
NO (2) NO900831L (no)
NZ (1) NZ232615A (no)
PH (1) PH26465A (no)
PT (2) PT93242A (no)
RU (1) RU2042676C1 (no)

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Also Published As

Publication number Publication date
EP0384288B1 (en) 1995-05-24
NO900830D0 (no) 1990-02-21
NO179639C (no) 1996-11-20
PT93241B (pt) 1996-01-31
PT93242A (pt) 1990-08-31
IL93423A0 (en) 1990-11-29
JPH02255680A (ja) 1990-10-16
DK0384288T3 (da) 1995-10-02
AU4999690A (en) 1990-08-30
US5284859A (en) 1994-02-08
HUT58326A (en) 1992-02-28
NZ232615A (en) 1992-06-25
US5712297A (en) 1998-01-27
FI900887A7 (fi) 1990-08-23
KR0163763B1 (ko) 1998-12-01
CA2010578A1 (en) 1990-08-22
CN1028105C (zh) 1995-04-05
FI900887A0 (fi) 1990-02-22
FI95704B (fi) 1995-11-30
JP2921578B2 (ja) 1999-07-19
HU211705A9 (en) 1995-12-28
US5559138A (en) 1996-09-24
CN1045104A (zh) 1990-09-05
IL93352A (en) 1994-08-26
FI900886A0 (fi) 1990-02-22
DE69019550T2 (de) 1995-10-05
EP0384288A2 (en) 1990-08-29
RU2042676C1 (ru) 1995-08-27
EP0384288A3 (en) 1991-04-10
PH26465A (en) 1992-07-27
JPH02255679A (ja) 1990-10-16
HU900884D0 (en) 1990-05-28
EP0384285A3 (en) 1991-04-24
IL93352A0 (en) 1990-11-29
FI95704C (fi) 1996-03-11
EP0384285A2 (en) 1990-08-29
AR247565A1 (es) 1995-01-31
GR3017062T3 (en) 1995-11-30
ATE123030T1 (de) 1995-06-15
AU629302B2 (en) 1992-10-01
US5041455A (en) 1991-08-20
HU221623B1 (hu) 2002-12-28
DE69019550D1 (de) 1995-06-29
IE69672B1 (en) 1996-10-02
NO179639B (no) 1996-08-12
KR910015569A (ko) 1991-09-30
AU4999790A (en) 1990-08-30
US5043345A (en) 1991-08-27
PT93241A (pt) 1990-08-31
NO900830L (no) 1990-08-23
NO900831D0 (no) 1990-02-21
CA2010579A1 (en) 1990-08-22
CA2010578C (en) 2000-05-23
IE900504L (en) 1990-08-22
ES2072323T3 (es) 1995-07-16

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