HUT58326A - Process for producing pipeidine derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing pipeidine derivatives and pharmaceutical compositions containing them

Info

Publication number: HUT58326A
Authority: HU; Hungary
Prior art keywords: pipeidine; derivatives; producing; pharmaceutical compositions; compositions containing
Prior art date: 1989-02-22

Application number

HU90884A

Other languages

Hungarian (hu)

Other versions

HU221623B1 (en

HU900884D0 (en

Inventor

Per Sauerberg

Preben Houlberg Olesen

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-22

Filing date

1990-02-21

Publication date

1992-02-28

1989-02-22 Priority claimed from DK82589A external-priority patent/DK82589A/en

1989-05-12 Priority claimed from DK231589A external-priority patent/DK231589D0/en

1990-02-21 Application filed by Ferrosan As filed Critical Ferrosan As

1990-05-28 Publication of HU900884D0 publication Critical patent/HU900884D0/en

1992-02-28 Publication of HUT58326A publication Critical patent/HUT58326A/en

2002-12-28 Publication of HU221623B1 publication Critical patent/HU221623B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

HU9000884A 1989-02-22 1990-02-21 Process for producing piperidine derivatives and pharmaceutical compositions containing them HU221623B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK82589A DK82589A (en)	1989-02-22	1989-02-22	PIPERIDE CONNECTIONS, THEIR PREPARATION AND USE
DK231589A DK231589D0 (en)	1989-05-12	1989-05-12	PIPERIDE CONNECTIONS AND THEIR PRODUCTION AND USE

Publications (3)

Publication Number	Publication Date
HU900884D0 HU900884D0 (en)	1990-05-28
HUT58326A true HUT58326A (en)	1992-02-28
HU221623B1 HU221623B1 (en)	2002-12-28

Family

ID=26064725

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HU9000884A HU221623B1 (en)	1989-02-22	1990-02-21	Process for producing piperidine derivatives and pharmaceutical compositions containing them
HU95P/P00607P HU211705A9 (en)	1989-02-22	1995-06-29	Piperidine compounds, their preparation and use

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HU95P/P00607P HU211705A9 (en)	1989-02-22	1995-06-29	Piperidine compounds, their preparation and use

Country Status (22)

Country	Link
US (5)	US5043345A (en)
EP (2)	EP0384288B1 (en)
JP (2)	JP2921578B2 (en)
KR (1)	KR0163763B1 (en)
CN (1)	CN1028105C (en)
AR (1)	AR247565A1 (en)
AT (1)	ATE123030T1 (en)
AU (2)	AU4999690A (en)
CA (2)	CA2010579A1 (en)
DE (1)	DE69019550T2 (en)
DK (1)	DK0384288T3 (en)
ES (1)	ES2072323T3 (en)
FI (2)	FI95704C (en)
GR (1)	GR3017062T3 (en)
HU (2)	HU221623B1 (en)
IE (1)	IE69672B1 (en)
IL (2)	IL93352A (en)
NO (2)	NO179639C (en)
NZ (1)	NZ232615A (en)
PH (1)	PH26465A (en)
PT (2)	PT93242A (en)
RU (1)	RU2042676C1 (en)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
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EP0372125A1 (en) *	1988-11-08	1990-06-13	Akzo N.V.	Oxazole and thiazole derivatives
US5260311A (en) *	1989-02-22	1993-11-09	Novo Nordisk A/S	Piperidine compounds and their use
US5264444A (en) *	1989-02-22	1993-11-23	Novo Nordisk A/S	Piperidine compounds and use
US5043345A (en) *	1989-02-22	1991-08-27	Novo Nordisk A/S	Piperidine compounds and their preparation and use
US5328925A (en) *	1989-02-22	1994-07-12	Novo Nordisk A/S	Piperidine compounds and their use
EP0459568A3 (en) *	1990-05-31	1992-09-30	Merck Sharp & Dohme Ltd.	Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
US5376668A (en) *	1990-08-21	1994-12-27	Novo Nordisk A/S	Heterocyclic compounds
USRE35822E (en) *	1990-08-21	1998-06-09	Novo Nordisk A/S	Heterocyclic compounds
DK198390D0 (en) *	1990-08-21	1990-08-21	Novo Nordisk As	HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
US5418240A (en) *	1990-08-21	1995-05-23	Novo Nordisk A/S	Heterocyclic compounds and their preparation and use
DK198590D0 (en) *	1990-08-21	1990-08-21	Novo Nordisk As	HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
US5527813A (en) *	1990-08-21	1996-06-18	Novo Nordisk A/S	Heterocyclic compounds and their preparation and use
DK198490D0 (en) *	1990-08-21	1990-08-21	Novo Nordisk As	HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
ES2113939T3 (en) *	1990-11-29	1998-05-16	Allergan Inc	USE OF PIRIDINE DERIVATIVES IN THE TREATMENT OF EYE HYPERTENSION.
EP0492903A1 (en) *	1990-12-21	1992-07-01	MERCK SHARP & DOHME LTD.	Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
IE922270A1 (en) *	1991-07-26	1993-01-27	Akzo Nv	Pyrazole derivatives
US5641791A (en) *	1991-08-13	1997-06-24	Novo Nordisk A.S	Heterocyclic compounds and their preparation and use
US5175166A (en) *	1991-08-27	1992-12-29	The University Of Toledo	Muscarinic agonists
WO1993014089A1 (en) *	1992-01-13	1993-07-22	Novo Nordisk A/S	Heterocyclic compounds and their preparation and use
US5244906A (en) *	1992-01-23	1993-09-14	Dowelanco	Insect control with substituted oxadiazole and thiadiazole compounds
DE69325662T2 (en) *	1992-10-23	2000-02-10	Merck Sharp & Dohme Ltd., Hoddesdon	DOPAMINE RECEPTOR SUBTYPE LIGANDS
PT703915E (en) *	1993-06-04	2001-03-30	Novo Nordisk As	XAMONELINE TARTRATO
US5753683A (en) *	1993-08-19	1998-05-19	Novo Nordisk A/S	Antipsychotic method
ATE218864T1 (en) *	1993-08-19	2002-06-15	Novo Nordisk As	USE OF PIPERIDINE DERIVATIVES IN THE TREATMENT OF SCHIZOPHRENIA
US5545638A (en) *	1993-12-21	1996-08-13	Novo Nordisk A/S	Method of treating gastrointestinal motility disorders
IL112024A (en) *	1993-12-21	1999-07-14	Novo Nordisk As	Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders
US5998404A (en)	1994-10-24	1999-12-07	Eli Lilly And Company	Heterocyclic compounds and their use
US5821370A (en) *	1994-10-24	1998-10-13	Eli Lilly And Company	Heterocyclic compounds and their preparation and use
US5605908A (en) *	1994-10-24	1997-02-25	Eli Lilly And Company	Heterocyclic compounds and their use
JPH10508028A (en) *	1994-10-31	1998-08-04	イーライ・リリー・アンド・カンパニー	How to treat anxiety
US5488056A (en) *	1994-10-31	1996-01-30	Eli Lilly And Company	Method for treating anxiety
US5574028A (en) *	1994-10-31	1996-11-12	Eli Lilly And Company	Method for treating anxiety
US5726193A (en) *	1994-10-31	1998-03-10	Eli Lilly And Company	Method for treating anxiety
US5484794A (en) *	1994-11-09	1996-01-16	Eli Lilly And Company	Method for treating anxiety
US5565475A (en) *	1994-11-08	1996-10-15	Muhlhauser; Mark A.	Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
US5612351A (en) *	1994-11-08	1997-03-18	Novo Nordisk A/S	Method of treating urinary bladder dysfunctions
TW304167B (en) *	1995-01-30	1997-05-01	Lilly Co Eli
US5605701A (en) *	1995-02-17	1997-02-25	Eli Lilly And Company	Transdermal formulation
US5763457A (en)	1995-11-13	1998-06-09	Eli Lilly And Company	Method for treating anxiety
US5852037A (en) *	1995-11-13	1998-12-22	Eli Lilly And Company	Method for treating anxiety
CA2239301A1 (en) *	1995-12-06	1997-06-12	Charles Howard Mitch	Composition for treating pain
JP2000501711A (en) *	1995-12-07	2000-02-15	イーライ・リリー・アンド・カンパニー	How to treat pain
GB9603755D0 (en) *	1996-02-22	1996-04-24	Pfizer Ltd	Therapeutic agents
CA2250472A1 (en) *	1996-04-23	1997-10-30	Steven James Quimby	Heterocyclic compounds
JP2000509043A (en) *	1996-04-23	2000-07-18	イーライ・リリー・アンド・カンパニー	Heterocyclic compounds
EP0910566B1 (en) *	1996-04-24	2003-09-17	Novo Nordisk A/S	Heterocyclic compounds and their preparation and use
ATE213413T1 (en) *	1996-08-01	2002-03-15	Lilly Co Eli	USE OF 3-(4-HEXYLOXY-1,2,5-THIADIAZOLE-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE (XANOMELINE) FOR THE TREATMENT OF BIPOLAR DISORDER
EP0821957A3 (en) *	1996-08-01	1998-04-22	Eli Lilly And Company	Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating substance abuse
US6043258A (en) *	1996-08-01	2000-03-28	Eli Lilly And Company	Method for treating disruptive behavior disorders with xanomeline
US6117890A (en) *	1996-08-01	2000-09-12	Eli Lilly And Company	Method for treating bipolar disorder
US6090829A (en) *	1996-08-01	2000-07-18	Eli Lilly And Company	Method for treating excessive aggression
EP0821954A1 (en) *	1996-08-01	1998-02-04	Eli Lilly And Company	Method for treating mental retardation
EP0821959A3 (en) *	1996-08-01	1998-09-16	Eli Lilly And Company	Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine for treating nicotine withdrawal
EP0821956A1 (en) *	1996-08-01	1998-02-04	Eli Lilly And Company	Method for treating disruptive behavior disorders
EP0821958A3 (en) *	1996-08-01	1998-07-08	Eli Lilly And Company	Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating excessive aggression
WO1998017214A1 (en) *	1996-10-23	1998-04-30	Eli Lilly And Company	Method for treating dementia due to aids
WO1998053820A1 (en)	1997-05-29	1998-12-03	H. Lundbeck A/S	Treatment of schizophrenia and psychosis
US6034108A (en) *	1997-07-28	2000-03-07	Eli Lilly And Company	Method for treating mental retardation
US6528529B1 (en)	1998-03-31	2003-03-04	Acadia Pharmaceuticals Inc.	Compounds with activity on muscarinic receptors
US6096767A (en)	1999-01-22	2000-08-01	The University Of Toledo	Muscarinic receptor agonists
US6211204B1 (en)	1999-01-22	2001-04-03	University Of Toledo	Muscarinic receptor agonists
US6376675B2 (en) *	1999-01-22	2002-04-23	The University Of Toledo	Muscarinic receptor agonists
US20040023951A1 (en) *	2001-06-18	2004-02-05	Bymaster Franklin Porter	Combination therapy for treatment of psychoses
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) *	2005-08-26	2010-03-16	Braincells Inc	Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
CN1821243B (en) *	2005-08-30	2010-12-08	北京大学	Substituted pyridine M1 receptor excitomotor, its preparing process and its use
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20090012101A1 (en) *	2005-12-27	2009-01-08	University Of Toledo	Mucarinic Agonists and Methods of Use Thereof
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
AU2007249435A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 HT receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US20110294835A1 (en)	2008-05-15	2011-12-01	The Board Of Trustees Of The University Of Illinois	Muscarinic Agonists as Cognitive Enhancers
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
US10265311B2 (en)	2009-07-22	2019-04-23	PureTech Health LLC	Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
CA2804215C (en)	2009-07-22	2019-10-01	Eric Elenko	Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
NO3034079T3 (en)	2010-11-15	2018-06-09
WO2012149524A1 (en)	2011-04-29	2012-11-01	The University Of Toledo	Muscarinic agonists as enhancers of working memory and cognitive flexibility
NZ722077A (en)	2013-12-20	2021-12-24	Agenebio Inc	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
MA42624A (en)	2015-06-19	2021-04-28	Agenebio Inc	BENZODIAZEPINE DERIVATIVES, COMPOSITIONS AND TREATMENT METHODS FOR COGNITIVE DEFICIENCY
WO2017044693A1 (en)	2015-09-11	2017-03-16	Chase Pharmaceuticals Corporation	Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system
US20180170941A1 (en)	2016-12-19	2018-06-21	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US11505555B2 (en)	2016-12-19	2022-11-22	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
CN112601749B (en)	2018-06-19	2024-03-26	艾吉因生物股份有限公司	Benzodiazepine derivatives, compositions and methods for treating cognitive impairment
US10933020B2 (en)	2018-09-28	2021-03-02	Karuna Therapeutics, Inc.	Compositions and methods for treating disorders ameliorated by muscarinic receptor activation
WO2021097427A1 (en)	2019-11-15	2021-05-20	Karuna Therapeutics, Inc.	Xanomeline derivatives and methods for treating neurological disorders
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WO2024039886A1 (en)	2022-08-19	2024-02-22	Agenebio, Inc.	Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
IL83275A (en) *	1986-09-08	1994-02-27	Novo Nordisk As	Substituted 1, 2, 4- oxadiazolyl piperidine compounds, their preparation and pharmaceutical compositions containing them
US5017618A (en) *	1987-03-16	1991-05-21	University Of Florida	Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers
GB8714789D0 (en) *	1987-06-24	1987-07-29	Lundbeck & Co As H	Heterocyclic compounds
NZ225999A (en) *	1987-09-10	1992-04-28	Merck Sharp & Dohme	Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) *	1987-11-13	1995-06-14	Novo Nordisk As	Azabicyclic compounds and their preparation and use
NZ227841A (en) *	1988-02-12	1991-08-27	Merck Sharp & Dohme	Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DK162892C (en) *	1988-07-04	1992-05-11	Novo Nordisk As	1,2,5,6-TETRAHYDROPYRIDINE COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
US5328925A (en) *	1989-02-22	1994-07-12	Novo Nordisk A/S	Piperidine compounds and their use
US5264444A (en) *	1989-02-22	1993-11-23	Novo Nordisk A/S	Piperidine compounds and use
US5260311A (en) *	1989-02-22	1993-11-09	Novo Nordisk A/S	Piperidine compounds and their use
US5043345A (en) *	1989-02-22	1991-08-27	Novo Nordisk A/S	Piperidine compounds and their preparation and use
DK198490D0 (en) *	1990-08-21	1990-08-21	Novo Nordisk As	HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
DK198390D0 (en) *	1990-08-21	1990-08-21	Novo Nordisk As	HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
US5175166A (en) *	1991-08-27	1992-12-29	The University Of Toledo	Muscarinic agonists

1989
- 1989-08-31 US US07/401,370 patent/US5043345A/en not_active Expired - Lifetime
1990
- 1990-02-12 IL IL9335290A patent/IL93352A/en not_active IP Right Cessation
- 1990-02-13 IE IE50490A patent/IE69672B1/en not_active IP Right Cessation
- 1990-02-14 ES ES90102913T patent/ES2072323T3/en not_active Expired - Lifetime
- 1990-02-14 EP EP90102913A patent/EP0384288B1/en not_active Expired - Lifetime
- 1990-02-14 DE DE69019550T patent/DE69019550T2/en not_active Expired - Fee Related
- 1990-02-14 PH PH40049A patent/PH26465A/en unknown
- 1990-02-14 AT AT90102913T patent/ATE123030T1/en not_active IP Right Cessation
- 1990-02-14 DK DK90102913.2T patent/DK0384288T3/en active
- 1990-02-14 EP EP19900102889 patent/EP0384285A3/en not_active Withdrawn
- 1990-02-16 IL IL93423A patent/IL93423A0/en unknown
- 1990-02-20 AU AU49996/90A patent/AU4999690A/en not_active Abandoned
- 1990-02-20 US US07/482,272 patent/US5041455A/en not_active Expired - Lifetime
- 1990-02-20 NZ NZ232615A patent/NZ232615A/en unknown
- 1990-02-20 AU AU49997/90A patent/AU629302B2/en not_active Ceased
- 1990-02-21 KR KR1019900002108A patent/KR0163763B1/en not_active IP Right Cessation
- 1990-02-21 RU SU904743296A patent/RU2042676C1/en not_active IP Right Cessation
- 1990-02-21 NO NO900830A patent/NO179639C/en not_active IP Right Cessation
- 1990-02-21 CA CA002010579A patent/CA2010579A1/en not_active Abandoned
- 1990-02-21 NO NO90900831A patent/NO900831L/en unknown
- 1990-02-21 CA CA002010578A patent/CA2010578C/en not_active Expired - Lifetime
- 1990-02-21 AR AR90316209A patent/AR247565A1/en active
- 1990-02-21 HU HU9000884A patent/HU221623B1/en not_active IP Right Cessation
- 1990-02-22 PT PT93242A patent/PT93242A/en not_active Application Discontinuation
- 1990-02-22 FI FI900886A patent/FI95704C/en active IP Right Grant
- 1990-02-22 FI FI900887A patent/FI900887A0/en not_active Application Discontinuation
- 1990-02-22 JP JP2039899A patent/JP2921578B2/en not_active Expired - Fee Related
- 1990-02-22 CN CN90100873A patent/CN1028105C/en not_active Expired - Fee Related
- 1990-02-22 PT PT93241A patent/PT93241B/en not_active IP Right Cessation
- 1990-02-22 JP JP2039900A patent/JPH02255680A/en active Pending
1991
- 1991-08-15 US US07/745,568 patent/US5284859A/en not_active Expired - Lifetime
1995
- 1995-06-07 US US08/472,356 patent/US5559138A/en not_active Expired - Lifetime
- 1995-06-29 HU HU95P/P00607P patent/HU211705A9/en unknown
- 1995-08-09 GR GR950402188T patent/GR3017062T3/en unknown
1996
- 1996-09-23 US US08/717,647 patent/US5712297A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE69672B1 (en)	1996-10-02
AU4999790A (en)	1990-08-30
EP0384285A2 (en)	1990-08-29
US5559138A (en)	1996-09-24
JP2921578B2 (en)	1999-07-19
NO900831L (en)	1990-08-23
ES2072323T3 (en)	1995-07-16
RU2042676C1 (en)	1995-08-27
CN1028105C (en)	1995-04-05
HU211705A9 (en)	1995-12-28
FI900886A0 (en)	1990-02-22
AU4999690A (en)	1990-08-30
KR0163763B1 (en)	1998-12-01
US5043345A (en)	1991-08-27
EP0384285A3 (en)	1991-04-24
CN1045104A (en)	1990-09-05
FI95704C (en)	1996-03-11
AR247565A1 (en)	1995-01-31
NO179639C (en)	1996-11-20
HU221623B1 (en)	2002-12-28
PT93242A (en)	1990-08-31
PT93241A (en)	1990-08-31
FI900887A0 (en)	1990-02-22
AU629302B2 (en)	1992-10-01
IL93423A0 (en)	1990-11-29
IL93352A (en)	1994-08-26
PT93241B (en)	1996-01-31
DE69019550D1 (en)	1995-06-29
JPH02255679A (en)	1990-10-16
DK0384288T3 (en)	1995-10-02
CA2010579A1 (en)	1990-08-22
US5041455A (en)	1991-08-20
NZ232615A (en)	1992-06-25
PH26465A (en)	1992-07-27
JPH02255680A (en)	1990-10-16
EP0384288A3 (en)	1991-04-10
IL93352A0 (en)	1990-11-29
HU900884D0 (en)	1990-05-28
CA2010578A1 (en)	1990-08-22
DE69019550T2 (en)	1995-10-05
EP0384288A2 (en)	1990-08-29
NO179639B (en)	1996-08-12
ATE123030T1 (en)	1995-06-15
NO900830L (en)	1990-08-23
US5284859A (en)	1994-02-08
GR3017062T3 (en)	1995-11-30
CA2010578C (en)	2000-05-23
FI95704B (en)	1995-11-30
NO900830D0 (en)	1990-02-21
NO900831D0 (en)	1990-02-21
KR910015569A (en)	1991-09-30
US5712297A (en)	1998-01-27
IE900504L (en)	1990-08-22
EP0384288B1 (en)	1995-05-24

Publication	Publication Date	Title
HUT58326A (en)	1992-02-28	Process for producing pipeidine derivatives and pharmaceutical compositions containing them
HUT49316A (en)	1989-09-28	Process for producing didehydro-d3-vitamine derivatives and pharmaceutical compositions containing them
HUT48900A (en)	1989-07-28	Process for producing phosphoruus-containing squalene-synthetase inhibitores and pharmaceutical compositions containing them
HUT53644A (en)	1990-11-28	Process for producing pharmaceutical nukleozides and pharmaceutical compositions containing them
HUT48267A (en)	1989-05-29	Process for producing fluoro-citidin derivatives and pharmaceutical compositions containing them
HUT56091A (en)	1991-07-29	Process for producing pyrimidine derivatives and pharmaceutical compositions containing them
HUT58304A (en)	1992-02-28	Process for producing quinazolin-3-alkane-acids and pharmaceutical compositions containing them
HUT53885A (en)	1990-12-28	Process for producing piridazinon derivatives of 2-hydroxy-n-propyl-amines and pharmaceutical compositions containing them
HUT48887A (en)	1989-07-28	Process for producing cyclopentenyl-purin derivatives and pharmaceutical compositions containing them
HUT54139A (en)	1991-01-28	Process for producing n-heteroaryl-4-quinolineamine derivatives and pharmaceutical compositions comprising such compounds
HUT56098A (en)	1991-07-29	Process for producing azanaphtalenesultame derivatives and pharmaceutical compositions containing them
HUT59908A (en)	1992-07-28	Process for producing benzazepine- and benzo-thiazepine derivatives and pharmaceutical compositions containing them
HUT54112A (en)	1991-01-28	Process for producing benzocycloalkane derivatives and pharmaceutical compositions comprising same
HUT49317A (en)	1989-09-28	Process for producing 16-dehydro-d3-vitamine derivatives and pharmaceutical compositions containing them
HUT56078A (en)	1991-07-29	Process for producing piridazine derivatives and pharmaceutical compositions containing them
HUT47079A (en)	1989-01-30	Process for producing n-amino-butyl-n-phenyl-aryl-amide derivatives and pharmaceutical compositions containing them
HUT48870A (en)	1989-07-28	Process for producing aminoalkoxyphenyl derivatives and pharmaceutical compositions comprising same
HU906358D0 (en)	1991-04-29	Process for producing nukleosides and pharmaceutical compositions containing them
HUT56342A (en)	1991-08-28	Process for producing capsoicin derivatives and pharmaceutical compositions comprising such compounds
HUT53625A (en)	1990-11-28	Process for producing 2-iminobenzothiazole derivatives and pharmaceutical compositions comprising same
HUT49871A (en)	1989-11-28	Process for producing indolylpiperidine derivatives and pharmaceutical compositions comprising same
HUT58713A (en)	1992-03-30	Process for producing chromane derivatives and pharmaceutical compositions containing them
HUT43820A (en)	1987-12-28	Process for producing n-(-2-((-2-hydroxy-phenyl-)(-phenyl-)-methylene-aminosquare )-ethyl-)-acetamide derivatives and pharmaceutical compositions containing them
HUT48244A (en)	1989-05-29	Process for producing isoxazol-3-carbolin derivatives and pharmaceutical compositions containing them
HUT50829A (en)	1990-03-28	Process for producing thienoazepines and pharmaceutical compositions comprising same

Legal Events

Date	Code	Title	Description
1992-09-28	DGB9	Succession in title of applicant	Owner name: NOVO NORDISK A/S, DK
2004-11-29	HMM4	Cancellation of final prot. due to non-payment of fee