NO891248L - Fremgangsmaate for fremstilling av aristeromycin/adenosin-derivater. - Google Patents

Fremgangsmaate for fremstilling av aristeromycin/adenosin-derivater.

Info

Publication number: NO891248L
Authority: NO; Norway
Prior art keywords: aristeromycine; procedure; preparation; adenosin; derivatives
Prior art date: 1988-03-25

Application number

NO89891248A

Other languages

English (en)

Other versions

NO171856C (no

NO171856B (no

NO891248D0 (no

Inventor

Michael L Edwards

James R Mccarthy

Nellijunja J Prakash

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-25

Filing date

1989-03-21

Publication date

1989-09-26

1989-03-21 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-03-21 Publication of NO891248D0 publication Critical patent/NO891248D0/no

1989-09-26 Publication of NO891248L publication Critical patent/NO891248L/no

1993-02-01 Publication of NO171856B publication Critical patent/NO171856B/no

1993-05-12 Publication of NO171856C publication Critical patent/NO171856C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO891248A 1988-03-25 1989-03-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive adenosinderivater NO171856C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/173,782 US4996308A (en)	1988-03-25	1988-03-25	Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group

Publications (4)

Publication Number	Publication Date
NO891248D0 NO891248D0 (no)	1989-03-21
NO891248L true NO891248L (no)	1989-09-26
NO171856B NO171856B (no)	1993-02-01
NO171856C NO171856C (no)	1993-05-12

Family

ID=22633462

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO891248A NO171856C (no)	1988-03-25	1989-03-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive adenosinderivater

Country Status (21)

Country	Link
US (1)	US4996308A (no)
EP (1)	EP0334361B1 (no)
JP (1)	JP2829737B2 (no)
KR (1)	KR0135529B1 (no)
CN (1)	CN1023804C (no)
AR (1)	AR247403A1 (no)
AT (1)	ATE121415T1 (no)
AU (1)	AU606792B2 (no)
CA (1)	CA1322195C (no)
DE (1)	DE68922235T2 (no)
DK (1)	DK171645B1 (no)
ES (1)	ES2074060T3 (no)
FI (1)	FI90877C (no)
HU (1)	HU203561B (no)
IE (1)	IE67543B1 (no)
IL (1)	IL89689A0 (no)
NO (1)	NO171856C (no)
NZ (1)	NZ228422A (no)
PH (1)	PH26776A (no)
PT (1)	PT90080B (no)
ZA (1)	ZA892105B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3924424A1 (de) *	1989-07-24	1991-01-31	Boehringer Mannheim Gmbh	Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung
ZA907998B (en) *	1989-10-11	1991-07-31	Merrell Dow Pharma	Inosine/guanosine derivatives as antineoplastic agents
ZA907994B (en) *	1989-10-11	1991-07-31	Merrell Dow Pharma	Novel inosine/guanosine derivatives
GB8926417D0 (en) *	1989-11-22	1990-01-10	Wellcome Found	Heterocyclic compounds
JPH0421682A (ja) *	1990-05-11	1992-01-24	Asahi Chem Ind Co Ltd	２―フルオロネプラノシンａおよびその製造法
GB9205071D0 (en) *	1992-03-09	1992-04-22	Wellcome Found	Therapeutic nucleosides
US5399580A (en) *	1993-03-08	1995-03-21	Burroughs Wellcome Co.	Therapeutic nucleosides-uses
CA2158462A1 (en) *	1993-03-18	1994-09-29	Akira Matsuda	Novel 2'-methylidenenucleotide compounds, methods for production thereof and pharmaceutical use thereof
EP0784624A1 (en) *	1994-10-05	1997-07-23	Chiroscience Limited	Purine and guanine compounds as inhibitors of pnp
GB9600142D0 (en) *	1996-01-05	1996-03-06	Wellcome Found	Chemical compounds
CZ9901996A3 (cs) *	1999-06-04	2001-01-17	Ústav organické chemie a biochemie AV ČR	Nové 6-fenylpurinové 9-ß-D-ribonukleosidy s antineoplastickým účinkem, jejich použití k přípravě farmaceutických preparátů a farmaceutické přípravky, které je obsahují
DE60024257T2 (de)	1999-06-09	2006-07-20	Anticancer Inc., San Diego	Modulatoren der methylierung zur kontrolle von bakterieller virulenz
US6579857B1 (en) *	1999-06-11	2003-06-17	Evanston Northwestern Healthcare Research Institute	Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors
AU2001272923A1 (en) *	2000-05-26	2001-12-11	Idenix (Cayman) Limited	Methods and compositions for treating flaviviruses and pestiviruses
US20040162422A1 (en) *	2001-03-20	2004-08-19	Adrian Hall	Chemical compounds
KR20040036417A (ko) *	2002-10-25	2004-04-30	정낙신	항암 활성을 갖는 티오뉴클레오시드 유도체 및 이를함유하는 약학적 조성물
JP5002851B2 (ja) *	2005-01-20	2012-08-15	独立行政法人理化学研究所	イミダゾピリジン誘導体
CN102746304B (zh) *	2012-06-21	2014-03-19	成都苑东药业有限公司	一种嘌呤胺类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1113851A (en) *	1965-05-29	1968-05-15	Upjohn Co	Decoyinine derivatives
US3472837A (en) *	1966-10-10	1969-10-14	Syntex Corp	Unsaturated nucleosides and process for their preparation
US3575959A (en) *	1969-05-13	1971-04-20	Merck & Co Inc	5'-substituted ribofuranosyl nucleosides
US3585189A (en) *	1969-06-27	1971-06-15	Syntex Corp	Unsaturated nucleosides and processes for their preparation
US3910885A (en) *	1974-03-12	1975-10-07	Syntex Inc	4-Alkoxy nucleosides and intermediates therefore
IL77133A (en) *	1984-12-04	1991-01-31	Lilly Co Eli	Antineoplastic pharmaceutical compositions containing pentofuranoside derivatives,some new such compounds and their preparation
GB8708050D0 (en) *	1987-04-03	1987-05-07	Wellcome Found	Therapeutic nucleosides
NZ225906A (en) *	1987-08-26	1990-10-26	Merrell Dow Pharma	Aristeromycin/adenosine derivatives and pharmaceutical compositions

1988
- 1988-03-25 US US07/173,782 patent/US4996308A/en not_active Expired - Lifetime
1989
- 1989-03-20 CA CA000594206A patent/CA1322195C/en not_active Expired - Fee Related
- 1989-03-20 ZA ZA892105A patent/ZA892105B/xx unknown
- 1989-03-21 NO NO891248A patent/NO171856C/no unknown
- 1989-03-21 NZ NZ228422A patent/NZ228422A/en unknown
- 1989-03-21 FI FI891339A patent/FI90877C/fi not_active IP Right Cessation
- 1989-03-21 IL IL89689A patent/IL89689A0/xx not_active IP Right Cessation
- 1989-03-22 AR AR89313479A patent/AR247403A1/es active
- 1989-03-22 DK DK145289A patent/DK171645B1/da not_active IP Right Cessation
- 1989-03-22 PT PT90080A patent/PT90080B/pt not_active IP Right Cessation
- 1989-03-23 DE DE68922235T patent/DE68922235T2/de not_active Expired - Fee Related
- 1989-03-23 EP EP89105254A patent/EP0334361B1/en not_active Expired - Lifetime
- 1989-03-23 ES ES89105254T patent/ES2074060T3/es not_active Expired - Lifetime
- 1989-03-23 AT AT89105254T patent/ATE121415T1/de not_active IP Right Cessation
- 1989-03-23 IE IE95389A patent/IE67543B1/en not_active IP Right Cessation
- 1989-03-24 CN CN89101682A patent/CN1023804C/zh not_active Expired - Fee Related
- 1989-03-24 HU HU891526A patent/HU203561B/hu unknown
- 1989-03-24 KR KR1019890003722A patent/KR0135529B1/ko not_active IP Right Cessation
- 1989-03-24 JP JP1070752A patent/JP2829737B2/ja not_active Expired - Fee Related
- 1989-03-27 PH PH38380A patent/PH26776A/en unknown
- 1989-03-28 AU AU31737/89A patent/AU606792B2/en not_active Ceased

Also Published As

Publication number	Publication date
FI891339A0 (fi)	1989-03-21
AU3173789A (en)	1989-09-28
FI90877B (fi)	1993-12-31
HU203561B (en)	1991-08-28
IE67543B1 (en)	1996-04-17
HUT49367A (en)	1989-09-28
JP2829737B2 (ja)	1998-12-02
EP0334361A2 (en)	1989-09-27
NO171856C (no)	1993-05-12
EP0334361B1 (en)	1995-04-19
ES2074060T3 (es)	1995-09-01
AU606792B2 (en)	1991-02-14
JPH01283285A (ja)	1989-11-14
IL89689A0 (en)	1989-09-28
AR247403A1 (es)	1994-12-29
EP0334361A3 (en)	1991-04-03
NO171856B (no)	1993-02-01
PH26776A (en)	1992-10-13
NO891248D0 (no)	1989-03-21
KR890014573A (ko)	1989-10-24
IE890953L (en)	1989-09-25
NZ228422A (en)	1991-04-26
PT90080A (pt)	1989-11-10
DK145289A (da)	1989-09-26
DK171645B1 (da)	1997-03-03
FI90877C (fi)	1994-04-11
ZA892105B (en)	1989-11-29
KR0135529B1 (ko)	1998-04-23
PT90080B (pt)	1994-06-30
ATE121415T1 (de)	1995-05-15
DE68922235T2 (de)	1995-08-31
US4996308A (en)	1991-02-26
DK145289D0 (da)	1989-03-22
CN1036579A (zh)	1989-10-25
CA1322195C (en)	1993-09-14
CN1023804C (zh)	1994-02-16
DE68922235D1 (de)	1995-05-24
FI891339A (fi)	1989-09-26

Publication	Publication Date	Title
NO870579L (no)	1987-08-17	Fremgangsmaate for fremstilling av indolizin-derivater.
NO862661D0 (no)	1986-07-01	Fremgangsmaate for fremstilling av n-aralkylpiperidinmethanolderivater.
NO892936D0 (no)	1989-07-17	Fremgangsmaate for fremstilling av furanderivater.
NO865013D0 (no)	1986-12-11	Fremgangsmaate for fremstilling av antibaktercelle kinolon-derivater.
NO891248L (no)	1989-09-26	Fremgangsmaate for fremstilling av aristeromycin/adenosin-derivater.
NO885454L (no)	1990-06-11	Fremgangsmaate for fremstilling av triklormonosilan.
NO883793L (no)	1989-02-27	Fremgangsmaate for fremstilling av nye aristeromycin/adenosinderivater.
NO894210D0 (no)	1989-10-23	Fremgangsmaate for fremstilling av kinolyloxazol-2-oner.
NO894649D0 (no)	1989-11-22	Fremgangsmaate for fremstilling av (s)-alfa-ethyl-2-oxo-1-pyrrolidinacetamid.
NO863251L (no)	1987-02-16	Fremgangsmaate for fremstilling av sphingosinderivater.
NO880910D0 (no)	1988-03-01	Fremgangsmaate for fremstilling av chromonderivater.
NO891588D0 (no)	1989-04-18	Fremgangsmaate for fremstilling av fosfonoalkylpurinderivater.
NO860429L (no)	1986-08-11	Fremgangsmaate for fremstilling av imidazolyl-indol-derivater.
NO890159D0 (no)	1989-01-13	Fremgangsmaate for fremstilling av 1-alkyl-5-nitroimidazoler.
NO883145D0 (no)	1988-07-14	Fremgangsmaate til fremstilling av tienoimidazolderivater.
NO884900L (no)	1989-05-05	Fremgangsmaate for fremstilling av ginkolid-derivater.
NO874199D0 (no)	1987-10-07	Fremgangsmaate for fremstilling av imidazo-pyridinonderivater.
NO894707L (no)	1990-05-28	Fremgangsmaate for fremstilling av benzoksazinderivater.
NO883398D0 (no)	1988-08-01	Fremgangsmaate for fremstilling av benzoksazinderivater.
NO883610D0 (no)	1988-08-12	Fremgangsmaate til fremstilling av substituerte tienoimidazol-derivater.
NO884100L (no)	1989-03-17	Fremgangsmaate for fremstilling av halogentiazolderivater.
NO874698L (no)	1988-05-13	Fremgangsmaate for fremstilling av 2-guanidinothiazolderivater.
NO892813D0 (no)	1989-07-07	Fremgangsmaate til fremstilling av l-alanyl-l-prolin-derivater.
NO862493L (no)	1986-12-22	Fremgangsmaate for fremstilling av 2-halonicergolinderivater.
NO873019D0 (no)	1987-07-20	Fremgangsmaate for fremstilling av tetrahydrobenzotiazolkinolin-derivater.