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NO20090332L - 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler - Google Patents

4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler

Info

Publication number
NO20090332L
NO20090332L NO20090332A NO20090332A NO20090332L NO 20090332 L NO20090332 L NO 20090332L NO 20090332 A NO20090332 A NO 20090332A NO 20090332 A NO20090332 A NO 20090332A NO 20090332 L NO20090332 L NO 20090332L
Authority
NO
Norway
Prior art keywords
arylamino
amino
preparation
antiviral agents
pyrimidine derivatives
Prior art date
Application number
NO20090332A
Other languages
English (en)
Inventor
Michaela Schmidtke
Vadim Makarov
Peter Wutzler
Hans-Martin Dahse
Original Assignee
Dritte Patentportfolio Beteili
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dritte Patentportfolio Beteili filed Critical Dritte Patentportfolio Beteili
Publication of NO20090332L publication Critical patent/NO20090332L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse gjelder 4-amino-3-arylamino-6-arylpyrazolo-[3,4-d]pyrimidinderivater, en fremgangsmåte for fremstilling av disse og anvendelse av dem som antivirale midler. Formålet var å tilveiebringe nye forbindelser som kan benyttes som midler for f.eks. behandling av picornavirusinfeksjoner og som unngår problemer forbundet med kjente medikamenter, nærmere bestemt vedrørende resistens og intoleranse. Dette formålet oppnås ved hjelp av forbindelser med den generelle formel I.
NO20090332A 2006-06-22 2009-01-21 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler NO20090332L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006029074A DE102006029074A1 (de) 2006-06-22 2006-06-22 4-Amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung als antivirale Wirkstoffe
PCT/DE2007/001104 WO2007147401A1 (de) 2006-06-22 2007-06-20 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-derivate, verfahren zu ihrer herstellung und deren verwendung als antivirale wirkstoffe

Publications (1)

Publication Number Publication Date
NO20090332L true NO20090332L (no) 2009-03-12

Family

ID=38606873

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090332A NO20090332L (no) 2006-06-22 2009-01-21 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler

Country Status (18)

Country Link
US (1) US8962634B2 (no)
EP (1) EP2049540B1 (no)
JP (1) JP5171815B2 (no)
KR (1) KR101107839B1 (no)
CN (1) CN101553489B (no)
AT (1) ATE492548T1 (no)
AU (1) AU2007262524B2 (no)
BR (1) BRPI0713488B1 (no)
CA (1) CA2655754C (no)
DE (2) DE102006029074A1 (no)
ES (1) ES2359677T3 (no)
IL (1) IL195837A0 (no)
NO (1) NO20090332L (no)
NZ (1) NZ573849A (no)
RU (1) RU2456288C2 (no)
SG (1) SG173316A1 (no)
WO (1) WO2007147401A1 (no)
ZA (1) ZA200900165B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2751109T3 (en) * 2011-09-02 2017-01-23 Incyte Holdings Corp HETEROCYCLYLAMINES AS PI3K INHIBITORS
BR112014008815B1 (pt) * 2011-10-14 2021-01-12 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg 4-amino-3-fenilamino-6-fenilpirazolo[3,4-d]pirimidina, composição farmacêutica método para preparar uma composição farmacêutica e método para fabricar um 4-amino-3-fenilamino-6- fenilpirazolo[3,4-d]pirimidina
DE102011116373A1 (de) 2011-10-14 2013-04-18 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Methode zur Herstellung von 4-Amino-3-arylamino-6-arylpyrazolo[3, 4-d]pyrimidinen
DE102012004736A1 (de) 2011-10-20 2013-04-25 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-Derivate und deren Verwendung als antivirale Wirkstoffe
WO2016044656A1 (en) 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
EP3064207B1 (en) 2015-03-04 2017-12-20 Scandion Oncology A/S 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965643A (en) * 1960-12-20 Derivatives of pyrazolo
US3551428A (en) * 1956-02-10 1970-12-29 Ciba Geigy Corp New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE1088503B (de) * 1957-12-06 1960-09-08 Ciba Geigy Verfahren zur Herstellung von 3-Amino-pyrazolo-[3,4-d]-pyrimidinen
DE3712735A1 (de) * 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
CA2100863A1 (en) 1991-01-23 1992-07-24 David A. Bullough Adenosine kinase inhibitors
US5294612A (en) * 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
US5646152A (en) 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
CZ27399A3 (cs) * 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
CA2558109A1 (en) * 2004-02-27 2005-09-15 F. Hoffmann-La Roche Ag Heteroaryl-fused pyrazolo derivatives
WO2006035061A1 (en) * 2004-09-30 2006-04-06 Tibotec Pharmaceuticals Ltd. Hcv inhibiting bi-cyclic pyrimidines

Also Published As

Publication number Publication date
NZ573849A (en) 2011-11-25
ZA200900165B (en) 2009-12-30
CN101553489A (zh) 2009-10-07
JP2009541230A (ja) 2009-11-26
ES2359677T3 (es) 2011-05-25
EP2049540B1 (de) 2010-12-22
CA2655754A1 (en) 2007-12-27
WO2007147401A1 (de) 2007-12-27
ATE492548T1 (de) 2011-01-15
RU2456288C2 (ru) 2012-07-20
US8962634B2 (en) 2015-02-24
AU2007262524A1 (en) 2007-12-27
IL195837A0 (en) 2009-09-01
DE102006029074A1 (de) 2007-12-27
DE502007006042D1 (de) 2011-02-03
CA2655754C (en) 2012-02-07
SG173316A1 (en) 2011-08-29
US20100010018A1 (en) 2010-01-14
CN101553489B (zh) 2013-07-17
KR20090071536A (ko) 2009-07-01
AU2007262524B2 (en) 2011-12-01
RU2009101920A (ru) 2010-07-27
KR101107839B1 (ko) 2012-02-09
BRPI0713488B1 (pt) 2022-04-12
BRPI0713488A2 (pt) 2012-10-23
EP2049540A1 (de) 2009-04-22
JP5171815B2 (ja) 2013-03-27

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Legal Events

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