NO20000257L - Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine - Google Patents
Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksineInfo
- Publication number
- NO20000257L NO20000257L NO20000257A NO20000257A NO20000257L NO 20000257 L NO20000257 L NO 20000257L NO 20000257 A NO20000257 A NO 20000257A NO 20000257 A NO20000257 A NO 20000257A NO 20000257 L NO20000257 L NO 20000257L
- Authority
- NO
- Norway
- Prior art keywords
- vaccine
- compositions
- modified immunogenic
- pneumolysin
- immunogenic pneumolysin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5330697P | 1997-07-21 | 1997-07-21 | |
US7345698P | 1998-02-02 | 1998-02-02 | |
PCT/US1998/014716 WO1999003884A2 (fr) | 1997-07-21 | 1998-07-21 | Compositions de pneumolysine immunogene modifiee utiles en tant que vaccins |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20000257D0 NO20000257D0 (no) | 2000-01-19 |
NO20000257L true NO20000257L (no) | 2000-03-21 |
Family
ID=26731692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20000257A NO20000257L (no) | 1997-07-21 | 2000-01-19 | Modifisert immunogent pneumolysin, sammensetninger omfattende dette samt anvendelse derav som vaksine |
Country Status (9)
Country | Link |
---|---|
US (2) | US6764686B2 (fr) |
EP (1) | EP0998557A2 (fr) |
JP (1) | JP2001510031A (fr) |
KR (1) | KR100619350B1 (fr) |
AU (1) | AU740956B2 (fr) |
CA (1) | CA2297374A1 (fr) |
HU (1) | HUP0002475A3 (fr) |
NO (1) | NO20000257L (fr) |
WO (1) | WO1999003884A2 (fr) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
BR0009163A (pt) | 1999-03-19 | 2001-12-26 | Smithkline Beecham Biolog | Vacina |
GB9906437D0 (en) * | 1999-03-19 | 1999-05-12 | Smithkline Beecham Biolog | Vaccine |
GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
EP2258386A3 (fr) | 2002-08-02 | 2011-11-02 | GlaxoSmithKline Biologicals S.A. | Composition vaccinale contre Neisseria |
AU2003278166B2 (en) | 2002-11-01 | 2009-01-29 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
ES2451620T3 (es) | 2002-11-07 | 2014-03-28 | Synergy America, Inc. | Composiciones y métodos destinados a tratar o prevenir la infección neumocócica |
RU2340627C2 (ru) | 2003-03-13 | 2008-12-10 | ГлаксоСмитКлайн Байолоджикалз с.а. | Способ очистки бактериального цитолизина |
CA2539715C (fr) | 2003-10-02 | 2015-02-24 | Glaxosmithkline Biologicals S.A. | Antigenes pertussis et leur utilisation dans la vaccination |
US20120027841A1 (en) | 2004-01-07 | 2012-02-02 | Biomedical Research Models, Inc. | Novel mucosal vaccination approach for herpes simplex virus type-2 |
EP1713917A4 (fr) * | 2004-02-13 | 2009-06-17 | Sanofi Pasteur Ltd | Derives de pneumolysine |
GB0410220D0 (en) * | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
WO2005108419A1 (fr) * | 2004-05-07 | 2005-11-17 | Lea-Ann Kirkham | Proteines mutantes de cytolysine liant le cholesterol |
KR20070085236A (ko) * | 2004-08-23 | 2007-08-27 | 메다렉스, 인코포레이티드 | 뉴몰리신에 대한 결합원 |
GB0421083D0 (en) * | 2004-09-22 | 2004-10-27 | Glaxosmithkline Biolog Sa | Purification process |
GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
JP5579387B2 (ja) | 2005-12-22 | 2014-08-27 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 肺炎連鎖球菌莢膜多糖類コンジュゲートを含むワクチン |
US8617565B2 (en) | 2006-01-17 | 2013-12-31 | Arne Forsgren et al. | Surface exposed Haemophilus influenzae protein (protein E; pE) |
US9370557B2 (en) * | 2006-06-15 | 2016-06-21 | The University Court Of The University Of Glasgow | Adjuvant compounds |
US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
ES2675915T3 (es) | 2006-09-26 | 2018-07-13 | Infectious Disease Research Institute | Composición de vacuna que contiene un adyuvante sintético |
SI2086582T1 (sl) | 2006-10-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | Cepivo, ki obsega emulzijo olja v vodi kot adjuvans |
MX2009003325A (es) | 2006-10-12 | 2009-04-09 | Glaxosmithkline Biolog Sa | Vacuna que comprende un adyuvante de emulsion de aceite en agua. |
US9717788B2 (en) | 2007-03-02 | 2017-08-01 | Glaxosmithkline Biologicals Sa | Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant |
CA2896131C (fr) | 2007-03-02 | 2020-04-07 | Glaxosmithkline Biologicals S.A. | Nouveau procede et nouvelles compositions |
BRPI0810211A2 (pt) * | 2007-04-13 | 2014-10-21 | Univ Oklahoma | Citolisina dependente de colesterol mutante purficada, composição, vacina, método para vacinar um paciente, anticorpo monoclonal, ácido nucléico, e, célula hospedeira. |
EP2687228B1 (fr) | 2007-06-26 | 2017-07-19 | GlaxoSmithKline Biologicals S.A. | Vaccin contenant des conjugues de polysaccharide capsulaire de streptococcus pneumoniae |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
EP2271360B1 (fr) | 2008-04-16 | 2015-09-23 | GlaxoSmithKline Biologicals S.A. | Vaccin |
WO2009143413A1 (fr) * | 2008-05-22 | 2009-11-26 | Children'smedical Center Corporation | Conjugué immunogène synergique protéine de fusion-polysaccharide |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
BRPI0923649A2 (pt) | 2008-12-24 | 2016-01-19 | Netherlands Vaccine Inst | polipeptídeos de pneumolisina (ply) de streptococcus pneumoniae modificados. |
RU2555757C2 (ru) | 2009-03-24 | 2015-07-10 | Новартис Аг | Комбинации менингококкового фактор н-связывающего белка и пневмококковых сахаридных конъюгатов |
HUE031051T2 (en) | 2009-06-05 | 2017-06-28 | Infectious Disease Res Inst | Synthetic glycopyranosyl lipid adjuvant and vaccine compositions containing it |
KR20120081587A (ko) | 2009-09-10 | 2012-07-19 | 노파르티스 아게 | 기도 질병에 대한 조합 백신 |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
EP2544714A1 (fr) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Composition de vaccin |
EP2550289A4 (fr) * | 2010-03-12 | 2013-11-27 | Childrens Medical Center | Nouveaux immunogènes et procédés pour la découverte et le dépistage de ceux-ci |
EA024701B1 (ru) | 2010-04-13 | 2016-10-31 | Селлдекс Терапьютикс Инк. | Антитела, связывающие cd27 человека, и их применение |
GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
WO2012072769A1 (fr) | 2010-12-01 | 2012-06-07 | Novartis Ag | Epitopes rrgb de pneumocoque et combinaisons de variantes |
AU2011336366B2 (en) | 2010-12-03 | 2016-05-12 | Sanofi Pasteur Limited | Composition for immunization against Streptococcus pneumoniae |
GB201022007D0 (en) | 2010-12-24 | 2011-02-02 | Imp Innovations Ltd | DNA-sensor |
JP6054942B2 (ja) | 2011-04-08 | 2016-12-27 | イミューン デザイン コーポレイション | 免疫原性組成物、ならびに体液性および細胞性免疫応答を誘発するための該組成物の使用方法 |
EP2709658A1 (fr) | 2011-05-17 | 2014-03-26 | GlaxoSmithKline Biologicals SA | Vaccin contre streptococcus pneumoniae |
WO2013020090A2 (fr) * | 2011-08-04 | 2013-02-07 | The Regents Of The University Of California | Glycopolypeptides dépourvus de glcnac streptococcique, glucides de paroi cellulaire, vaccins streptococciques et procédés pour les fabriquer et les utiliser |
EP2811981B1 (fr) | 2012-02-07 | 2019-05-08 | Infectious Disease Research Institute | Formulations d'adjuvant amélioré comprenant des agonistes de tlr4 et leurs procédés d'utilisation |
US20150132339A1 (en) | 2012-03-07 | 2015-05-14 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
US9555099B2 (en) | 2012-05-16 | 2017-01-31 | Immune Design Corp. | Vaccines for HSV-2 |
US20140193451A1 (en) * | 2012-10-17 | 2014-07-10 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
CA2897398A1 (fr) | 2013-01-07 | 2014-07-10 | Biomedical Research Models, Inc. | Utilisation de vaccins pour le traitement d'infections par l'herpes simplex virus type 2 |
EP4272750A3 (fr) | 2013-02-07 | 2024-01-24 | Children's Medical Center, Corp. | Antigènes de protéine qui confèrent une protection contre une colonisation et/ou une maladie pneumococcique |
EP3711768A1 (fr) | 2013-04-18 | 2020-09-23 | Immune Design Corp. | Monothérapie de gla destinée à être utilisée dans le traitement du cancer |
US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
EP3915579A1 (fr) | 2013-12-31 | 2021-12-01 | Infectious Disease Research Institute | Formulations de vaccin à flacon unique |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
AU2015349787B2 (en) | 2014-11-21 | 2021-07-29 | The Board Of Regents Of The University Of Oklahoma | Pneumolysin mutants and methods of use thereof |
US20180044429A1 (en) | 2015-03-09 | 2018-02-15 | Celldex Therapeutics, Inc. | Cd27 agonists |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
WO2017176076A1 (fr) | 2016-04-06 | 2017-10-12 | Ewha University - Industry Collaboration Foundation | Peptide ayant la capacité de pénétrer une membrane cellulaire |
SG11201808821WA (en) | 2016-04-18 | 2018-11-29 | Celldex Therapeutics Inc | Agonistic antibodies that bind human cd40 and uses thereof |
WO2017200957A1 (fr) | 2016-05-16 | 2017-11-23 | Infectious Disease Research Institute | Liposomes pégylés et procédés d'utilisation |
WO2017200852A1 (fr) | 2016-05-16 | 2017-11-23 | Infectious Disease Research Institute | Formulation contenant un agoniste de tlr et procédés d'utilisation |
WO2017210364A1 (fr) | 2016-06-01 | 2017-12-07 | Infectious Disease Research Institute | Nanoparticules d'alun contenant un agent d'encollage |
GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
WO2018175783A1 (fr) * | 2017-03-22 | 2018-09-27 | Modernatx, Inc. | Vaccins antibactériens à arn |
KR20240096685A (ko) | 2017-06-15 | 2024-06-26 | 액세스 투 어드밴스드 헬스 인스티튜트 | 나노구조 지질 담체 및 안정적인 에멀션 그리고 이들의 용도 |
JP7339942B2 (ja) | 2017-09-08 | 2023-09-06 | アクセス ツー アドバンスト ヘルス インスティチュート | サポニンを含むリポソーム製剤および使用方法 |
US20210198374A1 (en) | 2018-04-17 | 2021-07-01 | Celldex Therapeutics, Inc. | Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs |
TW202019470A (zh) | 2018-09-12 | 2020-06-01 | 美商艾芬尼維克斯公司 | 多價肺炎球菌疫苗 |
WO2020123444A1 (fr) | 2018-12-11 | 2020-06-18 | Celldex Therapeutics, Inc. | Procédés d'utilisation d'anticorps cd27 en tant que traitement de conditionnement pour une thérapie cellulaire adoptive |
WO2020120569A2 (fr) | 2018-12-12 | 2020-06-18 | Glaxosmithkline Biologicals Sa | Protéines porteuses modifiées pour glycosylation à liaison o |
JP2022532944A (ja) | 2019-05-25 | 2022-07-20 | アクセス ツー アドバンスト ヘルス インスティチュート | アジュバントワクチンエマルジョンを噴霧乾燥するための組成物および方法 |
US20230310323A1 (en) | 2020-09-04 | 2023-10-05 | Access To Advanced Health Institute | Co-lyophilized rna and nanostructured lipid carrier |
AU2022253269A1 (en) | 2021-04-09 | 2023-11-23 | Celldex Therapeutics, Inc. | Antibodies against ilt4, bispecific anti-ilt4/pd-l1 antibody and uses thereof |
KR20240099160A (ko) | 2021-09-09 | 2024-06-28 | 아피니백스, 인크. | 다가 폐렴구균 백신 |
WO2023077521A1 (fr) | 2021-11-08 | 2023-05-11 | Celldex Therapeutics, Inc | Constructions bispécifiques anti-ilt4 et anti-pd-1 |
WO2024052882A1 (fr) | 2022-09-09 | 2024-03-14 | Access To Advanced Health Institute | Composition de vaccin immunogène incorporant une saponine |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990006951A1 (fr) * | 1988-12-16 | 1990-06-28 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Mutants de pneumolysine et vaccins contre le pneumocoque obtenus a partir de tels mutants |
CA2059692C (fr) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Vaccin conjugue de polysaccharide contre les pneumocoques |
EP0687688A1 (fr) | 1993-12-17 | 1995-12-20 | Universidad De Oviedo | Anticorps contre la pneumolysine, et leurs applications |
US5565204A (en) | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
CA2262748A1 (fr) * | 1996-08-12 | 1998-02-19 | Board Of Regents, The University Of Texas System | Definition d'epitopes de la proteine copb de membrane externe de moraxella catarrhalis |
-
1998
- 1998-07-21 EP EP98934590A patent/EP0998557A2/fr not_active Withdrawn
- 1998-07-21 US US09/120,044 patent/US6764686B2/en not_active Expired - Fee Related
- 1998-07-21 KR KR1020007000844A patent/KR100619350B1/ko not_active IP Right Cessation
- 1998-07-21 AU AU84078/98A patent/AU740956B2/en not_active Ceased
- 1998-07-21 JP JP2000503106A patent/JP2001510031A/ja active Pending
- 1998-07-21 HU HU0002475A patent/HUP0002475A3/hu unknown
- 1998-07-21 CA CA002297374A patent/CA2297374A1/fr not_active Abandoned
- 1998-07-21 WO PCT/US1998/014716 patent/WO1999003884A2/fr not_active Application Discontinuation
-
2000
- 2000-01-19 NO NO20000257A patent/NO20000257L/no not_active Application Discontinuation
-
2004
- 2004-02-23 US US10/785,673 patent/US20050070695A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HUP0002475A3 (en) | 2002-01-28 |
CA2297374A1 (fr) | 1999-01-28 |
HUP0002475A2 (hu) | 2000-10-28 |
NO20000257D0 (no) | 2000-01-19 |
KR20010022271A (ko) | 2001-03-15 |
AU8407898A (en) | 1999-02-10 |
KR100619350B1 (ko) | 2006-09-05 |
EP0998557A2 (fr) | 2000-05-10 |
WO1999003884A2 (fr) | 1999-01-28 |
JP2001510031A (ja) | 2001-07-31 |
US20050070695A1 (en) | 2005-03-31 |
WO1999003884A3 (fr) | 1999-04-08 |
US6764686B2 (en) | 2004-07-20 |
AU740956B2 (en) | 2001-11-15 |
US20010014332A1 (en) | 2001-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |