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NO172180C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivater

Info

Publication number
NO172180C
NO172180C NO870771A NO870771A NO172180C NO 172180 C NO172180 C NO 172180C NO 870771 A NO870771 A NO 870771A NO 870771 A NO870771 A NO 870771A NO 172180 C NO172180 C NO 172180C
Authority
NO
Norway
Prior art keywords
radical
carbon atoms
preparation
carboxaldehydoximer
tetrahydropyridine
Prior art date
Application number
NO870771A
Other languages
English (en)
Norwegian (no)
Other versions
NO870771D0 (no
NO870771L (no
NO172180B (no
Inventor
Giulio Galliani
Fernando Barzaghi
Alina Butti
Carla Bonetti
Emilio Toja
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19565/86A external-priority patent/IT1191667B/it
Priority claimed from IT21157/86A external-priority patent/IT1196510B/it
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NO870771D0 publication Critical patent/NO870771D0/no
Publication of NO870771L publication Critical patent/NO870771L/no
Publication of NO172180B publication Critical patent/NO172180B/no
Publication of NO172180C publication Critical patent/NO172180C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
NO870771A 1986-02-27 1987-02-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivater NO172180C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19565/86A IT1191667B (it) 1986-02-27 1986-02-27 Derivati della 1,2,5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci
IT21157/86A IT1196510B (it) 1986-07-17 1986-07-17 Derivati della 1,2-5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci

Publications (4)

Publication Number Publication Date
NO870771D0 NO870771D0 (no) 1987-02-25
NO870771L NO870771L (no) 1987-08-28
NO172180B NO172180B (no) 1993-03-08
NO172180C true NO172180C (no) 1993-06-16

Family

ID=26327212

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870771A NO172180C (no) 1986-02-27 1987-02-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivater

Country Status (20)

Country Link
US (3) US5219872A (de)
EP (1) EP0239445B1 (de)
JP (1) JPH07599B2 (de)
KR (1) KR950005197B1 (de)
AT (1) ATE76066T1 (de)
AU (1) AU588972B2 (de)
BG (1) BG61120B2 (de)
CA (1) CA1327803C (de)
DE (1) DE3778951D1 (de)
DK (1) DK167803B1 (de)
ES (1) ES2032456T3 (de)
FI (1) FI87199C (de)
GR (1) GR3004845T3 (de)
HK (1) HK29797A (de)
HU (1) HU198018B (de)
IE (1) IE59095B1 (de)
IL (1) IL81610A (de)
NO (1) NO172180C (de)
NZ (1) NZ219416A (de)
PT (1) PT84366B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
IT1233446B (it) * 1987-12-30 1992-04-01 Roussel Maestretti Spa Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
DE68907982T2 (de) * 1988-04-15 1994-01-20 Beecham Group Plc Chemische Verbindungen.
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
EP0392803B1 (de) * 1989-04-13 2004-06-16 Beecham Group p.l.c. Chemische Verbindungen
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
JPH06500550A (ja) * 1990-08-24 1994-01-20 ビーチャム・グループ・パブリック・リミテッド・カンパニー アザ二環式化合物、その製造方法および製造用中間体ならびにその化合物含有の医薬組成物
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
CA2093823A1 (en) * 1990-10-12 1992-04-13 Steven M. Bromidge 1,2,5,6-tetrahydropyridine oxime derivatives
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
ZA937382B (en) * 1992-10-06 1994-04-29 Warner Lambert Co Novel composition for peroral therapy of cognitionimpairment and a process therefor
AU5297693A (en) * 1992-10-06 1994-04-26 Warner-Lambert Company Stabilized compositions containing 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxyaldehyde-o-meth yl-oxime
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5731314A (en) * 1995-01-06 1998-03-24 Bencherif; Merouane Pharamceutical compositions for prevention and treatment of tourette's syndrome
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
US6455648B1 (en) 1999-12-29 2002-09-24 Chevron Phillips Chemical Company Lp Olefin production
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2392258B1 (de) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-Informatiksystem
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
US9877500B2 (en) * 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
EP2398500B1 (de) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Arzneiabgabesystem auf glutathion-basis
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CH704993A1 (fr) 2011-05-20 2012-11-30 Bacab S A Câble électrique.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
IE870497L (en) 1987-08-27
NO870771D0 (no) 1987-02-25
DK98787A (da) 1987-08-28
ATE76066T1 (de) 1992-05-15
DK167803B1 (da) 1993-12-20
NO870771L (no) 1987-08-28
GR3004845T3 (de) 1993-04-28
HU198018B (en) 1989-07-28
EP0239445B1 (de) 1992-05-13
PT84366B (pt) 1989-10-04
AU6927987A (en) 1987-09-03
JPS62252767A (ja) 1987-11-04
CA1327803C (en) 1994-03-15
US5391754A (en) 1995-02-21
NZ219416A (en) 1989-04-26
HUT44497A (en) 1988-03-28
ES2032456T3 (es) 1993-02-16
HK29797A (en) 1997-03-21
EP0239445A2 (de) 1987-09-30
DE3778951D1 (de) 1992-06-17
BG61120B2 (bg) 1996-11-29
IE59095B1 (en) 1994-01-12
US5219872A (en) 1993-06-15
FI87199C (fi) 1992-12-10
FI87199B (fi) 1992-08-31
AU588972B2 (en) 1989-09-28
EP0239445A3 (en) 1989-01-18
FI870842L (fi) 1987-08-28
KR950005197B1 (ko) 1995-05-19
IL81610A0 (en) 1987-09-16
DK98787D0 (da) 1987-02-26
NO172180B (no) 1993-03-08
JPH07599B2 (ja) 1995-01-11
IL81610A (en) 1990-12-23
FI870842A0 (fi) 1987-02-26
US5532375A (en) 1996-07-02
PT84366A (en) 1987-03-01
KR870007890A (ko) 1987-09-22

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