NO178660C - Analogifremgangsmåte for fremstilling av N-aryl-piperazinalkanamidforbindelser - Google Patents
Analogifremgangsmåte for fremstilling av N-aryl-piperazinalkanamidforbindelserInfo
- Publication number
- NO178660C NO178660C NO881407A NO881407A NO178660C NO 178660 C NO178660 C NO 178660C NO 881407 A NO881407 A NO 881407A NO 881407 A NO881407 A NO 881407A NO 178660 C NO178660 C NO 178660C
- Authority
- NO
- Norway
- Prior art keywords
- 6alkyl
- aminocarbonyl
- optionally substituted
- piperazine
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Photolithography (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3412987A | 1987-04-01 | 1987-04-01 |
Publications (4)
Publication Number | Publication Date |
---|---|
NO881407D0 NO881407D0 (no) | 1988-03-29 |
NO881407L NO881407L (no) | 1988-10-03 |
NO178660B NO178660B (no) | 1996-01-29 |
NO178660C true NO178660C (no) | 1996-05-08 |
Family
ID=21874492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO881407A NO178660C (no) | 1987-04-01 | 1988-03-29 | Analogifremgangsmåte for fremstilling av N-aryl-piperazinalkanamidforbindelser |
Country Status (21)
Country | Link |
---|---|
EP (2) | EP0727421B1 (ja) |
JP (1) | JP2574377B2 (ja) |
KR (1) | KR960016539B1 (ja) |
AT (2) | ATE207474T1 (ja) |
AU (1) | AU609790B2 (ja) |
CA (1) | CA1315790C (ja) |
DE (2) | DE3855520T2 (ja) |
DK (1) | DK174878B1 (ja) |
ES (2) | ES2091183T3 (ja) |
FI (1) | FI97617C (ja) |
GR (1) | GR3020983T3 (ja) |
HK (1) | HK1006020A1 (ja) |
HU (2) | HUT57740A (ja) |
IE (1) | IE81057B1 (ja) |
IL (1) | IL85919A (ja) |
NO (1) | NO178660C (ja) |
NZ (1) | NZ223847A (ja) |
PH (1) | PH25507A (ja) |
PT (1) | PT87118B (ja) |
RU (1) | RU2014328C1 (ja) |
ZA (1) | ZA882352B (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2173883T3 (es) * | 1989-11-22 | 2002-11-01 | Janssen Pharmaceutica Nv | Utilizacion de derivados de piperacina-acetamida contra los daños de reperfusion. |
US5840896A (en) * | 1989-11-22 | 1998-11-24 | Janssen Pharmaceutica, N.V. | Method of preventing or limiting reperfusion damage |
JP2660086B2 (ja) * | 1990-07-03 | 1997-10-08 | 明治製菓株式会社 | 脳及び心機能障害改善剤 |
US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
DK0582164T3 (da) * | 1992-07-31 | 1999-08-23 | Bristol Myers Squibb Co | Adenosin-genoptagelsesinhiberende derivater af diphenyloxazoler, -thiazoler og -imidazoler |
SE9202266D0 (sv) * | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel piperazine carboxamides |
JPH09512028A (ja) * | 1994-04-20 | 1997-12-02 | ロンザ アーゲー | 2−ピペラジンカルボン酸誘導体の製造方法 |
EP0870502A3 (en) * | 1997-04-10 | 2001-04-04 | Kyowa Hakko Kogyo Co., Ltd. | Use of adenosine uptake inhibitors for the manufacture of a medicament for the treatment of pancreatitis |
KR20010013387A (ko) * | 1997-06-16 | 2001-02-26 | 디르크 반테 | 통증을 치료하기 위한 드라플라진-유사체의 용도 |
UA89503C2 (uk) * | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Заміщені похідні аніліну |
US7598249B2 (en) | 2004-12-30 | 2009-10-06 | Janssen Pharmaceutica N.V. | Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase |
UA108233C2 (uk) | 2010-05-03 | 2015-04-10 | Модулятори активності гідролази амідів жирних кислот | |
CN110511220B (zh) * | 2018-05-22 | 2022-04-01 | 上海挚盟医药科技有限公司 | 作为钾通道调节剂的对二氨基苯衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1795375A1 (de) * | 1968-09-21 | 1972-01-05 | Boehringer Mannheim Gmbh | Basische AEther und Verfahren zur Herstellung derselben |
US4766125A (en) * | 1981-06-23 | 1988-08-23 | Janssen Pharmaceutica N.V. | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia |
-
1988
- 1988-03-10 NZ NZ223847A patent/NZ223847A/xx unknown
- 1988-03-16 CA CA000561610A patent/CA1315790C/en not_active Expired - Lifetime
- 1988-03-29 EP EP96200236A patent/EP0727421B1/en not_active Expired - Lifetime
- 1988-03-29 AU AU13847/88A patent/AU609790B2/en not_active Expired
- 1988-03-29 ES ES88200587T patent/ES2091183T3/es not_active Expired - Lifetime
- 1988-03-29 AT AT96200236T patent/ATE207474T1/de not_active IP Right Cessation
- 1988-03-29 NO NO881407A patent/NO178660C/no not_active IP Right Cessation
- 1988-03-29 DE DE3855520T patent/DE3855520T2/de not_active Expired - Lifetime
- 1988-03-29 AT AT88200587T patent/ATE142627T1/de not_active IP Right Cessation
- 1988-03-29 EP EP88200587A patent/EP0285219B1/en not_active Expired - Lifetime
- 1988-03-29 ES ES96200236T patent/ES2167510T3/es not_active Expired - Lifetime
- 1988-03-29 DE DE3856501T patent/DE3856501T2/de not_active Expired - Lifetime
- 1988-03-30 DK DK198801797A patent/DK174878B1/da not_active IP Right Cessation
- 1988-03-30 PT PT87118A patent/PT87118B/pt not_active IP Right Cessation
- 1988-03-30 IL IL85919A patent/IL85919A/xx not_active IP Right Cessation
- 1988-03-30 PH PH36714A patent/PH25507A/en unknown
- 1988-03-30 KR KR1019880003493A patent/KR960016539B1/ko not_active IP Right Cessation
- 1988-03-31 IE IE98988A patent/IE81057B1/en not_active IP Right Cessation
- 1988-03-31 HU HU881601A patent/HUT57740A/hu unknown
- 1988-03-31 RU SU884355523A patent/RU2014328C1/ru active
- 1988-03-31 ZA ZA882352A patent/ZA882352B/xx unknown
- 1988-03-31 FI FI881525A patent/FI97617C/fi not_active IP Right Cessation
- 1988-03-31 JP JP63076629A patent/JP2574377B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-20 HU HU95P/P00287P patent/HU211129A9/hu unknown
-
1996
- 1996-09-12 GR GR960402273T patent/GR3020983T3/el unknown
-
1998
- 1998-06-11 HK HK98105168A patent/HK1006020A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |