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NO166127C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner.

Info

Publication number
NO166127C
NO166127C NO863978A NO863978A NO166127C NO 166127 C NO166127 C NO 166127C NO 863978 A NO863978 A NO 863978A NO 863978 A NO863978 A NO 863978A NO 166127 C NO166127 C NO 166127C
Authority
NO
Norway
Prior art keywords
piperidines
preparation
therapeutically active
substituted diphenyl
analogy procedure
Prior art date
Application number
NO863978A
Other languages
English (en)
Other versions
NO863978L (no
NO166127B (no
NO863978D0 (no
Inventor
John Guilfoyle Mullin
Joseph Triscari
Richard Wightman Kierstead
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO863978D0 publication Critical patent/NO863978D0/no
Publication of NO863978L publication Critical patent/NO863978L/no
Publication of NO166127B publication Critical patent/NO166127B/no
Publication of NO166127C publication Critical patent/NO166127C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO863978A 1985-10-07 1986-10-06 Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner. NO166127C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/785,113 US4632925A (en) 1985-10-07 1985-10-07 N-substituted diphenylpiperidines and antiobesity use thereof

Publications (4)

Publication Number Publication Date
NO863978D0 NO863978D0 (no) 1986-10-06
NO863978L NO863978L (no) 1987-04-08
NO166127B NO166127B (no) 1991-02-25
NO166127C true NO166127C (no) 1991-06-05

Family

ID=25134481

Family Applications (1)

Application Number Title Priority Date Filing Date
NO863978A NO166127C (no) 1985-10-07 1986-10-06 Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner.

Country Status (23)

Country Link
US (1) US4632925A (no)
EP (1) EP0221376B1 (no)
JP (1) JPH0633254B2 (no)
KR (1) KR870003984A (no)
AR (1) AR241422A1 (no)
AT (1) ATE53997T1 (no)
AU (1) AU593844B2 (no)
CA (1) CA1281326C (no)
DE (1) DE3672134D1 (no)
DK (1) DK168291B1 (no)
ES (1) ES2005074A6 (no)
FI (1) FI85020C (no)
GR (1) GR862513B (no)
HU (1) HU196200B (no)
IE (1) IE59434B1 (no)
IL (1) IL80232A0 (no)
MC (1) MC1769A1 (no)
NO (1) NO166127C (no)
NZ (1) NZ217798A (no)
PH (1) PH24167A (no)
PT (1) PT83495B (no)
SG (1) SG17593G (no)
ZA (1) ZA867375B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78939A (en) * 1986-01-17 1990-04-29 Robins Co Inc A H Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
WO1992006971A1 (en) * 1990-10-10 1992-04-30 Schering Corporation Pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof
DK0635012T3 (da) * 1992-03-27 1996-08-19 Schering Corp Bis-aryl-carbinolderivater uden broer, præparater indeholdende disse og fremgangsmåder til anvendelse af disse
US6030987A (en) * 1996-05-17 2000-02-29 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6184234B1 (en) * 1994-03-01 2001-02-06 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US5639763A (en) * 1994-03-01 1997-06-17 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
AU5753696A (en) * 1995-05-19 1996-11-29 Fmc Corporation Insecticidal n-(substituted arylmethyl)-4-{bis(substituted p henyl or pyridyl)methyl}piperidines
US6407116B1 (en) 1997-09-16 2002-06-18 Takeda Chemical Industries, Inc. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
US20100064413A1 (en) * 2008-03-14 2010-03-18 Simply Weights, LLC Exercise clothing and accessories
WO2009132978A1 (en) 2008-04-29 2009-11-05 F. Hoffmann-La Roche Ag 4-dimethylaminobutyric acid derivatives
EP2280935B1 (en) * 2008-04-29 2014-10-15 F. Hoffmann-La Roche AG 4-trimethylammonio-butyrates as cpt2 inhibitors
JP7269943B2 (ja) 2018-01-08 2023-05-09 エフ. ホフマン-ラ ロシュ アーゲー Magl阻害剤としてのオクタヒドロピリド[1,2-アルファ]ピラジン
CR20230115A (es) 2020-09-03 2023-04-11 Hoffmann La Roche Compuestos heterocíclicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076717A (en) * 1971-12-15 1978-02-28 G. D. Searle & Co. Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines

Also Published As

Publication number Publication date
DK168291B1 (da) 1994-03-07
PT83495A (en) 1986-11-01
FI864051A0 (fi) 1986-10-07
NO863978L (no) 1987-04-08
HUT41768A (en) 1987-05-28
IE862636L (en) 1987-04-07
DK475286A (da) 1987-04-08
NO166127B (no) 1991-02-25
EP0221376A2 (de) 1987-05-13
FI85020B (fi) 1991-11-15
ATE53997T1 (de) 1990-07-15
IL80232A0 (en) 1987-01-30
DE3672134D1 (de) 1990-07-26
NO863978D0 (no) 1986-10-06
US4632925A (en) 1986-12-30
DK475286D0 (da) 1986-10-03
EP0221376A3 (en) 1987-09-02
PH24167A (en) 1990-03-22
HU196200B (en) 1988-10-28
PT83495B (pt) 1989-05-31
ES2005074A6 (es) 1989-03-01
SG17593G (en) 1993-05-21
JPS6287585A (ja) 1987-04-22
NZ217798A (en) 1989-10-27
CA1281326C (en) 1991-03-12
IE59434B1 (en) 1994-02-23
ZA867375B (en) 1987-05-27
FI85020C (fi) 1992-02-25
JPH0633254B2 (ja) 1994-05-02
FI864051A (fi) 1987-04-08
AR241422A1 (es) 1992-07-31
GR862513B (en) 1987-02-09
AU593844B2 (en) 1990-02-22
KR870003984A (ko) 1987-05-06
EP0221376B1 (de) 1990-06-20
MC1769A1 (fr) 1987-07-17
AU6350186A (en) 1987-04-09

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