NL7513833A - METHOD FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZODIAZEPINS, METHOD FOR THE PREPARATION OF A MEDICINAL PRODUCT ACTING ON THE CENTRAL NERVOUS SYSTEM AND THE LIKE MEDICINAL PRODUCT. - Google Patents

METHOD FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZODIAZEPINS, METHOD FOR THE PREPARATION OF A MEDICINAL PRODUCT ACTING ON THE CENTRAL NERVOUS SYSTEM AND THE LIKE MEDICINAL PRODUCT.

Info

Publication number: NL7513833A
Authority: NL; Netherlands
Prior art keywords: preparation; medicinal product; benzodiazepins; nervous system; central nervous
Prior art date: 1974-11-26

Application number

NL7513833A

Other languages

Dutch (nl)

Other versions

NL186088C (en

NL186088B (en

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-11-26

Filing date

1975-11-26

Publication date

1976-05-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL7513833(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1975-11-26 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1976-05-31 Publication of NL7513833A publication Critical patent/NL7513833A/en

1990-04-17 Publication of NL186088B publication Critical patent/NL186088B/en

1990-09-17 Application granted granted Critical

1990-09-17 Publication of NL186088C publication Critical patent/NL186088C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NLAANVRAGE7513833,A 1974-11-26 1975-11-26 PROCESS FOR PREPARING A MEDICINAL PRODUCT, WITH AN EFFECT ON THE CENTRAL NERVOUS SYSTEM CONTAINING AT LEAST ONE DERIVATIVE OF AN AMINO-THIENOBENZO-N-HETEROSOVEN COMPOUND, AND PROCESS FOR THE PREPARATION OF THIS PRODUCT NL186088C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB51240/74A GB1533235A (en)	1974-11-26	1974-11-26	Benzodiazepine derivatives

Publications (3)

Publication Number	Publication Date
NL7513833A true NL7513833A (en)	1976-05-31
NL186088B NL186088B (en)	1990-04-17
NL186088C NL186088C (en)	1990-09-17

Family

ID=10459213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7513833,A NL186088C (en)	1974-11-26	1975-11-26	PROCESS FOR PREPARING A MEDICINAL PRODUCT, WITH AN EFFECT ON THE CENTRAL NERVOUS SYSTEM CONTAINING AT LEAST ONE DERIVATIVE OF AN AMINO-THIENOBENZO-N-HETEROSOVEN COMPOUND, AND PROCESS FOR THE PREPARATION OF THIS PRODUCT

Country Status (30)

Country	Link
JP (1)	JPS6044314B2 (en)
AR (1)	AR221203A1 (en)
AT (1)	AT351547B (en)
AU (1)	AU506340B2 (en)
BE (1)	BE835932A (en)
BG (1)	BG29573A3 (en)
CA (1)	CA1075687A (en)
CH (2)	CH613454A5 (en)
CS (1)	CS236753B2 (en)
DD (1)	DD123343A5 (en)
DE (1)	DE2552403C2 (en)
DK (1)	DK146887C (en)
ES (1)	ES443011A1 (en)
FR (1)	FR2292479A1 (en)
GB (1)	GB1533235A (en)
HK (1)	HK58681A (en)
HU (1)	HU172493B (en)
IE (1)	IE42564B1 (en)
IL (1)	IL48502A (en)
KE (1)	KE3163A (en)
MY (1)	MY8200149A (en)
NL (1)	NL186088C (en)
NZ (1)	NZ179335A (en)
PH (2)	PH11669A (en)
PL (1)	PL100135B1 (en)
RO (1)	RO69912A (en)
SE (2)	SE421209B (en)
SU (2)	SU629879A3 (en)
YU (1)	YU298375A (en)
ZA (1)	ZA757344B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL62792A (en) *	1980-05-07	1985-02-28	Byk Gulden Lomberg Chem Fab	Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) *	1988-08-11	1988-09-14	Lilly Industries Ltd	Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en)	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
ATE198891T1 (en) *	1992-05-29	2001-02-15	Lilly Co Eli	THIENOBENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
US6043358A (en)	1995-11-01	2000-03-28	Merck & Co., Inc.	Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
EP0861238A4 (en) *	1995-11-01	2000-03-01	Merck & Co Inc	Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
NZ503484A (en)	1997-09-02	2001-10-26	Welfide Corp	Optionally benzo fused thieno[2,3-b]benzoxazepine, thieno[2,3-b]benzodiazepine or thieno[2,3-b]benzothiaxazepine derivatives
PL199016B1 (en) *	2002-06-20	2008-08-29	Adamed Sp Z Oo	Method of manufacture of alanzapine, new derivative of n-demethyl olanzapine and method of manufacture of new derivative of n-demethyl olanzapine
SI21270A (en)	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Crystal forms of olanzapine and procedures for their preparation
DE10301923B3 (en) *	2003-01-17	2004-09-16	Krka Tovarna Zdravil, D.D.	Process and intermediates for the production of olanzapine
EP1720885A1 (en) *	2004-01-27	2006-11-15	Synthon B.V.	A process for making olanzapine in a polymorph form i
AR048272A1 (en)	2004-03-18	2006-04-12	Lek Pharmaceuticals	SYNTHESIS OF 2 METHYL - 4- (4- METHYL -1- PIPERAZINIL) - 10 H- TIENO (2,3-B) (1,5) BENZODIAZEPIN AND ITS SALTS, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND ITS USE IN THE MANUFACTURE OF MEDICINES FOR THE TREATMENT OF MENTAL DISEASES.
KR101216984B1 (en) *	2004-06-30	2013-01-02	아더시스 인코포레이티드	Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en)	2009-07-20	2011-03-09	LEK Pharmaceuticals d.d.	Process for the purification of olanzapine

1974
- 1974-11-25 SU SU742191705A patent/SU629879A3/en active
- 1974-11-26 GB GB51240/74A patent/GB1533235A/en not_active Expired
1975
- 1975-11-20 DK DK524175A patent/DK146887C/en active
- 1975-11-20 IL IL48502A patent/IL48502A/en unknown
- 1975-11-20 CA CA240,082A patent/CA1075687A/en not_active Expired
- 1975-11-21 PH PH17788A patent/PH11669A/en unknown
- 1975-11-21 AU AU86858/75A patent/AU506340B2/en not_active Expired
- 1975-11-22 DE DE2552403A patent/DE2552403C2/en not_active Expired
- 1975-11-24 CH CH1517275A patent/CH613454A5/en not_active IP Right Cessation
- 1975-11-24 NZ NZ179335A patent/NZ179335A/en unknown
- 1975-11-24 CH CH604478A patent/CH613455A5/en not_active IP Right Cessation
- 1975-11-24 ZA ZA757344A patent/ZA757344B/en unknown
- 1975-11-24 SE SE7513185A patent/SE421209B/en not_active IP Right Cessation
- 1975-11-25 JP JP50141080A patent/JPS6044314B2/en not_active Expired
- 1975-11-25 AR AR261340A patent/AR221203A1/en active
- 1975-11-25 DD DD189666A patent/DD123343A5/xx unknown
- 1975-11-25 IE IE2565/75A patent/IE42564B1/en unknown
- 1975-11-25 FR FR7535900A patent/FR2292479A1/en active Granted
- 1975-11-25 RO RO7584018A patent/RO69912A/en unknown
- 1975-11-25 BE BE6045266A patent/BE835932A/en not_active IP Right Cessation
- 1975-11-25 YU YU02983/75A patent/YU298375A/en unknown
- 1975-11-26 HU HU75LI00000284A patent/HU172493B/en unknown
- 1975-11-26 CS CS757991A patent/CS236753B2/en unknown
- 1975-11-26 AT AT898275A patent/AT351547B/en not_active IP Right Cessation
- 1975-11-26 BG BG031601A patent/BG29573A3/en unknown
- 1975-11-26 PL PL1975184991A patent/PL100135B1/en unknown
- 1975-11-26 NL NLAANVRAGE7513833,A patent/NL186088C/en not_active IP Right Cessation
- 1975-11-26 ES ES443011A patent/ES443011A1/en not_active Expired
1976
- 1976-10-07 SU SU762406250A patent/SU626702A3/en active
1977
- 1977-02-22 PH PH19480A patent/PH24534A/en unknown
1978
- 1978-11-27 SE SE7812194A patent/SE429045B/en not_active IP Right Cessation
1981
- 1981-09-24 KE KE3163A patent/KE3163A/en unknown
- 1981-11-26 HK HK586/81A patent/HK58681A/en unknown
1982
- 1982-12-30 MY MY149/82A patent/MY8200149A/en unknown

Also Published As

Publication number	Publication date
CS236753B2 (en)	1985-05-15
DK146887B (en)	1984-01-30
DD123343A5 (en)	1976-12-12
IL48502A0 (en)	1976-01-30
PL100135B1 (en)	1978-09-30
PH11669A (en)	1978-05-19
FR2292479B1 (en)	1978-07-28
CA1075687A (en)	1980-04-15
BE835932A (en)	1976-05-25
DK524175A (en)	1976-05-27
AU506340B2 (en)	1979-12-20
DK146887C (en)	1984-07-09
SE421209B (en)	1981-12-07
RO69912A (en)	1980-08-15
SE429045B (en)	1983-08-08
MY8200149A (en)	1982-12-31
IE42564B1 (en)	1980-09-10
GB1533235A (en)	1978-11-22
NL186088C (en)	1990-09-17
HU172493B (en)	1978-09-28
JPS5176296A (en)	1976-07-01
ES443011A1 (en)	1977-07-01
NZ179335A (en)	1978-11-13
ATA898275A (en)	1979-01-15
IL48502A (en)	1980-01-31
YU298375A (en)	1982-10-31
IE42564L (en)	1976-05-26
HK58681A (en)	1981-12-04
AT351547B (en)	1979-07-25
DE2552403A1 (en)	1976-08-12
SU629879A3 (en)	1978-10-25
SE7513185L (en)	1976-05-27
AU8685875A (en)	1977-05-26
CH613455A5 (en)	1979-09-28
NL186088B (en)	1990-04-17
KE3163A (en)	1981-10-16
AR221203A1 (en)	1981-01-15
PH24534A (en)	1990-08-03
ZA757344B (en)	1976-11-24
SE7812194L (en)	1978-11-27
JPS6044314B2 (en)	1985-10-02
SU626702A3 (en)	1978-09-30
CH613454A5 (en)	1979-09-28
BG29573A3 (en)	1980-12-12
DE2552403C2 (en)	1986-06-19
FR2292479A1 (en)	1976-06-25

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Legal Events

Date	Code	Title	Description
1982-10-01	BA	A request for search or an international-type search has been filed
1983-01-03	BB	A search report has been drawn up
1983-05-02	BC	A request for examination has been filed
1985-01-01	A85	Still pending on 85-01-01
1990-12-17	BK	Erratum	Free format text: CORRECTION TO PAMPHLET
1996-02-01	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 951126