NL2000284A1 - Pyrazine-derivaten. - Google Patents

Pyrazine-derivaten.

Info

Publication number: NL2000284A1
Authority: NL; Netherlands
Prior art keywords: pyrazine derivatives; pyrazine; derivatives
Prior art date: 2005-11-04

Application number

NL2000284A

Other languages

English (en)

Other versions

NL2000284C2 (nl

Inventor

Karl Richard Gibson

Cedric Poinsard

Melanie Susanne Glossop

Stephen Mark Denton

Mark Ian Kemp

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-04

Filing date

2006-10-20

Publication date

2007-05-07

2006-10-20 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

2007-05-07 Publication of NL2000284A1 publication Critical patent/NL2000284A1/nl

2007-09-28 Application granted granted Critical

2007-09-28 Publication of NL2000284C2 publication Critical patent/NL2000284C2/nl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Medicines Containing Plant Substances (AREA)

NL2000284A 2005-11-04 2006-10-20 Pyrazine-derivaten. NL2000284C2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73366205P	2005-11-04	2005-11-04
US73366205		2005-11-04

Publications (2)

Publication Number	Publication Date
NL2000284A1 true NL2000284A1 (nl)	2007-05-07
NL2000284C2 NL2000284C2 (nl)	2007-09-28

Family

ID=37890558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL2000284A NL2000284C2 (nl)	2005-11-04	2006-10-20	Pyrazine-derivaten.

Country Status (27)

Country	Link
US (1)	US7572797B2 (nl)
EP (1)	EP1945630B1 (nl)
JP (1)	JP2009514937A (nl)
KR (1)	KR20080066073A (nl)
CN (1)	CN101356169A (nl)
AP (1)	AP2008004468A0 (nl)
AR (1)	AR057855A1 (nl)
AT (1)	ATE525372T1 (nl)
AU (1)	AU2006310215A1 (nl)
BR (1)	BRPI0618129A2 (nl)
CA (1)	CA2624621C (nl)
CR (1)	CR9954A (nl)
DO (1)	DOP2006000243A (nl)
EA (1)	EA200801011A1 (nl)
EC (1)	ECSP088412A (nl)
ES (1)	ES2371932T3 (nl)
GT (1)	GT200600475A (nl)
IL (1)	IL191059A0 (nl)
MA (1)	MA29926B1 (nl)
NL (1)	NL2000284C2 (nl)
NO (1)	NO20082496L (nl)
PE (1)	PE20070715A1 (nl)
TN (1)	TNSN08196A1 (nl)
TW (1)	TW200804353A (nl)
UY (1)	UY29893A1 (nl)
WO (1)	WO2007052123A2 (nl)
ZA (1)	ZA200803671B (nl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2200184T7 (es)	1996-07-24	2015-02-10	Warner-Lambert Company Llc	Isobutilgaba y sus derivados para el tratamiento del dolor
EP1741708A1 (en) *	2005-06-28	2007-01-10	Sanofi-Aventis Deutschland GmbH	Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals
GB2431927B (en)	2005-11-04	2010-03-17	Amira Pharmaceuticals Inc	5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en)	2005-11-04	2013-03-19	Panmira Pharmaceuticals, Llc	5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en)	2005-11-04	2011-07-12	Amira Pharmaceuticals, Inc.	5-lipdxygenase-activating protein (FLAP) inhibitors
US20100227872A1 (en) *	2007-05-03	2010-09-09	Mark Ian Kemp	Pyrazine derivatives
NZ581614A (en)	2007-05-03	2011-06-30	Pfizer Ltd	2-pyridine carboxamide derivatives as sodium channel modulators
US8614255B2 (en) *	2007-08-21	2013-12-24	Civitas Therapeutics, Inc.	Pulmonary pharmaceutical formulations
EP2231280B1 (en)	2007-12-10	2016-08-10	Novartis AG	Amiloride-like Pyrazine-carboxamides as ENaC blockers
EP2241567A4 (en)	2008-02-13	2011-11-09	Eisai R&D Man Co Ltd	Bicycloamine DERIVATIVE
US8772495B2 (en)	2008-05-23	2014-07-08	Panmira Pharmaceuticals, Llc	5-lipoxygenase-activating protein inhibitor
US8546431B2 (en)	2008-10-01	2013-10-01	Panmira Pharmaceuticals, Llc	5-lipoxygenase-activating protein (FLAP) inhibitors
US10703722B2 (en)	2010-04-27	2020-07-07	Calcimedica, Inc.	Compounds that modulate intracellular calcium
WO2013059677A1 (en) *	2011-10-19	2013-04-25	Calcimedica, Inc.	Compounds that modulate intracellular calcium
KR102090944B1 (ko) *	2012-04-25	2020-03-19	라퀄리아 파마 인코포레이티드	Ttx-s 차단제로서의 피롤로피리디논 유도체
JP6424173B2 (ja)	2013-02-04	2018-11-14	ヤンセンファーマシューティカエヌ．ベー．	Ｆｌａｐ調節因子
TWI644899B (zh)	2013-02-04	2018-12-21	健生藥品公司	Ｆｌａｐ調節劑
CA2960274A1 (en)	2014-09-10	2016-03-17	Epizyme, Inc.	Isoxazole carboxamide compounds
EA202091639A3 (ru)	2015-02-27	2021-06-30	Кальцимедика, Инк.	Лечение панкреатита
DK3331525T3 (da)	2015-08-07	2020-12-14	Calcimedica Inc	Anvendelse af CRAC-kanal-inhibitorer til behandling af slagtilfælde og traumatisk hjerneskade
GB201801128D0 (en)	2018-01-24	2018-03-07	Univ Oxford Innovation Ltd	Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MA26473A1 (fr) *	1997-03-01	2004-12-20	Glaxo Group Ltd	Composes pharmacologiquement actifs.
AU2002343557A1 (en) *	2001-11-21	2003-06-10	Pharmacia And Upjohn Company	Substituted aryl 1,4-pyrazine derivatives
US20030187026A1 (en)	2001-12-13	2003-10-02	Qun Li	Kinase inhibitors
CA2543644A1 (en) *	2003-10-27	2005-05-06	Astellas Pharma Inc.	Pyrazine derivatives and pharmaceutical use thereof
CN101084208A (zh) *	2004-10-22	2007-12-05	詹森药业有限公司	作为c－fms激酶抑制剂的芳族酰胺

2006
- 2006-10-20 NL NL2000284A patent/NL2000284C2/nl not_active IP Right Cessation
- 2006-10-23 CN CNA2006800504914A patent/CN101356169A/zh active Pending
- 2006-10-23 JP JP2008539517A patent/JP2009514937A/ja not_active Ceased
- 2006-10-23 AT AT06809149T patent/ATE525372T1/de not_active IP Right Cessation
- 2006-10-23 CA CA2624621A patent/CA2624621C/en not_active Expired - Fee Related
- 2006-10-23 KR KR1020087013403A patent/KR20080066073A/ko not_active Application Discontinuation
- 2006-10-23 BR BRPI0618129-5A patent/BRPI0618129A2/pt not_active IP Right Cessation
- 2006-10-23 EA EA200801011A patent/EA200801011A1/ru unknown
- 2006-10-23 WO PCT/IB2006/003055 patent/WO2007052123A2/en active Search and Examination
- 2006-10-23 AP AP2008004468A patent/AP2008004468A0/xx unknown
- 2006-10-23 EP EP06809149A patent/EP1945630B1/en not_active Not-in-force
- 2006-10-23 ES ES06809149T patent/ES2371932T3/es active Active
- 2006-10-23 AU AU2006310215A patent/AU2006310215A1/en not_active Abandoned
- 2006-11-01 UY UY29893A patent/UY29893A1/es not_active Application Discontinuation
- 2006-11-02 GT GT200600475A patent/GT200600475A/es unknown
- 2006-11-02 AR ARP060104815A patent/AR057855A1/es unknown
- 2006-11-03 TW TW095140879A patent/TW200804353A/zh unknown
- 2006-11-03 US US11/556,354 patent/US7572797B2/en not_active Expired - Fee Related
- 2006-11-03 PE PE2006001349A patent/PE20070715A1/es not_active Application Discontinuation
- 2006-11-03 DO DO2006000243A patent/DOP2006000243A/es unknown
2008
- 2008-04-25 ZA ZA200803671A patent/ZA200803671B/xx unknown
- 2008-04-27 IL IL191059A patent/IL191059A0/en unknown
- 2008-04-29 EC EC2008008412A patent/ECSP088412A/es unknown
- 2008-05-02 MA MA30893A patent/MA29926B1/fr unknown
- 2008-05-02 TN TNP2008000196A patent/TNSN08196A1/fr unknown
- 2008-05-07 CR CR9954A patent/CR9954A/es not_active Application Discontinuation
- 2008-06-04 NO NO20082496A patent/NO20082496L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2007052123A3 (en)	2007-07-12
AU2006310215A1 (en)	2007-05-10
ZA200803671B (en)	2009-03-25
NL2000284C2 (nl)	2007-09-28
ES2371932T3 (es)	2012-01-11
CA2624621C (en)	2010-11-30
AP2008004468A0 (en)	2008-06-30
EA200801011A1 (ru)	2009-02-27
KR20080066073A (ko)	2008-07-15
IL191059A0 (en)	2008-12-29
UY29893A1 (es)	2007-06-29
CR9954A (es)	2008-05-28
US7572797B2 (en)	2009-08-11
GT200600475A (es)	2007-07-06
AR057855A1 (es)	2007-12-19
PE20070715A1 (es)	2007-08-11
CA2624621A1 (en)	2007-05-10
TNSN08196A1 (fr)	2009-10-30
MA29926B1 (fr)	2008-11-03
US20070105872A1 (en)	2007-05-10
JP2009514937A (ja)	2009-04-09
CN101356169A (zh)	2009-01-28
DOP2006000243A (es)	2007-05-31
EP1945630B1 (en)	2011-09-21
BRPI0618129A2 (pt)	2011-08-16
EP1945630A2 (en)	2008-07-23
ATE525372T1 (de)	2011-10-15
WO2007052123A2 (en)	2007-05-10
NO20082496L (no)	2008-07-24
ECSP088412A (es)	2008-05-30
TW200804353A (en)	2008-01-16

Publication	Publication Date	Title
NL300935I2 (nl)	2018-10-25	guselkumab.
NL2000284A1 (nl)	2007-05-07	Pyrazine-derivaten.
NL2000323A1 (nl)	2007-06-21	Pyrimidine-derivaten.
NL1031741A1 (nl)	2006-11-07	Purinederivaten.
NL1031385A1 (nl)	2006-09-20	Gesubstitueerde sulfonylaminoarylmethylcyclopropaancarbonamideverbindingen.
NL1031218A1 (nl)	2006-08-23	Oxyindoolderivaten.
ATE520670T1 (de)	2011-09-15	Pyridazinderivate
NL1031335A1 (nl)	2006-09-12	Gesubstitueerde N-sulfonylaminofenylethyl-2-fenoxyaceetamideverbindingen.
DE602006010581D1 (de)	2009-12-31	4-phenyl-6-substituierte pyrimidin-2-carbonitrilderivate
ATE485294T1 (de)	2010-11-15	Azaindol-2-carboxamid-derivate
NO20051199D0 (no)	2005-03-07	Rorhandteringsutstyr.
ATE527255T1 (de)	2011-10-15	Aryl-isoxazol-4-yl-imidazol-derivate
DK1971588T3 (da)	2012-10-22	Tiglien-3-onderivater
FR2892275B1 (fr)	2009-11-20	Poudrier.
NL1032046A1 (nl)	2007-01-02	Prostaglandinederivaten.
NL2000937A1 (nl)	2008-01-11	Piperidinederivaten.
NO20053362L (no)	2007-01-12	Syklofuge.
ATE541837T1 (de)	2012-02-15	Oxaphenanthren-derivate
ITMI20050051A1 (it)	2006-07-19	Fotodiodio organico di poli-9,9-diottil-fluorene
FR2889804B1 (fr)	2008-05-02	Lit medicalise surbaisse.
DE602006019209D1 (de)	2011-02-10	Fluoroalkylpyrrolidin-derivate
ITRN20050016U1 (it)	2007-06-23	Struttura combinata.
ES1060970Y (es)	2006-03-16	Llavero-monedero.
ES1059785Y (es)	2005-09-16	Caja-asiento.
ES1059992Y (es)	2005-10-16	Marco-estuche.

Legal Events

Date	Code	Title	Description
2007-07-02	AD1A	A request for search or an international type search has been filed
2007-10-01	RD2N	Patents in respect of which a decision has been taken or a report has been made (novelty report)	Effective date: 20070727
2007-12-03	PD2B	A search report has been drawn up
2010-05-26	V1	Lapsed because of non-payment of the annual fee	Effective date: 20100501