MXPA05013225A - Derivados de 1-aril-4-(ariloxicarbonil)-piperazina para uso como inhibidores de la lipasa sensible a hormonas. - Google Patents
Derivados de 1-aril-4-(ariloxicarbonil)-piperazina para uso como inhibidores de la lipasa sensible a hormonas.Info
- Publication number
- MXPA05013225A MXPA05013225A MXPA05013225A MXPA05013225A MXPA05013225A MX PA05013225 A MXPA05013225 A MX PA05013225A MX PA05013225 A MXPA05013225 A MX PA05013225A MX PA05013225 A MXPA05013225 A MX PA05013225A MX PA05013225 A MXPA05013225 A MX PA05013225A
- Authority
- MX
- Mexico
- Prior art keywords
- aryloxycarbonyl
- inhibitors
- aryl
- sensitive lipase
- hormone sensitive
- Prior art date
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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Abstract
La presente invencion se refiere a piperazinas novedosas de la formula (I), a composiciones farmaceuticas que las comprenden y al uso de las mismas en el tratamiento y/o prevencion de enfermedades y trastornos relacionados con la lipasa sensible a hormonas. Mas particularmente, los compuestos son utiles para el tratamiento y/o prevencion de enfermedades y trastornos en los cuales es benefica la modulacion de la lipolisis, tal como la lipolisis disminuida.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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DKPA200300876 | 2003-06-12 | ||
US47845103P | 2003-06-13 | 2003-06-13 | |
PCT/DK2004/000396 WO2004111007A1 (en) | 2003-06-12 | 2004-06-10 | 1-aryl-4-(aryloxycarbonyl)-piperazine derivatives for use as inhibitors of hormone sensitive lipase |
Publications (1)
Publication Number | Publication Date |
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MXPA05013225A true MXPA05013225A (es) | 2006-03-09 |
Family
ID=33553687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05013225A MXPA05013225A (es) | 2003-06-12 | 2004-06-10 | Derivados de 1-aril-4-(ariloxicarbonil)-piperazina para uso como inhibidores de la lipasa sensible a hormonas. |
Country Status (10)
Country | Link |
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US (1) | US20060160819A1 (es) |
EP (1) | EP1636189A1 (es) |
JP (1) | JP2006527211A (es) |
KR (1) | KR20060015739A (es) |
CN (1) | CN1798735A (es) |
AU (1) | AU2004247320A1 (es) |
BR (1) | BRPI0410657A (es) |
CA (1) | CA2526518A1 (es) |
MX (1) | MXPA05013225A (es) |
WO (1) | WO2004111007A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7269708B2 (en) * | 2004-04-20 | 2007-09-11 | Rambus Inc. | Memory controller for non-homogenous memory system |
RU2376289C2 (ru) | 2005-02-17 | 2009-12-20 | Астеллас Фарма Инк. | Пиридильное неароматическое азотсодержащее гетероцикло-1-карбоксилатное производное |
EP2178821A2 (en) * | 2007-07-12 | 2010-04-28 | Deviris Inc. | Hormone sensitive lipase modulators and methods of use |
TW201044234A (en) * | 2009-06-08 | 2010-12-16 | Chunghwa Picture Tubes Ltd | Method of scanning touch panel |
SI2888243T1 (sl) * | 2012-08-23 | 2016-11-30 | Suven Life Sciences Limited Serene Chambers | Akrilamidne spojine kot histamin H3 receptor ligandi |
SG11201503959VA (en) | 2012-11-20 | 2015-06-29 | Merial Inc | Anthelmintic compounds and compositions and method of using thereof |
US11597715B2 (en) | 2018-01-11 | 2023-03-07 | Centaurus Therapeutics | Inhibitors of dihydroceramide desaturase for treating disease |
US20220185796A1 (en) * | 2019-03-27 | 2022-06-16 | St. Jude Children's Research Hospital | Small molecule modulators of pank |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
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YU71101A (sh) * | 1999-04-01 | 2004-07-15 | Pfizer Products Inc. | Aminopirimidini kao inhibitori sorbitol dehidrogenaze |
WO2001087843A1 (en) * | 2000-05-15 | 2001-11-22 | Novo Nordisk A/S | Compounds for treating disorders where a decreased level of plasma ffa is desired |
WO2003051842A2 (en) * | 2001-12-14 | 2003-06-26 | Novo Nordisk A/S | Compositions decreasing activity of hormone-sensitive lipase |
-
2004
- 2004-06-10 EP EP04736501A patent/EP1636189A1/en not_active Withdrawn
- 2004-06-10 AU AU2004247320A patent/AU2004247320A1/en not_active Abandoned
- 2004-06-10 CA CA002526518A patent/CA2526518A1/en not_active Abandoned
- 2004-06-10 WO PCT/DK2004/000396 patent/WO2004111007A1/en active Application Filing
- 2004-06-10 BR BRPI0410657-1A patent/BRPI0410657A/pt not_active IP Right Cessation
- 2004-06-10 KR KR1020057022759A patent/KR20060015739A/ko not_active Application Discontinuation
- 2004-06-10 JP JP2006515704A patent/JP2006527211A/ja not_active Withdrawn
- 2004-06-10 MX MXPA05013225A patent/MXPA05013225A/es unknown
- 2004-06-10 CN CNA2004800149542A patent/CN1798735A/zh active Pending
-
2005
- 2005-12-12 US US11/299,637 patent/US20060160819A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI0410657A (pt) | 2006-06-20 |
CN1798735A (zh) | 2006-07-05 |
KR20060015739A (ko) | 2006-02-20 |
EP1636189A1 (en) | 2006-03-22 |
US20060160819A1 (en) | 2006-07-20 |
CA2526518A1 (en) | 2004-12-23 |
WO2004111007A1 (en) | 2004-12-23 |
AU2004247320A1 (en) | 2004-12-23 |
JP2006527211A (ja) | 2006-11-30 |
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