MX360827B - Metodos para tratar la esteatohepatitis no alcoholica (nash) usando productos de cisteamina. - Google Patents
Metodos para tratar la esteatohepatitis no alcoholica (nash) usando productos de cisteamina.Info
- Publication number
- MX360827B MX360827B MX2015010032A MX2015010032A MX360827B MX 360827 B MX360827 B MX 360827B MX 2015010032 A MX2015010032 A MX 2015010032A MX 2015010032 A MX2015010032 A MX 2015010032A MX 360827 B MX360827 B MX 360827B
- Authority
- MX
- Mexico
- Prior art keywords
- nash
- alcoholic steatohepatitis
- methods
- treating non
- fatty liver
- Prior art date
Links
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 title abstract 5
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title abstract 3
- 229960003151 mercaptamine Drugs 0.000 title abstract 3
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 title abstract 3
- 208000004930 Fatty Liver Diseases 0.000 abstract 2
- 206010019708 Hepatic steatosis Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000010706 fatty liver disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La descripción se relaciona, en general, al tratamiento de desórdenes del hígado graso que comprende administrar composiciones que comprenden productos de cisteamina. La descripción proporciona la administración de composiciones de cisteamina entéricamente recubiertas para tratar desórdenes del hígado graso, tal como la enfermedad de hígado graso no alcohólica (NAFLD) y esteatohepatitis no alcohólica (NASH).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99151707P | 2007-11-30 | 2007-11-30 | |
US8539708P | 2008-07-31 | 2008-07-31 | |
PCT/US2008/085064 WO2009070781A1 (en) | 2007-11-30 | 2008-11-28 | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products |
Publications (1)
Publication Number | Publication Date |
---|---|
MX360827B true MX360827B (es) | 2018-11-16 |
Family
ID=40679016
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015010032A MX360827B (es) | 2007-11-30 | 2008-11-28 | Metodos para tratar la esteatohepatitis no alcoholica (nash) usando productos de cisteamina. |
MX2010005921A MX2010005921A (es) | 2007-11-30 | 2008-11-28 | Metodos para tratar la esteatohepatitis no alcoholica (nash) usando productos de cisteamina. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010005921A MX2010005921A (es) | 2007-11-30 | 2008-11-28 | Metodos para tratar la esteatohepatitis no alcoholica (nash) usando productos de cisteamina. |
Country Status (25)
Country | Link |
---|---|
US (5) | US7994226B2 (es) |
EP (2) | EP2214480B1 (es) |
JP (3) | JP5583022B2 (es) |
KR (1) | KR20100091219A (es) |
CN (2) | CN104825430B (es) |
AR (1) | AR069500A1 (es) |
AU (1) | AU2008329628B2 (es) |
BR (1) | BRPI0819690B8 (es) |
CA (1) | CA2706768C (es) |
CL (1) | CL2008003582A1 (es) |
CY (1) | CY1114126T1 (es) |
DK (1) | DK2214480T3 (es) |
ES (1) | ES2417179T3 (es) |
HR (1) | HRP20130590T1 (es) |
IL (2) | IL205909B (es) |
MX (2) | MX360827B (es) |
MY (1) | MY156316A (es) |
NZ (1) | NZ585732A (es) |
PL (1) | PL2214480T3 (es) |
PT (1) | PT2214480E (es) |
RU (1) | RU2498795C2 (es) |
SG (1) | SG10201403200RA (es) |
TW (2) | TWI535435B (es) |
WO (1) | WO2009070781A1 (es) |
ZA (1) | ZA201003670B (es) |
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BRPI0707277B1 (pt) | 2006-01-27 | 2021-07-13 | The Regents Of The University Of California | Composição, uso da mesma,e , formulação famacêutica |
AU2008329628B2 (en) | 2007-11-30 | 2014-06-26 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products |
JP5800368B2 (ja) * | 2010-05-19 | 2015-10-28 | 興和株式会社 | 非アルコール性脂肪性肝炎の予防及び/又は治療剤 |
BR112012031194A2 (pt) * | 2010-06-08 | 2018-05-29 | Krisani Biosciences P Ltd | derivados de cisteamina e seu uso no tratamento de ehna |
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WO2014045293A1 (en) * | 2012-09-24 | 2014-03-27 | Krisani Bioscience (P) Ltd. | Fatty acid amides with a cysteamine or an acetylated cysteamine group and uses thereof |
US20130085075A1 (en) * | 2011-06-06 | 2013-04-04 | Meso Scale Technologies, Llc | Diagnostic methods for liver disorders |
KR101974675B1 (ko) | 2011-09-16 | 2019-05-02 | 갈렉틴 테라퓨틱스, 인크. | 비알콜성 지방간염 및 비알콜성 지방간 질환의 치료를 위한 갈락토-람노갈락투로네이트 조성물 |
CA2853484C (en) | 2011-10-26 | 2018-08-21 | Seattle Children's Research Institute | Cysteamine in the treatment of fibrotic disease |
JP6411215B2 (ja) * | 2011-11-22 | 2018-10-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 虚血傷害を治療するためのシステアミンおよび/またはシスタミン |
HK1206646A1 (en) * | 2012-03-29 | 2016-01-15 | Halo Therapeutics, Llc | Dosage forms of halofuginone and methods of use |
US9763974B2 (en) | 2012-06-06 | 2017-09-19 | Galectin Therapeutics, Inc. | Galacto-rhamnogalacturonate compositions for the treatment of diseases associated with elevated inducible nitric oxide synthase |
US20140314841A1 (en) | 2013-04-19 | 2014-10-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Use of Cysteamine and Derivatives Thereof to Suppress Tumor Metastases |
TWI649100B (zh) * | 2013-06-17 | 2019-02-01 | 地平線罕見醫學製藥有限責任公司 | 延遲釋放型半胱胺珠粒調配物,以及其製備及使用方法 |
US9682123B2 (en) | 2013-12-20 | 2017-06-20 | The Trustees Of Columbia University In The City Of New York | Methods of treating metabolic disease |
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TW202247838A (zh) * | 2015-07-02 | 2022-12-16 | 美商地平線罕見醫學製藥有限責任公司 | Ado抗性半胱胺類似物及其用途 |
RU2595815C1 (ru) * | 2015-07-13 | 2016-08-27 | федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохранения Российской Федерации | Способ лечения больных неалкогольным стеатогепатитом на фоне метаболического синдрома |
US10537528B2 (en) | 2015-11-16 | 2020-01-21 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine compounds |
US10143665B2 (en) | 2015-11-17 | 2018-12-04 | Horizon Orphan Llc | Methods for storing cysteamine formulations and related methods of treatment |
IL261756B2 (en) | 2016-03-17 | 2023-11-01 | Thiogenesis Therapeutics Inc | Preparations for the controlled release of cysteamine and systemic treatment of disorders sensitive to cysteamine |
ITUA20161799A1 (it) * | 2016-03-18 | 2017-09-18 | Recordati Ind Chimica E Farmaceutica S P A | Composizione farmaceutica a rilascio prolungato comprendente cisteamina o un suo sale |
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AU2008329628B2 (en) * | 2007-11-30 | 2014-06-26 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products |
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2008
- 2008-11-28 AU AU2008329628A patent/AU2008329628B2/en not_active Ceased
- 2008-11-28 EP EP08853916A patent/EP2214480B1/en active Active
- 2008-11-28 PL PL08853916T patent/PL2214480T3/pl unknown
- 2008-11-28 KR KR1020107013228A patent/KR20100091219A/ko not_active Ceased
- 2008-11-28 US US12/745,504 patent/US7994226B2/en active Active
- 2008-11-28 MX MX2015010032A patent/MX360827B/es unknown
- 2008-11-28 ES ES08853916T patent/ES2417179T3/es active Active
- 2008-11-28 NZ NZ585732A patent/NZ585732A/en not_active IP Right Cessation
- 2008-11-28 TW TW103146662A patent/TWI535435B/zh not_active IP Right Cessation
- 2008-11-28 WO PCT/US2008/085064 patent/WO2009070781A1/en active Application Filing
- 2008-11-28 TW TW097146491A patent/TWI478710B/zh not_active IP Right Cessation
- 2008-11-28 DK DK08853916.8T patent/DK2214480T3/da active
- 2008-11-28 PT PT88539168T patent/PT2214480E/pt unknown
- 2008-11-28 MY MYPI2010002498A patent/MY156316A/en unknown
- 2008-11-28 AR ARP080105211A patent/AR069500A1/es unknown
- 2008-11-28 MX MX2010005921A patent/MX2010005921A/es active IP Right Grant
- 2008-11-28 CA CA2706768A patent/CA2706768C/en not_active Expired - Fee Related
- 2008-11-28 RU RU2010126631/15A patent/RU2498795C2/ru not_active IP Right Cessation
- 2008-11-28 JP JP2010536206A patent/JP5583022B2/ja active Active
- 2008-11-28 SG SG10201403200RA patent/SG10201403200RA/en unknown
- 2008-11-28 CN CN201510122652.7A patent/CN104825430B/zh not_active Expired - Fee Related
- 2008-11-28 EP EP13154059.3A patent/EP2636404B1/en not_active Not-in-force
- 2008-11-28 HR HRP20130590AT patent/HRP20130590T1/hr unknown
- 2008-11-28 CN CN200880125923.2A patent/CN101932238B/zh not_active Expired - Fee Related
- 2008-11-28 BR BRPI0819690A patent/BRPI0819690B8/pt not_active IP Right Cessation
- 2008-12-01 CL CL2008003582A patent/CL2008003582A1/es unknown
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2010
- 2010-05-23 IL IL205909A patent/IL205909B/en active IP Right Grant
- 2010-05-24 ZA ZA2010/03670A patent/ZA201003670B/en unknown
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2011
- 2011-07-15 US US13/183,990 patent/US8263662B2/en active Active
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2012
- 2012-09-10 US US13/608,134 patent/US9149448B2/en active Active
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2013
- 2013-06-27 CY CY20131100522T patent/CY1114126T1/el unknown
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2014
- 2014-07-17 JP JP2014146814A patent/JP6121951B2/ja active Active
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2015
- 2015-09-28 US US14/867,386 patent/US9511038B2/en active Active
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2016
- 2016-11-28 US US15/362,782 patent/US10307386B2/en active Active
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2017
- 2017-03-30 JP JP2017066622A patent/JP2017165735A/ja active Pending
- 2017-09-19 IL IL254586A patent/IL254586A0/en unknown
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