MX2014003643A - Oxi-ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e] azulenos como antagonistas de v1a. - Google Patents

Oxi-ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e] azulenos como antagonistas de v1a.

Info

Publication number: MX2014003643A
Authority: MX; Mexico
Prior art keywords: azulenes; triaza; oxa; benzo; antagonists
Prior art date: 2011-09-26

Application number

MX2014003643A

Other languages

English (en)

Spanish (es)

Inventor

Cosimo Dolente

Patrick Schnider

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-09-26

Filing date

2012-09-24

Publication date

2014-04-30

2012-09-24 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2014-04-30 Publication of MX2014003643A publication Critical patent/MX2014003643A/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Neurology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

MX2014003643A 2011-09-26 2012-09-24 Oxi-ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e] azulenos como antagonistas de v1a. MX2014003643A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP11182796		2011-09-26
PCT/EP2012/068721 WO2013045373A1 (en)	2011-09-26	2012-09-24	Oxy-cyclohexyl-4h,6h-5-oxa-2,3,10b-triaza-benzo[e]azulenes as v1a antagonists

Publications (1)

Publication Number	Publication Date
MX2014003643A true MX2014003643A (es)	2014-04-30

Family

ID=46881068

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX2014003643A MX2014003643A (es)	2011-09-26	2012-09-24	Oxi-ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e] azulenos como antagonistas de v1a.

Country Status (22)

Country	Link
US (1)	US8828989B2 (zh)
EP (1)	EP2760871B1 (zh)
JP (1)	JP5909554B2 (zh)
KR (1)	KR101682777B1 (zh)
CN (1)	CN103827121B (zh)
AR (1)	AR087999A1 (zh)
AU (1)	AU2012314593B2 (zh)
BR (1)	BR112014006945A2 (zh)
CA (1)	CA2844581A1 (zh)
CL (1)	CL2014000717A1 (zh)
CO (1)	CO6870036A2 (zh)
CR (1)	CR20140092A (zh)
EA (1)	EA024990B1 (zh)
EC (1)	ECSP14013271A (zh)
IN (1)	IN2014CN02169A (zh)
MA (1)	MA35535B1 (zh)
MX (1)	MX2014003643A (zh)
PE (1)	PE20141397A1 (zh)
SG (1)	SG2014010607A (zh)
TW (1)	TWI553013B (zh)
UA (1)	UA111623C2 (zh)
WO (1)	WO2013045373A1 (zh)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2360767C (en)	1999-01-19	2009-11-03	Ortho-Mcneil Pharmaceutical, Inc.	Tricyclic benzodiazepines as vasopressin receptor antagonists
US6765004B1 (en)	1999-06-17	2004-07-20	Ortho-Mcneil Pharmaceutical, Inc.	Indoloazepines as vasopressin receptor antagonists
GB0303852D0 (en) *	2003-02-19	2003-03-26	Pfizer Ltd	Triazole compounds useful in therapy
US7119088B2 (en)	2003-02-19	2006-10-10	Pfizer Inc.	Triazole compounds useful in therapy
GB0400700D0 (en) *	2004-01-13	2004-02-18	Pfizer Ltd	Compounds useful in therapy
US7456170B2 (en) *	2004-08-25	2008-11-25	Pfizer Inc.	Triazolobenzodiazepines and their use as vasopressin antagonists
MX2011005119A (es)	2008-11-18	2011-05-30	Hoffmann La Roche	Alquilciclohexileteres de dihidrotetraazabenzoazulenos.
KR101359742B1 (ko) *	2008-11-28	2014-02-06	에프. 호프만-라 로슈 아게	수용체 길항제를 통해 바소프레신으로 사용되는 다이하이드로테트라아자벤조아줄렌의 아릴사이클로헥실에테르

2012
- 2012-08-23 US US13/592,493 patent/US8828989B2/en active Active
- 2012-09-24 AU AU2012314593A patent/AU2012314593B2/en not_active Ceased
- 2012-09-24 MX MX2014003643A patent/MX2014003643A/es unknown
- 2012-09-24 JP JP2014532331A patent/JP5909554B2/ja active Active
- 2012-09-24 IN IN2169CHN2014 patent/IN2014CN02169A/en unknown
- 2012-09-24 EA EA201490558A patent/EA024990B1/ru not_active IP Right Cessation
- 2012-09-24 SG SG2014010607A patent/SG2014010607A/en unknown
- 2012-09-24 BR BR112014006945A patent/BR112014006945A2/pt not_active IP Right Cessation
- 2012-09-24 EP EP12761740.5A patent/EP2760871B1/en active Active
- 2012-09-24 CA CA2844581A patent/CA2844581A1/en not_active Abandoned
- 2012-09-24 UA UAA201403611A patent/UA111623C2/uk unknown
- 2012-09-24 CN CN201280046689.0A patent/CN103827121B/zh active Active
- 2012-09-24 WO PCT/EP2012/068721 patent/WO2013045373A1/en active Application Filing
- 2012-09-24 KR KR1020147010783A patent/KR101682777B1/ko active IP Right Grant
- 2012-09-24 PE PE2014000394A patent/PE20141397A1/es not_active Application Discontinuation
- 2012-09-25 AR ARP120103514A patent/AR087999A1/es unknown
- 2012-09-25 TW TW101135168A patent/TWI553013B/zh not_active IP Right Cessation
2014
- 2014-01-31 CO CO14020668A patent/CO6870036A2/es not_active Application Discontinuation
- 2014-02-26 CR CR20140092A patent/CR20140092A/es unknown
- 2014-03-24 CL CL2014000717A patent/CL2014000717A1/es unknown
- 2014-03-26 EC ECSP14013271 patent/ECSP14013271A/es unknown
- 2014-04-15 MA MA36919A patent/MA35535B1/fr unknown

Also Published As

Publication number	Publication date
UA111623C2 (uk)	2016-05-25
CO6870036A2 (es)	2014-02-20
ECSP14013271A (es)	2014-05-31
KR20140079790A (ko)	2014-06-27
US8828989B2 (en)	2014-09-09
EP2760871A1 (en)	2014-08-06
NZ620653A (en)	2016-03-31
EP2760871B1 (en)	2018-07-18
BR112014006945A2 (pt)	2017-04-04
IN2014CN02169A (zh)	2015-05-29
EA024990B1 (ru)	2016-11-30
TW201315737A (zh)	2013-04-16
US20130079333A1 (en)	2013-03-28
WO2013045373A1 (en)	2013-04-04
PE20141397A1 (es)	2014-10-13
CL2014000717A1 (es)	2014-10-03
AR087999A1 (es)	2014-04-30
CN103827121A (zh)	2014-05-28
CA2844581A1 (en)	2013-04-04
MA35535B1 (fr)	2014-10-02
AU2012314593A1 (en)	2014-02-20
KR101682777B1 (ko)	2016-12-05
CN103827121B (zh)	2016-08-03
EA201490558A1 (ru)	2014-06-30
JP2014527993A (ja)	2014-10-23
AU2012314593B2 (en)	2016-09-29
TWI553013B (zh)	2016-10-11
AU2012314593A8 (en)	2014-03-27
JP5909554B2 (ja)	2016-04-26
SG2014010607A (en)	2014-05-29
CR20140092A (es)	2014-03-20

Publication	Publication Date	Title
NZ603223A (en)	2014-09-26	Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes
MY160457A (en)	2017-03-15	Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes as vasopressin via receptor antagonists
MX2014003600A (es)	2014-04-25	Ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e]azulenos como antagonistas v1a.
BR112012024306A2 (pt)	2016-05-24	aril-cicloexil-tetraazabenzo[e] azulenos
MY160977A (en)	2017-03-31	Heterobiaryl-cyclohexyl-tetraazabenzo[e] azulenes
UA103504C2 (ru)	2013-10-25	Арилциклогексилэфиры дигидротетраазабензоазуленов для применения как антагонистов рецептора вазопрессина v1a
JOP20180103B1 (ar)	2022-03-14	التركيب الصيدلاني للكاربيتوسين
TW200734343A (en)	2007-09-16	Indol-3-yl-carbonyl-spiro-piperidine derivatives
BR112012025942A2 (pt)	2016-06-28	aril-/heteroaril-ciclo-hexenil-tetra-azabenzo[e]azulenos como antagonistas de vasopressina
TW200740792A (en)	2007-11-01	Indol-3-yl-carbonyl-piperidin-benzoimidazol derivatives as V1A receptor antagonists
PH12016500919B1 (en)	2016-06-27	Spiro-oxazolones
MX2016009501A (es)	2016-10-26	Espiro-oxazolonas.
MX2014003643A (es)	2014-04-30	Oxi-ciclohexil-4h,6h-5-oxa-2,3,10b-triaza-benzo[e] azulenos como antagonistas de v1a.
PH12017500891A1 (en)	2017-11-06	Spiro-thiazolones