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MX2011006846A - Virus de fiebre porcina clasico recombinante (csfv) comprendiendo una proteina e2 modificada y metodos para generar dicho csfv. - Google Patents

Virus de fiebre porcina clasico recombinante (csfv) comprendiendo una proteina e2 modificada y metodos para generar dicho csfv.

Info

Publication number
MX2011006846A
MX2011006846A MX2011006846A MX2011006846A MX2011006846A MX 2011006846 A MX2011006846 A MX 2011006846A MX 2011006846 A MX2011006846 A MX 2011006846A MX 2011006846 A MX2011006846 A MX 2011006846A MX 2011006846 A MX2011006846 A MX 2011006846A
Authority
MX
Mexico
Prior art keywords
csfv
recombinant
protein
generating
fever virus
Prior art date
Application number
MX2011006846A
Other languages
English (en)
Inventor
Jeroen Alexander Kortekaas
Rianka Petronella Maria Vloet
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of MX2011006846A publication Critical patent/MX2011006846A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)

Abstract

La invención se refiere a un virus de fiebre porcina clásico recombinante (CSFV). Un CSFV recombinante preferido comprende una supresión de al menos un aminoácido en un dominio "TAVSPTTLR" de la proteína E2. La invención se refiere además a una vacuna comprendiendo el CSFV recombinante, un método para generar un CSFV y uso de un CSFV recombinante.
MX2011006846A 2008-12-23 2009-12-23 Virus de fiebre porcina clasico recombinante (csfv) comprendiendo una proteina e2 modificada y metodos para generar dicho csfv. MX2011006846A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08172874A EP2202298A1 (en) 2008-12-23 2008-12-23 Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV
PCT/NL2009/050801 WO2010074575A2 (en) 2008-12-23 2009-12-23 Recombinant classical swine fever virus (csfv) comprising a modified e2 protein and methods for generating said recombinant csfv.

Publications (1)

Publication Number Publication Date
MX2011006846A true MX2011006846A (es) 2011-09-09

Family

ID=40601213

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011006846A MX2011006846A (es) 2008-12-23 2009-12-23 Virus de fiebre porcina clasico recombinante (csfv) comprendiendo una proteina e2 modificada y metodos para generar dicho csfv.

Country Status (10)

Country Link
US (1) US8911744B2 (es)
EP (2) EP2202298A1 (es)
JP (1) JP5868182B2 (es)
CN (1) CN102317449B (es)
BR (1) BRPI0923599A2 (es)
ES (1) ES2546403T3 (es)
HU (1) HUE025711T2 (es)
MX (1) MX2011006846A (es)
RU (1) RU2501854C2 (es)
WO (1) WO2010074575A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2202298A1 (en) * 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV
WO2011144360A1 (en) 2010-05-18 2011-11-24 Riemser Arzneimittelag Marker vaccine for classical swine fever
CN103751773B (zh) * 2013-07-17 2016-05-18 哈尔滨维科生物技术开发公司 稳定表达猪瘟病毒e0-e1-e2蛋白的重组bhk细胞系及其在制备猪瘟疫苗与诊断试剂中的应用
BR112016014010B1 (pt) * 2013-12-19 2022-08-30 Intervet International B.V. Método para detectar anticorpos contra vírus da febre suína clássica tipo selvagem (csfv) em uma amostra de teste e kit de teste de diagnóstico
DK3146042T3 (da) * 2014-05-23 2019-09-30 Boehringer Ingelheim Vetmedica Gmbh Rekombinant klassisk svinepestvirus (CSFV) med substitution i E2-proteinets TAV-epitop
CN105242044A (zh) * 2015-11-23 2016-01-13 新疆天康畜牧生物技术股份有限公司 猪瘟病毒e2蛋白定量的检测方法
CN107828745B (zh) * 2017-11-15 2021-01-05 中国兽医药品监察所 猪瘟兔化弱毒表位突变株及其应用
CN109781980A (zh) * 2019-01-30 2019-05-21 河南中泽生物工程有限公司 非洲猪瘟病毒快速检测卡及其应用
KR20220009960A (ko) * 2019-04-18 2022-01-25 베링거 잉겔하임 베트메디카 (차이나) 코포레이션 리미티드 재조합 고전적 돼지 열병 바이러스
CN113106071A (zh) * 2020-01-13 2021-07-13 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） Hq06表位突变的猪瘟候选标记疫苗株及其应用
CN111718400B (zh) * 2020-06-15 2021-11-02 苏州世诺生物技术有限公司 猪瘟病毒重组抗原及其制备方法和应用
CN112707948B (zh) * 2020-12-25 2023-03-31 龙湖现代免疫实验室 一条结合猪瘟病毒e0蛋白的多肽序列及应用
CN112625091B (zh) * 2020-12-25 2023-03-31 龙湖现代免疫实验室 一条结合猪瘟病毒Erns蛋白的多肽序列及应用
EP4105225A1 (en) * 2021-06-18 2022-12-21 Institut de Recerca i Tecnologia Agroalimentàries Peptide-based assay to differentiate animals infected with csfv from vaccinated animals
CN113512098B (zh) * 2021-07-15 2022-08-23 武汉大学 鉴别猪瘟病毒和牛病毒性腹泻病毒血清抗体间接elisa方法及其应用
CN114574503B (zh) * 2022-03-14 2024-03-29 成都史纪生物制药有限公司 一种猪瘟E2蛋白基因、猪伪狂犬病毒gD蛋白基因及其应用

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Publication number Priority date Publication date Assignee Title
US5149527A (en) 1990-09-18 1992-09-22 Oncotech, Inc. Immunopotentiating protocol for chemotherapy-responsive tumors
RU2201451C2 (ru) 1994-06-17 2003-03-27 Инститют Вор Дирхаудерей эн Диргезондхейд Нуклеотидная последовательность вируса классической свиной лихорадки (csfv) (варианты), полипептид csfv, пестивирусная вакцина против csfv, диагностический набор и способ
US6316007B1 (en) 1995-04-04 2001-11-13 Wound Healing Of Oklahoma Combined physical and immunotherapy for cancer
EP0924298A1 (en) 1997-12-18 1999-06-23 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Protein expression in baculovirus vector expression systems
JP4620251B2 (ja) 1998-08-10 2011-01-26 アンチジェニックス・インコーポレイテッド Ｃｐｇおよびサポニンアジュバントの組成物並びにその方法
EP1035205A1 (en) * 1999-03-08 2000-09-13 Stichting Dienst Landbouwkundig Onderzoek Non-spreading pestivirus
CA2503303A1 (en) * 2002-11-08 2004-05-27 The Administrators Of The Tulane Educational Fund Flavivirus fusion inhibitors
GB0323968D0 (en) 2003-10-13 2003-11-19 Glaxosmithkline Biolog Sa Immunogenic compositions
US8846055B2 (en) * 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
EP2202298A1 (en) * 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV

Also Published As

Publication number Publication date
WO2010074575A3 (en) 2010-08-26
HUE025711T2 (en) 2016-04-28
JP5868182B2 (ja) 2016-02-24
CN102317449B (zh) 2014-07-23
WO2010074575A2 (en) 2010-07-01
US20110287044A1 (en) 2011-11-24
EP2202298A1 (en) 2010-06-30
RU2501854C2 (ru) 2013-12-20
RU2011130829A (ru) 2013-01-27
ES2546403T3 (es) 2015-09-23
CN102317449A (zh) 2012-01-11
EP2382307B1 (en) 2015-07-15
JP2012513212A (ja) 2012-06-14
BRPI0923599A2 (pt) 2019-09-24
US8911744B2 (en) 2014-12-16
EP2382307A2 (en) 2011-11-02

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