[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ME03726B - Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom - Google Patents

Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom

Info

Publication number
ME03726B
ME03726B MEP-2020-101A MEP2020101A ME03726B ME 03726 B ME03726 B ME 03726B ME P2020101 A MEP2020101 A ME P2020101A ME 03726 B ME03726 B ME 03726B
Authority
ME
Montenegro
Prior art keywords
pain
tetrahydropyrimidodiazepine
tetrahydropyridodiazepine
compounds
related conditions
Prior art date
Application number
MEP-2020-101A
Other languages
German (de)
English (en)
French (fr)
Inventor
Félix Cuevas-Cordobés
Carmen Almansa-Rosales
Original Assignee
Esteve Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Pharmaceuticals Sa filed Critical Esteve Pharmaceuticals Sa
Publication of ME03726B publication Critical patent/ME03726B/me

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-2020-101A 2016-05-06 2017-05-05 Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom ME03726B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16382199 2016-05-06
PCT/EP2017/060780 WO2017191304A1 (en) 2016-05-06 2017-05-05 Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions
EP17721680.1A EP3452475B1 (en) 2016-05-06 2017-05-05 Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions

Publications (1)

Publication Number Publication Date
ME03726B true ME03726B (me) 2021-01-20

Family

ID=56024209

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2020-101A ME03726B (me) 2016-05-06 2017-05-05 Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom

Country Status (32)

Country Link
US (1) US10590140B2 (me)
EP (1) EP3452475B1 (me)
JP (1) JP6926197B2 (me)
KR (1) KR20190024876A (me)
CN (1) CN109526220B (me)
AR (1) AR108387A1 (me)
AU (1) AU2017260305B2 (me)
BR (1) BR112018072755A2 (me)
CA (1) CA3023379A1 (me)
CO (1) CO2018012002A2 (me)
CY (1) CY1123231T1 (me)
DK (1) DK3452475T3 (me)
ES (1) ES2789676T3 (me)
HR (1) HRP20200668T1 (me)
HU (1) HUE051829T2 (me)
IL (1) IL262825A (me)
LT (1) LT3452475T (me)
ME (1) ME03726B (me)
MX (1) MX2018013471A (me)
MY (1) MY196791A (me)
PH (1) PH12018502337A1 (me)
PL (1) PL3452475T3 (me)
PT (1) PT3452475T (me)
RS (1) RS60528B1 (me)
RU (1) RU2018141084A (me)
SG (1) SG11201809799WA (me)
SI (1) SI3452475T1 (me)
TN (1) TN2018000372A1 (me)
TW (1) TWI736619B (me)
UA (1) UA123789C2 (me)
WO (1) WO2017191304A1 (me)
ZA (1) ZA201807653B (me)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111225901B (zh) * 2017-10-16 2023-07-04 埃斯特韦制药股份公司 用于治疗疼痛和与疼痛相关的病症的丙胺衍生物
TW201925179A (zh) * 2017-10-27 2019-07-01 西班牙商艾斯提夫製藥公司 治療疼痛及疼痛相關病症之新型烷氧基胺基衍生物
WO2019110137A1 (en) * 2017-12-04 2019-06-13 Esteve Pharmaceuticals, S.A. O-phenoxy and o-benzyloxypropylamino derivatives having activity against pain
WO2019115008A1 (en) * 2017-12-12 2019-06-20 Esteve Pharmaceuticals, S.A. Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain
WO2019149919A1 (en) * 2018-02-05 2019-08-08 Esteve Pharmaceuticals, S.A. Aminopropoxypiperidinylamido derivatives having multimodal activity against pain
WO2020089263A1 (en) * 2018-10-31 2020-05-07 Esteve Pharmaceuticals, S.A. Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions
EP3873902A1 (en) * 2018-11-02 2021-09-08 Esteve Pharmaceuticals, S.A. New tetrahydropyrimidodiazepin and tetrahydropyridodiazepin compounds for treating pain and pain related conditions
AR116972A1 (es) * 2018-11-02 2021-06-30 Esteve Pharmaceuticals Sa Derivados de alcoxiaminopiridina para tratar dolor y estados relacionados con dolor
CN113661163A (zh) * 2019-02-28 2021-11-16 国立大学法人大阪大学 用于修饰蛋白质和/或肽的分子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2003112257A (ru) * 2000-09-27 2004-10-27 Адзиномото Ко., Инк. (Jp) Производные бензодиазепина
BR0312240A (pt) 2002-06-27 2005-04-12 Warner Lambert Co Método de tratamento do distúrbio por déficit de atenção com hiperatividade
JPWO2005085210A1 (ja) * 2004-03-10 2008-01-17 小野薬品工業株式会社 ニトリル化合物およびその化合物を有効成分として含有する医薬組成物
CN101420955B (zh) * 2006-02-14 2013-07-17 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的二氢二氮杂*
TW200914457A (en) * 2007-05-31 2009-04-01 Kyowa Hakko Kogyo Kk Pyrimidodiazepinone derivative
UY32622A (es) * 2009-05-12 2010-12-31 Astrazeneca Ab Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta)

Also Published As

Publication number Publication date
CY1123231T1 (el) 2021-10-29
DK3452475T3 (da) 2020-04-27
KR20190024876A (ko) 2019-03-08
MX2018013471A (es) 2019-06-06
EP3452475B1 (en) 2020-02-26
BR112018072755A2 (pt) 2019-02-19
RU2018141084A3 (me) 2020-06-11
PL3452475T3 (pl) 2020-08-24
MY196791A (en) 2023-05-03
AU2017260305A1 (en) 2018-12-13
CO2018012002A2 (es) 2019-04-30
TWI736619B (zh) 2021-08-21
PT3452475T (pt) 2020-05-05
SI3452475T1 (sl) 2020-07-31
JP2019515039A (ja) 2019-06-06
CN109526220B (zh) 2021-12-21
LT3452475T (lt) 2020-05-11
EP3452475A1 (en) 2019-03-13
PH12018502337A1 (en) 2019-07-08
JP6926197B2 (ja) 2021-08-25
IL262825A (en) 2018-12-31
HRP20200668T1 (hr) 2020-10-16
RS60528B1 (sr) 2020-08-31
US20190144455A1 (en) 2019-05-16
ZA201807653B (en) 2019-06-26
AR108387A1 (es) 2018-08-15
UA123789C2 (uk) 2021-06-02
ES2789676T3 (es) 2020-10-26
HUE051829T2 (hu) 2021-03-29
CA3023379A1 (en) 2017-11-09
CN109526220A (zh) 2019-03-26
US10590140B2 (en) 2020-03-17
RU2018141084A (ru) 2020-06-08
TN2018000372A1 (en) 2020-06-15
SG11201809799WA (en) 2018-12-28
TW201808955A (zh) 2018-03-16
WO2017191304A1 (en) 2017-11-09
AU2017260305B2 (en) 2021-04-01

Similar Documents

Publication Publication Date Title
ZA201705673B (en) Methods for treating skin
IL269371A (en) Treatment methods
IL262825A (en) Tetrahydropyridine and tetrahydropyrimidine substances, preparations containing them and their use for pain treatment
IL251215A0 (en) Cannabinoid preparation and method for treating pain
GB201608885D0 (en) Treatment
HK1249865B (zh) 疼痛的治療
HK1256174A1 (zh) 用於治療疼痛的 vap-1 抑制劑
EP3507838C0 (fr) Dispositif de traitement de pièces
HK1247119A1 (zh) 一種治療方法和用於所述治療方法中的化合物
SG11201903517RA (en) Composition for alleviating or treating pain
HK1248130A1 (zh) 用於治療疼痛的組合物
ZA202002526B (en) New alcoxyamino derivatives for treating pain and pain related conditions
EP3373947A4 (en) COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN
GB201604658D0 (en) Treatment for pain
IL255012A0 (en) Preparations and methods for treating skin conditions
EP3432884A4 (en) COMBINATIONS FOR THE TREATMENT OF PAIN
PL3129031T3 (pl) Kompozycja do terapii zaburzeń żołądkowych
EP3638223C0 (en) BROMHEXINE FOR THE TREATMENT OF PAIN
GB201706821D0 (en) Compounds and methods for treating obesity
GB201718985D0 (en) Treatment
GB201713650D0 (en) Treatment
GB201706955D0 (en) Treatment
GB201505205D0 (en) Treatment for pain
GB201504688D0 (en) Treatment for pain
GB201617107D0 (en) Treatment