ME03726B - Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom - Google Patents
Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolomInfo
- Publication number
- ME03726B ME03726B MEP-2020-101A MEP2020101A ME03726B ME 03726 B ME03726 B ME 03726B ME P2020101 A MEP2020101 A ME P2020101A ME 03726 B ME03726 B ME 03726B
- Authority
- ME
- Montenegro
- Prior art keywords
- pain
- tetrahydropyrimidodiazepine
- tetrahydropyridodiazepine
- compounds
- related conditions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16382199 | 2016-05-06 | ||
PCT/EP2017/060780 WO2017191304A1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
EP17721680.1A EP3452475B1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
ME03726B true ME03726B (me) | 2021-01-20 |
Family
ID=56024209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2020-101A ME03726B (me) | 2016-05-06 | 2017-05-05 | Jedinjenja tetrahidropirimidodiazepina i tetrahidropirido-diazepina za lečenje bola i stanja povezanih sa bolom |
Country Status (32)
Country | Link |
---|---|
US (1) | US10590140B2 (me) |
EP (1) | EP3452475B1 (me) |
JP (1) | JP6926197B2 (me) |
KR (1) | KR20190024876A (me) |
CN (1) | CN109526220B (me) |
AR (1) | AR108387A1 (me) |
AU (1) | AU2017260305B2 (me) |
BR (1) | BR112018072755A2 (me) |
CA (1) | CA3023379A1 (me) |
CO (1) | CO2018012002A2 (me) |
CY (1) | CY1123231T1 (me) |
DK (1) | DK3452475T3 (me) |
ES (1) | ES2789676T3 (me) |
HR (1) | HRP20200668T1 (me) |
HU (1) | HUE051829T2 (me) |
IL (1) | IL262825A (me) |
LT (1) | LT3452475T (me) |
ME (1) | ME03726B (me) |
MX (1) | MX2018013471A (me) |
MY (1) | MY196791A (me) |
PH (1) | PH12018502337A1 (me) |
PL (1) | PL3452475T3 (me) |
PT (1) | PT3452475T (me) |
RS (1) | RS60528B1 (me) |
RU (1) | RU2018141084A (me) |
SG (1) | SG11201809799WA (me) |
SI (1) | SI3452475T1 (me) |
TN (1) | TN2018000372A1 (me) |
TW (1) | TWI736619B (me) |
UA (1) | UA123789C2 (me) |
WO (1) | WO2017191304A1 (me) |
ZA (1) | ZA201807653B (me) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111225901B (zh) * | 2017-10-16 | 2023-07-04 | 埃斯特韦制药股份公司 | 用于治疗疼痛和与疼痛相关的病症的丙胺衍生物 |
TW201925179A (zh) * | 2017-10-27 | 2019-07-01 | 西班牙商艾斯提夫製藥公司 | 治療疼痛及疼痛相關病症之新型烷氧基胺基衍生物 |
WO2019110137A1 (en) * | 2017-12-04 | 2019-06-13 | Esteve Pharmaceuticals, S.A. | O-phenoxy and o-benzyloxypropylamino derivatives having activity against pain |
WO2019115008A1 (en) * | 2017-12-12 | 2019-06-20 | Esteve Pharmaceuticals, S.A. | Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain |
WO2019149919A1 (en) * | 2018-02-05 | 2019-08-08 | Esteve Pharmaceuticals, S.A. | Aminopropoxypiperidinylamido derivatives having multimodal activity against pain |
WO2020089263A1 (en) * | 2018-10-31 | 2020-05-07 | Esteve Pharmaceuticals, S.A. | Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions |
EP3873902A1 (en) * | 2018-11-02 | 2021-09-08 | Esteve Pharmaceuticals, S.A. | New tetrahydropyrimidodiazepin and tetrahydropyridodiazepin compounds for treating pain and pain related conditions |
AR116972A1 (es) * | 2018-11-02 | 2021-06-30 | Esteve Pharmaceuticals Sa | Derivados de alcoxiaminopiridina para tratar dolor y estados relacionados con dolor |
CN113661163A (zh) * | 2019-02-28 | 2021-11-16 | 国立大学法人大阪大学 | 用于修饰蛋白质和/或肽的分子 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2003112257A (ru) * | 2000-09-27 | 2004-10-27 | Адзиномото Ко., Инк. (Jp) | Производные бензодиазепина |
BR0312240A (pt) | 2002-06-27 | 2005-04-12 | Warner Lambert Co | Método de tratamento do distúrbio por déficit de atenção com hiperatividade |
JPWO2005085210A1 (ja) * | 2004-03-10 | 2008-01-17 | 小野薬品工業株式会社 | ニトリル化合物およびその化合物を有効成分として含有する医薬組成物 |
CN101420955B (zh) * | 2006-02-14 | 2013-07-17 | 沃泰克斯药物股份有限公司 | 可用作蛋白激酶抑制剂的二氢二氮杂* |
TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
UY32622A (es) * | 2009-05-12 | 2010-12-31 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta) |
-
2017
- 2017-05-05 ME MEP-2020-101A patent/ME03726B/me unknown
- 2017-05-05 ES ES17721680T patent/ES2789676T3/es active Active
- 2017-05-05 RS RS20200595A patent/RS60528B1/sr unknown
- 2017-05-05 AU AU2017260305A patent/AU2017260305B2/en not_active Ceased
- 2017-05-05 US US16/098,244 patent/US10590140B2/en active Active
- 2017-05-05 KR KR1020187032195A patent/KR20190024876A/ko not_active Application Discontinuation
- 2017-05-05 PL PL17721680T patent/PL3452475T3/pl unknown
- 2017-05-05 MY MYPI2018704135A patent/MY196791A/en unknown
- 2017-05-05 RU RU2018141084A patent/RU2018141084A/ru unknown
- 2017-05-05 PT PT177216801T patent/PT3452475T/pt unknown
- 2017-05-05 TW TW106114980A patent/TWI736619B/zh not_active IP Right Cessation
- 2017-05-05 AR ARP170101172A patent/AR108387A1/es unknown
- 2017-05-05 SG SG11201809799WA patent/SG11201809799WA/en unknown
- 2017-05-05 JP JP2019510471A patent/JP6926197B2/ja active Active
- 2017-05-05 SI SI201730239T patent/SI3452475T1/sl unknown
- 2017-05-05 CA CA3023379A patent/CA3023379A1/en not_active Abandoned
- 2017-05-05 MX MX2018013471A patent/MX2018013471A/es unknown
- 2017-05-05 CN CN201780042378.XA patent/CN109526220B/zh active Active
- 2017-05-05 DK DK17721680.1T patent/DK3452475T3/da active
- 2017-05-05 BR BR112018072755-5A patent/BR112018072755A2/pt not_active IP Right Cessation
- 2017-05-05 EP EP17721680.1A patent/EP3452475B1/en active Active
- 2017-05-05 WO PCT/EP2017/060780 patent/WO2017191304A1/en unknown
- 2017-05-05 TN TNP/2018/000372A patent/TN2018000372A1/en unknown
- 2017-05-05 HU HUE17721680A patent/HUE051829T2/hu unknown
- 2017-05-05 LT LTEP17721680.1T patent/LT3452475T/lt unknown
- 2017-05-05 UA UAA201811326A patent/UA123789C2/uk unknown
-
2018
- 2018-11-06 PH PH12018502337A patent/PH12018502337A1/en unknown
- 2018-11-06 IL IL262825A patent/IL262825A/en unknown
- 2018-11-14 ZA ZA2018/07653A patent/ZA201807653B/en unknown
- 2018-11-29 CO CONC2018/0012002A patent/CO2018012002A2/es unknown
-
2020
- 2020-04-26 HR HRP20200668TT patent/HRP20200668T1/hr unknown
- 2020-05-25 CY CY20201100472T patent/CY1123231T1/el unknown
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